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Coronary angiography observations: evidence-based or ritualistic practice?

OBJECTIVE: The purposes of this study were to describe the incidence and occurrence of femoral artery bleeding during the first 6 hours after coronary angiography and to determine whether there is a relationship between current postangiogram observation protocols and the detection of complications. DESIGN: This was a prospective descriptive study. SETTING: The study was conducted in 3 university hospitals in Melbourne, Australia. PATIENTS: Subjects included 55 patients representing the complication rate of 1075 patients, mean age 61 years (SD, 12), 69% male. RESULTS: About 5.1% of patients had 1 or more incidents of bleeding requiring manual compression. In 4.2% of patients, bleeding occurred within 6 hours of angiography. Bleeding occurred a median of 2.02 hours (Q1 = 45 minutes, Q3 = 4.31 hours) after angiography. Patients without pressure bandaging bled a median of 1.32 hours (Q1 = 36.50 minutes, Q3 = 2.59 hours) after angiography. Patients with pressure bandaging bled a median of 4.75 hours (Q1 = 2.25 hours, Q3 = 7.28 hours) after angiography. In 40.6% of cases, bleeding was detected through the patient's call for assistance, and in 59.4% of cases nurses noted bleeding while checking the puncture site. Postcatheter observations were recorded 23.70 (SD, 14.60) minutes before the bleeding incident. There were no significant changes in vital signs, systolic blood pressure (P >.05), diastolic blood pressure (P >.05), or pulse (P >.05) before or during a bleeding episode. All were within normal parameters. No neurovascular assessment anomalies were detected. CONCLUSION: The use of pressure bandaging has a significant effect on the incidence and pattern of bleeding. Routine vital sign measurement has no relevance in detecting local complications after angiography. The most significant complication is bleeding that requires manual compression. Detection is through frequent puncture site observation and patient recognition and communication.

Aged↗

Compression and walking versus bed rest in the treatment of proximal deep venous thrombosis with low molecular weight heparin.

OBJECTIVE: The purpose of this randomized controlled trial was to evaluate the benefits of compression and walking exercises in comparison with bed rest in the acute stage of proximal deep venous thrombosis (DVT). METHODS: Forty-five patients with proximal DVT that was proved with compression ultrasound scan or phlebography were randomized into three groups. Group A consisted of 15 patients who received inelastic compression bandages (Unna boots on the lower leg, adhesive bandages on the thigh), and group B consisted of 15 patients who received thigh-length compression stockings, class II. Group C consisted of 15 patients who underwent bed rest and no compression. All patients received dalteparin, 200 IU/kg per body weight, subcutaneously every 24 hours. The clinical characteristics of the three groups were comparable. Primary end points were the reduction of pain assessed daily with the Visual Analogue Scale and the Lowenberg test, the reduction of leg circumference at the ankle and calf levels, and the improvement of clinical scores. The daily walking distance was measured with a pedometer. Safety parameters were ventilation-perfusion scans and duplex ultrasound scans performed on days 0 and 9. RESULTS: The daily walking distance was between 600 and 12,000 m in the compression groups and averaged 66 m in the bed rest group. The pain level showed a statistically significant reduction starting after the second day in the compression groups (A and B) and after 9 days in the bed rest group C (P <.05). The same was true for the measurement of leg circumference. Improvement of the clinical scores was significantly better in the compression groups compared with the bed rest group (P <.01). There was no significant difference concerning the occurrence of new pulmonary emboli and regression of thrombus diameter. Progression of thrombi in the femoral vein was greater and occurred more frequently in the bed rest group than in the other two groups (P = not significant). CONCLUSION: Mobile patients with acute proximal DVT treated with low molecular weight heparin should be encouraged to walk with compression bandages or medical compression stockings. The rate of resolution of pain and swelling is significantly faster when the patient ambulates with compression. The risk of pulmonary embolism is not significantly increased by this approach.

Acute Disease↗

Does thigh compression improve venous hemodynamics in chronic venous insufficiency?

OBJECTIVE: The aim of this study was to investigate the hemodynamic effects of thigh compression in patients with deep venous incompetence. PATIENTS AND METHODS: This diagnostic test study was set in a municipal general hospital. Twelve patients with venous leg ulcers (CEAP classification, C6 Es Ad Pr; four men and eight women), with a mean age of 56.5 +/- 16.8 years, with popliteal venous reflux of more than 1 second detected with duplex scan, underwent investigation with the following methods: 1, the pressure exerted under thigh-length compression stockings class II and short-stretch adhesive compression bandages was measured with an MST tester (Salzmann, Switzerland) and a CCS 1000 device (Juzo, Germany), respectively; 2, the great saphenous vein and the femoral vein on the thigh were compressed with a pneumatic cuff (0, 20, 40, and 60 mm Hg) containing a window through which the diameters of these veins could be measured with duplex ultrasonography; and 3, with the same thigh-cuff occlusion procedure, the venous filling index (VFI) for each experiment was measured with air plethysmography. These values reflected the presence and extent of venous reflux in each experiment depending on the degree of venous narrowing. RESULTS: The mean pressure of a class II compression stocking was about 15 mm Hg at the thigh level, and adhesive bandages achieved a pressure of more than 40 mm Hg in the same location. A statistically significant reduction of the diameters of the great saphenous vein and the femoral vein could be obtained only when the cuff pressure on the thigh was equal to or higher than 40 mm Hg (P <.001). A reduction of the venous reflux (VFI) was achieved only with a thigh pressure of 60 mm Hg (P <.001). No significant reduction was seen of VFI with a thigh pressure in the range of the class II stockings. Previous investigations have shown that, in patients with deep venous incompetence, a pressure cuff on the thigh with 60 to 80 mm Hg is able to reduce ambulatory venous hypertension. CONCLUSION: Thigh compression as exerted with class II thigh-length compression stockings is not able to significantly reduce venous diameter or venous reflux. However, with a pressure of 40 to 60 mm Hg on the thigh that can be achieved with strongly applied short-stretch bandages, considerable hemodynamic improvement, including reduced venous reflux, can be obtained in patients with severe stages of chronic venous insufficiency from deep vein incompetence. The practical value of these preliminary findings should be investigated with further clinical trials.

Bandages↗

Visible markers of brain injury influence attributions for adolescents' behaviour.

PRIMARY OBJECTIVE: Experiments investigated whether attributions for a brain-injured person's behaviours were affected by markers of injury. People misattribute behaviours that result from brain injury to personality or life stages (e.g. adolescence), particularly when there are no visible markers of the injury. RESEARCH DESIGN: Scenarios presented a photograph of an adolescent boy, who either wore or did not wear a head bandage. The boy was described as suffering a brain injury and showing four changes in his behaviour, relating to sleep, anger, self-confidence and motivation. METHODS AND PROCEDURES: For each behaviour, students (n=100) rated attributions to the brain injury and adolescence. OUTCOMES AND RESULTS: When there was no bandage, participants attributed the behaviours to adolescence more than brain injury, whereas with the head bandage they invoked both causes equally. CONCLUSIONS: When actions resulting from brain injury are attributed to causes other than the injury, this misattribution hinders accurate diagnosis and treatment. Data on effects of injury and individual levels of pre-morbid behaviours lead to accurate attributions.

Adolescent↗

A pilot leg ulcer clinic in a geriatric day hospital.

Twenty-six patients with leg ulcers with a mean age of 80 years were assessed at a day hospital to determine the aetiology and to carry out a trial of four-layer compression bandaging for those suitable. Ten had ankle brachial pressure indices (ABIs) < 0.8. Of nine patients with venous disease who received compression bandaging, only two ulcers healed and have remained healed with fitted below-knee elastic stockings. The remaining patients were unable to tolerate compression or developed deterioration of their ulcers. Nine patients had unhealing arterial ulcers all unsuitable for reconstructive surgery. Five patients presented with pressure sores due to bandages, shoes or heel pressure in bed. All healed slowly with leg elevation and pressure relief. Four patients had extensive non-venous, non-arterial ulceration associated with fluid retention and dependent oedema exacerbated by spending their nights in chairs. Varicose eczema was healed in 12 patients. All the patients had multiple pathology and poorly controlled pain. Although complete healing was achieved in only six patients, the importance of ABI measurement and the gross mixed pathology suggests that every elderly patient with a leg ulcer needs medical assessment and management and that this could form a valuable service of a geriatric day hospital.

Aged↗

Sutureless gingival grafting. A simplified procedure.

Suturing a gingival graft is often the most time-consuming stage of the grafting procedure, especially in regions of difficult access. Previously, it has been suggested that a combination of adhesive cellophane and cyanoacrylate may be used to immobilize the graft without suturing. The technique presented here attempts to simplify further sutureless grafting with the following modifications: - Bandage tape is used instead of adhesive cellophane. - The tape is not placed on the teeth but on the attached gingiva on either side of the graft site. - The use of cyanoacrylate is discarded. The success of the procedure depends on complete haemostasis as any moisture will prevent the tape from adhering to the gingiva. Inherent advantages of sutureless grafting accomplished with the use of bandage tape are: - The graft lies flat on the recipient site and is kept under slight pressure by the tape. - Minimal blood clot is present between the graft and the recipient site. - The "wick" effect of the sutures is eliminated. - The chairside time is greatly reduced. - A shorter appointment and no sutures to remove imply less discomfort for the patient. The technique is contraindicated should the patient present an allergic background to bandage tape.

Bandages↗

Cost effectiveness of community leg ulcer clinics: randomised controlled trial.

OBJECTIVES: To establish the relative cost effectiveness of community leg ulcer clinics that use four layer compression bandaging versus usual care provided by district nurses. DESIGN: Randomised controlled trial with 1 year of follow up. SETTING: Eight community based research clinics in four trusts in Trent. SUBJECTS: 233 patients with venous leg ulcers allocated at random to intervention (120) or control (113) group. INTERVENTIONS: Weekly treatment with four layer bandaging in a leg ulcer clinic (clinic group) or usual care at home by the district nursing service (control group). MAIN OUTCOME MEASURES: Time to complete ulcer healing, patient health status, and recurrence of ulcers. Satisfaction with care, use of services, and personal costs were also monitored. RESULTS: The ulcers of patients in the clinic group tended to heal sooner than those in the control group over the whole 12 month follow up (log rank P=0.03). At 12 weeks, 34% of patients in the clinic group were healed compared with 24% in the control. The crude initial healing rate of ulcers in intervention compared with control patients was 1.45 (95% confidence interval 1.04 to 2. 03). No significant differences were found between the groups in health status. Mean total NHS costs were 878.06 pounds per year for the clinic group and 859.34 pounds for the control (P=0.89). CONCLUSIONS: Community based leg ulcer clinics with trained nurses using four layer bandaging is more effective than traditional home based treatment. This benefit is achieved at a small additional cost and could be delivered at reduced cost if certain service configurations were used.

Aged↗

Quality control in chronic wound management: the role of local povidone-iodine (Betadine) therapy.

BACKGROUND: The treatment of venous leg ulcers is often inadequate, because of incorrect diagnosis, overuse of systemic antibiotics and inadequate use of compression therapy. Stasis dermatitis related to chronic venous insufficiency accompanied by infected superficial ulcers must be differentiated from erysipelas, cellulitis and contact eczema. OBJECTIVES: To assess the effectiveness of (1) topical povidone-iodine with and (2) without compression bandages, (3) to compare the efficacy of systemic antibiotics and topical antimicrobial agents to prevent the progression of superficial skin ulcers. PATIENTS AND METHODS: 63 patients presenting ulcerated stasis dermatitis due to deep venous refluxes were included in the study. The clinical stage of all patients was homogeneous determined by clinical, aetiological, anatomical and pathological classification. They were examined by taking a bacteriological swab from their ulcer area. Compression bandages were used in a total of 42 patients. Twenty-one patients with superficial infected (Staphylococcus aureus) ulcers were treated locally with povidone-iodine (Betadine), and 21 patients were treated with systemic antibiotics (amoxicillin). Twenty-one patients were treated locally with Betadine but did not use compression. The end point was the time of ulcus healing. The healing process of the ulcers was related to the impact of bacterial colonization and clinical signs of infection. RESULTS: Compression increases the ulcer healing rate compared with no compression. Using the same local povidone-iodine (Betadine) treatment with compression bandages is more effective (82%) for ulcus healing than without compression therapy (62%). The healing rate of ulcers treated with systemic antibiotics was not significantly better (85%) than that of the Betadine group. Using systemic antibiotics, the relapse rate of superficial bacterial infections (impetigo, folliculitis) was significantly higher (32%) than in patients with local disinfection (11%). CONCLUSION: Compression is essential in the mobilization of the interstitial lymphatic fluid from the region of stasis dermatitis. Topical disinfection and appropriate wound dressings are important to prevent wound infection. Systemic antibiotics are necessary only in systemic infections (fever, lymphangitis, lymphadenopathy, erysipelas).

Aged↗

Managing and promoting change: implementing the Leg Club model.

Patient knowledge of their disease may increase concordance to compression therapy. The Lindsay Leg Club model (Lindsay, 2004) empowers the community nursing team to truly get to know their communities and deliver local, high-quality, evidence-based care for patients with leg ulcers and leg related problems. The author's experience of opening a Leg Club has lead to changes in clinical practice: re-evaluation of the use of long stretch bandages in favour of short stretch; replacing conventional compression bandage systems with two piece graduated compression hosiery; increased patient concordance post healing with increased use of compression hosiery; the introduction of toe bandaging and appropriate long-term management for those patients with lymphoedema; and developing the role of the nursing auxiliary in leg ulcer care.

Bandages↗

Healing venous ulcers with cycloidal multidirectional vibration therapy.

OBJECTIVE: This preliminary study combined compression bandaging with cycloidal vibration to determine whether this would enhance the rate of healing of venous leg ulceration. METHOD: Twenty-one patients with venous ulceration were enrolled into a 12-week trial. The vibration device was used three times daily for 30 minutes on each occasion, along with compression bandaging. RESULTS: Ulcers of 13 patients (62%) healed within 12 weeks. The remaining eight patients completed the 12-week study with a 31-90% reduction in ulcer size. A reduction in pain was observed in 17 out of 21 patients (81%). Ultrasound measurements showed reduced fluid content in the upper dermis in patients whose ulcers had healed and in others whose ulcers were improving. CONCLUSION: This preliminary study shows that gentle cycloid vibration, combined with standard compression bandaging, enhances the healing rate of venous ulcers and helps to relieve pain.

Aged↗

Evaluation of SurePress Comfort: a new compression system for the management of venous leg ulcers.

OBJECTIVE: The primary aim was to compare the healing of venous leg ulcers after management with either a new compression stocking (SurePress Comfort, ConvaTec) or a standard short-stretch bandage system (Comprilan, BSN Medical GmbH & Co). Secondary parameters included healing rate, ease of application and removal, comfort during wear, local pain levels and concordance. METHOD: This was a prospective multicentre open-label comparative randomised controlled parallel-group pilot trial of 12 weeks' duration. RESULTS: The proportion of ulcers that healed in 12 weeks (44.4% versus 17.2%, p=0.027) and the average time to healing (72 +/- 5 days versus 101 +/- 7 days, p=0.0265) were significantly better with SurePress Comfort than the comparator. All the secondary parameters (except concordance) also showed statistically significant differences for the stocking over the comparator. CONCLUSION: SurePress Comfort stocking system is more effective than a standard short-stretch compression bandage in healing venous leg ulcers and in reducing associated pain. It is well accepted by patients due to its ease of use and comfort, and its safety profile is comparable to that of a standard compression system. It may therefore provide an effective solution for the delivery of graduated compression and has the potential to improve concordance, compared with short- stretch bandages. DECLARATION OF INTEREST: This study was sponsored by ConvaTec.

Adult↗

Optimal management of chronic leg ulcers in the elderly.

Chronic leg ulceration is a very common clinical problem in the elderly. Good management depends entirely on making an accurate diagnosis, and planning treatment after considering all aspects of patient well-being. All elderly patients with leg ulcers benefit from an assessment of their vascular status, since the effects of gravity influence treatment and healing irrespective of the diagnosis. The most common causes of ulceration are venous and arterial disease. Diabetes mellitus, pressure, vasculitis, metabolic abnormalities and skin cancer are all unusual causes of leg ulceration, but must be considered in the differential diagnosis. Almost all patients with ulcerated legs benefit from the use of compression bandaging at a level appropriate to their vascular status. In patients with venous ulcers, this can be achieved with a number of bandaging techniques; however, multilayer bandaging appears to be the most cost-effective means available, particularly when combined with community-based leg ulcer clinics. The effects of oral drug therapy for venous and arterial disease have been disappointing. Local dressings are important in ulcers that are not suitable for compression therapy. The choice of dressing depends on the nature of the ulcer and the tolerability of the dressing for the patient.

Administration, Oral↗

In vitro evaluation of nonrigid support systems for the equine metacarpophalangeal joint.

Metacarpophalangeal (MCP) joint extension is primarily resisted by the digital flexor tendons and suspensory ligament. A variety of external support techniques are used to protect these supporting structures from or after injury by resisting MCP joint extension, although not all are effective and/or practical for use in an exercising horse. In this study, 7 forelimbs were loaded in vitro to determine the effect of a simple gamgee bandage, a 3-layered bandage with and without a contoured palmar splint, a neoprene exercise boot, and an innovative carbon fibre composite exercise boot (Dalmar tendon support boot). There was no significant resistance to MCP joint extension by the gamgee or neoprene exercise boot. The 3-layered bandage had a significant (P<0.01) supporting effect at MCP angles of > or = 245 degrees, and when combined with the contoured splint at angles of > or = 230 degrees. The Dalmar tendon support boot resisted MCP extension at angles of > or = 245 degrees (settings 1 and 2) and > or = 225 degrees (setting 3). These data demonstrate that the contoured splint and the Dalmar tendon support boot (which is also easily fitted for use during exercise) are useful for the management of tendon/ligament injury and during rehabilitation.

Animals↗

New splinting materials.

Plaster of Paris (P.o.P.) bandage has been the pre-eminent external splinting material for over 150 years and from time to time synthetic alternatives have been tried. So far none has seriously challenged the dominance of P.o.P. as a primary or secondary material in the management of fractures. The recent introduction of Polyurethane coated fibreglass bandage appears to offer a more serious challenge than previous contenders. This technical note reviews bandage type splinting materials and explains some of the properties of the PU materials.

Bandages↗

Liquid covering for superficial skin wounds and its effect on wound closure in guinea pigs.

An irrigatable bandage has been developed to hold fluid over a wound. Starting with superficial skin wounds on the back of guinea pigs, the bandage has been used to hold saline or phosphate-buffered saline containing antibiotics over the wound for up to 48 hours. Animals tolerated the bandage well for this period and bacterial contamination and wound maceration were not complications. The extent of reepithelialization with time was measured histologically under three separate conditions: wound exposed to air, wound covered and kept moist, and wound covered with liquid. By 24 hours 2 +/- 1%, 16 +/- 4% and 60 +/- 8% of the wound surface interfollicular areas showed some reepithelialization, respectively. On the average, at the same time these areas showed 15 +/- 2%, 19 +/- 2% and 37 +/- 1% coverage by epithelium. By these measurements, the liquid cover enhanced the rate of wound closure significantly.

Air↗

Post-mastectomy lymphoedema treatment and measurement.

OBJECTIVE: To evaluate multimodal treatment (massage, pneumatic compression, bandaging and education) of post-mastectomy lymphoedema and to review methods of measurement of lymphoedema. DESIGN: Prospective cohort study with 12 months' follow-up. PATIENTS: Twenty-five consecutive women referred for lymphoedema examination after mastectomy to a private day-patient clinic attached to a tertiary referral hospital. INTERVENTION: Patients received multimodal therapy, including education on self-management techniques, for four weeks. MAIN OUTCOME MEASURES: Changes in body weight, limb circumference and volume, and patient reports of self-management (exercise, massage, bandaging and sleeve wearing). RESULTS: Excess limb volume decreased by approximately 40% immediately after treatment and by over 50% at 6 months' follow-up, remaining stable to 12 months' follow-up. Self-management that required assistance (massage and bandage wearing) declined more after treatment than did exercise or compression sleeve wearing. Correlations between body mass and limb volume and self-management and limb volume reduction were non-significant. CONCLUSION: Multimodal therapy reduced lymphoedematous limb volume by at least half in 18 of 25 patients. Patients can maintain these reductions independently through exercise and sleeve wearing and without further treatment. We used a replicable method of measuring lymphoedema, which we recommend for adoption by researchers in this field.

Arm↗

Volume reduction of arm lymphoedema.

Most of the volume reduction in an 11-day course of compression bandaging for severe cancer-related arm lymphoedema appeared to occur in the first few days. This study therefore compared the volume loss during days 1-4 with 5-11. Fifteen consecutive courses of bandaging were studied. Arm volume was estimated on days 1, 5 and 11. The volume reduction during days 1-4 was compared with days 5-11 using the Wilcoxan Ranked Pairs Test. Seventy nine per cent of the total median volume reduction occurred during days 1-4. The difference between the two periods was highly significant (p < 0.001). The duration of compression bandaging has therefore been reduced to 4 days for severe cancer-related arm lymphoedema in this clinic.

Bandages↗

[Compression treatment in venous and lymphatic flow disorders of the leg].

Based on our investigations, the mode of action of compression bandages is discussed ant the physiological and physical principles of this therapy are reviewed. The different basic forms of compression therapy, for example, non-elastic bandages, elastic bandages, use of foam rubber and sponge rubber inserts as well as compression stockings, are mentioned. The side effectes of compression therapy are treated and the indications for compression therapy in superficial and deep thromboses, postthrombotic syndrome and lymphedema are discussed.

Bandages↗