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[Urinary tract infections and microbiological characteristics of Proteus penneri isolated in Taiwan].

Proteus penneri has been reported to be involved in urinary tract infections and calculi formation. We analyzed 2,265 positive urine cultures from patients hospitalized in Taipei Veterans General Hospital, Taiwan and found that 47 patients (2.1%) were infected by P. penneri. Most of the patients were male with age over sixty and had been treated with various kinds of antibiotics. Most of the patient's urine were collected by catheter. They were alkaline (pH 8.0) and contained amorphous phosphate, triple phosphate and protein. All the isolates of P. penneri in Taiwan showed beta-hemolysis and slight swarming on sheep blood agar plate, and exhibited a green color on upper layer of sulfide-indole-motility medium after addition of Kovacs indole reagent. Except for nitrate reduction and N2 production, the biochemical characteristics of the P. penneri isolated in Taiwan were similar to those of P. penneri isolated otherwise. The Taiwan isolates of this organism were highly susceptible to cefotaxime, cefotazidime, cefotizoxime, moxalactam, nalidixic acid; but were resistant to ampicillin, carbenicillin, cefonicid, cefoperazone, ceftriaxone, cephalexin, cephapirin, chloramphenicol, clindamycin, gentamicin, nitrofurantoin, oxacillin, piperacillin, tetracycline, tobramycin, trimethoprim-sulfamethoxazole, vancomycin, and cephalothin.

Adult↗

A 16-month analysis of urinary tract infection in children.

Results of the examination of urine specimens with evidence of acute urinary tract infections from children aged 16 years and under in general practice were analysed during a period of 16 months. Infections were much commoner in girls than in boys, with Escherichia coli most frequently involved in both groups. Urinary tract infections caused by Proteus strains were predominantly associated with boys. Infections in girls showed a higher incidence at 3, 6 and 16 years of age. Possible reasons for these sex- and age-associated patterns of infection are discussed. It is suggested than an important factor in the prevention of urinary tract infections in young girls is proper supervision of school lavatories. The report illustrates how much useful information can be obtained from the analysis of diagnostic results based on a simple but thorough laboratory approach.

Adolescent↗

Synergistic necrotizing cellulitis of the head and neck.

Synergistic necrotizing cellulitis of the head and neck is a rarely reported virulent infection producing extensive involvement of the subcutaneous tissue and fascia. The reported mortality rate has been approximately 75 per cent. An additional case of a patient experiencing the synergistic effect of infections with an anaerobic streptococcus and a species of Proteus in the head and neck is reported. A review of the pertinent literature is presented.

Adolescent↗

A 12-month fever surveillance study in a veterans' long-stay institution.

This report describes a 12-month fever surveillance survey in a 258-bed veterans long-term care institution. There were 128 episodes of fever (one episode per 24 patient-months); 114 were studied. Lower respiratory tract infections were most frequent, 36 (32%), with 26 (23%) urinary tract infections. Streptococcus pneumoniae was the most common pathogen in the chest infections and Proteus mirabilis the most common of the urinary tract infections. In 40 (35%) there was no evidence of a lower respiratory tract, urinary tract, or other bacterial infection. Most recovered rapidly, many with no specific treatment. There was a 16% mortality associated with the febrile episodes.

Aged↗

Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens.

TWo dosage regimens of cinoxacin, 250 mg. four times a day (QID) versus 500 mg. twice a day (BID), were compared for efficacy and safety in the treatment of initial and recurrent urinary tract infections. Patient dosage assignments were by a random table. Analysis of the 91 evaluable adult patients showed no difference between the two regimens, each group having 98 per cent bacteriologic cures at the five-to-nine-day post-therapy culture. The incidence of side effects was low and mild in degree.

Cinoxacin↗