Meier-Gorlin (ear-patella-short stature) syndrome: growth hormone deficiency and previously unrecognized findings.
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We measured patellofemoral contact areas and pressures using pressure sensitive film in ten human cadaver knees exhibiting degenerative lesions of patellar cartilage. We studied a flexion range from 20 degrees to 90 degrees and compared contact pressures before and after capsular reconstructive procedures. With an intact, normal capsule, localized lesions of grade I-II exhibited a 50% reduction in pressure (from 3.4 +/- 0.7 MPa to 1.6 +/- 0.9 MPa) directly over the lesion. Grade III-IV lesions exhibited a loss of contact pressure greater than 90%. This reduction in pressure appears to result from a loss of stiffness in the low-grade cartilage lesions and from a loss of cartilage thickness in higher grade lesions. Highly localized peak pressures were also observed on the normal cartilage bordering the lesions. Capsular reconstructive procedures (medial plication, lateral plication, lateral release, and bilateral release) did not result in consistent pressure reductions or in the creation of more uniform pressure distributions. In particular, lateral capsular release, a popular surgical procedure, resulted in no change in three knees and four different pressure patterns in the other seven knees.
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Sixty seven patients with pain in the knee were studied. A compound tomography (CT) score indicating chondromalacia was devised, based on the results of CT after arthrography. This score takes account of the regularity, the congruity, and the imbibition of contrast material. Thus the patients could be divided into four groups: those who definitely have chondromalacia (++), probably (+), probably not (+/-), and definitely not (-). These results were compared with the clinical diagnosis based on clinical signs, arthroscopy, or operation. Eighteen patients had clinically proved chondromalacia, CT scored 14++, 3+ and 1+/-. Twenty nine patients had no chondromalacia, CT scored 19-, 8+/-, and 2+. Twenty patients had an uncertain clinical diagnosis. Arthrography was less accurate in detecting chondromalacia.
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