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At least 1,351 records · Page 75Linked to original sources
PubMed1980

Adenoid cystic carcinoma of the salivary glands.

Among 334 malignant tumours of the salivary glands 62 (18.6%) were adenoid cystic carcinomas. Although this tumour grows slowly, local recurrence and metastatic spread, particularly to lung, are common. The recommended treatment is surgical excision followed by radiotherapy. Postoperative irradiation reduces the frequency of local recurrence caused by residual microscopic disease. The 5- to 10-year actuarial survival rates were 77% and 57%, respectively. Local and regional recurrence can be eradicated by aggressive treatment, either by radical operation or a combination of operation and irradiation.

Adult↗
PubMed1981

[The influence of therapy on adenoid cystic carcinomas of the parotid gland (author's transl)].

The occurrence of adenoid cystic carcinomas of the parotid gland is relatively uncommon. From 1964-1974, we performed surgery on 20 patients with such tumors. In these patients, the course of the disease was characterized by local recurrences, the formation of hematogeneous metastases, and long survival times. We have found that patient prognosis is distinctly influenced by the histological type of the neoplasm. Thus, the tubular form has a much better prognosis than the cribriform or the solid types of tumors. On the basis of the "determinate survival rate" of our patients, we were unable to demonstrate a definite positive effect of either radical surgery or radiation therapy on the course of the disease.

Adolescent↗
PubMedDate not supplied

[Carcinoid tumors, adenoid-cystic carcinomas and muco-epidermoid carcinomas of the tracheo-bronchial tree (author's transl)].

A retrospective study of 25 cases with a so-called bronchial adenoma was made. Classification by this old-fashioned nomenclature included 76% carcinoid tumors, 20% adenoid-cystic carcinomas and 4% muco-epidermoid carcinomas of the trachea and bronchial tree. With regard to their malignant potential, the correlation between histological differentiation, invasiveness, metastatic spread and clinical evolution is discussed. An outline of the extent of therapy for each of the 3 types is given.

Adolescent↗
PubMed1981

Primary adenoid cystic carcinoma of the esophagus.

Primary adenoid cystic carcinoma or cylindroma of the esophagus is rare, only 22 cases having been reported previously. The histogenesis of this tumour is disputed, but it is believed to arise from the submucosal glands. A 75-year-old man with a cylindroma of the esophagus underwent radical excision of the tumour and has been clinically disease-free and asymptomatic since his operation in February 1979. Despite the poor results of surgery in the small number of patients reported in the literature, this unusual type of adenocarcinoma of the esophagus should be treated like epidermoid carcinoma--by radical excision.

Aged↗
PubMedDate not supplied

Adenoid cystic carcinoma: a third type of human salivary gland neoplasms characterized cytogenetically by reciprocal translocations.

Using G-banding technique, the chromosomes were studied in four consecutive preparations from cultured material from a human adenoid cystic carcinoma of the submandibular gland. The results indicated that the carcinoma had originated with a normal diploid stemline, and that reciprocal translocations played a predominant role in development of an abnormal stemline. The propensity of developing variant cells, as well as an abnormal stemline, characterized by various types of reciprocal translocations, was found to be a property shared by two other types of salivary gland neoplasms studied by banding techniques, namely the pleomorphic adenoma and the acinic cell tumour. The tissue of origin is suggested to be the crucial determinant responsible for this important cytogenetical similarity between different types of salivary gland tumours.

Adenocarcinoma↗
PubMed1983

[Clinical and histological studies of adenoid cystic carcinoma].

Forty-four salivary gland tumors were seen at The Center for Adult Diseases, Osaka, between 1979 and 1981; 30 were benign and 14 malignant. Of the latter, 7 (50%) were adenoid cystic carcinoma (ACC). Six of 7 ACC were reviewed with special attention to their histologic pattern, atypism, connective tissue around the cell nest, tumor cell nest, tumor cell invasion into lymphatics(ly) and blood vessels(v), and mitosis. ACC was divided into 3 histological groups. Patients with ly and/or v develop cervical and/or distant metastases at the early stage or during the follow-up period. Ly and v were closely correlated with metastasis.

Carcinoma, Adenoid Cystic↗
PubMed1983

[Adenoid cystic carcinoma of the breast--a case report].

We report a rare case of adenoid cystic carcinoma (ACC) of the breast. The patient was a 60-year-old female with a lump of the left breast which had present for 20 years. Macroscopically, the resected left breast tumor was well defined, 7.5 X 7 X 5 cm in size, oval shaped, yellowish gray-white and solid, parts of the tumor showed cystic appearance. Microscopic study revealed a cribriform pattern and alveolar proliferation of uniform, small cells forming cysts, and duct-like spaces which contained mucous content. Each tumor nest was surrounded by hyaline stroma. Alcian blue-PAS staining showed that the cysts were alcian blue-positive; the ducts were PAS-positive. The tumor was diagnosed as ACC of the breast.

Breast Neoplasms↗
PubMed1978

[Cor pulmonale due to upper airway obstruction by hypertrophied tonsils and adenoids (author's transl)].

A case of cor pulmonale is reported, due to chronic nasopharyngeal obstruction by hypertrophied tonsils and adenoids. This syndrome is characterized by stridor, somnolence, arterial hypoxia and hypercarbia, pulmonary and right heart failure. The pathogenesis of this syndrome is due to pulmonary hypoventilation. After tonsillectomy and adenoidectomy the symptoms disappeared.

Adenoids↗
PubMed1994

[Bilateral multiple pulmonary coin lesions--adenoid cystic carcinoma of the lung with 14-year follow-up].

The authors report on an adenoid cystic carcinoma (ACC) of the lung that had been discovered by chance 14 years before the death of the patient and that had at first been interpreted morphologically as a metastatic lung or as a bronchioalveolar carcinoma. The patient remained without any complaints for 13 years. Diagnosis of ACC became possible only by means of a renewed peripheral lung biopsy. An extrapulmonary primary tumour was excluded by postmortem examination. The disease pattern and the special course of the ACC are described.

Adult↗
PubMedDate not supplied

Adenoid cystic carcinoma of the tracheobronchial system: the role of postoperative radiotherapy.

To clarify the role of postoperative radiotherapy for adenoid cystic carcinoma of the tracheobronchial system (ACC), we analyzed patients treated at the National Cancer Center Hospital, Tokyo. Seven patients with ACC were treated with resective surgery and postoperative radiotherapy from 1962-1990. None of the primary lesions was completely surgically resected. Postoperative irradiation was delivered by standard fractionation at a dose range of 49.2-72 Gy. Four of seven patients lived more than 5 years, up to 21 years, without local recurrence. In contrast, three other patients who showed recurrence within 2 years died of disease before 5 years. Three of four patients who received postoperative irradiation of 60 Gy or more attained local control. One of three patients who received less than 60 Gy failed locally. A high dose of postoperative radiotherapy for patients with a positive surgical margin of ACC seems to improve local control and result in long-term survival.

Adult↗
PubMed1995

[Cystic adenoid carcinoma of the esophagus. Description of a case and review of the literature].

The clinical and histopathologic characteristics of a case of adenoid cystic carcinoma of the esophagus are reported. The authors reviewed the literature on the matter and stressed the more aggressive behaviour of the tumor that differs from the same tumor of the salivary glands and other anatomical sites. Surgical resection is the treatment of choice, however the aggressiveness of the tumor requires, also, a chemo and radiotherapeutic approach.

Carcinoma, Adenoid Cystic↗
PubMed1995

Adenoid cystic carcinoma of the head and neck: a clinicopathologic study of 37 cases.

The records of 37 patients with histopathologically confirmed adenoid cystic carcinoma, who presented to McGill University's Department of Otolaryngology between 1956 and 1990, were reviewed to determine factors influencing local failure, distant metastases, and survival. Of the 37 cases, 12 developed local recurrences. Local failure was seen an average of 3.5 years following initial treatment, 62% of which were seen prior to 2 years. No statistically significant advantage was found for the use of postoperative radiotherapy in the prevention of local recurrences. Thirteen cases presented with or subsequently developed distant metastases. The mean interval between initial treatment and the appearance of distant disease was 8.1 years. A comparison of survival in patients with negative versus positive surgical margins was carried out. Survival at 15 years with negative margins remained 100%, while with positive margins, only 35% survived. Disease-free survival with negative and positive margins at 10 years was 80% and 31.1%, respectively. The effect of positive margins on survival was statistically significant with a p values between .01 and .001. The aim of this study was to demonstrate the importance of negative surgical margins with regard to survival. The results suggest that negative margins at initial resection significantly improve long-term disease-free survival.

Actuarial Analysis↗
PubMedDate not supplied

The aryepiglottic fold as a rare location of adenoid cystic carcinoma.

We report one case of a mass in the aryepiglottic fold seen on CT, which proved to be an adenoid cystic carcinoma. There was nothing specific about the imaging characteristics that would allow it to be confidentially differentiated from squamous cell carcinoma.

Carcinoma, Adenoid Cystic↗
PubMed1994

Cephalometric evaluation of pharynx, soft palate, adenoid tissue, tongue, and hyoid bone following the use of a mandibular repositioning appliance in obstructive sleep apnea patients.

The aim of this study was to evaluate the pharynx, soft palate, adenoid tissue, tongue, and hyoid bone when a mandibular repositioning appliance was used for managing patients with obstructive sleep apnea. Lateral cephalograms of 45 adult obstructive sleep apnea patients from the Lancaster Cleft Palate Clinic were taken without the appliance and some days later with the device in the mouth. This device was used during sleep for improving patients' respiration. Twenty-four cephalometric variables were evaluated. When the appliance was in the mouth, significant alterations (P < .001) were observed in the distances: (a) between anterior and posterior pharyngeal walls at the level of the second and third cervical vertebrae, respectively; (b) between the most superior point of the tongue and the maxillary plane; and (c) between the hyoid bone and the mandibular plane, ramus plane, cervical vertebrae tangent, mandibular symphysis, gonion, and third and fourth cervical vertebrae. The results of this study indicate that significant changes in pharyngeal space, hyoid bone, and tongue positions take place in obstructive sleep apnea patients when a mandibular repositioning device is used.

Adenoids↗
PubMed1994

[Adenoid cystic carcinoma. Apropos of a case localized in the lacrimal apparatus].

The authors report one case of adenoid cystic carcinoma of the medical canthus of the orbit. This carcinoma is typified by slow but aggressive growth with multiple local recurrences. Surgery is necessary but radical excision with total exenteration is a difficult decision. Radiotherapy associated to surgery might be usefull.

Aged↗
PubMed1994

[Recurrent secretory otitis media and adenoidism. A retrospective study of the results observed with the medical and surgical therapy of 1250 children].

A retrospective study, between 1982 and 1993, on 1250 children with otitis media with effusion and hypertrophic adenoids was carried out. 1150 children were selected from those who had been administered S-carboxymethylcysteine-lysine for three months period, and antihistaminics, decongestants and anti-inflammatory drugs as concomitant treatment and 100 children from those who had undergone adenoidectomy. ORL-examination, audiometry and tympanometry, before and after the period of the therapy, were performed. No significant differences were found between the two groups with a percentage of successful outcome of 77-79%. On the basis of the data obtained, the tendency of avoiding surgical management by using the appropriate pharmacological therapy is underlined, particularly taking into consideration the safety profile of the medical treatment.

Adenoidectomy↗