Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “DERMATOLOGY”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,369 records · Page 76Linked to original sources
PubMed2003

Informed consent in dermatologic surgery.

BACKGROUND: The issue of informed consent retention has not been previously addressed in dermatology literature. Several studies in other fields of medicine have shown that retention rates are below 50%. OBJECTIVE: To determine the percentage of complications recalled at 20 minutes and at 1 week after the informed consent process. METHODS: Eighty-five consecutive patients undergoing Mohs micrographic surgery were given verbal and written instructions, including 10 potential complications. Patients were asked to recall these complications at 20 minutes and at 1 week after the informed consent process. RESULTS: Overall group retention rate at 20 minutes and at 1 week were 26.5% and 24.4%, respectively. CONCLUSION: Patients undergoing elective Mohs micrographic surgery have an overall retention rate of 26.5% just 20 minutes after being informed of 10 possible complications. It is obvious that the informed consent protocol needs additional modalities in order to improve overall retention rates.

Aged↗
PubMed2006

Laser in dermatology.

The laser is a tool that will augment the surgical techniques available to the veterinarian. When using the laser compared with traditional surgery there are multiple procedures that can be performed with much greater ease, and some procedures that previously could not be performed. Specialty and academic practices have used lasers for photodynamic therapy, lithotripsy of urinary calculi, and percutaneous disk ablation. This article will focus on the lasers use in dermatology. It is essential that the surgeon learn the basics of laser physics, how the laser interacts with tissue and the safety issues one needs to consider during its use. On deciding to use the laser the surgical techniques chosen should always be based on considering the advantages and disadvantages the laser has to offer. The use of biomedical lasers is a "cutting edge" technique now available to our veterinary field.

Animals↗
PubMed2000

Antimicrobial prophylaxis in dermatology.

Few circumstances in dermatology warrant antimicrobial prophylaxis. In cutaneous surgery postoperative infections are too infrequent and insufficiently severe to justify preventive antibiotics, except rarely. Petrolatum is as effective as, and cheaper than, topical antibiotic ointment to cover surgical wounds. In patients with numerous staphylococcal skin infections, oral clindamycin 150 mg every day for 3 months safely reduces further episodes. For recurrent cellulitis, oral penicillin or erythromycin 250 mg twice daily or monthly intramuscular benzathine penicillin decreases subsequent attacks. In patients with frequent episodes of genital or labial herpes simplex an antiviral agent such as valacyclovir 500 mg to 1 g every day is effective as a suppressant.

Anti-Bacterial Agents↗
PubMed2002

Practical applications of hand-held computers in dermatology.

For physicians, hand-held computers are gaining popularity as point of care reference tools. The convergence of hand-held computers, the Internet, and wireless networks will enable these devices to assume more essential roles as mobile transmitters and receivers of digital medical Information. In addition to serving as portable medical reference sources, these devices can be Internet-enabled, allowing them to communicate over wireless wide and local area networks. With enhanced wireless connectivity, hand-held computers can be used at the point of patient care for charge capture, electronic prescribing, laboratory test ordering, laboratory result retrieval, web access, e-mail communication, and other clinical and administrative tasks. Physicians In virtually every medical specialty have begun using these devices in various ways. This review of hand-held computer use in dermatology illustrates practical examples of the many different ways hand-held computers can be effectively used by the practicing dermatologist.

Computers, Handheld↗
PubMed2005

[A common and insidious side-effect: allergic contact dermatitis caused by bufexamac used in the treatment of dermatitis. Results from the Information Network of Departments of Dermatology (IDVK)].

BACKGROUND AND OBJECTIVE: Bufexamac is a non-steroidal, anti-inflammatory drug used in the topical treatment of atopic dermatitis, stasis dermatitis and perianal eczema. The substance is known to cause severe allergic contact dermatitis (ACD) as an adverse effect (AE), which may be indistinguishable from the eczema which is to be treated. Hence the diagnosis of this AE is often considerably delayed. In order to estimate the quantitative importance of ACD to bufexamac, data of the Information Network of (German) Departments of Dermatology (IVDK) from July 1999 to December 2004 were analysed. PATIENTS AND METHODS: During the study period, 39,392 unselected patients from 40 German departments of the IVDK were patch tested with bufexamac (5 % pet). The results of the reading after 72 hours were analysed. The dichotomized patch test result was further assessed for possible risk factors from the patients' history and clinical diagnosis by Poisson regression analysis. RESULTS: In 560 of 39,392 patients contact allergy to bufexamac was diagnosed, i. e. 1.4 % (95 % confidence interval: 1.3 - 1.5), standardized for sex and age. The Poisson regression analysis revealed a significantly increased risk associated with the following factors: multiple sensitization, perianal eczema, underlying atopic dermatitis, leg dermatitis, female gender and residence in areas of Germany other than Eastern Germany. The latter observation can be explained by low prescription rates in Eastern Germany. CONCLUSION: Bufexamac is an important allergen. Extrapolating the frequency of 1.4 % in our data to the whole German population by the CE-DUR approach yields an estimate of about 6000 cases per year. In view of the high frequency of sensitization, the pitfalls in diagnosis, the severity of the course of disease and the lack of efficacy of this drug, the risk to benefit ratio is obviously critical.

Administration, Topical↗
PubMed1987

[Eye diseases attributable to dermatologic therapy].

This paper presents a general review of iatrogenic ocular conditions which can be related to dermatologic treatment. Among others, those ocular conditions are described which are attributable to sulfonamides, antibiotics, antituberculosis medication, corticoids, chloroquinine, chlorpromazine, allopurinol, iodoquinoleins, monobenzone, antineoplastics, and radiotherapy in the paraorbital regions.

Antineoplastic Agents↗
PubMed2000

The dermatology-industry interface: defining the boundaries.

Support from industry has become an important factor in the growth of the dermatologic profession. However, the relationship creates inevitable conflicts of interest. This article explores these potential conflicts, including (1) giving and receiving of gifts, (2) conduct of clinical trials, (3) appearance of advertisements in professional journals, (4) continuing medical education programs and educational grants to societies and departments, and (5) drug sampling.

Advertising↗
PubMed2000

CADASIL: the dermatologic diagnosis of a neurologic disease. Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an increasingly recognized neurologic disease characterized by pathognomonic changes to the small vessels, particularly in the brain and skin. Although much has recently been written about this disease in the neuropathology literature, to our knowledge nothing has appeared in the dermatology literature. We wish to call attention to the unique role dermatologists and dermatopathologists can play in the diagnosis of this disease. We review the condition's clinical, histologic, and ultrastructural features.

Biopsy, Needle↗
PubMed2001

Patients seen in a dermatology clinic have unmet preventive health care needs.

Dermatologists provide special expertise in the care of patients with skin disease, whereas primary care providers have special expertise in preventive care. Patients bypassing their primary care provider to use dermatologists directly may miss an opportunity for identification of preventive health needs. We conducted a pilot study to determine whether patients seeing a dermatologist have unmet general preventive health care needs. A 1-page assessment was developed in accordance with the US Preventive Services Task Force guidelines and was distributed to a convenience sample of 161 patients in a dermatology clinic. Unmet needs were identified in the areas of screening tests, counseling, immunizations, vitamins, and replacement hormones. Of subjects aged 25 to 64 years, 94% without a primary care provider had unmet needs compared with 28% of subjects with a primary care provider. We found that patients seeing a dermatologist often had unmet preventive health needs. Dermatologists and primary care providers must work together to provide optimal skin care and preventive health care needs for the patient.

Adolescent↗
PubMed2001

Dermatology in primary care: Prevalence and patient disposition.

BACKGROUND: Cutaneous disease is commonly encountered in primary care. The frequency of patients presenting to primary care physicians with skin disease and their eventual disposition is not well studied. OBJECTIVE: The purpose of this study was to determine the prevalence of patients seen with skin disease in a primary care setting and the likelihood of their referral to a dermatologist. The impact the primary care provider had on the quality of skin care was also examined. METHODS: A retrospective chart review was performed of patients seen during a 2-year period at a general medicine clinic within the University of Miami and upon referral to a University of Miami dermatology office. Data were obtained on the prevalence of skin disease, dispositions of referral, diagnoses made, and procedures performed. RESULTS: During a 2-year period, 36.5% of patients who presented to their primary care physician had at least one skin problem. Of 208 patients with skin disease, in 58.7% (122/208) it was their chief complaint. A wide range of diagnoses were made by the primary care physician, with a limited number of diagnostic procedures performed. Of the 37.5% of patients referred to a dermatologist, 68% were referred on initial evaluation. Diagnoses made by the primary care physician were concordant with that made by the dermatologists 57% of the time. CONCLUSION: Patients frequently see their primary care physician for skin disease. A large percentage are referred to dermatologists, often for a biopsy of a suspect lesion, to confirm a suspected diagnosis, or to establish a diagnosis of lesions of unknown origin.

Adult↗
PubMed2002

Management of dysplastic nevi: a survey of fellows of the American Academy of Dermatology.

BACKGROUND: Opinions concerning the significance of dysplastic nevi and their management vary among dermatologists. OBJECTIVE: The purpose of this study was to assess how fellows of the American Academy of Dermatology (AAD) perceive and manage dysplastic nevi. METHODS: Questionnaires were sent to 1216 fellows of the AAD; 456 questionnaires were returned. RESULTS: Almost all respondents (98%) accept the dysplastic nevus, or atypical mole, as an entity. Seventy-five percent of respondents perform follow-up total cutaneous examinations on all their patients with dysplastic nevi, and another 22% on some of them; 86% usually intend to do total removals when they perform biopsies of dysplastic nevi; 75% use margins of 2 mm or less when removing dysplastic nevi; 49% order baseline total-cutaneous photographs of some or all of their patients with multiple dysplastic nevi, although only 12% do so routinely; 67% prefer to re-excise dysplastic nevi when margins are positive, some using histologic atypia as a criterion; 60% recommend an ophthalmologic examination for at least some of their patients with many dysplastic nevi, although only 3% do so routinely; 12% always recommend cutaneous examinations of blood relatives of their patients with dysplastic nevi and another 81% recommend such examinations for at least some of their patients with dysplastic nevi; 23% use dermoscopy; 99% recommend self-examination; almost 100% recommend sunscreen use and 93%, sun avoidance. CONCLUSION: Most respondents, in agreement with the literature, accept the concept that patients with dysplastic nevi are at increased risk for melanoma and that methods for prevention and early detection of melanomas are appropriate for these patients.

Attitude of Health Personnel↗
PubMed2003

Patients' attitudes toward medical student participation in a dermatology clinic.

To study the attitudes of patients toward medical student participation in a dermatology clinic, we surveyed 208 volunteer adult outpatients at a university setting. Almost all patients (98.5%) had no preference regarding medical student participation in their care or prefer medical student participation in their care. The majority of patients (84.5%) felt comfortable disclosing personal information to the medical student. Most patients (94.2%) enjoyed the interaction with the medical student, 22% of patients wanted time alone with the physician, and 91.8% of patients agreed that the students understood their health care needs. The majority of patients in this study enjoyed their interactions with the students and felt comfortable disclosing information. Some patients want to spend time alone with the physician. Permission for medical student participation should be requested.

Adult↗
PubMed2002

The Norwegian version of the dermatology life quality index: a study of validity and reliability in psoriatics.

The aim of this study was to test the Norwegian version of the Dermatology Life Quality Index (DLQI-N) for validity and reliability in psoriatic patients. The DLQI-N was administered to 230 patients with psoriasis who underwent climate therapy on Gran Canaria, with a dermatologist assessing their psoriasis severity using the Psoriasis Area and Severity Index. Factor analyses resulted in a unidimensional pattern, which supports the use of a total DLQI-N score. The internal consistency coefficient of this unidimensional measure was 0.90 (Cronbach's alpha) and the paired inter-item correlations ranged from 0.20 to 0.76 (p < 0.01). Questions related to work, sport and sex were the issues most often ticked off as not relevant, and the item related to working/studying was often misunderstood. DLQI-N scores were significantly associated with disease severity, age and sex. We assess DLQI-N as a valid, reliable and clinically useful outcome measure for quality of life in Norwegian patients with psoriasis.

Age Distribution↗
PubMed1991

Office dermatologic surgery and laser therapy.

As the result of a dramatic increase in the incidence of skin cancer and the need for effective outpatient surgical treatment, dermatology is now a surgical as well as a medical specialty, and many procedures are commonly performed on an outpatient basis. Mohs micrographic surgery is used to remove basal cell and squamous cell carcinomas, and the resulting cure rates are high. Excisional biopsy can facilitate the early diagnosis of melanoma, while it is still in clinical stage I. Carbon dioxide lasers are commonly used to destroy epidermal lesions and yellow light lasers to destroy hemangiomas or other vascular malformations. Facial chemical peel (chemexfoliation) with trichloroacetic acid can improve the appearance of photoaged skin.

Biopsy↗
PubMed2006

Gender: a possible determinant in dosing of dermatologic drugs--an overview.

The role of gender in pharmacokinetics could play a significant role in tailoring HIV and other drug regimens. Here we investigate sex as a factor in saquinavir pharmacokinetics. The HIV-positive women who use saquinavir in combination with other protease inhibitors frequently demonstrate higher saquinavir concentrations than their male counterparts. The majority of the data indicates that the root of women's higher saquinavir concentrations is not inherent to their gender. Rather, extenuating factors associated with HIV play a prominent role in the observed difference between men and women's pharmacokinetic parameters. The source of observed differences in saquinavir pharmacokinetics could not be definitively traced to CYP3A, the enzyme responsible for saquinavir's metabolism or drug transporters. Hormonal changes associated with HIV infection together with concurrent use of other protease inhibitors could help explain development of sex differences. These findings can be used to further investigate when and why gender-based differences in saquinavir pharmacokinetics exist and possible future dosage and therapy considerations. Our knowledge of gender-related pharmacokinetics should be extended for other systemic drugs in dermatology.

ATP Binding Cassette Transporter, Subfamily B, Mem↗
PubMed2003

Online consumer health education in dermatology.

Comprehensive and accurate health information for the consumer has the potential to improve patient care and health outcomes. NZDermNet, the web site of the New Zealand Dermatological Society, was established in 1996. Its consumer health information section includes more than 250 pages of information about skin diseases and their treatment. It has proven popular with health professionals and patients. In 2002 an average of more than 5000 visitors used the site daily.

Dermatology↗
PubMed2006

DNA microarrays in dermatology and skin biology.

Because of its accessibility, skin has been among the first organs analyzed using DNA microarrays. Skin cancers, melanomas, and basal and squamous cell carcinomas have been intensely investigated because they are very frequent and can be fatal. Psoriasis, one of the most common human inflammatory diseases, has been studied comprehensively using DNA microarrays. In addition, epidermal keratinocytes have been the target of many studies because they respond to a rich variety of inflammatory and immunomodulating cytokines, hormones, vitamins, ultraviolet (UV) light, toxins, and physical injury. Because of the ethical considerations, the effects of harmful or dangerous agents on skin have been studied using artificial skin substitutes. Transcriptional mechanisms that regulate epidermal differentiation and cornification have begun to yield their mysteries, and very exciting recent studies identified the genes specifically expressed in epidermal stem cells. Thus, skin has everything: stem cells, differentiation, signaling, inflammation, diseases, and cancer. All these exciting facets of skin have been explored using DNA microarrays. Researchers in skin biology and dermatology were among the first to implement this technology and we expect that they will continue to generate exciting and useful new knowledge.

Animals↗
PubMed2004

Dermatologic terms in the onomasticon of Julius Pollux.

In the second century C.E., the Greco-Roman rhetorician Julius Pollux compiled lists of technical terms in Attic Greek pertaining to many specialized topics, including dermatology. This article reproduces his catalogue of almost 100 terms referring to cutaneous and mucosal lesions and translates his explanatory comments into English.

Dermatology↗