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At least 1,351 records · Page 75Linked to original sources
PubMed1987

[Nutritional behavior of non-insulin-dependent type II diabetes patients using the KALI 2.1.2 computer program].

Forty patients with non-insulin-dependent diabetes mellitus (NIDDM) were investigated regarding their individual diet history, including dietary pattern and dietary habits. The energy intake in men was 2,180 +/- 460 kcal/day. The carbohydrate content was 192 +/- 57 g/day (38 +/- 7%), protein 93 +/- 20 g/day (19 +/- 3%) and fat 96 +/- 26 g/day (43 +/- 7%). Nutritional intake of saturated fatty acids was 37 +/- 11 g/day, whereas the intake of polyenic acid was 14 +/- 5 g/day. Thus the p/s-quotient was 0.4 +/- 0.1. The cholesterol intake amounted to 396 +/- 165 mg/day. The dietary fibre content was 33 +/- 21 g/day. The caloric intake of women was 1,800 kcal/day. The daily amount of carbohydrate was 154 +/- 46 g/day (37 +/- 6%), of protein 82 +/- 21 g/day (20 +/- 4%), of fat 82 +/- 32 g/day (43 +/- 6%). Saturated fatty acids were 33 +/- 14 g/day, polyenic acid 11 +/- 5 g/day, the p/s-quotient 0.4 +/- 0.2. The cholesterol intake was calculated to be 341 +/- 118 mg/day. The supply of electrolytes, trace elements and vitamins was often marginal. We found that usually practiced diabetes diet is too fatty, rich in cholesterol and poor in carbohydrate and fibre. As a result of the high amount of fat, which comprises 43% of the total calories and the low p/s-quotient of 0.4, the diet must be considered atherogenic.

Blood Pressure↗
PubMed1986

[Nutritional behavior of insulin-dependent diabetes patients studied with the KALI 2.1.2 computer program].

We investigated the levels of intake of essential nutrients in 51 patients with insulin dependent diabetes mellitus. The mean daily intake in males was 223 +/- 55 g carbohydrates, 111 +/- 22 g fat and 112 +/- 27 g protein. In females the mean daily intake was 166 +/- 36 g carbohydrates, 78 +/- 23 g fat and 97 +/- 25 g protein. the percentage of calories from carbohydrates, fat and protein was for males 36:40:18 and for females 37:39:21 respectively. The daily intake of dietary fiber was 32.5 +/- 8.0 g in men and 28.3 +/- 6.4 g in women. The mean linoleic acid intake was 12 +/- 5 g/day in men and 9 +/- 4 g in women. A marginal deficiency of linoleic acid was found in 15% of men and in 25% of women. The P/S ratio of the diet was 0.35. The consumption of vitamins, minerals and trace elements differed considerably from the recommended dietary allowances.

Adult↗
PubMed2002

[Scientific evaluation and quality assurance in refractive surgical interventions. Evaluation of the Datagraph med computer program].

BACKGROUND: During recent years refractive surgical procedures have been increasingly used to correct refractive errors. Exact saving and assessment of pre-, intra- and postoperative results for scientific evaluation are desired and are necessary for quality management. The purpose of this investigation was to evaluate the database program Datagraph med (version 2.5) which has been developed for data processing and assessment in refractive surgery. MATERIAL AND METHODS: Pre-, intra- and postoperative data of 169 eyes treated with different refractive surgical methods (laser in situ keratomileusis, photorefractive keratectomy, laser thermal keratoplasty, phacic IOL) were collected, entered in the database and then evaluated by the above-mentioned program (with a follow-up of up to 12 months). The exactness of the Datagraph results was compared by means of manual recalculation. RESULTS: Datagraph med was able to precisely process the patient data and save them in a database. Statistics and graphs presented by Datagraph were as data has been entered. Furthermore all standard graphs requested by the international consensus for evaluation of refractive surgical data (stability, predictability, efficacy, safety and complications) could be imaged. CONCLUSIONS: Datagraph med is a helpful and precisely functioning program for processing and evaluation of refractive surgical data. It can be used for both scientific studies and for quality control. A continuous development and improvement of the program as well as the addition of statistical functions will be necessary due to the on-going progress in refractive surgery.

Adult↗
PubMed1989

A computer program for analyses of vital statistics-based occupational mortality data.

Routinely collected vital statistics mortality data (death certificate data) on occupation and industry are useful for (1) generating hypotheses about potential occupational hazards and (2) identifying occupational mortality differentials possibly associated with socioeconomic and life-style factors. This paper presents a Fortran program that analyzes occupational mortality using vital statistics and census data. The user can form any desired grouping of age, race, occupation (or industry), and cause of death codes for analysis. The program also allows stratification on social class or other user-defined correlates of occupation such as smoking behavior. Furthermore, program output can be used for Poisson regression analysis of mortality rates.

California↗
PubMed1988

A computer program to calculate mean skin temperature from measurements available from field trials.

Attempts to estimate mean skin temperature for subjects during prolonged experiments in field conditions are often made difficult because probes become disconnected or cease to function. There are several equations which allow estimation of mean skin temperature from a reduced number of functioning probes. The Fortran program described chooses the appropriate equation, calculates the mean skin temperature using whichever readings are available from the six selected sites and calculates mean body temperature using also rectal temperature. The organization of the program is such that it could easily be modified for use on results from a wide range of experimental conditions.

Electronic Data Processing↗
PubMed1993

A computer program in QuickBasic for the selection of tests for the identification of Helicobacter pylori.

Reliable microbiological tests are needed for the identification of bacteria. A program has been written in QuickBasic to identify such tests by using a formula that is based on Gyllenberg's Sum of C(i) and Gyllenberg's Rank R(i). A total of 139 papers on a newly isolated bacterium, Helicobacter pylori, was used as data source for the coding of test results into an input file. The program outputs a list that aids in the determination of suitable tests for the identification of H. pylori. These tests chosen by the formula were found to be correctly identified as supported by later publications on the bacterium.

Decision Support Techniques↗
PubMed1987

Exponential model for a regulatory enzyme. Computer program for the determination of the model constants from initial velocity data.

The paper describes a program (DESCENT) which evaluates the constants of the exponential model for a regulatory enzyme with up to four substrates or up to three substrates and one effector. The program operates by repetitive adjustment of the model constants so as to secure a better fit between the observed and calculated initial velocities of reaction. At each adjustment, all the constants are incremented simultaneously by amounts determined by a steepest descent criterion. The program is tested by artificial data with and without added error and it is shown that good estimates of the constants can be recovered.

Allosteric Regulation↗
PubMed1992

A statistical model and computer program to estimate association constants for the binding of fluorescent-labelled monoclonal antibodies to cell surface antigens and to interpret shifts in flow cytometry data resulting from alterations in gene expression.

Flow cytometry is used to obtain estimates for the distribution of fluorescent ligands bound to cell surface receptors throughout a cell sample. The equipment used provides light scattering parameters and also cell staining data in the form of dot plots and histograms of fluorescence intensities and the frequency of occurrence of particular fluorescence intensities. It is then assumed that fluorescence intensity is proportional to the number of labelled ligands bound to surface receptors. In this paper we present an outline of a statistical theory to account for the stretching and translation of such flow cytometry profiles which occur either as a result of alterations in gene expression, or from changing the sub-saturating concentration of fluorescent-labelled monoclonal antibodies or lectins used to stain the cells. We describe how the theory has been incorporated into two programs CSAFIT (cell surface antigen fit) and MAKCSA (make data to test CSAFIT). The program CSAFIT can be used to estimate two parameters, alpha and beta, by constrained non-linear regression analysis of the flow cytometry profiles. If the shift results from changes in the concentration of a staining agent then the estimates alpha and beta calculated by CSAFIT are functions of the ligand concentration, the ligand type and the cell line characteristics. They quantify the stretch and translation events that are encountered in flow cytometry. So when the parameter estimates alpha and beta are then further analysed as functions of ligand concentration, estimates for the average association constant K for the binding-site/ligand interaction can be obtained. This paper describes details of the development of programs CSAFIT and MAKCSA. We also discuss the distribution of parameter estimates calculated by CSAFIT and the overall performance of CSAFIT as assessed by simulation studies using data generated by MAKCSA.

Antibodies, Monoclonal↗
PubMed1990

SBR: a computer program to record and analyse sexual behavior in rodents.

SBR (Sexual Behavior Recorder) is a program designed to record and analyse data from research on the sexual behavior of rats and other animals with similar patterns of sexual behavior. SBR allows the user to record the characteristic events of both the male and female's sexual behavior: mounts, intromissions, ejaculations and lordosis. It also allows the user to record two other types of events, and analyse them in terms of frequency and duration, using two user-defined keys. The program allows the correction of any event erroneously recorded. SBR can simultaneously control observations made by one or two observers, and on one or two experiment boxes. In the case that two observers record from the same experiment box, the program calculates a set of measures of reliability between the observers. At the end of each observation, SBR conducts a descriptive analysis of the recorded events, including the parameters normally used in scientific literature on the subject, and writes this analysis to disk files. As well as the default calculation parameters, it is possible to calculate any other, or to use the program as a record of general purpose events using the file which contains all the recorded events in sequential order and the exact time at which they were recorded. SBR was written using the compiler Turbobasic 1.1 from Borland International Inc. (1987).

Animals↗
PubMed1990

Development of a computer program classifying rat sleep stages.

We developed a simple and precise program for the on-line judgement of the sleep stages of four rats simultaneously for an unlimited period, using a commercially available general purpose signal processor (NEC-Sanei 7T17; 32-bit, 5 MHz, 4 Mbyte, 1 Mbyte 1 floppy disc drive). EEG and EMG were recorded with an 8-channel polygraph (NEC-Sanei, System 380) through electrodes chronically implanted into the brain. The signals were A/D converted every ms and integrated for 2760 ms after full-wave rectification, and the subsequent 2240 ms was used for calculation and further analysis. All data were handled with this 5000 ms as the minimum unit. Then 3 sleep stages, i.e., waking, slow-wave sleep, and REM sleep, were determined by a template matching method from the relative amplitudes and durations of the integrated EEG, EMG and EMG surge data based on algorithms of standard visual amplitude analysis criteria for the sleep-stage classification. An agreement matrix was constructed between the data scored by the visual and by the automatic analysis, and the agreement value was satisfactory, although slight variability was seen in the REM sleep-stage determination. This result indicated that EEG and EMG data analysis is appropriate for researching the circadian rhythmic mechanism of the sleep-wake cycle.

Animals↗