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[A review of the nutritional management plans in the member states of the European Union].

Obesity has reached epidemiological proportions in Europe and the burden of diseases attributable to nutrition is substantial. Under the impetus of the World Health Organisation (WHO), member states have been urged to develop national action plans for nutrition and physical activity. This study describes what has been done in terms of nutrition policy at national level in the member states of the European Union right before its enlargement in 2004. It is a critical review of publicly available policy documents on nutrition and physical activity. The background idea was to assist the initiative of the Belgian food industry to play a proactive role in the development of a Belgian nutrition action plan. At the time of writing, in total six out of the fifteen EU member states namely Sweden, Finland, Denmark, France, the Netherlands and the United Kingdom, reported to have an operational national nutrition plan. By the end of the year 2004, another four countries are expected to have their plan finalised. In line with WHO guidelines, all nutrition plans in this study acknowledge the importance of a multidisciplinary approach and promote stakeholder involvement at some point. Most of the plans however, do not elaborate on their specific role and strategies that will be used to do so. It seems that stakeholder mobilisation is largely restricted to the implementation phases. All operational nutrition plans envisage reducing social disparities. Long-established vulnerable groups in society such as pregnant women, children and elderly are targeted. Considerable variability was observed for nutritional objectives and dietary recommendations between the different countries. Nutrition surveillance and monitoring activities seem to vary considerably between the different action plans. None of the countries except Denmark documents the theoretical foundations and development process of their nutritional surveillance system. National nutrition policy in Europe is clearly in a state of flux and the centre of gravity seems to move away from Scandinavia. Although the importance of nutritional surveillance, comprehensive approach to nutritional problems and stakeholder involvement is recognised by the action plans, the rationale, justification and mechanisms for it is vaguely described. Our findings call for increased efforts to strengthen the evidence base of public health nutrition policy. To achieve this however, systematic evaluations and proper reporting of which health and nutrition promotion strategies work in the different countries in the EU are urgently needed.

European Union↗

Current trends in the surgical treatment of solitary parathyroid adenoma. A questionnaire study from 53 surgical departments in 14 countries.

Current trends in the surgical treatment of primary hyperparathyroidism due to solitary parathyroid adenoma were evaluated in a questionnaire study. Response was obtained from 53 departments highly active in endocrine surgery in 14 countries (response rate 95%). Intraoperative histologic examination is widely (70%) regarded as necessary, but utilized more in North America and Scandinavia (87%) than elsewhere (45%). Intraoperative fat staining is used in one-third of the departments. Excisional biopsy including one whole gland is preferred by 32% to multiple incisional biopsies. Gross inspection of three normal parathyroid glands without histologic identification is favoured in 21% of the departments, while 31% prefer bilateral exploration and incisional biopsy. When an adenoma is found on the first side to be explored, 17% advocate bilateral exploration with incisional biopsy of all three normal glands, whereas unilateral exploration with excisional or incisional biopsy of the ipsilateral normal gland is preferred by a similar percentage.

Adenoma↗

[Inheritance in lymphoproliferative disorders].

Lymphoproliferative disorders, especially chronic lymphocytic leukaemia (CLL), non-Hodgkin's lymphomas, Hodgkin's lymphoma and multiple myeloma are regarded as a hereditary entity with pleiotropic clustering in families, although the genuine alleles have not been found so far. The world-wide highest incidence of CLL and the existence of a systematic cancer registration since 1943 make Denmark a perfect place for epidemiological and genealogical investigations in the search for the genetics of the lymphoproliferative disorders. In Scandinavia, we see no signs of anticipation but marked linkage between parents and children, where the combination CLL in parent and CLL in child is more predominant than CLL in parent and a child with any other type of lymphoproliferative disorder. This same conservative pattern is also seen in parent-children transportation of non-Hodgkin's lymphomas and Hodgkin's lymphoma. That no certain linkage to other cancers can be significantly detected is discussed. A non-Mendelian mode of inheritance seems not unlikely in the familial clustering of the lymphoproliferative disorders.

Denmark↗

[Therapeutic effects of risedronate on Paget's disease of bone].

Paget's disease of bone (PDB) is a chronic disorder characterized by focal abnormalities of bone turnover. The characteristic feature of PDB is excessive osteoclastic bone resorption coupled to increased and disorganized bone formation. Although PDB is rare in Japan, it is quite common in most European countries, except for Scandinavia. The recommended regimens for bisphosphonates use in various parts of the world. Calcitonin and etidronate are approved by the Ministry of Health, Labour and Welfare in Japan to treat PDB. Risedronate is currently under development for use in the treatment of PDB in Japan.

Aged↗

Mapping VIPS concepts for nursing interventions to the ISO reference terminology model for nursing actions: A collaborative Scandinavian analysis.

The aims of this study were to analyze the coherence between the concepts for nursing interventions in the Swedish VIPS model for nursing recording and the ISO Reference Terminology Model for Nursing Actions and to identify areas in the two models for further development. Seven Scandinavian experts analyzed the VIPS model's concepts for nursing interventions using prototypical examples of nursing actions, involving 233 units of analyses, and collaborated in mapping the two models. All nursing interventions in the VIPS model comprise actions and targets, but a few lack explicit expressions of means. In most cases, the recipient of care is implicit. Expressions for the aim of an action are absent from the ISO model. By this mapping we identified areas for future development of the VIPS model and the experience from nursing terminology work in Scandinavia can contribute to the international standardization efforts.

Cooperative Behavior↗

[Sudden infant death in Norway--does bedding play any role?].

During the last decade the occurrence of the sudden infant death syndrome (SIDS) has increased in Norway, which now has the highest incidence in Scandinavia. A factor which might explain the differences between countries is discussed. Use of different kinds of bedding in the different Nordic countries seems to correspond to differences in the incidence of sudden infant death syndrome. Temperature disturbance has been suggested earlier as a possible aetiological factor and the present hypothesis seems to be supported by results showing the effects of temperature on the syndrome.

Bedding and Linens↗

Anthelmintic resistance in nematode parasites of sheep in Denmark with special emphasis on levamisole resistance in Ostertagia circumcincta.

This study was undertaken to elucidate the presence of anthelmintic resistance in nematode parasites of sheep in Denmark. Twenty two flocks of sheep were selected for Faecal Egg Count Reduction (FECR) tests, based on a prior history of either the same anthelmintic, or anthelmintic class having been used 3 times or more over the previous 5 years. Evidence of anthelmintic resistance was detected in 7 flocks. Two flocks showed FECR of 88% and 94% after treatment with thiabendazole, FECR of another 2 were 90% and 94% following treatment with fenbendazole. Three flocks showed FECR of 73%, 89% and 94%, respectively following the use of levamisole. Ostertagia circumcincta was isolated from 1 of the latter flocks and subjected to an in vivo controlled slaughter assay. Following treatment with levamisole at the recommended dose rate of 7.5 mg/kg, FECR was 44.5% and worm counts were reduced by 67.7%. These results were further substantiated by an in vitro egg hatch paralysis assay and by measuring pepsinogen levels in treated and non-treated lambs. This is the first instance of anthelmintic resistance in sheep nematodes in Scandinavia.

Animals↗

Human ochratoxicosis in France.

The prevalence of human ochratoxicosis in France is being determined using serum and plasma collected from apparently healthy people. The analytical method is based on the partition coefficient of ochratoxin A in aqueous and organic solvents, according to pH. High-performance liquid chromatography and spectrofluorimetry are used for detection and quantification (limit of detection, greater than 0.2 ng/ml). The presence of ochrotoxin A is confirmed by the action of carboxypeptidase to yield ochratoxin alpha or by derivatization of ochratoxin A with boron trifluoride. The significance of the interim values obtained and the number of positive samples is discussed. A comparison with the distribution of known values in Germany and Scandinavia could be helpful in risk assessment with a view to prevention.

Chromatography, High Pressure Liquid↗

[Various necessary steps in clarification of relationships between health care science, medical science and nursing science].

The article asserts that a scientific discipline is defined by both its object of research or knowledge (domain) and its specific or adequate method. An appropriate definition should fulfill other necessary conditions implicit in certain fundamental rules of definition, e.g., a definition should not be too narrow or too broad. It should also respect well established uses of language, in which the concept to be defined may already have a given meaning. In Scandinavia there are three words used for the Science of Health Care. "Vårdvetenskap" e.g., is used both in Sweden and Finland. In Finland it is used to convey the view that care is essential to Man, and a holistic concept of Man/Health. So demarcated, Vårdvetenskapen complements Medicine which ontologically reduces Man to biochemistry and sickness to disease. To fulfill this function the Science of health Care should be humanistic and interdisciplinary, and not purely empirico-positivistic like Medicine.

Health Occupations↗

A century of alcoholism conferences: unchanging themes.

Modern conferences on alcoholism receive research papers and stimulate multidisciplinary discussion, but this is not new, similar events took place 100 years ago. The published proceedings of Chester's conference of 1895 are reviewed and compared with recent conferences. Subjects then included alcohol's effect on the foetus, particular facets of women's drinking and increased availability in grocer's shops, the young and evaluation of educational programmes, alcohol in the workplace, long term control studies on alcoholics, laboratory studies on reaction time, attitude of the popular press, effects of restrictions in outlets and hours and lessons to be learnt from such in Scotland, and political and legislative remedies including evidence from Scandinavia. A full knowledge of earlier research and experience may modify current thinking and prevent simple repetition of previous endeavour.

Alcoholism↗

Transfusion in the exsanguinating Jehovah's Witness patient--the attitude of intensive-care doctors.

The attitude of a Jehovah's Witness patient refusing a blood transfusion during an exsanguinating episode can raise important ethical problems. Various ethical principles, including the patient's autonomy, the sanctity of life and the dignity of the medical profession can be confronted. A total of 242 doctors, members of the European Society of Intensive Care Medicine, answered a questionnaire indicating that 63% would transfuse in those circumstances. However, 26% would never inform the patient about this. Only 45% considered the blood transfusion as appropriate, of whom 25% were unable to define the best option. Doctors from France and Italy more commonly transfuse while those from The Netherlands, the United Kingdom and Scandinavia more commonly withhold transfusion. These data stress the need for a definition of the appropriate medical attitudes towards the patient refusing blood transfusion.

Attitude↗

Epidemiology and early detection of colorectal cancer.

Further information consolidating the roles of dietary fat and fiber and physical inactivity in colorectal carcinogenesis has been published in the year under review. A large cohort study identified animal fat as the most important dietary risk factor, and a meta-analysis of fiber supported the role particularly of vegetable fiber in protection. An important population-based study in Scandinavia identified age at onset of ulcerative colitis as a factor independent of length of follow-up; risk at 35 years after onset was 40% for those with early-stage onset. An update at the St. Mark's Hospital, London, surveillance experience offers measured support for endoscopic screening for dysplasia and curable cancer. A unique paper from Japan defines a relative risk of cancer after polypectomy of 2.3. A case-control study of occult blood screening showed that the sensitivity of guaiac testing for fecal occult blood (Hemoccult, Smith Kline Diagnostics, CA) for asymptomatic colorectal cancer is just under 50%. Cost-benefit modeling suggests that annual occult blood testing and 3- to 5-yearly flexible sigmoidoscopy are optimal.

Colorectal Neoplasms↗

[Exchange transfusion in cases of falciparum malaria].

Malaria is diagnosed in 50-70 patients each year in Norway. Severe malarial infection with cerebral involvement as well as hypoglycaemia, circulatory collapse and renal failure is often difficult to diagnose since the condition is only rarely seen in Scandinavia. This report describes a 49 year old seaman, who was admitted to hospital with a clinical picture of sepsis with multiorgan involvement including cerebral affection. Subsequently, it turned out that the patient had a severe infection with Plasmodium falciparum, involving more than 50 per cent of the red blood cells. Despite being comatose for one week with repeated attacks of grand mal type, and requiring 11 days mechanical ventilation plus dialysis for 4 weeks, he recovered uneventfully and was dismissed from hospital with only minor neurological sequelae. Even severe malaria with cerebral involvement can result in full restitution if the diagnosis is made early and exchange transfusion plus treatment with relevant drugs are instituted promptly.

Animals↗

[Renal calculi in an infant].

Urinary concretions, particularly in the upper urinary tract, occur in otherwise healthy children in connection with Bacillus Proteus urinary infections. In other European countries, this occurs in 40-70% while, on the other hand, it is particularly rare in Scandinavia. A case of obstructing pelvic concretion in a boy aged three months is presented. This is the youngest case which could be found in the literature. Pyelolithotomy was performed and the child has been free from recurrence for six years. At the commencement of the disease, pain due to renal calculi may be misinterpreted as being due to three-months intestinal colic. Formation of calculi is presumed to be due the ability of Bacillus Proteus to form urease. The frequency of recurrences is 3-8% and is lowest if the urine can be maintained sterile for the first three months after removal of the stone.

Humans↗

Scientific rationale for the 1989 recommended dietary allowance for selenium.

During the past 15 years, our knowledge of human selenium requirements has improved greatly, primarily because of research conducted in the People's Republic of China. Dietary surveys demonstrated that Keshan disease, a juvenile cardiomyopathy, was absent in parts of China where the food supply provided at least 19 and 13 micrograms selenium per day for men and women, respectively. Such intakes can be regarded as minimum daily requirements for selenium. Chinese scientists also carried out a study in an area where Keshan disease was prevalent to determine the amount of dietary selenium needed to maximize the activity of the selenium-containing enzyme, glutathione peroxidase, in plasma. For a man weighing 60 kg, enzymatic activity reached a plateau at selenium intakes of about 40 micrograms per day. These data were used by the US National Research Council as the basis for its 1989 Recommended Dietary Allowance (RDA) for selenium. The RDA was calculated as 70 and 55 micrograms per day for adult men and women, respectively, after correcting for differences in body size and taking into consideration possible individual variations in requirements. This RDA is readily satisfied by typical diets in countries with relatively selenium-rich soils, such as the United States. In selenium-poor areas of the world (eg, China, New Zealand, Scandinavia), diets would not readily furnish such intakes.

Animals↗

[Nephropathia epidemica. Hantavirus and acute renal insufficiency].

Puumala virus belongs to the hantavirus group and as other members of the group it can cause acute renal insufficiency. Other hantaviruses are responsible for Korean hemorrhagic fever and other hemorrhagic fevers with renal involvement. In Scandinavia, hantavirus nephropathy is better known as nephropathia epidemica. Hantavirus cause asymptomatic infections in mice and rats and the virus is thought to be transmitted to man via inhalation of desicated saliva, urine or feces from infected animals. In the other Nordic countries, the bank vole (Clethrionomys glareolus) is the commonest natural host. Laboratory infections from rats have been reported from all over the world. The disease presents with fever, back and/or abdominal pain, acute renal insufficiency and a bleeding tendency. The latter is usual less pronounced in the European than in the Asian forms of hantavirus infection. The disease is commoner in men and is endemic in forested areas. The greatest incidence is seen in those years when the numbers of mice are greatest. The mortality in nephropathia epidemica appears to be less than 0.5% in contrast to a mortality of about 10% in Korean hemorrhagic fever. Diagnosis is made by demonstration of a significant increase in antibody titer to hantavirus. Treatment is symptomatic and consists primarily of restitution of fluid and electrolyte balance, at times with dialysis. After recovery from hantavirus infection renal function returns to normal. The incidence and prevalence of nephropathia epidemica in Denmark are unknown. The first two cases of Puumala virus infection in Denmark are reported.

Acute Kidney Injury↗

Canadian cardiovascular disease mortality: first generation immigrants versus Canadian born.

Cardiovascular disease (CVD) is the major cause of death in Canada, as it is in most industrialized countries. Studies have shown that CVD mortality rates vary among ethnic groups. Since about one in six Canadian residents is a first generation immigrant, it is important to consider ethnic background when interpreting Canadian health statistics or planning health services. Overall, lower CVD mortality rates were found for first generation Canadians from Latin America, China and South Asia; higher rates are indicated for those from Scandinavia and Africa. The rates for North America are similar to those found for Eastern and Western Europe. Between two five-year time periods (1969-73 and 1984-88), CVD mortality rates generally were found to decrease, except for immigrants from Africa (age 35+). The rates were consistently higher for males than for females.

Adult↗

[Treatment of infections caused by group A beta-hemolytic streptococci].

Since 1987 the number of severe and fatal cases of group A-beta-hemolytic streptococci (GAS) infections has increased in Scandinavia. It therefore seems reasonable to stress the monitoring, diagnosis and treatment of infections caused by GAS. Treatment with phenoxymethylpenicillin for ten days is recommended for patients with uncomplicated disease. Patients with severe disease should be treated with benzylpenicillin intravenously. We discuss alternative antibiotics, treatment of immunological complications, and general hygienic precautions.

Adult↗