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[Capsule endoscopy is better than other methods. 66 examinations performed at Sodersjukhuset prove a high diagnostic yield].

Capsule endoscopy is a non-invasive method to investigate the small intestine by means of a swallowable videocapsule that takes pictures during its passage throughout the gut. The method has been proven to have a high diagnostic yield in obscure GI bleeding and suspected small bowel Crohn's disease in cases where traditional methods have failed. In 63 patients consecutively evaluated by capsule endoscopy pathological lesions were found in 39 (62%), of which angiodysplasias were the most common (33%). Inflammatory changes including Crohn's disease constituted 40% of the findings. Malignant tumors were found in two patients (5%). Half of the patients with patological findings were either medically treated or referred to surgery. Capsule endoscopy is a new method for small bowel examination that has a great potential to replace some older methods with lower diagnostic yield.

Adolescent↗

[Thoracoscopy and intraoperative upper gastrointestinal endoscopy was effective for Boerhaave syndrome; report of a case].

Boerhaave syndrome is a rare disease and needs an exact diagnosis and a proper treatment plan because of its terrible clinical course. We experienced a case of Boerhaave syndrome that thoracoscopy and intraoperative upper gastrointestinal (GI) endoscopy was very effective. Sixty-four-year-old man realized chest and back pain after vomitting. Esophageal perforation was suspected, but 64 hours had passed already when we started a surgical treatment. By the thoracoscopy and intraoperative endoscopy, lower esophageal perforation and infectious pleural effusion were found. Therefore, we selected a surgical treatment under the assistance of thoracoscopy. Secondly, a simple closure and intracostal muscle overlapping was performed with small incisional thoracotomy. Postoperative complication, such as mediastinal abscess, has not occurred. Thoracoscopy and intraoperative upper GI endoscopy was effective for an appropriate diagnosis and treatment of Boerhaave syndrome.

Endoscopy, Gastrointestinal↗

Experience with endoscopy at Bin Jalawi Hospital K.S.A.

BACKGROUND: Presentation of gastrointestinal disorders may vary in different communities. This study was carried out in town of Hafoof in Eastern zone of Saudi Arabia. Purpose of the study was to observe pattern of presentation, age, sex, smoking status, haemoglobin levels, serological markers for hepatitis, endoscopic findings, histopathology, presence of H. Pylori or otherwise in biopsy materials taken during the endoscopic procedures in patients undergoing endosopic examinations. Findings of 230 endoscopies are presented. METHODS: All patients who underwent endoscopy in Bin Jalawi Hospital KSA, between December 1999 and September 2001 were included in the study. Data regarding above mentioned features was collected. Patients under went gastroscopy, colonoscopy and injection sclerotherapy. Biopsies were taken and histopathological studies were carried out. RESULTS: Data of 187 gastroscopies, 12 sclerotherapy sessions and 31 sigmoidoclonoscopies is presented. Antral Gastritis was most commonly seen pathology. Gastric and esophageal varices, erosive gastritis, carcinoma oesophagus, duodenitis and oesophagitis were among the other common pathologies. Age of the subjects ranged between 15 and 80 years. Hepatitis B surface antigen was detected in 13 Patients and Hepatitis C antibodies were reported positive in 21 samples. CONCLUSIONS: This data reflects pattern of findings encountered on endoscopies in Hafoof area of KSA, this may assist in comparing the pattern of presentation in this centre with other centers within and outside Saudia.

Adolescent↗

Wireless capsule endoscopy in the diagnostic of small intestine angiodysplasia in chronic uremic patient.

Gastroenteric bleeding due to angiodysplasia (AD) is a relatively common occurrence in patients with end-stage renal failure. Gastric and colon angiodysplasic lesions can be easily revealed by endoscopic procedures, whereas lesions of the small intestine are more difficult to detect. Imaging modalities used in the diagnostic imaging algorithm for the detection of small-bowel AD, include non-invasive methods like enema-helical computer tomography,(99m)Tc-labelled red blood cell scintigraphy, and angiography, and invasive methods such as intraoperative enteroscopy. We report the cases of 3 hemodialysis patients with recurrent episodes of gastrointestinal bleeding, caused by small-bowel AD diagnosed by means of wireless-capsule endoscopy. In all cases, previous gastroscopy and colonoscopy were unrevealing. Wireless-capsule endoscopy consists in swallowing a capsule endoscope (11 mmx27 mm) which contains a miniature video camera, a light source, batteries, and a radio transmitter. Video images are transmitted by means of radio telemetry to aerials taped to the body that allow images to be captured. Moving images from a period as long as 6 h are stored on a portable recorder. Wireless-capsule endoscopy may prove valuable in the assessment of gastrointestinal bleeding in uremic patients with unrevealing results at gastroscopy and colonoscopy.

Adult↗

A new complication from a new technology: what a general surgeon should know about wireless capsule endoscopy.

Wireless capsule endoscopy has revolutionized the diagnostic evaluation of the small intestine and is increasingly used by gastroenterologists. However, complications can occur with this seemingly safe procedure. We report two cases of Crohn's disease in which capsule endoscopy was performed with retention of the capsules. Both patients were taken to the operating room electively after careful preoperative planning to address both the surgical aspect of Crohn's disease and the retained capsule. We reviewed the literature on the use of wireless capsule endoscopy in patients with Crohn's disease and discuss the approach to a new surgical complication.

Adult↗

[Significance of venous endoscopy in the exploration and the treatment of venous insufficiency of the legs].

From a pathophysiological standpoint, the analysis of superficial valve lesions provides arguments in favour of the existence of early reflux and widens the role of valves beyond a simple antireflux system. All valves are not the same. Study of their topography in relation to collaterals and perforators enables definition of their role and of the origin of preferential hemodynamic circuits. Therapeutically, the first indications of venous endoscopy were in the visual control of deep venous thrombectomy, then in the preparation of saphenous bypasses in situ. It enables confirmation of the devalvulation of a segment of long saphenous and obstruction of afferent collaterals without an incision, by the endoscopic insertion of "micro-umbrellas". In addition, endoscopy can be used to identify incompetent deep valves suitable for valvuloplasty. In the superficial venous system, endoscopy offers a third dimension in the identification of varicosities in complex zones, such as the popliteal fossa. Furthermore, the development of a system for the endoscopic obliteration of superficial veins (ligatures, laser, umbrellas, chemical glue) could simplify the treatment of varicose veins.

Endoscopy↗

[Effect of nasal endoscopy-assisted adenoidectomy on the development of pediatric chronic sinusitis and otitis media with effusion].

OBJECTIVE: To discuss the effect of nasal endoscopy-assisted adenoidectomy with debrided on the development of pediatric chronic sinusitis and otitis media with effusion. METHOD: Fifteen cases of hypertrophied adenoid with pediatric chronic sinusitis and/or otitis media with effusion were treated with nasal endoscopy-assisted adenoidectomy and medicines followed. RESULT: No remainder of adenoid was left, no complication occurred and snoring disappeared in all patients. Pediatric chronic sinusitis and/or otitis media with effusion recovered with medicines after adenoidectomy. CONCLUSION: Nasal endoscopy-assisted adenoidectomy with debrided was an minimally invasive and effective treatment for hypertrophied adenoid, as well as contributed to the development of pediatric chronic sinusitis and otitis media with effusion.

Adenoidectomy↗

[Autofluorescence endoscopy for diagnosing early laryngeal cancer and its precursor lesions].

OBJECTIVE: To assess autofluorescence endoscopy in the diagnosis of early laryngeal cancer and its precancerous lesions. METHODS: Seventy five patients suspected of having precancerous or cancerous lesions were examined with autofluorescence endoscopy (filtered blue light 380460 nm) under microlaryngoscopy. Autofluorescence pictures were taken with high-solution CCD-camera for analysis, diagnosis and storage, to compare with histologic results. RESULTS: Normal laryngeal mucosa with no visible alteration and mild hyperplasia displayed the typical bright green fluorescence signal, and the areas with moderate dysplasia, severe dysplasia or carcinoma in situ, microinvasive carcinoma and infiltrating carcinoma all showed a marked change in fluorescence to red or violet. Thus, autofluorescence enables to distinguish between benign hyperplastic laryngeal lesions (n =30) and precancerous epithelium (n =45) with a sensitivity rate of 97.8%, and specificity rate of 86.7%. False-negative results (n = 1) were caused by extreme hyperkeratosis, and false positive (n = 4) were cases with scarring or inflammation. CONCLUSIONS: Autofluorescence endoscopy is a less invasive method of diagnosing laryngeal cancer and its precursor, which can be manipulated easily and has high sensitivity. But there are considerable false-positive rates.

Adult↗

[Long term follow up of laser surgery under micro-endoscopy for laryngeal carcinoma].

OBJECTIVE: To observe the long term curative effect for laryngeal carcinoma treated with CO2 laser under micro-endoscopy. METHOD: Twenty cases of laryngeal cancer were treated by CO2 laser under micro-endoscopy. All patients were followed up at least 5 (5-8) years by phone, letters or clinical review. RESULT: During 5 to 8 years following up, one patient died of recurrence 1 year later. Another was operated on with partial laryngectomy due to local recurrence 2 years after laser surgery. The third one was operated with selective neck dissection because of neck metastasis 5 years later. Other 17 cases were alive without recurrent signs. The 5 years total cure rate was 85% and survival rate was 95%, the 5 years local recurrence rate was 10% and the neck metastasis rate was 5%. All survivals had normal breath and good phonation. Among them 8 resumed their daily works, 5 were used to do house works and 4 did them sometimes. CONCLUSION: T1 and earlier glottic or supraglottic cancers are indications of laser surgery under micro-endoscopy. Its 5 years survival rate as well as live quality were satisfactory and proved the method to be a choice of treatment for earlier laryngeal carcinoma.

Adult↗

Sedationless upper endoscopy.

The use of sedation with peroral passage of conventionally sized endoscopes for upper endoscopy is the standard practice for most endoscopists in the United States. The administration of sedatives requires time-consuming and resource-intensive patient monitoring, has substantial cost, and can produce side effects and rare complications. Ultra-thin videoendoscopes (outer diameter less than 6 mm) have been developed, can easily be passed transorally or transnasally without sedation, and have been shown to be well tolerated and accurate. Unsedated upper endoscopy can provide an efficient, cost-effective alternative to standard endoscopy, should be useful for endoscopic screening, and can be offered as an option to conventional sedated examination.

Endoscopes, Gastrointestinal↗

Sedationless upper endoscopy.

The use of sedation with peroral passage of conventionally sized endoscopes for upper endoscopy is the standard practice for most endoscopists in the United States. The administration of sedatives requires time-consuming and resource-intensive patient monitoring, has substantial cost, and can produce side effects and rare complications. Ultra-thin videoendoscopes (outer diameter less than 6 mm) have been developed, can easily be passed transorally or transnasally without sedation, and have been shown to be well tolerated and accurate. Unsedated upper endoscopy can provide an efficient, cost-effective alternative to standard endoscopy, should be useful for endoscopic screening, and can be offered as an option to conventional sedated examination.

Endoscopes, Gastrointestinal↗

[Double-balloon endoscopy for the diagnosis and treatment of small intestinal disease: an initial experience from 25 examinations].

UNLABELLED: Until recently, only the proximal small bowel was accessible for diagnostic and therapeutic endoscopy. Endoscopic evaluation of this organ has often required open laparotomy with surgically assisted passage of the endoscope through the intestine. Recently, Yamamoto et al have developed a new method, double-balloon endoscopy (DBE) that allows high-resolution visualization and therapeutic interventions in all segments of the GI tract. Our aim was to report our early experience with the Fujinon EN-450 T5 therapeutic double-balloon endoscope. PATIENTS AND METHODS: Between August 2005 and March 2006, 25 DBE was conducted in 23 consecutive patients (M/F: 13/10, age: 51.8 +/- 16.5 years) presenting at our tertiary referral hospitals (17 and 4 patients from the oral or the anal route, respectively; 2 patients from both). All procedures were done by i.v. anesthesia, at our outpatient clinic. After the procedure, the patients were monitored in a recovery room for at least 4h before discharge. RESULTS: The main indication for DBE was suspected small-bowel GI bleeding (11), diagnosis or complications of IBD (7), polyposis syndrome (3), stenosis (1) and insertion of jejunal catheter in one case. Twelve out of 22 patients (54.5%) had a small-bowel finding, with 16 of 22 (72.7%) of the patients having a more accurate diagnostic input. The average insertion length was app. 165 cm (range 50-350 cm, SD 97). Patients' tolerance of the procedure was excellent. No severe complications were recognized. CONCLUSIONS: Based on our limited experience double-balloon enteroscopy is a safe and useful method to evaluate and treating small bowel disease in selected patients, including patients with suspected small-bowel strictures, in whom capsule endoscopy is contraindicated.

Adult↗

[Endoscopy-assisted internal fixation of ramus and subcondylar fracture].

OBJECTIVE: To investigate clinical application of endoscopy-assisted internal fixation of ramus and subcondylar fractures. METHODS: In 11 patients with mandibular ramus and subcondylar fractures, endoscopy-assisted internal fixations with titanium plates were performed using micro-angular drill and screwdriver. RESULTS: All of the patients showed no visible facial scars. Orthorpantography and three dimensional reconstructions of spiral CT scan demonstrated that all fractures were healed 1 to 15 months after operation. Slight malocclusion existed in 1 case and slight limited mouth openings were found in 2 cases. CONCLUSIONS: Endoscopy-assisted internal fixation of mandibular ramus and subcondylar fracture avoided visible facial scars and the risk of facial nerve damage, it is, therefore, a minimally invasive and effective procedure.

Adult↗

[Tooth injuries during general anesthesia, oral endoscopy and vibro-massage].

It is generally recognized that dental injury during and after tracheal intubation is a significant problem. Damage may occur during oro-tracheal intubation, oral endoscopy or seismotherapy. The incidence was reported in a study conducted in the contentious department of Lyon hospitals, in France, from 1978 to 1988. Results confirm that damage is relatively common and that the majority of damaged teeth (67%) were known to have been previously restored, or weakened through periodontal disease prior to the damage occurring. Maxillary incisors were the most frequently injured teeth. Fracture of crowns and roots of natural teeth (44,8%), followed by partial luxation (20,8%) and avulsion (20,8%) were the most common injury. Several cases are presented which reveal the clinical value of dental damages that occur during orotracheal intubation, oral endoscopy or seismotherapy. Besides dental or gingival complications can appear immediately but also after a few days or weeks. Some of the most recent development in dental therapy such as the butterfly bridge, titanium implants and porcelain laminate veneers are described. Tooth protective guards must be put into widespread use. Legal implications of dental lesions occurring during oro-tracheal intubation, oral endoscopy or seismotherapy are presented.

Anesthesia, Dental↗

[The terminal ileum and chronic diarrhea: endoscopy, histology and parasitology].

In 53 patients with chronic diarrhea ileoscopy was done following colonoscopy. Beside the microscopic examination, terminal ileum biopsies and mucosal smears were also performed. Endoscopy of the terminal ileum was abnormal in eight patients (15.1%); biopsy itself was diagnostic in 22 patients (41.5%): primary bile acid malabsorption with mucosal atrophy and reduced retention of 75ScHCAT (10), mucosal atrophy after cholecystectomy (4), Crohn's disease (6), backwash ileitis in ulcerative colitis (1), and postirradiation ileitis (1). Biopsies were normal but mucosal smear indicated the cause of diarrhea in a further 10 patients: giardiasis was found in 7, and candidiasis in 3 patients. All in all, endoscopy, biopsy and mucosal smear of terminal ileum showed a sensitivity of 58.5%. In 38 patients in whom laboratory, roentgenologic and endoscopic investigation failed to establish the etiology of diarrhea, the sensitivity of ileoscopy itself was 0%, of ileoscopy with biopsy 36.8% and ileoscopy with biopsy and mucosal smear 47.4%. We conclude that endoscopy, biopsy and mucosal smear of the terminal ileum are indicated in the investigation of patients with chronic diarrhea.

Adult↗

[Sedation in upper gastrointestinal endoscopy].

Sedation in connection with oesophago-gastro-duodenoscopy is carried out in various ways. The investigation may be carried out with surface anaesthesia in the pharynx in well-informed and mentally stable patients but accept of renewed endoscopy is increased significantly when sedation is employed. Patients with an absolute requirement for sedation may be selected possibly employing a brief personality test. Employment of diazepam is extensively employed but diazepam interacts with cimetidin among other drugs, has a relatively long half-life and can cause secondary sedation. Midazolam has a more rapid effect, a briefer half-life, provides deeper sedation and results in more amnesia than diazepam. The oxygen tension decrease during endoscopy regardless of the sedative employed. Other sedatives, opioids, atropin or anaesthetics are not indicated under normal circumstances. Sedation can be abolished immediately after endoscopy with the bendzodiazepin-antagonist, flumazenil.

Anesthesia↗

Problems of gastrointestinal endoscopy in Italy.

The authors discuss some aspects of Gastrointestinal Endoscopy in Italy emphasizing, in accordance with other countries, the importance of preventing the separation of Gastrointestinal Endoscopy and Gastroenterology. An endoscopist should be a gastroenterologist capable of clinically assessing endoscopic results and not just an individual providing a technical service. In a hospital organization, excessive diffusion of the method in small hospitals should be avoided and the more complex techniques should be concentrated in the Gastroenterology and Gastrointestinal Endoscopy Departments in order to guarantee the quality of care and patient safety. Great attention must be given to the training of endoscopists and an adequate preparation of the nursing staff in also important.

Endoscopy, Gastrointestinal↗

[Gastric polyps: role of endoscopy].

Elster's classification differentiates epithelial gastric polyps on the basis of cells origin and relative tendency to change into a malignancy. Out of 3.920 endoscopy of upper digestive tract during the last 10 years, we found 41 gastric polyps, 50% asymptomatic. Endoscopic polypectomy were performed in 61% of cases, without any complication. The other 39% were followed-up and/or surgically resected, according to the results of biopsy. Endoscopy is mandatory for detection of lesions often asymptomatic and histological study of surrounding gastric mucosa. Small polyps must be treated by radical endoscopic polypectomy. If they are too big for endoscopic polypectomy, it's well advised and safer to perform periodic biopsy for hyperplastic type and a surgical resection for adenomatous ones. The detection of intestinal metaplastic or malignant changes beyond basal membrane suggests a resection both subtotal or total according to topography of the lesions. In conclusion the role of endoscopy is well defined in order to clarify histological attributes of gastric epithelial polyps and surrounding mucosal areas. More restricted is its role in the treatment of these lesions.

Adult↗