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PubMedDate not supplied

[Intraneuronal information processing. Delay in the changes in membrane potential after administration of cyclic nucleotides].

Depolarization of the neuron membrane induced by cyclic adenosine monophosphate (cAMP) was shown both by ionophoresis and by injection with pressure. Swelling of the neuron during the injection of various substances with pressure causes membrane depolarization which is similar to that induced by cAMP. When applying pressure the cAMP effect can be distinguished by introducing small volumes of concentrated solutions. Similarity between the effects of cAMP and mechanical stimulation of the neuron suggests that in both cases the effect involves action of the electromechanical system consisting of microskeleton and micromuscles which regulate permeability of molecular channels. The delay of the effect after the moment of cAMP and cGMP introduction is small, which enables a conclusion concerning their direct interaction with the cytoskeleton.

Adenosine Triphosphate↗
PubMed1987

Computer simulations of neural information processing and the schizophrenia-mania dichotomy.

Recent developments in artificial intelligence use computer simulations of complex neural systems to model associative memory and gestalt-seeking during cognition. Perturbations imposed on such computer simulations caused catastrophic breakdowns of neural functioning. The resulting cognitive disturbances assumed two forms, one "schizophreniclike" and the other "maniclike." The former was induced by memory overload and resulted in misperceptions, loose associations, and also parasitic processing states that pathologically controlled the flow of associations. The latter was caused by increased randomness of neural activity, which induced "jumps" from one gestalt to another. The relationship between this differential model of psychotic disturbances and other studies of schizophrenia and mania were explored.

Arousal↗
PubMed1996

The floating population: an informal process of urbanisation in China.

"This paper attempts to employ substantial source materials to shed light on the characteristics of population migration in a centrally planned society that is in the process of transforming to a market economy. In order to compare rural-urban migration in China with that in other developing countries, the data on 1985-1990 interprovincial population migration have been analysed. Some demographic research techniques on population migration, such as the impact on the place of origin and the place of destination, have been employed to assess the influence of rural-urban migration on China's long-term economic development. Economic betterment appears to be the sole motivation of rural population migration in China."

Asia↗
PubMed2000

The human red nucleus and lateral cerebellum in supporting roles for sensory information processing.

A functional MRI study compared activation in the red nucleus to that in the lateral cerebellar dentate nucleus during passive and active tactile discrimination tasks. The study pursued recent neuroimaging results suggesting that the cerebellum may be more associated with sensory processing than with the control of movement for its own sake. Because the red nucleus interacts closely with the cerebellum, the possibility was examined that activity in red nucleus might also be driven by the requirement for tactile sensory processing with the fingers rather than by finger movement alone. The red and dentate nuclei were about 300% more active (a combination of activation areas and intensities) during passive (non-motor) tactile stimulation when discrimination was required than when it was not. Thus, the red nucleus was activated by purely sensory stimuli even in the absence of the opportunity to coordinate finger movements or to use the sensory cues to guide movement. The red and dentate nuclei were about 70% more active during active tactile tasks when discrimination was required than when it was not (i.e., for simple finger movements alone). Thus, the red nucleus was most active when the fingers were being used for tactile sensory discrimination. In both the passive and active tactile tasks, the observed activation had a contralateralized pattern, with stronger activation in the left red nucleus and right dentate nucleus. Significant covariation was observed between activity in the red nucleus and the contralateral dentate during the discrimination tasks and no significant correlation between the red nucleus and the contralateral dentate activity was detected during the two non-discrimination tasks. The observed interregional covariance and contralateralized activation patterns suggest strong functional connectivity during tactile discrimination tasks. Overall, the pattern of findings suggests that the activity in the red nucleus, as in the lateral cerebellum, is more driven by the requirements for sensory processing than by motor coordination per se.

Adult↗
PubMed1978

The nature of deficit among paranoid and nonparanoid schizophrenics in the interpretation of sentences: an information processing approach.

Compared paranoid and nonparanoid schizophrenics to normal controls on a sentence verification task. The task permitted separation of times taken for central scanning and comparison operations and for operations associated with response selection and response execution. Neither group of schizophrenics took more time than normal controls for the latter operations; however, both groups of schizophrenics took longer at central scanning and comparison. Performance on this task was compared to previous results in which schizophrenics were similar to normals on times for central scanning and comparison, but took longer for non-central aspects of processing. It was condluded that the present deficit at the central processing level was attributable to deficient short-term memory of the encoded version of the sentence during the scanning and comparison operations. The absence of differences in the time taken for the non-central operations was ascribed to the exclusion of sentence encoding from the present latency times.

Adult↗
PubMed2000

Initial development of the expectations test for children: a tool to investigate social information processing.

This research describes the initial development of a new measure to assess the expectations of children for social situations. Responses are provided to 16 ambiguous photographs of children. Answers identify expectations for how the child will feel and what will happen to the child in each picture. The value of expectations in identifying and understanding psychopathology was investigated. The effects of child abuse and the parent-child relationship on expectations were studied. Results begin to demonstrate the potential for clinical use, interrater reliability, internal consistency, and validity. Future development is discussed with the caution that limited variance is explained by the Expectations Test at this point.

Adolescent↗
PubMed1993

Demographic and clinical correlates of selective information processing in patients with bulimia nervosa.

Demographic and clinical correlates of interference with color-naming words related to eating, weight, and shape were investigated in 75 patients with bulimia nervosa. Interference with color-naming was related to two measures, overall level of psychiatric symptoms and frequency of purging. Multiple regression analysis showed that frequency of purging, and not level of general psychiatric symptoms, was the best predictor of interference. Thus, as would be predicted by cognitive theories, interference appears to be most closely related to features specific to bulimia nervosa rather than to measures of general psychopathology.

Adolescent↗
PubMed2004

The effects of rational and experiential information processing of expert testimony in death penalty cases.

Past research examining the effects of actuarial and clinical expert testimony on defendants' dangerousness in Texas death penalty sentencing has found that jurors are more influenced by less scientific pure clinical expert testimony and less influenced by more scientific actuarial expert testimony (Krauss & Lee, 2003; Krauss & Sales, 2001). By applying cognitive-experiential self-theory (CEST) to juror decision-making, the present study was undertaken in an attempt to offer a theoretical rationale for these findings. Based on past CEST research, 163 mock jurors were either directed into a rational mode or experiential mode of processing. Consistent with CEST and inconsistent with previous research using the same stimulus materials, results demonstrate that jurors in a rational mode of processing more heavily weighted actuarial expert testimony in their dangerousness assessments, while those jurors in the experiential condition were more influenced by clinical expert testimony. The policy implications of these findings are discussed.

Adolescent↗
PubMed2003

Three streams of visual information processing in V2 of Cebus monkey.

Gattass and collaborators (Gattass R, Rosa MGP, Souza APB, Piñon MCG, Neuenschwander S [1990a] Braz J Med Biol Res 23:375-393) proposed that the dorsal stream of visual processing, as defined by Ungerleider and Mishkin (Ungerleider LG, Mishkin M [1982] In: Ingle DJ, Goodale MA, Mansfield RJW, editors. Analysis of visual behavior. Cambridge: Massachusetts Institute of Technology. p 549-586), can be subdivided into dorsolateral and dorsomedial streams, and suggested that they may be involved in different aspects of the processing of motion and spatial perception, respectively. The goal of the present study was to provide additional evidence for this hypothesis by using cytochrome oxidase immunohistochemistry combined with retrograde tracing techniques. In Old World monkeys, the locations of visual area 4 (V4; ventral stream) and middle temporal area (MT; dorsal stream) projecting neurons in V2 supports the hypothesis that the cytochrome oxidase (CytOx)-rich thin stripes and the CytOx-poor interstripes are associated with the ventral stream, and that the CytOx-rich thick stripes belong to the dorsal stream. In this study we describe, in the New World monkey Cebus, the distribution of retrogradely labeled cells in V2 relative to the CytOx compartments after fluorescent tracers were placed in areas V4, MT, and the parietooccipital area (PO). We found PO-projecting neurons in CytOx-rich thick stripes and CytOx-poor interstripes in V2, whereas MT-projecting neurons appeared almost exclusively in thick stripes. In contrast, V4-projecting neurons were located mostly in CytOx-poor interstripes and CytOx-rich thin stripes. In addition, V4- and MT-projecting neurons were located mainly in supragranular layers, whereas PO-projecting neurons were located in supragranular and infragranular layers. These results support the hypothesis for the existence of three distinct streams of visual processing: ventral (including V4), dorsolateral (including MT), and dorsomedial (including PO).

Animals↗
PubMed1994

Information processing within the motor cortex. II. Intracortical connections between neurons receiving somatosensory cortical input and motor output neurons of the cortex.

Connections between motor cortical neurons receiving somatosensory inputs from area 2 and large pyramidal cells in layer V were examined in the cat via intracellular injection of biocytin and immunohistochemistry of nonphosphorylated neurofilament proteins (npNFP). Biocytin was injected into pyramidal cells in layers II/III of the motor cortex that responded monosynaptically and polysynaptically to microstimulation of the somatosensory cortex and subsequently stained black by the avidin-biotinylated peroxidase complex method with diaminobenzidine (DAB) and nickel. By using a monoclonal antibody SMI-32 and a modified peroxidase-antiperoxidase method with Tris-aminophenyl-methane (TAPM) and p-cresol as a chromogen, pyramidal cells in layers III and V of the motor cortex were stained red for npNFP. In particular, all the large pyramidal cells in layer V, Betz cells, displayed intense npNFP immunoreactivity not only in the perikarya but also in the dendrites. Double staining with DAB/nickel and TAPM/p-cresol showed that biocytin-filled axon varicosities of the pyramidal cells, which were thought to receive monosynaptic inputs from area 2, made contacts with npNFP-positive dendrites in layers I-III around the biocytin-injected cell and in layers V-VI beneath the cell. The present results suggest that the corticocortical input from area 2 to pyramidal cells in layers II/III of the motor cortex is transferred to layer V pyramidal cells, including Betz cells, as well as to neighboring layer II/III pyramidal cells. Since tetanic stimulation of the somatosensory cortex reportedly produces long-term potentiation in layer II/III cells of the motor cortex, it seems reasonable to assume that a given area of the somatosensory cortex can produce a long-lasting change in the activity of a given group of output cells in the motor cortex.

Animals↗
PubMed1995

Using reflexive behaviors of the medicinal leech to study information processing.

The interneuronal network that produces local bending in the leech is distributed, in the sense that most of the interneurons involved are activated in all forms of local bending, even those in which their outputs would produce inappropriate movements. Such networks have been found to control a number of different behaviors in a variety of animals. This article reviews three issues: the physiological and modeling observations that led to the conclusion that local bending in leeches is controlled by a distributed system; what distributed processing means for this and other behaviors; and why the leech interneuronal network may have evolved to be distributed in the first place.

Animals↗