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Costs and methods of preventive visual screening and the relation between esotropia and increasing hypermetropia.

Atkinson has shown that early correction of hypermetropia reduces the incidence of esotropia. If esotropia is reduced by prescribing glasses early, the rate of esotropia-induced amblyopia can be similarly reduced; this would have important economic consequences. We have studied (1) how costs compare to benefits in early visual screening, (2) how videorefraction as used by Atkinson compares to retinoscopy, and (3) whether esotropia is more likely to occur in children who have increasing as opposed to decreasing hypermetropia. The costs of the study so far have been high. It was exceedingly difficult to get all infants invited, come to the clinic and examined. Videorefraction did not compare favourably with retinoscopy in terms of costs and precision, whereas the amount of skill and time needed was approximately equal. The third question, whether esotropia is more likely to occur in children who have increasing as opposed to decreasing hypermetropia, arose from the controversy whether, in the general population, refraction increases or decreases during the first years of life. We found that papers reporting a decrease of hypermetropia in early childhood were studies of large cross-sections of the general population, whereas papers that reported an initial increase originated from ophthalmological practices or strabismus departments. These conflicting results could be reconciled by assuming a population bias: if esotropia is more likely to occur in children with increasing hypermetropia, children with increasing hypermetropia will preferentially be seen by ophthalmologists. It seems natural that children with increasing hypermetropia are more likely to squint, because additional accommodation, needed to overcome increasing hypermetropia, will inevitably confer additional convergence. This relationship has meanwhile been confirmed by others.

Amblyopia↗

Ocular anatomy and refraction.

An examination is made of possible relations between ocular morphology and refraction in man. Special attention is paid to astigmatism, prematurity, the eye at birth, and differences as between the eyes of men and women respectively. Some functional correlates are also pointed out.

Adolescent↗

Pressure lowering effect of timolol with reference to its topical vascular action.

The hemodynamic effect of timolol maleate in open angle glaucoma was studied rheo-oculographically. Increase in the ocular pulse which reaches maximal amplification 2 h after the instillation of the drug was observed. The maximal pressure lowering effect appeared 3 h after instillation, as if the hemodynamic effect were the trigger for the pressure lowering effect.

Administration, Topical↗

[Retinoscopy under cycloplegic and non-cycloplegic conditions in children comparison of measurements of three examiners (author's transl)].

The refractive status of 100 eyes were measured by three ophthalmologists utilizing retinoscopy under non-cycloplegic and cycloplegic conditions. The statistical analysis of the results was done by multiple regression. The retinoscopic measurements of sphere and cylinder of the three examiners show smaller differences under cycloplegic than under non-cycloplegic conditions. The largest differences in the measurements of axis were found in cases of small cylinder power. Especially in children and in patients with strabismus, the authors feel that measurements of the refractive state have to be carried out under cycloplegia.

Accommodation, Ocular↗

Visual function in hypermetropia. An electroretinographic and psychophysical study.

Dark-adapted retinal function was tested electroretinographically and psychophsysically in patients with severe hypermetropia. These patients were first tested in 1982 and were classified into three electroretinographic categories subnormal, normal and supernormal, according to the amplitudes and the b-wave to a-wave relationships of their dark-adapted electroretinographic responses. These patients were invited for a follow-up examination to examine whether the subnormal electroretinogram represented a stationary or a progressive syndrome, to correlate functional vision to the electroretinographic findings and to determine the changes in refraction and electroretinographic responses that might have occurred during an 8-year period. No significant changes were seen in the amplitudes and b-wave to a-wave relationships of the electroretinographic responses. These observations supported the initial electroretinographic classification of the hypermetropic patients and indicated that the patients belonging to the subnormal group were probably characterized by a stationary defect. The psychophysically determined thresholds at different retinal loci (from 30 degrees nasal to 40 degrees temporal) were within the normal range for all the patients regardless of their electroretinographic characteristics. Thus, the abnormal electroretinographic responses of hypermetropic patients probably did not reflect abnormal retinal function but may be accounted for by changes in the electrical resistances of extraretinal tissues relative to that of the retina itself.

Adolescent↗

Form vision deprivation amblyopia: further observations.

Nine cases of esotropia occurring in deprivation amblyopia, where exotropia rather than esotropia is usually found, showed a refractive error of hypermetropia. This fact suggested that an accommodative factor is largely responsible for the development of esotropia. A- or V-pattern strabismus was encountered in a higher incidence in deprivation amblyopia than in ordinary strabismus. Pattern-reversal VEP showed more prominent abnormality than flash VEP did. Studies of the sensitive period of the visual system revealed that the sensitivity is likely to be low for a month or two after birth and increases with a peak around the 18th month of age, decreasing thereafter with a waning slope to the end of the 8th year of life.

Adolescent↗

Retinal correspondence in typical accommodative esotropia.

Typical (refractive) accommodative esotropia is a form of acquired esotropia caused primarily by hypermetropia; correction of the hypermetropic refractive error with convex lenses generally leads to rehabilitation. A significant number of cases clinically diagnosed as typical accommodative esotropia do not, however, respond satisfactorily to this form of treatment, suggesting the presence of nonrefractive etiological factors. Fifty cases diagnosed by conventional methods as typical accommodative esotropia were examined with the fundus haploscope; abnormal or subnormal retinal correspondence was discovered in nearly 50% of the total. Congenital elements are thought to play a contributory role in these cases.

Child↗

Effect of visual environment on refractive error of cats.

33 eyes of 18 cats raised in cages or in small rooms under conditions of near vision were compared with 22 eyes of 11 street cats. Refraction of the caged cats showed that three quarters of them were myopic (average:-0.8 D) while 87.5 percent of the street cats were hypermetropic (average: +1.4 D). The antero-posterior diameter was practically equal in both groups (20.4 mm) and in both myopic and hypermetropic eyes. The site of the permanent refractive changes is suggested to be the lens.

Animals↗