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A radiologic study of tuberculosis of the abdomen (gastrointestinal tract).

The roentgenologic features of 160 cases of tuberculosis of the abdomen are reviewed. The 3 standard examinations of the gastrointestinal tract (plain film abdominal roentgenography, barium meal and follow-through studies, and barium enema examinations) are required to provide useful pointers towards the diagnosis. In plain film roentgenography of the abdomen, the triad of ascites, absence of gas shadows in the right iliac fossa, and segmental dilatation of the terminal ileum demonstrates features which are very suspicious of intestinal tuberculosis. In the barium meal studies showing disordered small bowel patterns, tuberculosis of the abdomen should be considered when this pattern is associated with fixation of bowel loops on supine and erect roentgenograms, spiculation and the presence of multiple strictures in the small bowel. Although the duodenojejunal and ileocecal regions are the commonest sites involved, lesions are not confined to these sites alone, but may also involve any part of the alimentary canal such as the esophagus and the small and large bowel. However, no anorectal lesions were encountered in this study.

Ascites↗

Atypical mycobacterial cervical lymphadenitis associated with Sweet's syndrome.

We report the case of a 52-year-old woman with a non-tuberculous (atypical) mycobacterial cervical lymphadenitis, caused by Mycobacterium fortuitum, in association with Sweet's syndrome. The cervical lymphadenitis was resistant to medical treatment, and the Sweet's syndrome occurred intermittently. Systemic steroid treatment was required to control the cutaneous symptoms.

Fatal Outcome↗

Clinical significance of nontuberculous mycobacteria. A bacteriological survey of Swedish strains isolated between 1973 and 1981.

An account is rendered of mycobacteria other than Mycobacterium tuberculosis isolated from specimens sent for culture during 9 years. The possible etiological significance of these bacteria was estimated from clinical data and the degree of bacterial growth. Pulmonary infection was the most common nontuberculous manifestation in the adults. In about 50% of the patients with slowly growing mycobacteria in their respiratory tract, these bacteria were considered to be an etiological factor. This applied to the species of the M. avium-intracellulare (MAI) complex and M. xenopi. M. Kansasii, a common cause of lung disease in many other countries, was rarely isolated. The corresponding figure for the rapidly growing mycobacteria belonging to the M. fortuitum-chelonei complex was 15%. These patients were all severely debilitated by other diseases. Lymphadenitis was the most common nontuberculous infection in children, but occurred only in children not vaccinated with BCG. Bacteria of the MAI complex was the predominating cause. Lung infection caused by nontuberculous mycobacteria did not occur in children.

Adolescent↗

Tuberculosis in homosexual men with HIV disease.

In a 1-year period 4 cases of disseminated tuberculosis were seen among homosexual men with HIV infection. In 3 of the cases tuberculosis was the initial manifestation of defective cell mediated immunity. It is concluded that tuberculosis must be considered in any anti-HIV positive patient presenting with fever of unknown origin.

AIDS-Related Complex↗

Extrapulmonary Tuberculosis among Somalis in Minnesota.

To analyze extrapulmonary tuberculosis in Somalis living in Minnesota, we reviewed surveillance and public health case management data on tuberculosis cases in ethnic Somalis in Minnesota from 1993 through 2003. The presence of these recent immigrants substantially affects the local epidemiology and clinical manifestation of tuberculosis.

Adolescent↗

Clinical manifestations and diagnosis of extrapulmonary tuberculosis.

Since the diagnosis of extrapulmonary tuberculosis (EPT) is largely depended on the physician's suspicion in respect of the disease, we believed that it would be worthwhile to scrutinize the clinical characteristics of EPT. Thus, here we present retrospectively evaluated clinical manifestations of patients who were diagnosed as EPT cases in a tertiary referral care hospital. Medical records of 312 patients, diagnosed as having EPT at Yongdong Severance hospital from January 1997 to December 1999, were reviewed retrospectively. In total 312 patients, 149 (47.8%) males and 163 (52.2%) females aged from 13 years to 87 years, were included into this study. The most common site of the involvement was pleura (35.6%). The patients complained of localized symptoms (72.4%) more frequently than systemic symptoms (52.2%). The most common symptom was pain at the infected site (48.1%). Leukocytosis, anemia, and elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were found in 12.8%, 50.3%, 79.3% and 63.1% of the patients, respectively. Twenty-four percent of the patients had underlying medical illnesses such as, diabetes mellitus or liver cirrhosis, or were over 60 years old. In 67.3% of patients, tuberculosis was suspected at the initial visit. However, tuberculosis was microbiologically proven in only 23.7% of the patients. The time interval from the symptom onset to the diagnosis varied, with the mean duration of the period 96 days. Pulmonary parenchymal abnormal lesions were found in 133 patients (42.6%) on chest radiographs. EPT has a wide spectrum of clinical manifestations, so it is difficult to diagnose it. Based on our studies, only 11.2% of the patients were confirmed as EPT. So it is important that the physician who first examines the patient should have a high degree of suspicion based on the chest radiography, localized or systemic symptoms and several laboratory parameters reviewed in this study.

Adolescent↗

[Tuberculous chylothorax: case report and review of the literature].

Chylothorax is an unusual manifestation of tuberculous disease. Anecdotal cases of chylothorax due to Mycobacterium tuberculosis have been reported in the literature. We describe a case of tuberculous chylothorax and review the previously published cases. None of these cases was diagnosed by the application of polymerase chain reaction in pleural effusion. This test applied to different specimens has shown high specificity and sensitivity; for this reason, the routine use of this test, on pleural effusion, could be very useful, quick, and few aggressive in the diagnosis of tuberculous chylothorax, especially when chest X-ray is normal.

Adult↗

Tuberculosis in indigenous Australians.

A comparative study of tuberculosis in Aboriginal and white Australians is presented. There is a much higher prevalence of disease in the Aboriginal population than in the white. From a study of the clinical features and response to treatment in paired cases, disease in the Aboriginal is found to be more acute, more extensive and more frequently non-pulmonary. As this disease pattern is unfamiliar to many Australian doctors, tuberculosis should enter into the differential diagnosis of all ill Aborigines.

Acute Disease↗

Disseminated tuberculosis: still a diagnostic challenge.

Disseminated tuberculosis is notoriously difficult to diagnose and, with the decrease in tuberculosis incidence in Australia, familiarity with its manifestations has dwindled. We describe four bacteriologically proven cases which illustrate the range of presentations and diagnostic difficulties. Surprisingly, immunosuppressive therapy need not cause rapid deterioration. Disseminated tuberculosis should be considered in any patient with multisystem illness who is at risk of tuberculosis, particularly if born overseas. In the absence of confirmatory results, a prompt therapeutic trial may be life-saving.

Adult↗

Scrofuloderma neck with chest wall abscess.

Cutaneous tuberculosis (TB) is among the uncommon varieties of tuberculosis but it is also on the rise, commensurate with the general resurgence of the disease. A case of scrofuloderma of neck with tuberculous abscess of anterior chest wall is, hereby, reported. The patient presented with a non-healing ulcer of neck with swelling of anterior chest wall, which responded to antituberculous treatment. This complication of scrofuloderma neck is very rare and should be kept in mind in the differential diagnosis of such lesions.

Abscess↗