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At least 1,333 records · Page 74Linked to original sources
PubMed1985

Adenoid cystic carcinoma of the head and neck: a clinical study of 37 cases.

Thirty-seven cases of adenoid cystic carcinoma treated at the Otolaryngologic Clinic of the University of Florence between 1962 and 1979 were studied. The patients were treated with radical surgical excision (20), non-radical surgery associated with radiotherapy (13), or with palliative treatment (4). The aim of this study is to evaluate the course of the disease according to the site and type of operation. Our results show that non-radical surgical treatment associated with radiotherapy seems to give results comparable to those obtained with radical surgery alone.

Adult↗
PubMed1985

Adenoid cystic carcinoma of the vulva with lung metastases. A case report.

The presenting symptoms of adenoid cystic carcinoma of the vulva in a 57-year-old woman were a vulvar mass and pain. The mass was excised locally. The disease recurred in the lung four years later. The patient was treated with several regimens of chemotherapy, without significant effect. She died of pulmonary failure six years after diagnosis.

Carcinoma, Adenoid Cystic↗
PubMedDate not supplied

Adenoid cystic carcinoma of the nasopharynx. Case reports and literature review.

Adenoid cystic carcinoma of the nasopharynx is a rare disease with 34 previously reported cases in the literature. We report three additional cases with clinical presentation, treatment, and outcome. The presenting symptoms were facial pain in one case, middle ear effusion and epistaxis in another, and diplopia in the third. Radiotherapy was administered with relief of symptoms in all three cases. However, two patients with long-term follow-up developed local recurrence as well as distant metastases. The literature review showed that patients with this disease present with symptoms and signs such as insidious onset of facial pain, epistaxis, diplopia, and hearing loss. The final outcome, despite vigorous treatment, was dismal.

Adult↗
PubMed1986

[Adenoid cystic sweat gland cancer].

Two primary adenoid cystic carcinomas of the eccrine sweat glands of the skin are presented. This tumor, first described in recent years, represents the rarest form of carcinoma of the eccrine sweat gland. The tumor demonstrates characteristic histological features and clinically often exhibits slow progression and absence of lymph-node metastases. The most important differential diagnosis to be excluded is metastasis of an adenocarcinoma of an internal organ.

Adult↗
PubMed1986

[Adenoid cystic carcinoma of the head and neck--a clinical study of 27 cases].

Adenoid cystic carcinoma (ACC) is frequently seen in the salivary glands, but may occur at other sites in the head and neck. We report 27 patients with ACC treated at the Department of Otorhinolaryngology, Mie University School of Medicine, for 15 years. The survival rate dropped from 78% at five years to 36% at 10 years. This suggests that the long-term prognosis of ACC is poor. According to Batsakis, we classified ACC according to histopathology and emphasize that the solid cellular pattern had the worst prognosis.

Adolescent↗
PubMed1986

[Adenoid cystic cancer of the breast].

A case of a mammary adenoid cystic carcinoma in a female of 45, is described. The tumour was histologically identical to the salivary gland tumours of the same name.

Breast↗
PubMed1986

[Adenoid cystic carcinoma of the esophagus].

A 56-year-old man was admitted with the complaint of dysphagia. X-ray studies and endoscopy revealed a protruding tumor at the middle third of esophagus. Under the diagnosis of esophageal cancer, subtotal esophagectomy was performed. A Borrmann type I like tumor measuring 6.7 X 3.8 X 2.2 cm was identified on the resected specimen. The surface of the tumor was irregular, nodular and covered with thin compressed esophageal mucosa. The histology of the tumor was consistent with adenoid cystic carcinoma. Incidentally, small foci of invasive squamous cell carcinoma were found adjacent to this tumor. There was no lymph node or remote organ metastasis.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1987

AIDS, otolaryngology and a case of adenoid cystic carcinoma of the parotid arising in a patient with the AIDS-related complex.

The incidence of acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC) is increasing, and as head and neck manifestations of this entity are common it is important that otolaryngologists have an up-to-date knowledge of this condition. In this paper the epidemiological aspects of the disease are reviewed and the head and neck manifestations discussed. An interesting case of adenoid cystic carcinoma of the parotid arising in a patient with ARC is presented.

AIDS-Related Complex↗
PubMedDate not supplied

Isolation of follicular dendritic cells from human tonsils and adenoids. VI. Analysis of prostaglandin secretion.

Follicular dendritic cells (FDC) are able to fix high amounts of immune complexes by C3b or Fc receptors without endocytosis and for long periods of time. In order to determine the function of this retention, we analysed the secretion of prostaglandin E2 (PGE2) by FDC in vitro; indeed, it is well-known that immune complex fixation on cells may induce PGE2 production. FDC were isolated by enzymic digestion of lymph follicles dissected under the biomicroscope from human tonsils or adenoids. Isolated FDC appeared as spherical clusters where they enveloped lymphoid cells with their cytoplasmic extensions. Tests were performed in synthetic culture media or in media supplemented with foetal calf serum. PGE2 production in FDC suspensions was compared to that of lymphocyte or macrophage-enriched populations prepared from the same human tonsils. In all experimental conditions, FDC and macrophage-enriched cell populations produced high levels of PGE2, inversely to lymphoid cell populations. This secretion was inhibited by indomethacin. At the ultrastructural level, we also showed that 3H-arachidonic acid was metabolized in cell membranes of all three cell types. The PGE2 produced in the culture media, according to our experimental conditions, do not influence cell proliferation, as assessed by 3H-thymidine incorporation tests on phytohaemagglutinin-stimulated lymphocytes.

Adenoids↗
PubMed1979

Lymphocytes from adenoid vegetations: proliferative responses in vitro as compared to blood lymphocytes.

Thymidine incorporation by lymphocytes obtained from adenoids (AVL) and blood (PBL) were compared in 27 children undergoing adenoidectomy. Optimal conditions as regards cell number and duration of culture were worked out. The spontaneous thymidine incorporation was higher in PBL than in AVL. In cultures stimulated by polyclonal activators or by PPD, the responses of PBL were higher. The dose-response curves for PBL and AVL after stimulation with killed H. influenzae were different: PBL showed a higher response, the optimal antigen concentration was lower for PBL, and the responsiveness to suboptimal antigen concentrations wash higher in PBL than in AVL.

Adenoidectomy↗
PubMed1985

Isolation of follicular dendritic cells from human tonsils and adenoids. III. Analysis of their Fc receptors.

Follicular dendritic cells (FDC), isolated from human tonsils or adenoids, were tested for their capacity to retain monomeric, aggregated or antigen-bound human antibodies in the absence of serum. FDC retain fluorescein-labelled heat-aggregated human immunoglobulins, but not monomeric ones nor fluorescein-labelled F(ab')2 in monomeric or aggregated form. Ultrastructural observations showed that colloidal gold-labelled monomeric, or antigen-bound, antibodies directed against tetanus toxoid are retained by dendrites and membrane infoldings of FDC but are never located in cytoplasmic vesicles. This retention was inhibited by incubating FDC with unlabelled aggregated or antigen-bound antibodies. When gold-labelled anti-tetanus toxoid antibodies were incubated in the presence of protein-A before the contact with FDC, a strong reduction of their retention occurred. This further suggested the presence of Fc receptors on isolated tonsillar FDC. Endocytosis was not observed in isolated FDC, even after prolonged incubation in presence of labelled immune complexes: their Fc receptors are, thus, not related to a phagocytic activity as they are in macrophages. Simultaneous ultrastructural labelling of Fc and C3b receptors with colloidal gold particles of different sizes did not reveal any clear relations between these two receptors on the surface of FDC.

Adenoids↗
PubMed1987

Pathology of the tonsils and adenoids.

Some conditions of the tonsils and adenoids often present problems in diagnosis for the surgical pathologist. These include variations of normal histologic features, atypical reactive and metaplastic lesions, hamartomas, papillomas, carcinomas, and some types of lymphomas. The reasons for errors in histopathologic diagnosis have been emphasized, and the clinicopathologic features that can help to prevent misdiagnoses are discussed.

Adenoids↗
PubMed1986

Sialadenoma papilliferum of the adenoids in a 2-year-old child.

We report a case of sialadenoma papilliferum arising in the adenoids in a 2-year-old child. The tumor demonstrated papillary and adenomatous proliferations, suggestive of minor salivary gland origin. A review of the literature indicated no reported cases of this neoplasm arising in individuals this young. The location of the growth also appears to be unique. Regular follow-up by endoscopy and computed tomographic scan of the nasopharyngeal area have not revealed recurrence of disease one year after resection.

Adenoids↗
PubMed1972

Adenoid cystic carcinoma of the breast.

Adenoid cystic carcinomas of breast are rarely recorded tumors affording an excellent prognosis. This present report documents three new cases and reviews the literature. Histologic features distinguishing it from cribriform intraductal carcinoma are emphasized.

Adult↗
PubMed1981

[Occlusive adenoids causing cor pulmonale and pectus excavatum in a child (author's transl)].

In a Child respiration was impaired already during infancy by occlusive adenoids causing pectus excavatum, cardiomegaly with signs of right ventricular and right atrial hypertrophy, hepatomegaly and dystrophy. The child showed psychological injury as well. After adenectomy these symptoms gradually disappeared. The cardiorespiratory syndrome by obstruction of the upper airways demands active surgical therapy since it may lead to right ventricular failure and pulmonary edema.

Adenoidectomy↗