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At least 1,333 records · Page 74Linked to original sources
PubMed1961

Preserving the sterility of surgical dressings wrapped in paper and other materials.

Materials for wrapping surgical dressings were studied by a method which measured the recontamination rate in packs stored for periods of up to several weeks. Of the materials tested a thick crêpe paper was better than calico and balloon cloth fabrics. Dressings wrapped in paper were not significantly contaminated after storage in dusty places for periods of up to three weeks. For added protection during handling and for convenience in transport and storage, paper packs may be sterilized and kept in paper-lined cartons. The shelf life in good storage conditions would be many weeks at least.

Bandages↗
PubMed2005

Informed consent should be obtained from patients to use products (skin substitutes) and dressings containing biological material.

BACKGROUND: Biological products (tissue engineered skin, allograft and xenograft, and biological dressings) are widely used in the treatment of burns, chronic wounds, and other forms of acute injury. However, the religious and ethical issues, including consent, arising from their use have never been addressed in the medical literature. AIMS: This study was aimed to ascertain the views of religious leaders about the acceptability of biological products and to evaluate awareness among healthcare professionals about their constituents. METHODS: The religious groups that make up about 75% of the United Kingdom population were identified and a questionnaire on 11 biological products was sent to its leaders. Another questionnaire concerning 17 products (11 biological and 6 synthetic dressings) was sent to 100 healthcare professionals working in seven specialist units in the UK. RESULTS: All religious leaders (100% response rate) replied, some after consultation with international bodies. Among them, 77% said that patients should be informed of the constituents of the biological products and consent obtained. Some leaders expressed concerns about particular products including the transmission of viral and prion diseases, cruelty to animals, and material derived from neonates. None of the healthcare professionals (73% response rate) surveyed knew the constituents of all the products correctly. CONCLUSION: Ignoring religious sensitivities and neglecting consent in the usage of biological products could have very serious implications, including litigation. Hospitals and manufacturers should take immediate measures to enlighten healthcare professionals of the constituents of these products so that they can obtain informed consent from patients.

Attitude to Health↗
PubMed1991

Factors influencing dressing performance after stroke.

Sixty consecutive patients with a diagnosis of stroke were assessed using the Nottingham stroke dressing assessment as well as a series of physical and cognitive assessments. Generally the items of clothing worn on the lower half of the body were significantly correlated with the physical assessments and the items of clothing worn on the upper half were significantly correlated with the cognitive assessments. These results support other studies which suggest that motor recovery and perceptual abilities are important determinants of dressing ability.

Activities of Daily Living↗
PubMed1991

Third molar surgery: the effect of primary closure, wound dressing and metronidazole on postoperative recovery.

One hundred and forty eight patients with bilateral symmetrically impacted lower third molars entered a clinical crossover trial to compare the effects on postoperative recovery of a Bismuth Iodoform Paraffin Paste (BIPP) socket dressing, primary closure using a resorbable suture (Softgut) and to ascertain if prophylactic metronidazole influenced the outcome. The results reaffirm the surgical principle that contaminated surgical wounds such as third molar sockets are best kept open with a dressing. Attempts at primary closure should be resisted if there is no intention to prescribe antibiotic cover. However, if a suitable antibiotic is taken then primary closure using a resorbable suture can be carried out with confidence. This may reduce the need for outpatient follow up.

Acetaminophen↗
PubMed1977

Pressure dressings and postangiographic care of the femoral puncture site.

Consecutive patient records (900) were reviewed to determine the incidence of local complications following the use of pressure dressings for femoral puncture. The authors found an overall complication rate (0.44%) which was less than that found by others (1%). No statistically significant differences were found in local complication rates between hypertensive (0.56%) and normotensive (0.42%) groups. No advantage was found in the postangiographic application of pressure dressings.

Angiography↗
PubMed2003

Management of drug rash with eosinophilia and systemic symptoms (DRESS syndrome): an update.

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rather distinct severe adverse drug reaction characterised by skin rash, fever, lymph node enlargement and internal organ involvement. Our aim was to review the available data regarding the management of this probably underrecognised subset of drug reaction. So far, the only undisputed way to treat severe hypersensitivity reactions is prompt withdrawal of the offending drug. The use of systemic corticosteroids remains controversial. The benefit of therapies aimed at accelerating the elimination of the causative drug deserves further studies. In the absence of a well-established therapy, primary and secondary prevention have a key role in the management of DRESS syndrome.

Anti-Inflammatory Agents↗
PubMed1996

Synthetic wound dressings--evaluation of interactions with epithelial and dermal cells in vitro.

Comparative testing of seven wound dressings (WD) has been performed with human HaCaT keratinocyte and mouse 3T3 fibroblast cultures. To assess biocompatibility, morphologic examinations were combined with cell counting. Supernatants were subjected to measurements of tissue peptide antigen (TPS), soluble intercellular adhesion molecule 1 (ICAM-1), and interleukins (IL-1 alpha, -1 beta, -6). Furthermore, monoxygenation, the reduced glutathione/oxidized gluthathione (GSH/GSSG) ratio and lipid peroxides were determined. Initial morphologic events were noted within the first day of exposure to WD. After 72 h, inhibition of cell growth was observed in the presence of hydrocolloids and hydrogels. The cytochrome-P-450-dependent ethoxyresorufin 0-deethylation rate and the GSH/GSSG ratio were not altered by WD in HaCaT cells. Lipid peroxide generation, IL-1 and ICAM-1 were scarcely detectable. TPS and IL-6 release indicate the presence of an 'activated stage' of keratinocytes and fibroblasts exposed to WD. Peptide release in vivo may contribute to the beneficial effects of modern dressings in the treatment of superficial cutaneous wounds.

3T3 Cells↗
PubMed1992

Modern wound dressings: a systematic approach to wound healing.

The advent of modern wound care management constitutes one of the most innovative applications of medical device technology. The foundation for wound care recent advances has been built upon the developments achieved in polymer technology over the last three decades. New and unique materials have been engineered to provide properties with significant technical and clinical benefits. These new wound care products were made possible by the convergence of three interrelated disciplines: (1) more complete understanding of the underlying principles of dermal wound healing processes, (2) new elastomeric polymers capable of being fabricated into protective dressings, and (3) advances in breathable adhesive technology. The following discussion provides a critical review of the current status of technology and the worldwide opportunities for improved wound management products. Particular attention is focused on the clinical applications of the newer, breathable dressing products, which approximate a temporary synthetic artificial skin.

Bandages↗
PubMed1998

The effects of alginate and non-alginate wound dressings on blood coagulation and platelet activation.

Alginates are used as haemostats in wound dressings. They act as calcium ion (Ca) donors as they contain mannuronic (M) or guluronic (G) groups with a high Ca content. This study compared the effects of calcium and zinc containing alginates and non-alginate dressings on blood coagulation and platelet activation to determine which was the best haemostat. We showed that alginate materials activated coagulation more than non-alginate materials. The extent of coagulation activation was affected differently by the alginate M or G group composition. It was demonstrated that alginates containing zinc ions had the greatest potentiating effect on prothrombotic coagulation and platelet activation.

Alginates↗
PubMedDate not supplied

Oxidized cellulose dressings for persistent bleeding from a superficial malignant tumor.

Persistent bleeding from superficial malignant tumors, although uncommon, can be a major and distressing problem. Management includes frequent skilled dressing changes, correction of clotting abnormalities, and maintaining blood volume by repeated transfusions. We report a case where application of oxidized regenerated cellulose surgical dressing appeared to contribute to successful hemostasis.

Adult↗
PubMed2006

The evidence supporting the use of honey as a wound dressing.

Some clinicians are under the impression that there is little or no evidence to support the use of honey as a wound dressing. To allow sound decisions to be made, this seminar article has covered the various reports that have been published on the clinical usage of honey. Positive findings on honey in wound care have been reported from 17 randomized controlled trials involving a total of 1965 participants, and 5 clinical trials of other forms involving 97 participants treated with honey. The effectiveness of honey in assisting wound healing has also been demonstrated in 16 trials on a total of 533 wounds on experimental animals. There is also a large amount of evidence in the form of case studies that have been reported. It has been shown to give good results on a very wide range of types of wound. It is therefore mystifying that there appears to be a lack of universal acceptance of honey as a wound dressing. It is recommended that clinicians should look for the clinical evidence that exists to support the use of other wound care products to compare with the evidence that exists for honey.

Animals↗
PubMed2006

Development and in vitro evaluation of Chitosan-Eudragit RS 30D composite wound dressings.

The purpose of this research was to design and evaluate chitosan-based films intended for wound dressing application. Required properties for successful wound dressing, such as liquid uptake, vapor and oxygen penetration, bioadhesiveness, and film elasticity, were examined. Water uptake and vapor penetration of the films were determined gravimetrically, while oxygen penetration was determined by Winkler's method. The bioadhesive properties were determined with an in-house pulley system instrument using a pig gut model. Film elasticity was determined with a stretch test using an Instron apparatus. The results showed that pure chitosan films exhibited relatively high liquid uptake and the adsorption tended to decrease with the addition of Eudragit RS 30D. Moisture vapor and oxygen were found to be able to penetrate through all film formulations in comparable amounts. The bioadhesiveness test tended to show lower bioadhesive properties with the addition of Eudragit RS 30D. The formulation containing only chitosan exhibited low elongation of the film at 2 N, but the film elasticity increased with the addition of Eudragit RS 30D. In conclusion, the addition of Eudragit RS 30D could improve a film's mechanical properties but lower its bioadhesiveness.

Acrylic Resins↗
PubMed2003

Patient-controlled sedation using propofol for dressing changes in burn patients: a dose-finding study.

The first change of dressings after skin grafting in burn patients is a source of great anxiety because of pain anticipation and the immediate and first confrontation with the result of skin grafting. We designed this dose-finding study to determine the feasibility and safety of patient-controlled sedation (PCS) using propofol during these procedures. Twenty patients were familiarized with the PCS and asked to use PCS whenever they felt uncomfortable or anxious. Analgesia was provided by a single bolus of morphine IV 15 min before the procedure according to their daily intake. The first 10 patients used a fixed bolus of propofol 0.3 mg/kg and a lockout of 5 min. The degree of sedation was measured using bispectral index (BIS) monitoring. Demands versus delivery of propofol boluses were recorded. Within 1 h after the procedure, pain intensity was evaluated and satisfaction scores obtained from patients and nurses performing the dressing changes. In the first 10 patients, there were no respiratory rates <10 breaths/min, systolic and diastolic blood pressure were within 25% of baseline values, and peripheral saturation stayed more than 94% with additional small flow oxygen via nasal insufflation. There were double the demands than actual deliveries of propofol boluses. The BIS did not show significant decreases of <80 in any patient reflecting an insufficient state of sedation. Because the interim analysis of the efficacy of the PCS setup showed an insufficient state of sedation, a different PCS setup was evaluated in a second group of 10 patients (an individualized propofol bolus, titrated to achieve a significant decrease of BIS or a sleepy state, and no lockout period). The second group of patients showed a more effective sedation, with respiratory and hemodynamic variables being not significantly different from the first group of patients. PCS with propofol is feasible in burn patients and can be used safely. To provide an optimal sedation, we suggest to initially titrate the bolus to achieve a significant decrease of BIS or a clinically effective state of sedation and to abolish the lockout interval.

Adult↗
PubMed2005

Making the most of teams in the mentorship of students.

Community nurses are rightly expected to act as mentors. This role offers students valuable opportunities to gain insight into community care and contributes to the development of future services and the professional growth of individual mentors. There can be tension, however between the demand of nurses' clinical roles and the need to support students. This article identifies ways in which teams can get the most out of mentoring, focusing on the importance of strong clinical leadership and the need for nurses to "own" the mentorship role and to work with other stakeholders. Finally, examples of initiatives from one inner-London trust are offered to demonstrate robust ways of enabling practice-based education.

Community Health Nursing↗
PubMedDate not supplied

Evaluation of a hydrocellular dressing in the management of exuding wounds in the community.

A multicentre clinical trial was conducted to assess the performance and acceptability of a hydrocellular dressing in the management of exuding wounds by community nurses. The study examined ease of use, adherence, patient comfort, conformability and safety in use. Since this article was written, Allevyn hydrocellular dressing has become available on the Drug Tariff.

Adolescent↗
PubMedDate not supplied

Establishing a dressings formulary.

Choices have to be made between the multitude of dressings available, and especially between products with the same characteristics and features. This article describes how to compile, maintain, monitor and review a dressings formulary.

Bandages↗
PubMedDate not supplied

Tegasorb hydrocolloid dressing: advanced formulation.

Tegasorb advanced formulation hydrocolloid dressing from 3M Healthcare can be used on a variety of wounds, e.g. leg ulcers and donor sites. It encourages a moist wound-healing environment and can be used in all stages of wound healing, from black necrotic tissue to the epithelializing wound. Tegasorb is a well-established hydrocolloid dressing that has recently been relaunched as an advanced formulation.

Bandages, Hydrocolloid↗
PubMedDate not supplied

The role of Sterigel hydrogel wound dressing in wound debridement.

An increasing number of hydrogel dressings have become available to the practitioner over the last few years. Sterigel (Seton Healthcare) is the latest to be launched. This dressing is able to donate large quantities of fluid and thereby speed up the debridement of slough and necrotic tissue.

Bandages↗