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Consensus recommendations on the use of botulinum toxin type a in facial aesthetics.

The use of botulinum toxin type A for facial enhancement is the most common cosmetic procedure currently undertaken in the United States. Overall clinical and study experience with botulinum toxin type A treatment for facial enhancement has confirmed that it is effective and safe in both the short and long term. Nevertheless, consistent guidelines representing the consensus of experts for aesthetic treatments of areas other than glabellar lines have not been published. Therefore, a panel of experts on the aesthetic uses of Botox Cosmetic (botulinum toxin type A; Allergan, Inc., Irvine, Calif.) was convened to develop consensus guidelines. This publication comprises the recommendations of this panel and provides guidelines on general issues, such as the importance of the aesthetic evaluation and individualization of treatment, reconstitution and handling of the botulinum toxin type A, procedural considerations, dosing and injection-site variables, and patient selection and counseling. In addition, specific considerations and recommendations are provided by treatment area, including glabellar lines, horizontal forehead lines, "crow's feet," "bunny lines" (downward radiating lines on the sides of nose), the perioral area, the dimpled chin, and platysmal bands. The review of each area encompasses the relevant anatomy, specifics on injection locations and techniques, starting doses (total and per injection point), the influence of other variables, such as gender, and assessment and retreatment issues. Factors unique to each area are presented, and the discussion of each treatment area concludes with a review of key elements that can increase the likelihood of a successful outcome. Summary tables are provided throughout.

Botulinum Toxins, Type A↗

'These sorts of people don't do very well': race and allocation of health care resources.

Recent literature has highlighted issues of racial discrimination in medicine. In order to explore the sometimes subtle influence of racial determinants in decisions about resource allocation, we present the case of a 53-year-old Australian Aboriginal woman with end-stage renal failure. The epidemiology of renal failure in the Australian Aboriginal population and amongst other indigenous peoples is discussed. We show that the use of utilitarian outcome criteria for resource allocation may embody subtle racial discrimination where consideration is not given to issues of justice, race, culture and gender. It is only where the processes by which resources are allocated are transparent, clearly defined and based upon consultation with individual patients that issues and justice are likely to be adequately addressed.

Americas↗

Gender differences in anaerobic power of the arms and legs--a scaling issue.

PURPOSE: Physiological variables must be scaled for body size differences to permit meaningful comparisons between groups. Using allometric scaling, this study compared the anaerobic performance, using both arms and legs, of men and women. Ten active male and 10 active female subjects performed the leg cycling and arm cranking in a 30-s all-out Wingate test (WAnT). Regional measurements of the legs, gluteal area, arms, and torso taken using dual-energy x-ray absorptiometry (DXA) served as indicators of lower body active musculature (LBAMM) and upper body (UBAMM) active musculature. RESULTS: Body mass (BM) was the best predictor (i.e., r = 0.93-0.96) for peak power (PP) and mean power (MP) generated from sprint cycling and arm cranking. Sex differences for leg and arm power (i.e., PP and MP) were identified in absolute terms and then expressed in ratio to BM(1.0). When the same data were allometrically scaled to BM and expressed as power function ratios (Power;BM(b)), the sex differences in PP and MP for sprint cycling were nullified (female:male ratio x 100: 100-103%), but remained for arm cranking (female:male power ratio x 100: 69-84%). CONCLUSIONS: These results confirmed that anaerobic power of the upper body and lower body were best normalized to BM and, when statistically appropriate methods were used to take into account differences in BM, PP, and MP generated from sprint cycling were similar for both men and women. In contrast, after allometric scaling for BM, men remained more powerful than women for the supramaximal arm cranking task. Qualitative differences in the upper body musculature between men and women are speculated to account for the more powerful performance of men, but confirmatory evidence using noninvasive techniques is warranted.

Adult↗

The influence of age and gender on the driving patterns of older adults.

The purpose of this study was to investigate the influences of age and gender on the driving patterns of 300 older adults. Odds of driving less than every day increased significantly with age and female gender. However, no differences were found in the reduction of overall driving. Females were more likely than men to have stopped or reduced driving under certain adverse conditions and for elective purposes. The driving patterns of today's cohort of older females suggest that the gender gap may be narrowing. Social and cultural issues such as security, safety, and identity with driving may explain existing gender differences.

Age Factors↗

Work-family issues and perceptions of stress among pediatric faculty and house staff.

OBJECTIVES: To examine work-family balance issues and predictors of stress related to work-family balance among pediatric house staff and faculty. METHODS: Data were obtained through an anonymous mail survey. Univariate analyses assessed associations between work-family issues (work-related factors that affect work-family balance, perceived support, work-family--related stress, and proposed solutions) and the following variables: gender, parental status, working status of spouse, and academic rank. Multiple linear regression examined independent predictors of perceived stress. RESULTS: Fifty percent of the 327 respondents cared for dependent children, and 20% expected to care for an elderly person in the next 5 years. Only 5% strongly agreed that their division or department was concerned about supporting members' work-family balance, and 4% strongly agreed that existing programs supported their needs. Eighty-three percent reported feeling stressed as a result of efforts to balance work and family. Independent predictors of stress included perceived need to choose between career and family, increasing age, dependent children, less support from colleagues and supervisors, and female gender. CONCLUSIONS: Work-family balance issues are responsible for substantial perceived stress. Academic departments should consider a commitment to supporting faculty who are struggling with these issues, including creation of work-family policies and programs, development of mentoring systems, and reexamination of existing expectations for work practices.

Adult↗

Type 2 diabetes mellitus and cognition: an understudied issue in women's health.

INTRODUCTION: Diabetes is a common chronic illness, affecting approximately 16 million Americans, and is slightly more common in women than men. Data from population studies demonstrate that women with diabetes are at greater risk for cardiovascular disease, the leading cause of death among women and an independent risk factor for cognitive decline. Longitudinal epidemiologic studies report an association between diabetes mellitus and vascular dementia, but conflicting data on the association between diabetes and Alzheimer's dementia. Whether type 2 diabetes has an effect on cognitive function, independent of dementia, has received much attention since the 1980s, but the question remains unresolved. METHOD: The literature was rigorously reviewed for studies in which cognitive functioning was measured with neuropsychological (NP) tests in participants with type 2 diabetes and a control/comparison group without diabetes. RESULTS: Of 32 studies that reported the effects of type 2 diabetes on cognition in nondemented middle-aged and older adults, 30 included women in their samples, and two focused exclusively on women. Of studies that included women, 20 (67%) reported that participants with type 2 diabetes performed more poorly than those without diabetics on one or more NP tests, leading the authors to conclude that diabetes is positively associated with cognitive dysfunction. CONCLUSIONS: Owing to the small number of studies with adequate numbers of women to report findings by gender, little is known about the effect of type 2 diabetes on cognition in women. It is critical that studies on type 2 diabetes and cognitive functioning be designed to include women in numbers adequate for examination of gender effects. The discussion addresses issues specific to women that warrant further research.

Cognition↗

Legal implications surrounding adolescent health care decision-making in matters of sex, reproduction, and gender.

This article focuses on the thorny and evolving legal issues and implications of health care decision-making for children and adolescents in matters of gender, sexual identity, sexual conduct, and reproduction. In treating minors, health care professionals increasingly experience competing duties and responsibilities to their patient, the parents or guardians, and to the state. This article gives health care professionals a foundation for understanding the legal concepts of adolescent health care decision-making and provides an approach for balancing the potential competing interests of these stakeholders while complying with professional standards,the law, and their own ethical and moral convictions.

Adolescent↗

Living conditions of adults with intellectual disabilities from a gender perspective.

BACKGROUND: The role of gender has been a neglected issue in research on intellectual disability (ID). People with ID are generally treated as a homogenous group that are largely categorized by their level of ID. This study compared living conditions of women and men with ID and related the results to similarities and differences among the general population in corresponding age groups. METHODS: Persons with ID born in Uppsala County between 1959 and 1974 constituted the study sample. Information on the living conditions of 110 persons with ID was collected using questionnaires completed by relatives and staff. Information on living conditions of the general population was obtained through national welfare statistics conducted by Statistics Sweden (SCB). RESULTS: In both samples corresponding diversities were revealed for type of employment/daily activities, where women worked in traditional female job sectors and men were occupied with traditional male jobs. Women and men with ID participated to about the same extent in recreational and cultural activities and on only four of the 19 activities listed in the questionnaire (visits to the cinema and library, reading books and practising hobbies alone) significant differences were observed. Among women and men in the general population, we found gender-related differences in 13 of the activities listed. However, with the exception of women more frequently visiting the library and reading books, the two samples demonstrated no corresponding gender-related differences. For the remaining six domains (finances, family and social relations, housing, transport, community participation and personal safety), no differences were noted between women and men with ID. This finding contrasted sharply with the differences found between women and men in the general population. CONCLUSIONS: Surprisingly, the comparison yielded few differences in living conditions between women and men with ID compared with those found in women and men of the general population. This finding suggests that people with ID were treated as gender-neutral persons rather than as women and men with individual preferences and needs. Thus, it appears that having ID is a more important determinant than gender regarding living conditions for women and men with ID.

Activities of Daily Living↗

Treatment of alcohol use disorders in adolescents.

The treatment of alcohol use disorders (AUDs) in adolescents is a very important issue in the field of substance use disorders; however, it is a complex and understudied area in which there are limited data concerning evidence-based treatment. The authors first briefly review the epidemiology of AUDs in adolescents, describe existing guidelines for the treatment of such disorders in adolescent patients, and consider differences between AUDs as they present in adolescents and adults. In the next section of the paper, the authors review the assessment and diagnosis of AUDs in adolescents and consider how findings from such assessments will influence subsequent treatment planning. They also describe prognostic factors (e.g., family issues, socioeconomic factors, psychiatric comorbidity, gender, ability to form a therapeutic alliance) that may affect treatment outcome and need to be considered in treatment selection. The various settings in which adolescent AUDs may be treated and the types of patients and situations for which each is most appropriate are described. The second half of the article focuses on the treatment of adolescents with AUDs. The authors describe techniques for establishing abstinence and then preventing subsequent relapse. Although there is an interest in the use of medications (e.g., naltrexone) to treat AUDs in this population, there are unfortunately few if any data concerning the use of these agents in adolescent patients. More data are available concerning psychosocial treatments. The authors describe a variety of psychosocial modalities that have been tested in adolescents, including individual psychotherapy (e.g., interpersonal therapy, cognitive-behavioral therapy, motivational enhancement therapy), group therapies, 12 step/self-help programs, family therapy, skills training for parents, and psychoeducation. The authors then consider the importance of targeting comorbid psychiatric conditions, especially anxiety and depression, in the treatment of AUDs in adolescents. The authors stress the importance of being aware that adolescents with AUDs are at increased risk for violence against self or others and suicide. They also note that practitioners who work with adolescents with AUDs often need to deal with forensic issues (e.g., DUI charges).

Journal Article↗

A social essay on special issues facing poor women of color.

Race, gender, and socioeconomic status place poor women of color in triple jeopardy for subservience. Racism, sexism, impoverishment, and discrimination in a variety of services serve to deny poor women of color the opportunities in education, occupations, income, and health services that are afforded other groups in this country. This paper shows that the fight for civil rights is also one for preventive and quality, accessible and comprehensive care for those who suffer most: poor women of color, and that until this nation is purged of these egregious and reprehensible forces, the goal of a true democracy will continue to elude us.

Achievement↗

Knowledge of contraceptives and sexually transmitted diseases and contraceptive practices amongst young people in Ho Chi Minh City, Vietnam.

In this article, we examine knowledge of contraceptives and sexually transmitted diseases (STDs) and contraceptive practices amongst young Vietnamese people. We conducted a qualitative study on sexuality and abortion with young people in Ho Chi Minh City, Vietnam. Twelve female and 4 male young people were individually interviewed using an in-depth interview technique. We found that condoms and pills were contraceptives known by almost all young people, but their knowledge of condoms and pills was still inadequate. Fears of side effects of taking pills and rumors and beliefs regarding condoms were quite common among young people. The limitations in young people's knowledge of contraceptives and STDs were a reflection of limited sources of their knowledge. Sexual education provided by educational institutions and within families was very basic. It did not provide clear knowledge on the sensitive topics such as contraceptive methods, and other issues related to sexuality for unmarried people. From a gender perspective, there are two points to note here: While sex issues were discussed openly among unmarried men, most unmarried women felt uncomfortable or expressed difficulty when talking about these issues; and the passiveness of unmarried women in making the decision of using condoms as well as contraceptives was marked. Amongst young people, the use of contraceptives was based mainly on ineffective methods including withdrawal and periodic abstinence. Further, young people's understanding of these methods was neither clear nor adequate. For the young people who did not use any contraceptives, sexual relations occurred unexpectedly. We conclude that creating a climate in which sexual issues can be discussed openly is an important step for the improvement of sexual health for young people. This will inevitably improve knowledge and understanding of contraceptives and STDs and may lead to a safer sexual life among this group of young people.

Adult↗

[Gender based psychopharmacology: gender influence in the pharmacological treatment of mental disorders].

Gender-based pharmacology is a new research and clinical area which could be defined by the inclusion of gender-related variables in clinical, research and educational issues with respect to pharmacotherapy. Most of the studies which have studied pharmacokinetic gender differences in psychotropic drugs have found that women tend to have higher plasma concentrations. As regards differences in treatment response, most evidence points to a more rapid response to neuroleptics and lower therapeutic doses in women, and, on the other hand, a possible better response to selective serotonin reuptake inhibitors (SSRI) in premenopausal women. In addition, women appear to have a higher incidence of adverse effects to different psychotropic drugs.

Female↗

Qualitative needs assessment of HIV services among Dominican, Mexican and Central American immigrant populations living in the New York City area.

This paper reports on research designed to assess access to care by Latino immigrant populations in the New York area. A qualitative approach and methods were employed, involving focus groups with PLWAs (persons living with AIDS) and affected men and women from Mexico, the Dominican Republic and Central America to explore the perceptions, beliefs, experiences and knowledge of HIV care issues. A total of 57 men and women participated, ranging in age from 19-61. Results included detailed information on cultural meanings of HIV/AIDS; experience of stigma and rejection; gendered health-seeking behaviour; testing issues; and satisfaction with services. Data support the conclusion that to be effective in reaching and providing services to these immigrant groups, it is crucial to understand the environment from which they come and the impact of immigration. Poverty, repressive governments, lack of education/literacy, ethnicity, class, colour-based stigma and cultural norms are crucial factors in determining their attitudes, motivations, decisions and behaviour. AIDS agencies were seen to play a crucial role in connecting PLWAs to services and resources. The key elements for the provision of services to this population appear to be those that build on cultural norms and network human and institutional resources.

Adult↗

Child growth and nutritional status in a high-poverty community in eastern Kentucky.

The research reported in this paper examines the relationship between household socioeconomic measures, child growth, and nutritional status in a community in eastern Kentucky with a high rate of poverty. It is based on the premise that child growth and nutritional status reflect the social circumstances in which they occur. 21.6% of the children exhibited low height (<15th percentile of National Center for Health Statistics [NCHS] reference values), with 13% of the girls exhibiting stunting (<5th percentile). Thirty-three percent of the children exhibited overweight, and 13% exhibited obesity (>85th percentile and >95th percentile of National Health and Nutrition Examination Survey [NHANES] reference values, respectively); 21.4% of boys were obese, compared to 8.7% of girls. Analysis of variance indicated that child stature is best explained by the father's education level interacting with employment status, and by the mother's employment status interacting with household poverty level. Weight is best explained by the mother's employment status. However, the relationships among socioeconomic measures and growth outcomes differed by gender of the child. These issues are discussed in light of the anthropology literature and the situation in Bridges County, Kentucky where the research took place.

Child↗

Communication analysis of BRCA1 genetic counseling.

In this study, we apply an existing medical communication coding system to BRCA1 genetic counseling sessions, describe the session dynamics, and explore variation in session communication. The sample was comprised of 167 members of an identified BRCA1 kindred whose pretest counseling session was audiotaped and coded using Roter's Interaction Analysis System (RIAS). Three certified genetic counselors followed a research protocol that dictated areas to be covered in the counseling session. We found that it was feasible to code long, protocol driven BRCA1 sessions in a quantitative manner without the use of transcripts and capture the dialogue of all session participants. These findings support the use of RIAS in genetic counseling research. Our results indicate that these BRCA1 sessions were predominantly educational in nature with minimal dialogue devoted to psychosocial issues. We found that participant gender, presence of a client companion, and counselor identity influence session communication.

Communication↗

The burden of hydrocele on men in Northern Ghana.

The social and economic impact of lymphatic filariasis was studied in Northern Ghana. Qualitative methods of gathering information revealed that even though the disease was a problem to both men and women, men with hydrocele suffered a greater psychosocial burden. Particular attention was paid to them, distinguishing men with small hydroceles and men with large ones. Out of frustration men with small hydroceles sought health care from a wider range of places than men with larger ones. The pain associated with adenolymphangitis (ADL) renders them inactive for up to 5 days. Complications of lymph scrotum and ridicule from community members were a problem. Unmarried men in particular found it difficult to find a spouse with their condition, and various degrees of sexual dysfunction were reported amongst married men. The clinical significance and the value of time and attention for counseling to mitigate the effects of the disease on damaged male identity and the need for gender studies to address male issues and the need for including psychosocial issues in the calculating of disability adjusted life years (DALY's) is also discussed.

Adolescent↗

Photoglottographic measures in Parkinson's disease.

This study examines the usefulness of photoglottographic measures in reflecting the phonatory effect of Parkinson's disease. In the first experiment, data obtained by photoglottography were compared between 15 male patients with Parkinson's disease and 15 normal male speakers of similar age. Six photoglottographic parameters, mean open quotient (OQ), mean speed quotient (SQ), perturbation of open quotient (POQ), perturbation of speed quotient (PSQ), frequency perturbation ratio (FPR), and amplitude perturbation ratio (APR), in sustained vowel phonation were investigated. Increased SQ (t = -2.731, df = 28, P = 0.011) and POQ (t = -2.584, df = 28, P = 0.015) were significantly associated with data from patients in comparison to normal speakers. The FPR, APR, and OQ were not significantly different between normal subjects and patients. A follow-up experiment, including 12 female and 19 male patients with Parkinson's disease, was designed to evaluate the sensitivity of SQ and POQ in detecting vocal dysfunction. The sensitivity of SQ was found to be relatively high (93.5%), while that of POQ was low (45.2%). Methodological issues regarding the effects of gender, age, stage of the disease, and treatment on photoglottographic measures in Parkinson's disease were discussed.

Adult↗