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Unrecognized hazards of surgical electrodes passed through metal suction-irrigation devices.

Surgical electrodes, passed through metal suction-irrigation devices, pose significant risks for unrecognized visceral burns through capacitively coupled current using monopolar electrosurgery. Plastic cannulas (and reducers) should be avoided with the metal suction-irrigation electrode; an all-metal trocar cannula confers limited safety. With surgeon education and advances in engineering, the potential for unrecognized visceral injury with capacitive coupling can be eliminated.

Burns↗

Rectal irrigation with short-chain fatty acids for distal ulcerative colitis. Preliminary report.

Colon cells from patients with ulcerative colitis utilize short-chain fatty acids inefficiently and may be exposed to decreased concentrations of these compounds. To test whether irrigation of the inflamed mucosa with short-chain fatty acids is useful, we conducted a six-week preliminary trial in 12 patients with distal colitis. Each patient used twice daily rectal irrigations with 100 ml of a solution containing acetate (80 mM), propionate (30 mM), and butyrate (40 mM). Two patients stopped at three weeks, one because of no improvement and the other because of complete resolution of symptoms. Of the 10 who completed the trial, nine were judged to be at least much improved and showed a change in a mean disease activity index score from 7.9 +/- 0.3 (SE) to 1.8 +/- 0.6 (SE) (P less than or equal to 0.002) and in a mucosal histology score from 7.7 +/- 0.7 (SE) to 2.6 +/- 0.7 (SE) (P less than or equal to 0.002). Thus, ulcerative colitis patients appear to benefit from increased contact with or higher than usual levels of these critical energy substrates.

Acetates↗

[Whole-gut irrigation for large bowel preparation in colorectal surgery (author's transl)].

In a controlled trial with 32 patients, whole-gut irrigation (wgi) was compared with elemental diet as a method of large-bowel preparation. Cleansing effect, caloric intake (bad taste of diet), and preparation time were significantly better in the first group (wgi). Since 1976, 203 patients have undergone wgi. Investigations concerning the effect of addition of antibiotics to the irrigant revealed optimum reduction of fecal flora with neomycin--bacitracin--clindamycin.

Clindamycin↗

Efficacy of steroid hormone in solution for intracranial irrigation during aneurysmal surgery for prevention of the vasospasm syndrome.

A series of 55 patients with ruptured cerebral aneurysms were treated with moderate removal of subarachnoid clot followed by intracranial irrigation with pH 8.0 Hartmann solution containing 1 mg/ml of methylpredonisolone sodium succinate after the aneurysmal clipping during early (before day 3) operation. Six (11%) of the 55 patients suffered vasospasm syndrome postoperatively. The clinical results are significantly better than a series of 68 patients operated on and treated before day 3 by intracranial irrigation with Hartmann solution (pH 8.0) only. The possible preventive effect of direct intracranial administration of steroid hormone is discussed.

Adult↗

Thermal injury of the colon due to colostomy irrigation.

A case of thermal burn and stricture of the colon following colostomy irrigation with hot water is described. The initial radiographic features on barium enema simulated nonspecific segmental colitis. Colonic stricture and enterolith formation developed subsequently. This case emphasizes that care should be taken in preparing irrigating and barium enema solutions.

Aged↗

Continuous irrigation-drainage of the subdural space for the treatment of chronic subdural haematoma. A prospective clinical trial.

Thirty seven adult patients which chronic subdural haematoma were randomized into two groups. Eighteen patients served as controls and underwent evacuation of the haematoma via burr holes and a gravity dependent closed-system drainage. Nineteen patients comprised the study group. These patients had a continuous irrigation-drainage system installed in an attempt to facilitate the removal of fibrinolytic substances present in the haematoma fluid and to try to reduce the rate of rebleeding from the haematoma membranes. No differences were found between the pre- and post-operative clinical status, haematoma volumes and the degree of CT changes between the two groups. The complication rate was similar in the two groups. One patient in the study group and three patients in the control group required an extended period of drainage (24-48 hours) prior to the removal of the drains. All patients improved following the procedures. Within 30 days post the initial evacuation of the chronic subdural haematoma, re-operation was required in only one patient in the study group as opposed to four of the controls. This difference was not however statistically significant. When the need for re-operation was combined with the need for extended drainage period, a significant difference was shown in favour of the study group. These results indicate that drainage combined with continuous irrigation of the subdural space does not affect the clinical outcome of the patients, but significantly reduces the frequency of inadequate drainage of the haematoma and prevents longer drainage periods and repeated operations.

Aged↗

Treatment of fecal impaction with pulsed irrigation enhanced evacuation.

PURPOSE: A new method of treating fecal impaction is described, selecting patients that would otherwise have required operative disimpaction. METHOD: Using the pulsed irrigation enhanced evacuation device, individuals were selected for treatment based on evidence of massive fecal impaction on physical examination or abdominal x-ray. RESULTS: Fourteen individuals were treated for fecal impaction. The patients ranged in age from 13 to 86 years. Only one patient required intravenous sedation, an elderly patient with Alzheimer's disease. The treatment was successful in each case, although repeated treatment was often necessary. No morbidity arose from the treatment. By the midpoint in our study, because of the success of this treatment, no patient required hospitalization for impaction. CONCLUSION: Pulsed irrigation enhanced evacuation has been in our experience a simple, quick, and effective treatment for severe fecal impaction.

Adolescent↗

Percutaneous decompression and irrigation for large bowel obstruction. New approach.

This investigation introduces percutaneous decompression and irrigation of the obstructed large bowel as a simple and safe procedure that can be undertaken for the emergency situation. This procedure was performed in 28 patients who presented with colonic obstruction caused by sigmoidal or rectosigmoidal carcinoma without any complications. It allowed patients to be properly prepared and investigated and then to receive definitive colonic surgery 36-48 hours after the decompression. Therefore, it is concluded that percutaneous decompression and irrigation can on one hand defer emergency surgery for colonic obstruction and on the other hand enable a one-stage definitive procedure to be undertaken during the same admission.

Adenocarcinoma↗

Dilutional hypocalcaemia from urological irrigating fluids.

A normal serum calcium concentration is essential for cardiovascular and muscular function. The hypocalcaemia-inducing potential of urological irrigating fluids was studied in 7 young men and in 10 prostatectomy patients. A total of 48 intravenous infusions of 1,000 ml of various irrigating fluids showed consistently that dilution of the serum calcium concentration occurs. The magnitude of the dilution was in between that recorded for albumin and for sodium. The free calcium concentration, however, correlated closely with the serum sodium level. These results suggest that dilutional hypocalcaemia can be expected to coexist with hyponatraemia in patients who develop the transurethral resection syndrome.

Adult↗

Prevention of colostomy in partial colonic obstruction by intraoperative rectal tube irrigation.

Four patients with partial obstruction of the colon, in whom adequate standard preparation for colonic resection was not possible, are presented. Clinically, these patients did not show sufficient signs of obstruction to require a preliminary colostomy. A technique of quarantining the area of tumor resection from the abdominal cavity is described, allowing for adequate preparation of the colon lumen at the site of anastomosis. After completion of the anastomosis, a large caliber (36 French) colonic tube is inserted, per rectum, through the anastomosis and the proximal colon irrigated with Betadine solution adequately emptying and sterilizing the lumen of the bowel to allow for primary anastomosis without a protective colostomy. The criteria for selection of patients for this technique are discussed. No complications, of significance, ensued. This method of intraoperative rectal tube irrigation, for prevention of colostomy in partial colonic obstruction, is safe when properly performed in the appropriate patient.

Adult↗

Intraoperative colonic irrigation with povidone iodine. An effective method of wound sepsis prevention.

In the ten-year period between 1975 and 1986, 367 patients underwent colonic resection with subsequent anastomosis using intraoperative colonic irrigation with 10 percent povidone iodine. One hundred thirty three patients underwent resection of the right or transverse colon, whereas 233 patients had left hemicolectomy with low anterior anastomosis or reanatomosis. Twenty individuals underwent emergency resection for perforation and temporary end colostomy. Nineteen of these patients returned for definitive reanastomosis as part of a two-stage procedure. The rate of wound infection, and/or intra-abdominal abscess formation was retrospectively reviewed and found to be completely nonexistent in these patients. This study examines the various techniques used to reduce the rate of wound infection after colonic surgery and addresses the concept of intraoperative povidone iodine irrigation.

Anastomosis, Surgical↗

Effect of water irrigations on human colonic mucosa structure after sigmoidostomy.

The colonic mucosa of patients with sigmoidostomies, who were operated on for rectal cancer, and treated thereafter for different periods of time with daily water irrigations to obtain complete evacuation, was investigated by histologic and histochemical methods. Microscopic examination of the test specimens showed that the epithelial continuity, the characteristic brush border, and the positive mucous reaction to PAS and Alcian blue-Alcian yellow methods were not significantly changed with respect to controls. In some test specimens a remarkable number of mitoses were evident in the crypts. Since this could result from water irrigation stimuli and/or might represent an early manifestation of a restored carcinogenetic process, specific investigations were performed on the 0-acylated sialic acids of the colonic mucins, which have been reported to represent markers of early malignant changes in colorectal epithelial cells. The results did not reveal alterations of the sialomucins in the treated specimens with respect to controls.

Aged↗

Intraoperative high-flow antegrade irrigation. A new bowel-cleansing system.

A new intraoperative method, employing a specially designed apparatus, is described by which the colon can be cleansed to a degree not obtainable by other methods. The method enables continuous antegrade irrigation with large volumes of irrigant at high rates of flow, prior to enterotomy. It has been tested in an experimental canine model and found to be safe and effective.

Animals↗

Dissolution of ureteral uric acid calculi with local litholytic irrigation.

This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral uric acid calculi. Fourteen cases of ureteral uric acid calculi were diagnosed by abdominal plain radiography (KUB), retrograde urography, ultrasonography (B-mode ultrasound), spiral computerized tomography(CT) and blood biochemical examinations. A ureteral catheter was passed retrogradely across ureteral calculi by cystoscopy. LLI with tromethamine-E (THAM-E) was performed via the ureteral catheter after the improvement of renal function and general situation and the control of urinary tract infection under the condition of intravenous application of antibiotics. The irrigation rate varied from 1000 to 1500 ml per day. Retrograde pyelography demonstrated complete dissolution of all the stones, 13 cases within 10 days and 1 within 12 days. Mild hematuria was observed in the majority of the cases and temporary aggravated lumbago in 1 case, with no other side effects. It is concluded that LLI is a practical and effective method in the treatment of ureteral uric acid calculi for its advantages of shorter duration,lower cost, less physical suffering and no severe complications.

Adult↗

[Accidental hypothermia: treatment of a case using peritoneal irrigation].

A case of accidental hypothermia is reported. This patient was rewarmed by using a peritoneal irrigation. Rewarming was rapid and without complication. The patient was discharged from the hospital free from any sequellae. Peritoneal irrigation constitutes a fast and effective technique of core body rewarming in cases of moderate or severe hypothermia. Another advantage of this method is that it can be accomplished without complicated equipment and that it can be used even in small community hospitals.

Aged↗

Oxygen embolism due to hydrogen peroxide irrigation during cervical spinal surgery.

Hydrogen peroxide is used to cleanse and irrigate wounds. As it decomposes immediately into water and oxygen on contact with organic tissue, it is usually regarded as a safe agent. We report a case of oxygen embolism associated with hydrogen peroxide irrigation of the surgical field during anterior fusion of the cervical vertebrae. It was accompanied by precipitous hypotension and decrease in pulse oximetry oxygen saturation and end-tidal CO2 tension. Semi-closed spaces formed under the apatite dowel and between the apatite dowel and vertebral bodies may have precipitated the absorption of oxygen bubbles into the vasculature. Although this case was associated with a rapid recovery and uneventful sequelae, it discourages the use of hydrogen peroxide in this procedure because of the potential hazards including cardiovascular collapse.

Carbon Dioxide↗

[Spinal epidural empyema. Limited surgical treatment combined with continuous irrigation and drainage].

Epidural empyema of the spinal column is a rare, but in some cases devastating, disease. Surgery can be excessive or very limited. We want to report our results of combined therapy of limited surgical treatment and continuous irrigation with antibiotic solution and drainage. In the last 5 years we have operated on 12 patients (7 female, 5 male, median age: 61.5 years, range: 22-89 years) with spinal epidural empyema. All surviving patients were evaluated after 3 months including MRI. Six infections were caused by injections, two by spontaneous discitis, two by chronic systemic infections, and in two patients the cause remained unknown. In every case we implanted two catheters, one for irrigation with antibiotic solution and one for drainage. On average the catheters were used for 3 days. For evacuation in seven patients interlaminar fenestration in one, two, or three levels was enough. Only in one patient was a laminectomy performed. Five patients recovered totally, three partially, one did not recover at all, and three died. The autopsy of two dead patients showed complete healing of the operated area; they died because of lethal infections in other parts of their body. In only one case did a reoperation have to be done. The cause was an additional subdural empyema. In spite of the limited surgical procedure without relevant operative morbidity the reported method is an effective and safe therapy.

Adult↗

The effects of different intraocular irrigating solutions on the apoptosis of cultured RPE cells.

PURPOSE: To investigate the effect on porcine retinal pigment epithelial (RPE) cells of modified intraocular irrigating solutions compared with BSS and BSS plus. METHODS: Confluent cultures of RPE cells were incubated in experimental intraocular irrigating solutions. The cells were then examined for breakdown of DNA by the TUNEL procedure. Fragmentation of the DNA from cells was also confirmed by flow cytometry. RESULTS: Most of the experimentally, treated cells exhibited a shrunken appearance for up to 72 h. There was a steady increase in the number of cells labeled by the TUNEL method in three solutions with time. The data demonstrated that the influence of solutions on the percentage of RPE cell nuclei that gave a clear positive TUNEL stain was, in ascending order: modified solution>BSS>BSS plus. Of the three solutions tested, BSS plus showed least apoptosis. CONCLUSIONS: It is suggested that BSS plus is less harmful to RPE cells than the other solutions tested. Introduction of other adjunctive solutions of antibiotics, mydriatics, miotics, and steroid, resulting in an altered electrolyte balance, pH, or osmolality in the solution, may compromise the safety and efficacy of a properly formulated and packaged solution.

Acetates↗