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[Effect of thyrocalcitonin on mineral metabolism in experimental osteoporosis].

By the method of radioactive indication of ashed specimens of the femur, tibia, jaw bones and molars on a model of experimental osteoporosis in rats it is shown that the degree of mineralization of calcified tissues increases under the effect of thyrocalcitonin (TCT). The hypermineralization of jaw bones and, especially, of molars was attended by a lower 45Ca inclusion in these tissues. The structure of the adrenal cortex, kidneys, pancreas and thyroid returned back to normal under the effect of TCT and with carbohydrate rich nutrition, this occurring against the background of a high 45Ca concentration in these organs.

Animals↗
PubMed1984

In vivo remineralization of artificial subsurface lesions in human enamel. I.

In this paper in vivo remineralization of artificial subsurface lesions in human enamel, placed in partial prostheses of 30 patients during 3 months is presented. The patients were divided into 3 groups. Group A brushed daily with H2O: group B brushed with H2O and rinsed with a neutral 50 ppm F- solution and group C brushed with a neutral 1500 ppm F- toothpaste. Microhardness indentation measurements were carried out at the start of the experiment and after 2, 4, 16, 20, 44, 58 and 87 days. After 3 months, the indentation length reductions (in %) were for group A, B and C 16, 13 and 20%, respectively. These differences were all statistically significant at least at the p less than 0.05 level. In conclusion, subsurface lesions remineralize very slowly in vivo, much slower than in vitro situations. The remineralization rate is relatively fast in the first 2 weeks; for longer periods the remineralization rate of subsurface enamel lesions is very slow.

Dental Caries↗