Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Names”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,315 records · Page 73Linked to original sources
PubMed1988

Impaired word naming in right-brain-damaged right-handers: error types and time-course analyses.

The purpose of this study is to search for cues that could account for the fact that right-hemisphere lesions affect word naming when the criterion for naming is semantic. The authors analyzed the errors as well as the time course of productions of 35 vascular right-brain-damaged subjects (RBD) and 20 control subjects (C) in a semantic-based word-naming task. Results show that there are no differences between groups in terms of (a) the number of errors produced and, (b) the patterns of error types. However, results also show a reduction of verbal fluency for semantic criteria in RBD-subjects present only after the first 30 seconds of production. These results indicate that reduction of word production in RBD-subjects is not the consequence of nonspecific factors such as perseveration or spontaneity, but reflects problems with the less automatized processes permitting exploration of semantic organization, either because scanning process are affected, or because the presence of a discreet semantic impairment prevents scanning from being as efficient. Given that efficient exploration of semantic knowledge is important for lexico-semantic functioning, the present results suggest that the right hemisphere contributes to some aspects of lexico-semantic processing necessary for language production.

Brain Damage, Chronic↗
PubMed1988

Internal representations and the conceptual operation of color in pure alexia with color naming defects.

This research examined the structure of internal representation and the conceptual operation of color in two pure alexic cases (Case I and Case II) with color naming defects. Experiment I investigated the structure of the internal representation of different kinds of colors using a similarity judgment task. Experiment II examined categorical judgments of perceived colors using a two-alternative-forced choice task. Experiment III tested the classification of perceived colors using a color sorting task. The performance of Case I essentially fell within the normal range while the results of Case II showed some impairment in the conceptual operation of color. Analysis of the responses obtained from these experiments indicated that the color naming defects in Case I can be explained in terms of visual-verbal disconnection. However, the naming defects in Case II reflect disfunction in some other higher cortical processes coupled with visual-verbal disconnection.

Color Perception↗
PubMed1990

Enhancement of naming in nonfluent aphasia through gesture.

In a number of studies that have examined the gestural disturbance in aphasia and the utility of gestural interventions in aphasia therapy, a variable degree of facilitation of verbalization during gestural activity has been reported. The present study examined the effect of different unilateral gestural movements on simultaneous oral-verbal expression, specifically naming to confrontation. It was hypothesized that activation of the phylogenetically older proximal motor system of the hemiplegic right arm in the execution of a communicative but nonrepresentational pointing gesture would have a facilitatory effect on naming ability. Twenty-four aphasic patients, representing five aphasic subtypes, including Broca's, Transcortical Motor, Anomic, Global, and Wernicke's aphasics were assessed under three gesture/naming conditions. The findings indicated that gestures produced through activation of the proximal (shoulder) musculature of the right paralytic limb differentially facilitated naming performance in the nonfluent subgroup, but not in the Wernicke's aphasics. These findings may be explained on the view that functional activation of the archaic proximal motor system of the hemiplegic limb, in the execution of a communicative gesture, permits access to preliminary stages in the formative process of the anterior action microgeny, which ultimately emerges in vocal articulation.

Aged↗
PubMed1990

Naming and categorical knowledge in Alzheimer's disease: the process of semantic memory deterioration.

Semantic memory deterioration in Alzheimer's disease (AD) has been theorized to proceed from a loss of object attribute knowledge to a loss of category knowledge. The theory is based on the belief that naming is a computational process requiring object attribute knowledge. It is strengthened by reports that AD patients misname by giving category information and perform poorer on tests of attribute than category knowledge. The purpose of this study was to test the theory's validity by administering naming and category knowledge tasks to AD and normal elderly control subjects. Results revealed a theoretically unexpected outcome, that is, naming became easier relative to the recall and recognition of category information.

Aged↗
PubMed1990

Preserved recognition of familiar personal names in global aphasia.

Recognition of proper and common nouns was compared in four patients diagnosed with global aphasia secondary to ischemic left-hemisphere infarction. For proper noun recognition, subjects matched the spoken or written name of a famous person to a photograph, and for common nouns, subjects were tested on standardized and special word recognition tests. As expected, common noun recognition was severely compromised in the aphasic patients. In contrast, familiar personal names, despite their greater length and complexity, were recognized equally well by aphasic and normal control subjects. The right hemisphere may mediate the ability to recognize personally familiar names, as it may be specialized for establishing personally relevant environmental stimuli.

Aged↗
PubMedDate not supplied

Recall of object names and colors of objects in normal aging and Alzheimer's disease.

The Subject Performed Task (SPT) was used in order to determine whether normal older adults and patients with Alzheimer's disease (AD) differ in the ability to remember verbal and physical information. Mildly and moderately demented patients and normal controls were instructed to perform a series of SPTs involving objects, and were examined on recall of the object names and the colors of the objects. It was assumed that encoding and retrieval of the object names require a more extensive semantic elaboration than encoding and retrieval of the colors of the objects. Results showed that normal older adults performed at a higher level than the groups of mildly and moderately demented patients, and that the colors of the objects were better remembered than the object names for all groups. However, the magnitude of impairment in the AD groups was equal for both types of information. These results are in agreement with the notion that the episodic memory impairment in AD is global, rather than mediated by deficits in semantic memory.

Journal Article↗
PubMed1996

The nitric oxide synthase inhibitor L-NAME reduces inhibitory components of somato-vesical parasympathetic reflexes in the rat.

Reflex discharges of pelvic postganglionic parasympathetic efferent fibers on the bladder surface induced by afferent volleys in the hindlimb nerve have been recorded in anesthetized rats, and the effects of the nitric oxide synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME) on the reflex discharges have been investigated. Single electrical stimulation of the tibial nerve at intensities supramaximal for excitation of A- and C-afferents evoked a reflex discharge in the postganglionic parasympathetic efferents with four distinct components, i.e., two inhibitory components with latencies of 49 and 203 ms, respectively, and two excitatory components with latencies of 126 and 308 ms, respectively. These reflexes could be observed when the bladder was expanded, but not markedly when the bladder was empty. Intravenous administration of L-NAME resulted in (a) a reduction in the level of resting discharge, (b) a reduction in the size of the first inhibitory component, (c) the disappearance of the second inhibitory component and (d) the exaggeration of the late excitatory component. Intracisternal injection of L-NAME caused changes similar to those observed following intravenous injection. The results suggest that inhibitory components of the somato-pelvic parasympathetic reflex are mediated by pathways that utilize nitric oxide as a neurotransmitter or neuromodulator at the level of the brainstem.

Animals↗
PubMed1983

Name and face matching in one or two visual fields: a test of models of hemispheric specialization.

In two experiments a name and a face (each male or female) were simultaneously flashed to either the same or opposite visual fields (left or right), for matching congruent (same sex) or incongruent (opposite sex), to test the predictions of various models of hemispheric specialization. While overall best performance occurred with a face in the left visual field (LVF) and a name in the right visual field (RVF), and worst with the opposite configuration, the general pattern of results was incompatible with either a direct access model or an activational/attentional account. The results were, however, most compatible with the predictions of a semispecialized hemispheres account, whereby cerebral asymmetries are seen as relative rather than absolute, either hemisphere being capable of processing either kind of material (verbal or visuospatial), but to different levels of efficiency. However, despite the fact that the stimulus materials had previously been shown to produce stable and consistent lateral asymmetries in the predicted directions when presented in isolation, in the composite, integrative matching task the position of the name seemed to be the major determinant of the resultant asymmetries. It would seem therefore that when such stimuli are to be cross matched, either left hemisphere (language) processes somehow dominate right hemisphere (visuospatial) processing (though not in the way that would be predicted by a simple activational/attentional account) or the left hemisphere's greater capacity predominates.

Discrimination Learning↗
PubMed1995

L-NAME, an inhibitor of nitric oxide synthase, blocks the established allodynia induced by intrathecal administration of prostaglandin E2.

We recently reported that intrathecal (i.t.) administration of prostaglandin E2 (PGE2) to conscious mice induced allodynia, a state of discomfort and pain evoked by innocuous tactile stimuli. In the present study, we examined the effect of the PGE receptor EP1 subtype antagonist ONO-NT-012, the N-methyl-D-aspartate (NMDA) receptor antagonist MK-801, and the NO synthase inhibitor N omega-nitro-L-arginine methyl ester (L-NAME) on the allodynia. The PGE2-induced allodynia was blocked by simultaneous i.t. injection of ONO-NT-012, MK-801, or L-NAME. However, 5 min after i.t. injection of PGE2, the allodynia was significantly blocked by i.t. L-NAME, but not by i.t. ONO-NT-012 or MK-801. These results demonstrate that the PGE2-induced allodynia, once developed, does not require the continued agonist occupancy of EP1 and NMDA glutamate receptor sites.

Animals↗
PubMed1995

Chronic administration of L-NAME in drinking water alters working memory in rats.

To examine the role of nitric oxide (NO) in the maintenance of working memory of rats, the effects of chronic administration (in drinking water) of the NO synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME), on this behavior was examined with a simple test of remembering recently explored objects. Unlike other working memory tasks that require a subject to perform for a reward such as food or water or to avoid shock, our task measured spontaneous exploration of novel and familiar objects and has been described as a "pure" working memory task [9]. Normal subjects spend significantly more time in contact with new environmental components and less time with familiar objects. A subject that extensively reexplores a stimulus with which it has previous experience is presumed to exhibit some memory loss associated with the object. Memory changes were evaluated by measuring the relative time subjects explored familiar versus new stimulus objects. Rats (n = 15) that chronically drank L-NAME (approximately 90 mg/kg/day) for 14 days spent significantly less time exploring a novel object than did rats (n = 13) that drank only tap water (p < .05). This effect of L-NAME was abolished by concurrent administration of L-Arginine (approximately 4.5 g/kg/day). Total object exploration was not affected by our drug treatments, suggesting that our object discrimination task is not activity dependent. These data are consistent with the hypothesis that NO is required for some forms of working memory.

Analysis of Variance↗
PubMed1987

Microbial nomenclature: a list of names and origins.

Microbial nomenclature underwent a large number of changes in the 1970s. Many species of pathogens were added and many others experienced name changes. These modifications primarily were due to two unrelated factors: the use of new DNA hybridization techniques and the advent of computerized literature searches to establish historical precedence. In 1980 an approved list of microbial names was published. This list fixed and legitimized bacterial nomenclature. All future additions or alterations to it had to pass international scientific committees. This list has now been accepted by the scientific community. The derivation of these names are presented in this review.

Bacteria↗
PubMed2004

Gender congruency effects in picture naming.

The analysis of speech error corpora in various gender-marked languages has shown that noun substitutions tend to preserve grammatical gender. This result has been taken as an indication that grammatical gender could play a constraining role during the process of lexical selection. To gain insights on the status of grammatical gender in the speech production system, we discuss this hypothesis and we report three picture naming experiments. We attempted to observe gender-marked context effects in the course of error-free speech production. Participants named pictures shortly after processing a prime that was or was not gender marked and that was or was not congruent with the name of the picture. A clear congruency effect was observed, involving both facilitation in the gender congruent conditions and inhibition in gender incongruent conditions. Different interpretations of this effect and of previously reported gender context effects are discussed in the context of current models of speech production.

Female↗
PubMed2005

Automatic identification of confusable drug names.

OBJECTIVE: Many hundreds of drugs have names that either look or sound so much alike that doctors, nurses and pharmacists can get them confused, dispensing the wrong one in errors that can injure or even kill patients. METHODS AND MATERIAL: We propose to address the problem through the application of two new methods-one based on orthographic similarity ("look-alike"), and the other based on phonetic similarity ("sound-alike"). In order to compare the effectiveness of the new methods for identifying confusable drug names with other known similarity measures, we developed a novel evaluation methodology. RESULTS: We show that the new orthographic measure (BI-SIM) outperforms other commonly used measures of similarity on a set containing both look-alike and sound-alike pairs, and that a new feature-based phonetic approach (ALINE) outperforms orthographic approaches on a test set containing solely sound-alike pairs. However, an approach that combines several different measures achieves the best results on two test sets. CONCLUSION: Our system is currently used as the basis of a system developed for the U.S. Food and Drug Administration for detection of confusable drug names.

Algorithms↗
PubMed2004

Predictive influence of phonological processing, morphological/syntactic skill, and naming speed on spelling performance.

This paper focuses on the predictive influence of phonological awareness, morphological/syntactic skill, and naming speed on spelling. The retrospective study correlated spelling performance in a group of 199 French-speaking children at the end of grade 2 with earlier capacities for phonemic manipulation, morphological/syntactic correction, and naming speed, assessed at the end of grade 1. The results are consistent with an integrative model that challenges the unitary phonological disorder hypothesis and confirmed that in French, as in other languages, naming speed is an independent predictor of reading performance.

Age Factors↗
PubMed2005

Color makes a difference: two-dimensional object naming in literate and illiterate subjects.

Previous work has shown that illiterate subjects are better at naming two-dimensional representations of real objects when presented as colored photos as compared to black and white drawings. This raises the question if color or textural details selectively improve object recognition and naming in illiterate compared to literate subjects. In this study, we investigated whether the surface texture and/or color of objects is used to access stored object knowledge in illiterate subjects. A group of illiterate subjects and a matched literate control group were compared on an immediate object naming task with four conditions: color and black and white (i.e., grey-scaled) photos, as well as color and black and white (i.e., grey-scaled) drawings of common everyday objects. The results show that illiterate subjects perform significantly better when the stimuli are colored and this effect is independent of the photographic detail. In addition, there were significant differences between the literacy groups in the black and white condition for both drawings and photos. These results suggest that color object information contributes to object recognition. This effect was particularly prominent in the illiterate group.

Adult↗
PubMedDate not supplied

Naming pseudowords in Spanish: effects of syllable frequency.

Three naming experiments were conducted to examine the role of the first and the second syllable during speech production in Spanish. Facilitative effects of syllable frequency with disyllabic words have been reported in Dutch and Spanish (Levelt & Wheeldon, 1994; Perea & Carreiras, 1998). In both cases, the syllable frequency effect was independent of-and additive to-the effect of word frequency. However, Levelt and Wheeldon (1994) found that words ending in a high-frequency syllable were named faster than words ending in a low-frequency syllable, whereas Perea and Carreiras (1998) found a facilitative effect of syllable frequency for the initial syllable. In Experiments 1-2, we manipulated the frequency of the first and the second syllable of disyllabic CV.CV pseudowords. In Experiment 3, participants named CVC disyllabic pseudowords for which only the frequency of the first syllable was manipulated. The experiments showed a facilitative effect of frequency of the first syllable. The findings are discussed in terms of the current models of speech production.

Humans↗
PubMed2005

Semantic feature knowledge and picture naming in dementia of Alzheimer's type: a new approach.

This study addresses continuing controversies concerning the nature of semantic impairment in early dementia of the Alzheimer type (DAT), and the relationship between conceptual knowledge and picture naming. A series of analyses of fine-grained feature knowledge data show that: (1) distinctive features of concepts were more vulnerable than shared; (2) the amount of attribute knowledge about a concept was associated reliably, and in a graded fashion, with the ability to name a picture of that item; (3) sensory features were differentially important in naming; and (4) the degree of disruption to different types of attribute knowledge did not vary between items from living and nonliving domains. These findings are discussed in the context of contemporary cognitive and computational models of semantic memory organisation.

Aged↗
PubMed2005

Drawing: its contribution to naming in aphasia.

Drawing in aphasia therapy has been used predominately as a substitution for speech or to augment communication when other modalities are non-functional. The value of drawing as a route for facilitating verbal expression has not been a focus of prior research. We compared the usefulness of drawing and writing as compensatory strategies for improving naming in individuals with aphasia. Activation patterns of writing and drawing in healthy adults were examined using fMRI. Clinical results suggest that drawing facilitated naming whereas writing diminished accurate naming responses, and that drawing quality is not relevant to this facilitatory effect. Functional MRI findings revealed strong bi-hemispheric activation of semantic and phonological networks while drawing that may support our clinical findings.

Aged↗