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At least 1,351 records · Page 75Linked to original sources
PubMed2002

A prediction model for the incidence patterns of female breast cancers in Alexandria, Egypt.

Breast cancer is the most common cancer among women in the world. Female breast cancer incidence has historically increased all over the world during the past decades. The purpose of this study was to estimate the patterns of female breast cancer incidence in Alexandria, Egypt, from 1972 to 2001. An up-to-date perspective systematically collected data on the incidence of female breast cancers was used. Age categories-estimated incidence over the 30 years period were computed. Time series analysis showed that incidence of breast cancers is increasing significantly during the studied period. Linear trend model was best fitted, with the studied interval and the estimated cancer cases per year taken into account. Age-incidence correlation showed a high correlation between age group of 40-50 years old and incidence. Analysis of the patterns for cancer incidence indicates that the highest occurrence of female breast cancer is shown in the age category of 45-50 years followed respectively by the age categories of 40-45 years, 50-55 years, 35-40 years and then 55-60 years. These findings support the growing body of evidence from female breast cancer incidence suggesting that age is a well-known risk factor for breast cancer susceptibility.

Adult↗
PubMed1991

Multivariable prediction model for the need for surgery in horses with colic.

A survey of 1,965 equine colic cases was conducted from August 1985 to July 1986 at 10 equine referral centers located throughout the United States. The purpose of this study was to develop and validate a multivariable model for the need for surgery. Two-thirds of the cases were randomly selected for model development (1,336), whereas the remaining cases (629) were used only for subsequent validation of the model. If a lesion requiring surgical correction was found at either surgery or necropsy, the case for the horse was classified as surgical, otherwise the case was classified as medical. Only variables that were significant (P less than 0.05) in an initial bivariable screening procedure were considered in the model development. Because of the large number of missing values in the data set, only variables for which there were less than 400 missing values were considered in the multivariable analysis. A multivariable logistic regression model was constructed by use of a stepwise algorithm. The model used 640 cases and included variables: rectal findings, signs of abdominal pain, peripheral pulse strength, and abdominal sounds. The likelihood ratio for surgery was calculated for each horse in the validation data set, using the logistic regression equation. Using Bayes theorem, the posttest probability was calculated, using the likelihood ratio as the test odds and the prevalence of surgery cases (at each institution) as an estimate of the pretest odds. A Hosmer-Lemeshow goodness-of-fit chi 2 statistic indicated that the model fit the validation data set poorly, as demonstrated by the large chi 2 value of 26.7 (P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1987

Progress toward predictive models for the outcome of treatment for acute nonlymphocytic leukemia.

A prognostic factor model for "high risk" patients (those more than 70 years old or with secondary leukemia) which involves the serum albumin and platelet count has recently been reported. This model permits the division of the "high risk" patient group into those with an 80% likelihood of surviving high-dose cytosine arabinoside therapy and those with a greater than 70% likelihood of dying.

Antineoplastic Combined Chemotherapy Protocols↗
PubMedDate not supplied

The use of predictive modeling to test nursing practice outcomes.

A middle range, multivariate practice model was constructed to test the impact of a perioperative teaching program on multiple patient outcomes: coping, anxiety, recovery pattern, pain, and patient satisfaction. In addition, the influence of such a program on nursing staff was examined. A quasi-experimental, causal modeling approach was used. The operative trajectory of 88 patients and their operating room nursing staff was traced from two pre-operative points through the intra-operative stage to two points post-operatively. The experimental patients (n = 54) evidenced higher satisfaction with their care, a tendency to experience less post-operative vomiting, but also tended to recover more slowly and cope less well than the control patients (n = 34). Multiple regression analysis of the practice model suggested the perioperative teaching program affected patient outcomes, indirectly, through the functioning of the staff nurses intra-operatively.

Adolescent↗