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1,327 records · Page 74Linked to original sources
PubMed2006

A comparison of selected media and incubation temperatures for isolation of microscopic fungi from dried medicinal plants.

The study compared selected media and incubation temperatures for isolation of fungi from dried medicinal plants (chamomile, peppermint, lemon balm, St. John's wort and two herbal mixtures). The DG18 medium was found to be the most suitable for characterization of the mycoflora at 25 degrees C. The medium selection for 37 degrees C was dependent on the species to be isolated. MEA + 40% sacharose and YpSs were found to be the best media for isolation of thermophilic and thermotolerant fungi from dried medicinal plants.

Chamomile↗
PubMed1997

Central action of hyperici herba cum flore extractum siccum in freely moving rats.

The central action of a plant extract containing hyperici herba flore extractum siccum has been investigated in freely moving rats during a 6 h exposure with two dosages. After frequency analysis of local field potentials electrical power changes of delta waves and alpha2 waves (less pronounced) could be observed within the frontal cortex and hippocampus. As these frequencies are changed predominantly in the presence of drugs acting at the cholinergic or dopaminergic transmitter system, a similar mode of action can be suspected for this plant extract. Despite the fact that statistical significance could only be observed during the fourth hour (p <0.1), the changes induced by the higher dose of the extract containing 1 mg of hypericine were very stable from the 2. to 4. hour after oral application. Classification of the parameters obtained by means of discriminant analysis revealed a trend into the direction of antidepressive EEG drug profiles. Results suggest that quantitative EEG analysis is a very sensitive methodology for the description of pharmacodynamic actions of plant extracts and data can be compared to the action of pure chemical entities.

Animals↗
PubMed1995

Pharmacodynamic effects of St. John's Wort on rat intracerebral field potentials.

Two extracts of St. John s Wort were compared with respect to their action on in vivo monitored field potentials from four brain areas of the freely moving rat. Quantitative assessment of the drug action revealed a late onset (3 to 4 hours after oral application) and main effects on the frontal cortex. Changes consisted in electrical power alterations reminiscent of the action of antidepressive and/or analgesic drugs. Particular frequency bands affected first line were alpha1 and alpha2, which in some way are related to serotonergic and dopaminergic transmission. From this it is concluded that St. Johns Wort could be used for the indication of depression with predictable success. The extract labeled "K" turned out to be superior especially after repetitive application and could thus far be used for further studies.

Action Potentials↗
PubMed1997

St. John's wort.

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Antidepressive Agents↗
PubMed1998

St. John's wort.

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Antidepressive Agents↗
PubMed1998

Herbal healers.

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Animals↗