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At least 1,351 records · Page 75Linked to original sources
PubMed1998

[The clinical significance of biological characters on non-small cell lung cancer].

OBJECTIVE: To study the biological characters of 137 cases of surgically treated NSCLC and their correlation with stages, types and survival rates. METHOD: Electronmicroscopy, immunohistochemistry and FCM were employed in this prospective, randomized study. K-P curve, COX univariance and multivariance were used for statistic analysis. RESULTS: (1) Electronmicroscopy showed that 40% of squamous cancer and 40% of adenocarcinoma diagnosed microscopically were mixed type. (2) The positive rate of p53 expression increased in advanced stage of NSCLC, and the survival rate was lower in cases with positive p53 expression. (3) A higher survival rate was seen in cases with positive Hras expression. (4) Lower survival rates were seen in cases with abnormal DI and PI. (5) Miscellaneous: expression rates of c-erbB2 and PCNA were related to adenocarcinoma and mixed type electronmicroscopically confirmed respectively. CONCLUSION: From this study p53, Hras, DI, PI, c-erbB2 and PCNA were found related to stages, types and survival rates, respectively.

Adenocarcinoma↗
PubMed1998

[Effect of kidney yin-yang replenishing Chinese herbs on the binding character of insulin receptor on hepatocyte membrane in androgen-induced sterility rats].

OBJECTIVE: To observe the effect of Kidney Yin-Yang replenishing Chinese herbs on the binding character of insulin receptor (IR) on hepatocyte membrane from androgen-induced sterility rats (ASR). METHODS: The number and affinity of IR on hepatocyte membrane of ASR were determined with radioligand binding assay. RESULTS: There was no significant difference of the number or affinity for both high and low affinity sites of IR between normal and ASR. CONCLUSION: The treatment with Kidney Yin-Yang replenishing Chinese herbs had no effect on insulin binding although a relatively high rate of ovulation induction on ASR was observed.

Animals↗
PubMed1992

The effects of microgravity on the character of progeny of Drosophila melanogaster.

To study how the microgravitational environment influences the character of the progeny of Drosophila melanogaster, the S1 insects produced during the 8-days of space flight were self-bred for four generations. Higher variational rate was found in S2. After removing the variant flies, the variational rate of the remaining Drosophila progeny decreased generation by generation. There was no notable sex-linked recessive lethal mutation of parent flies and no gene mutation found in their test-cross examination. It indicates that the germ-cell of parent adult flies were not much influenced by microgravity, but the embryo of filial generation bred in space were greatly influenced by microgravity. Therefore, the mutagenesis during the embryogenic development should be taken into account in the bio-breeding under the space microgravitational environment.

Animals↗
PubMedDate not supplied

[Hereditary thrombocytopathic thrombocytopenia. Report of 2 cases transmitted with dominant character].

Hereditary thrombocytopathic thrombocytopenia is reported in a family (mother and son) and is transmitted with dominant character of moderate to severe intensity (platelets fluctuated from less than 5,000 per mm-3 to 20,000 with sporadic higher rises), normal survivorhship, larger than normal diameter and abnormal platelet 3 factor. Comments are made on its resemblance to idiopathic thrombocytopenic purpura and stress is placed on the importance of its identification through the decision of splenectomy with negative results in these patients.

Autopsy↗
PubMed2000

[Relationship between light and regeneration character of Huangshan pine].

The growth and physiological characters of 1-3 years old Huangshan pine seedlings in pure and mixture plots with four different transparancy were determined, and the germination percentage of seeds and their complex stressing vigour were tested. Meanwhile, the regeneration mechanism of Huangshan pine in natural forest was studied in this paper. The results showed that the plumpness of seeds was 65%, the germination percentage was 27%, and the complex stressing vigour was 26%. The lower germination percentage affected the reproduction of Huangshan pine. The photosynthetic rate was more affected by solar energy, but less by humidity and surface temperature. With high light composation, Huangshan pine's regeneration under forest was difficult. The seedlings of Huangshan pine in mixed coniferous and broadleave tree plots were at a disadvantage because of slow growth and insufficient light.

Ecosystem↗
PubMed2000

[Wind tunnel experiment on canopy structural parameters of isolated tree and wind velocity field characters nearby].

The canopy structural parameters(porosity beta and permeability alpha) of isolated tree, and the wind velocity field character nearby were analyzed by wind tunnel experiment. The results show that alpha and beta fitted the function of alpha = beta 0.6, and the wind velocity nearby decreased in ellipsoid contour. The contour increased with increasing tree height and canopy width, and decreased with increasing permeability (or porosity). The isotach became the shape of ellipses or elliptic segments in horizontal and vertical plans.

Trees↗
PubMedDate not supplied

[The closed head injury syndrome--frequency and character of brain parenchyma lesions].

The aim of this investigation was to determine the frequency and character of the brain parenchyma lesions using CT scan and MR in patients with closed head injury, and afterwards to establish the connection of those changes with clinical parameters (neurological deficit and the degree of consciousness disorder), evaluating the sensitivity and specificity of neuroradiological procedures. The investigation comprised 40 patients with closed head injury. Grade of neurological deficit (Canadian Neurological Scale) and the degree of consciousness disorder (Glasgow Coma Scale) were determined in all patients by the same neurologist. The results revealed significantly higher specificity and sensitivity of brain examination using MR in patients with closed head injury, particularly in the detection of small ischemic and contusion lesions. Likewise, the correlation of positive findings using MR was more significant concerning the grade of neurological deficit and the degree of consciousness disorder compared to the brain examination using CT scan.

Adult↗
PubMed2000

Comparative study on characters and outcomes of patients injured from traffic accidents in different rank hospitals.

OBJECTIVE: To compare the characters and outcome s of patients injured from traffic accidents in different rank hospitals. METHODS: From 8 hospitals of ranks I-III, 1915 cases were sa mpled and divided into 4 groups. Injuries of all patients were accessed by the method of RTS, AIS-ISS-AP and ASCOT. RESULTS: (1) The higher rank of hospitals, the severer the pati ents' condition were. Mean ISSs in hospital ranks II and III were greater tha n 16, which were recommended as a standard of severe trauma. (2) Transportation of se vere patients to high level hospitals prolonged the pre-hospital duration by 5 -9 h. (3) Factors contributing to death were the trauma severity, complications, hospital ranks that reflect the quality of the medical care. CONCLUSIONS: (1) This sample of 1915 cases matches the condit ion of most Chinese hospitals in characteristics of traffic trauma patients. (2 ) Most Chinese hospitals can be divided into 3 degree of trauma center by a crite ria of ISS and the unexpected death. (3) Incidence of multiple injuries shows no significant difference in each rank of hospitals. (4) The relationship between the hospital rank and the quality of trauma care is significant. We suggest tha t a RTS=11 or ISS=9 be triaged to trauma center, and a 10% Ps (survival pr obability) less than the average Ps of a hospital be triage to higher level hosp itals.

Journal Article↗
PubMed1999

[Comparative study of the character of cefazolin pharmacokinetics between Neijiang pig and human].

OBJECTIVE: To study the character of cefazolin (CEZ) pharmacokinetics on Neijiang pig and human. METHODS: The serum concentration of CEZ in 8 normal Chinese adult men, 9 of 8-month male Neijiang pigs and 5 of 4-month male Neijiang pigs were detected by high-performance liquid chromatography (HPLC). RESULTS: The pharmacokinetic parameters suggested that two-compartment model was found in all groups after intramuscular injection of CEZ. In normal men, 8-month pigs and 4-month pigs, the peak time (Tmax) was (58.8 +/- 13.0), (19.7 +/- 9.9) and (18.2 +/- 8.6) min respectively, T1/2 alpha was (42.3 +/- 19.7), (19.0 +/- 7.7) and (9.3 +/- 1.9) min, the peak concentration (Cmax) was (101.6 +/- 14.6), (28.7 +/- 9.0) and (23.5 +/- 4.6) mg/L; Vd was (0.096 +/- 0.016), (0.374 +/- 0.184) and (0.386 +/- 0.211) L/kg; T1/2ka was (22.5 +/- 6.8), (8.6 +/- 4.8) and (10.6 +/- 10.2) min; T1/2 beta was (117.3 +/- 8.6), (84.2 +/- 9.8) and (45.1 +/- 11.5) min; clean rate of plasma Cl was (0.8 +/- 0.1), (6.8 +/- 1.2) and (11.0 +/- 3.0) ml/kg.min; AUC was (21,803 +/- 4,145), (2,407 +/- 443) and (1,636 +/- 685) mg.min/L. CONCLUSION: It could conclude that the Neijiang pigs could eliminate CEZ effectively, but the absorption, distribution and elimination of CEZ in pigs were quicker than that of in human while the absorption from muscle in both pig groups were lower than that in human.

Adult↗
PubMed1975

[The role of neuromediators in changes in the character of respiration and in its correction following cranio-cerebral trauma].

Experimental studies on dogs and clinical examinations of patients with brain injuries permitted to state that the activity of the sympathicoadrenal system in the posttraumatic period is increased. The cholinergic processes in such conditions are inhibited, the concentration of blood serotonin is decreased. Depending upon the character of changed neurohumoral blood factors the parameters of external respiration (hypotachypnoe with respiratory acidosis) are also changed. In such condition hydrocortison fulfills the normalizing effect on the respiratory function only in a stimulation of the inhibited cholinergic system by cholinomimetics.

Acetylcholine↗
PubMed1983

[The population and character of traditional communities in insular Southeast Asia].

"This article discusses the character of population distribution and its relation to the structure of societies and states in Insular Southeast Asia in the early and mid nineteenth century. Except in Java and Bali, populations were characterized by sparsity, diversity, smallness, and mutual independence. Despite the effects of crisis mortality, the long-term population growth in the traditional period seems not to have been much different from [that] in India and China, which suggests the smallness of the original or early populations." The author notes that new communities were formed by the separation of settlements in frontier regions and that these patterns continued into the middle of the nineteenth century. The traditional order seems to have broken down in the late nineteenth century as a result of the combined pressures of colonialism and population increase. (summary in ENG)

Asia↗
PubMed1975

[Character of neuronal functional associations according to the content of RNA and SH-groups in the cat cerebral cortex].

A new principle of taxonomy was used for determination of the spaceal character of the neuron cortex associations based on RNA and SH-group contents. The experiments were performed on the intact cat's somatosensory cortex, and after epileptiform activity induced by electrical stimulation. In the intact cortex, the neuronal mosaic of metabolic activity (determined by RNA and SH-group contents) was meshed, whereas in the hemisphere with epileptiform activity this mosaic was formed by less numerous but larger groups of cells. The functional significance of these groups is discussed.

Animals↗
PubMedDate not supplied

The autistic character.

The purpose of this paper is to introduce the autistic character as a diagnostic entity and then delineate the formative early object relations, the symptoms and how they develop out of the early object relations, and the related defensive behavior. The paper will end with recommendations for treatment.

Affect↗
PubMed2002

[Physical and chemical characters of materials from several mineral aerosol sources in China].

Loess, sand and coal-ash samples were collected at several mineral aerosol sources to analyze the particle size as well as the major and trace elements. The results show that the physical and chemical characters were quite different between these samples. The loess was mainly made up of small particle size that 91% of the sample could be transported as mineral aerosol to a long distance. The sand consists of relative large-size particles, with only 15% sample being formed into mineral aerosol. The coal-ash samples were quite different in particle sizes in the two regions, with 39% of particles < 74 microns in Fushun samples while only 7% in Huhehaote samples. Chemical compositions varied significantly in different particle sizes, with trace elements obviously enriched in the least size. The elements to Al ratios (E/Al) were quite alike between the Loess and the sand, but very different from the coal ash. The similarity of the E/Al ratios between the Loess, the sand and the deep-sea clay suggest that the deserts and the Loess in the northwest China may be important sources for sediment of the northwest Pacific Ocean.

Aerosols↗
PubMed2002

A modern optical character recognition system in a real world clinical setting: some accuracy and feasibility observations.

Advances in optical character recognition (OCR) software and computer hardware have stimulated a reevaluation of the technology and its ability to capture structured clinical data from preexisting paper forms. In our pilot evaluation, we measured the accuracy and feasibility of capturing vitals data from a pediatric encounter form that has been in use for over twenty years. We found that the software had a digit recognition rate of 92.4% (95% confidence interval: 91.6 to 93.2) overall. More importantly, this system was approximately three times as fast as our existing method of data entry. These preliminary results suggest that with further refinements in the approach and additional development, we may be able to incorporate OCR as another method for capturing structured clinical data.

Electronic Data Processing↗
PubMed2002

Physiological characters of Sporothrix schenckii isolates.

Sporotrichosis is endemic in three regions (east, north and south) in India. The colony morphology and physiological characteristics of 49 clinical isolates from these three regions (25 from north India, 17 from east India and seven from south India) were analysed in both mycelial and yeast forms. No difference in colony character was seen among the 49 isolates on three different media. Growth of all isolates was inhibited at 40 degrees C. The yeast forms were found to be more tolerant to osmotic pressure and salt concentrations. Most mycelial forms grew well between pH 3-12.0 whereas most yeast forms could tolerate a pH range of 2.4 to 9.5. Variations in assimilation of arabinose, dextrin, raffinose, rhamnose and starch was observed among strains from different geographical regions. The yeast forms did not show any urease activity but the mycelial forms of all isolates could split urea. Phenol oxidase and potassium nitrate assimilation were positive and gelatinase activity and casein hydrolysis were negative for all isolates.

Carbohydrate Metabolism↗
PubMed1976

[The effect of several neurotropic preparations on the differential character of pancreatic enzyme secretion].

Chronic experiments were conducted on dogs with pancreatic fistulae; secretion of the pancreas (basal and stimulated by duodenal perfusion by acid solutions, albumin and its polypeptide hydrolysate) was investigated with consideration to its enzyme (amylase, trypsin, chymotrypsin) secretion. The polypeptide hydrolysate proved to stimulate the pancreatic enzymes more than pure protein. Barbamyl, chlorpromazine and amyzyl inhibited both the basal and the stimulated secretion of the pancreas. The differential character of the pancreatic enzyme secretion was most disturbed by chlorpromazine and amizyl; this served as an evidence of the substantial role of the central adrenergic and cholinergic structures in the adaptation of the pancreatic secretion to food stimuli.

Amobarbital↗
PubMed1999

[Biological characters of adenoid cystic carcinoma cells transduced with HSV-tk gene].

OBJECTIVE: To study the effects of herpes simplex virus thymidine kinase(HSV-tk) gene transduction on adenoid cystic carcinoma(ACC) cells. METHODS: Gene transduced cells were detected with growth rate, scanning electronic microscope, transmission electronic microscope, cell cycle analysis and the expression of major histocompatibility complex(MHC) class I or II molecules. RESULTS: The parameters detected in gene transduced cells and parental tumor cells were similar. CONCLUSION: The HSV-tk gene transduction would not change the biological characters of tumor cells greatly.

Carcinoma, Adenoid Cystic↗