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Radiological assessment of bone segments for transplantation: experience at Rizzoli Orthopedic Institute.

AIM: To analyse results obtained from radiological assessment of skeletal segments stored in the musculoskeletal tissue bank (MTB) at Rizzoli Orthopaedic Institute. MATERIALS AND METHODS: Between January 1997 and June 2003, 891 bone segments underwent radiographic examination in two views. Two hundred and thirteen of these segments were examined by a radiologist between July 2002 and June 2003. Diagnostic evaluation was aimed at recognising relevant degenerative, traumatic and focal lesions. Focal lesions underwent histological tests. RESULTS: Twenty-two lytic lesions were found in 12 segments. Ten of these were studied between July 2002 and June 2003 and two in the period before specialist radiological assessment. In the latter cases the lesions were identified by the orthopedic specialist who had examined the X-rays before planning surgery. Histological tests showed that the bone tissue was normal or involved by degenerative phenomena. CONCLUSIONS: We think donor screening should include radiological assessment of bone segments, performed according to standard parameters by a radiologist to identify bone lesions that may jeopardise the successful outcome of surgery.

Adolescent↗

Effectiveness of a discharge-planning pilot program for orthopedic patients in Taiwan.

The purpose of this pilot project was to establish a discharge-planning model and evaluate its effectiveness. Orthopedic patients who scored 7 or above on a high-risk screening form were recruited for the project. Case managers served as discharge planners, and handled the following procedures: screening of patients, drawing up of the discharge plan, providing pre-discharge instructions, coordinating resources and services, and telephone follow-up. Results showed that discharge planning improved both the completion rate of pre-discharge instructions and patient satisfaction with discharge planning. It is suggested that, in future research, experimental studies could be used to examine the effectiveness of discharge planning. The study showed the importance of dedicated case managers for improving the effectiveness of discharge planning.

Aged↗

Geometry of human ribs pertinent to orthopedic chest-wall reconstruction.

Orthopedic reconstruction of blunt chest trauma can aid restoration of pulmonary function to reduce the mortality associated with serial rib fractures and flail chest injuries. Contemporary chest wall reconstruction requires contouring of generic plates to the complex surface geometry of ribs. This study established a biometric foundation to generate specialized, anatomically contoured osteosynthesis hardware for rib fracture fixation. On human cadaveric ribs three through nine, the surface geometry pertinent to anatomically conforming osteosynthesis plates was characterized by quantifying the apparent rib curvature C(A), the longitudinal twist alpha(LT) along the diaphysis, and the unrolled curvature C(U). In addition, the rib cross-sectional geometry pertinent to intramedullary fixation strategies was characterized in terms of cross-section height, width, area, and cortex thickness. The rib surface exhibited a curvature C(A) ranging from 3.8 m(-1) in the anteromedial section of rib seven to 17.3 m(-1) in the posterior section of rib three. All ribs had in common a longitudinal twist alpha(LT), ranging from 41-60 degrees. The unrolled curvature C(U) decreased gradually from ribs three to five, and increased gradually with reversed orientation from rib six to nine. The cross-sectional area remained constant along the rib diaphysis. However, the medullary canal increased in size from 29.9 mm(2) posteriorly to 41.2 mm(2) in anterior rib segments. Results of this biometric rib characterization describe a novel strategy for intraoperative plate contouring and provide a foundation for the development of specialized rib osteosynthesis strategies.

Bone Plates↗

Role of radionuclide imaging in the orthopedic patient.

Since its introduction more than 40 years ago, nuclear medicine has played an important role in the diagnosis and detection of soft tissue and skeletal disorders. Skeletal scintigraphy or bone scanning is a diagnostic study used to evaluate the distribution of osteoblastic activity or active bone formation within the body. Because no single imaging technique is ideal in all clinical situations, selecting an appropriate imaging test depends on understanding the pathophysiology of the suspected condition and limitations of each technique. This article provides a brief overview of bone scintigraphy, infection imaging, and positron emission tomography in the context of current, adult orthopedic practice.

Bone Diseases↗

[Orthopedic manifestations of the antiphospholipid syndrome].

PURPOSE: The antiphospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis, and pregnancy morbidity in association with antiphospholipid antibodies. Since its classical description 22 years ago, the clinical spectrum of APS has embraced the realms of obstetrics, nephrology, cardiology, neurology, gastroenterology, angiology and now, possibly orthopaedics. This is not surprising given that this disease can affect virtually any organ system and blood vessel of any size and nature. Just as venous thrombosis may affect limbs and internal organs, arterial thrombosis has been shown to affect organs such as the brain, eye, heart, kidney, liver and may also involve the skeleton. CURRENT KNOWLEDGE AND KEY POINTS: In this review, we describe the orthopedic aspects of APS recently reported, bone metatarsal fractures, osteonecrosis and more exceptional complications, ie algodystrophy and bone marrow necrosis. We briefly discuss postulated pathogenesis and possible implications of anticoagulation. FUTURE PROSPECTS AND PROJECTS: This data need further confirmation. They may suggest complementary physiopathologic and therapeutic implications.

Antiphospholipid Syndrome↗

Postoperative orthopedic autotransfusion. Successful management for the total knee arthroplasty patient.

Orthopedic autotransfusion is an effective technique that should be available to patients having total knee arthroplasty. Patient safety, however, must not be compromised simply because the blood is autologous. Blood products, in any form, require close observation and careful administration. The best results are achieved when the physician and all nursing departments involved have comprehensive knowledge of the system and the guidelines for its safe use.

Blood Transfusion, Autologous↗

Technical considerations for optimal orthopedic imaging.

Over the past 25 years bone scintigraphy has played an essential role in most Nuclear Medicine departments, accounting for 25% to 60% of the patient volumes. No longer is every bone scan ordered as part of a metastatic workup. Today radionuclide bone imaging (RNBI) is included in most orthopedic diagnostic pathways. It is necessary to optimize the bone scan procedure to be sensitive, to carefully localize abnormal uptake for diagnosis, to correlate the bone scans, plain radiographs, computed tomographic (CT) scans, and magnetic resonance (MR) scans that accompany the patient, and to be precise in reporting a final impression. This can be done through meticulous attention to the image acquisition so that it encompasses not only equipment specifications and acquisition parameters, but also patient history, preparation, imaging protocols, positioning, and image correlation. The importance of these considerations, the rationale to explain them, and suggested guidelines for their implementation will be discussed in this article.

Bone Diseases↗

Orthopedic pathology of the lower extremities: scintigraphic evaluation in the thigh, knee, and leg.

Radionuclide imaging (RI) of the osseous and nonosseous structures of the thigh, knee, and leg provide important diagnostic and prognostic information upon which the orthopedic surgeon can base treatment planning and management decisions. 99mTc-MDP scintigraphy is essential in overuse injuries such as stress fractures and shin splints. RI is important in assessing complications of trauma. It is the only imaging modality able to assess the magnitude of physeal stimulus caused by femoral fractures and to predict a favorable or unfavorable outcome of leg length by semiquantitative analysis; SPECT imaging can detect and locate decreased metabolism associated with posttraumatic closure of the physeal plate to predict growth arrest and deformities. Three-phase bone imaging (TPBI) is essential to differentiate hypervascular from avascular nonunions and follow delayed union. In osteonecrosis of the knee, bone scintigraphy precedes radiography changes even in stage l of the disease. 99mTc-MDP and 99mTc-HIG imaging are powerful tools in determining the outcomes of osteoarthritis and rheumatoid arthritis, respectively. Bone scintigraphy can also detect chronic ligament and acute and chronic meniscal lesions. The combined use of TPBI, gallium-67 citrate imaging, and indium-111 or 99mTc-HMPAO labeled leukocytes is important to diagnose and differentiate acute from chronic osteomyelitis, and to detect infected knee prostheses. Thallium-201 chloride imaging and 99mTc-sestamibi imaging have an important role in the assessment of tumor response to chemotherapy and in the quantification of tumor viability.

Bone Diseases↗

Nuclear medicine in pediatric orthopedics.

In this presentation, the common clinical pediatric problems (appendicular growth aberrations, hip pain, back pain, some aspects of trauma, and inflammatory and infectious processes that can be addressed by nuclear imaging will be discussed. The accurate interpretation of bone scintigraphy in the evaluation of pediatric orthopedic conditions depends on the use of appropriate radiopharmaceuticals and imaging techniques specific for the pediatric population, a knowledge of physiologic changes in the growing skeleton, as well as the different disease processes peculiar to each age bracket. The physes (growth-plates) will be discussed in detail because they are the most active portion of the pediatric skeleton. Their activity (potential for growth) can be altered by physiologic, developmental aberrations (varus and valgus) and pathologic conditions (trauma, infection, etc.).

Adolescent↗

Orthopedic effects with "conventional" fixed orthodontic appliances: a preliminary report.

This retrospective study involved sixty previously treated patients between the ages of 9 and 14 years, all of whom initially had Class II dental malocclusions. The primary purpose of the investigation was to determine whether orthodontic treatment with a specific round-wire edgewise technique (no extraoral forces) was simply producing dentoalveolar manipulations or was actually affecting measurable skeletal or orthopedic alterations in the craniofacial system. The mean linear changes before and after orthodontic treatment in the maxilla (Ar-ANS), mandible (Ar-PGN), and lower facial height (ANS-MN) were statistically compared with an untreated control group (the Burlington Growth Study). The study sample was analyzed selectively according to sex and also according to the angulation of the mandibular base to the anterior cranial base (the SNMP angle). Apparently, from the observations in this study, the particular edgewise technique employed for the orthodontic treatment of the sixty sample patients did statistically affect more than merely dentoalveolar alterations. The normal forward growth of the maxilla appeared to be hindered, the lower facial height was significantly increased (usually without an appreciable increase in the SNMP angle), and the mean increased growth of the mandible was also statistically significant. Admittedly not its primary purpose, this preliminary report appeared to at least indirectly compare, if not the actual treatment modalities, at least the treatment results between a specific fixed orthodontic appliance and certain removable "functional" appliances.

Adolescent↗

Use of botulinum toxin type A on orthopedics: a case report.

Botulinum toxin type A is effective in treating neurologic entities with increased muscle tone. Few reports show the benefits of this treatment for orthopedic conditions. We present the case of a 54-year-old man who manifested bilateral pectoralis major stiffness and bilateral shoulder pain; he had a score of 6 on a visual analog scale (VAS). Complex regional pain syndrome (type I) after cardiac surgery, which had already been resolved, was significant in the patient's clinical background. On examination, neither increases in muscle tone nor signs of tendinous or joint pathology was found. However, the patient experienced significant pain when both pectorals were stretched. The patient's Constant score, a validated scale of shoulder function, was 45/100 on the right shoulder and 41/100 on the left. The patient's shoulder stiffness and pain neither responded to rehabilitation (stretching exercises, passive mobilization, electrostimulation) nor to oral medication (alprazolam, gabapentin). Despite the lack of increased muscle tone, we decided to administer botulinum toxin type A to control pain. Subsequently, pain intensity was reduced to 4 on a VAS on both sides, and functionality improved (Constant scale score, 62 on the right side; 60 on the left). This improvement enabled the patient to resume his job as a building supervisor, which required active involvement in physical construction work.

Botulinum Toxins, Type A↗

Orthopedic management of the patient with a spinal injury.

I have tried to make clear that there are no absolute principles in the orthopedic management of patients with a spinal cord injury. Although debate continues regarding the approach to the problem, the goals remain optimal patient care, free of complications, and preparation for a smooth transition of the patient into a new life with handicaps. Most strides in spinal cord injury care have been made in improvement of internal fixation and immobilization, advances in rehabilitation techniques and marked shortening of hospitalization. Active research continues to investigate the pathophysiology of the injury and a means of reversing or impeding the damage to neural tissue. Currently, certain spinal cord injuries are considered irreversible despite treatment with spinal cord hypothermia, reanastomosis of spinal cords or administration of enzyme injections. The person with a spinal cord injury and paralysis rarely loses the hope that a cure might be the next great discovery of medical science and active spinal cord injury research centers have the same goal.

Adult↗

An intelligibility assessment of toddlers with cleft lip and palate who received and did not receive presurgical infant orthopedic treatment.

A randomized, prospective, clinical study was performed investigating the effects of presurgical infant orthopedic treatment (PIO) in children with unilateral cleft lip and palate (UCLP). The influence of PIO on speech intelligibility was evaluated with two groups, each consisting of 10 children with UCLP. One group used PIO during the first year of life, whereas the other group did not use the device. Eight children without cleft served as a second control group. Intelligibility was assessed by lay listeners using two methods: transcription and listener rating. The ratings proved to be reliable and to have sufficient validity, but they did not completely reflect intelligibility defined as the proportion of words understood by the listener. Children in the treatment group were rated as exhibiting greater intelligibility than those in the nontreatment group. However, data obtained by means of transcriptions indicated that, in fact, there were no group differences in actual intelligibility. Only in comparison with their noncleft peers were the children with cleft lip and palate significantly less well understood.

Articulation Disorders↗

Update. Deep vein thrombosis and pulmonary embolism prophylaxis in orthopedic surgery.

Deep vein thrombosis and pulmonary embolism continue to be controversial areas for prophylaxis in orthopedic surgery. This patient population continues to have the highest incidence of deep vein thrombosis and pulmonary embolism when inappropriately or not prophylaxis for this complication. This article reviews the current modalities for prophylaxis with respect to their safety and efficacy. In addition, the new modalities of low molecular weight heparin and arteriovenous impulse system are presented.

Anticoagulants↗

Update on imaging of orthopedic infections.

Although the diagnosis of infection is only a small part of the orthopedist's job description, it is a important part. This article discusses the fundamentals of orthopedic infections and highlights the refinements on this topic from a radiologic perspective. In addition to reviewing the imaging appearance of musculoskeletal infections in bone and the surrounding soft tissues, we focus on the advantages and disadvantages of five imaging methods: radiography, sonography, CT, scintigraphy, and MR imaging. Finally, we review three specific situations that have garnered substantial attention in recent medical literature: chronic recurrent multifocal osteomyelitis, musculoskeletal infections in AIDS patients, and pedal infections in diabetic patients.

Diabetic Foot↗

Selected topics in orthopedic nuclear medicine.

Nuclear medicine provides information about bone physiology that complements anatomic imaging modalities. Following a review of the principles of bone scintigraphy, scintigraphic imaging of orthopedic problems, such as primary and secondary neoplastic disease of the skeleton, occult fracture, stress fracture, and osteomyelitis are discussed.

Bone Diseases↗

Orthopedic conditions of the cervical spine and shoulder.

Orthopedic conditions of the cervical spine and shoulder can range from benign to life threatening. A careful history and examination are crucial to evaluate these children, and additional investigations may be necessary. The signs and symptoms in these conditions and the indications for referral are discussed.

Atlanto-Axial Joint↗

Topics of interest in pediatric orthopedics.

This two-in-one article presents an overview of septic arthritis of the hip and school screening for adolescent idiopathic scoliosis--two problems commonly shared by the pediatrician and the pediatric orthopedic surgeon. The importance of aggressive diagnostic measures and treatment for the septic hip is emphasized and the basis for the rationale is given. In the section on scoliosis, the reader is introduced to the "scoliometer," and a rationale for management of most of these children by the primary physician is given.

Adolescent↗