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At least 1,297 records · Page 72Linked to original sources

Understanding acceleration-induced displacement artifacts in phase-contrast MR velocity measurements.

A theoretical framework for understanding acceleration-induced errors in phase-contrast magnetic resonance velocity measurements has been developed. An important result of this framework is the interpretation of acceleration-induced velocity errors as displacement artifacts due to the delay between velocity and spatial encoding. A rotating-disk phantom was used to confirm the theoretically predicted displacement times (the difference between theory and experiment was 8.2%). Errors were also observed in velocity profiles measured in regions of fluid acceleration downstream from a step stenosis. The magnitude of these errors could be predicted and corrected by using the analytic framework.

Artifacts↗

Artifacts in functional magnetic resonance imaging from gaseous oxygen.

Unexpectedly large fluctuations in signal intensity were identified in the functional MRI (FMRI) of normal subjects breathing pure oxygen intermittently. To test the hypothesis that the signal changes were due to fluctuating concentrations of gaseous (paramagnetic) oxygen in the magnetic field, echo planar gradient echo images were acquired of a phantom contiguous to an oxygen mask through which pure oxygen was administered intermittently via plastic tubing. As a control, room air was administered intermittently or oxygen continuously in the same experimental protocol. Signal intensity changes of up to 60% temporally correlated with the administration of oxygen were produced in the phantom. In functional images prepared from the echo planar images, the signal intensity changes resulted in artifacts especially at interfaces in the phantom. The intermittent administration of pure oxygen during acquisition of data for FMRI may produce signal intensity changes that stimulate or obscure function.

Artifacts↗

Detection and elimination of motion artifacts by regeneration of k-space.

A method has been developed using techniques from partially parallel imaging (PPI) to detect localized inconsistencies in k-space that are caused by certain types of motion. The inconsistent data are discarded and consistent data regenerated from the remaining data using PPI techniques. The price is a small decrease in signal-to-noise ratio (SNR) and additional postprocessing. An iterative scheme is presented which does not require separately acquired coil sensitivity information for the PPI reconstructions. This method has been found to reduce artifact levels in phantom and in vivo test studies.

Artifacts↗

Phase coherent averaging in magnetic resonance spectroscopy using interleaved navigator scans: compensation of motion artifacts and magnetic field instabilities.

The quality of spectra in (1)H magnetic resonance spectroscopy (MRS) is strongly affected by temporal signal instabilities during the acquisition. One reason for these instabilities are hardware imperfections, e.g., drifts of the main magnetic field in superconducting magnets. This is of special concern in high-field systems where the specification of the field stability is close to the spectral linewidth. A second major potential source of artifacts, particularly in clinical MRS, is patient motion. Using standard acquisition schemes of phase-cycled averaging of the individual acquisitions, long-term effects (field drifts) as well as changes on a shorter time scale (motion) can severely reduce spectral quality. The new technique for volume-selective MRS presented here is based on the additional interleaved acquisition of a navigator signal during the recovery time of the metabolite acquisition. It corrects for temporal signal instabilities by means of a deconvolution of the metabolite and the navigator signal. This leads to phase-corrected individual metabolite scans and upon summation to a phase-coherent averaging scheme. The interleaved navigator acquisition does not require any user interaction or supervision, while sequence efficiency is maintained.

Animals↗

Sensitivity-encoded single-shot spiral imaging for reduced susceptibility artifacts in BOLD fMRI.

Sensitivity encoding (SENSE) with iterative image reconstruction was used to shorten the readout duration in single-shot spiral imaging by a factor of 2. This enabled susceptibility-related blurring and signal loss artifacts to be reduced and spatial resolution to be improved. As a beneficial side effect, the gradient duty cycle was also reduced. The spiral SENSE technique was applied to functional MRI (fMRI) with blood oxygen level-dependent (BOLD) contrast and compared to a conventional spiral acquisition. Stimulation experiments were performed in seven volunteers using motor, visual, and taste paradigms. The signal-to-noise ratio (SNR) and signal-to-fluctuation-noise ratio (SFNR) of the SENSE acquisitions were reduced by 20% and 13%, respectively, with respect to the longer readout. The overall activation detected was comparable to that of the conventional spiral acquisition, even though difficulties in reproducing the stimulation response hampered the evaluation. In some cases, the application of SENSE enabled recovery of activation in regions affected by signal loss due to field inhomogeneity.

Artifacts↗

Reference-scan-free method for automated correction of Nyquist ghost artifacts in echoplanar brain images.

One of the most common artifacts for echo-planar imaging is the Nyquist ghost, typically overcome with the aid of a reference scan preceding the actual image acquisition. In this work, a nonlinear phase correction obviating the need for a reference scan is proposed. The method is based on computing the second moments of the even and odd subdomains of the phase-encoding k-space data to retrieve the phase disparities between even and odd echoes. The method's underlying assumption is that the images are dominated by their low frequency and symmetric part. In vivo data demonstrate the effectiveness of the algorithm showing ghost suppression comparable to that achievable with the reference-scan method.

Algorithms↗

Ghost artifact cancellation using phased array processing.

In this article, a method for phased array combining is formulated which may be used to cancel ghosts caused by a variety of distortion mechanisms, including space variant distortions such as local flow or off-resonance. This method is based on a constrained optimization, which optimizes SNR subject to the constraint of nulling ghost artifacts at known locations. The resultant technique is similar to the method known as sensitivity encoding (SENSE) used for accelerated imaging; however, in this formulation it is applied to full field-of-view (FOV) images. The method is applied to multishot EPI with noninterleaved phase encode acquisition. A number of benefits, as compared to the conventional interleaved approach, are reduced distortion due to off-resonance, in-plane flow, and EPI delay misalignment, as well as eliminating the need for echo-shifting. Experimental results demonstrate the cancellation for both phantom as well as cardiac imaging examples.

Artifacts↗

Spiral-in/out BOLD fMRI for increased SNR and reduced susceptibility artifacts.

BOLD fMRI is hampered by dropout of signal in the orbitofrontal and parietal brain regions due to magnetic field gradients near air-tissue interfaces. This work reports the use of spiral-in trajectories that begin at the edge of k-space and end at the origin, and spiral in/out trajectories in which a spiral-in readout is followed by a conventional spiral-out trajectory. The spiral-in trajectory reduces the dropout and increases the BOLD contrast. The spiral-in and spiral-out images can be combined in several ways to simultaneously achieve increased signal-to-noise ratio (SNR) and reduced dropout artifacts. Activation experiments employing an olfaction task demonstrate significantly increased activation volumes due to reduced dropout, and overall increased SNR in all regions.

Amygdala↗

Correction for chemical-shift artifacts in 19F imaging of PFOB: simultaneous multislice imaging.

One of the difficulties encountered in 19F NMR imaging of fluorinated blood substitutes is that these compounds often exhibit complex multipeak spectra. These peaks result in chemical-shift artifacts along the readout direction and blurred images. In addition, each peak excites a different slice (mis-selection) when a slice selection gradient is applied during the selective rf pulse. A simultaneous multislice imaging method has been developed to solve the inherent problem of mis-selection. The essence of this method is to use the two strongest peaks of the spectrum to excite controlled different multiple slices simultaneously, with or without a slice gap. The images corresponding to the two spectral lines are then separated from in- and out-of-phase images (Dixon method). This method corrects the problem of mis-selection and either improves the SNR or increases the number of slices over spectrally selective methods which image only one peak.

Artifacts↗

Sensitivity enhancement and reduction of Gibbs artifact in T2-weighted imaging using variable tip angle excitation.

Introduction of a Gaussian weighting function into the phase encoding of the spin-echo imaging method via variable tip angle excitation, with concomitant optimization of the recycle delay, is shown to increase the sensitivity of T2-weighted imaging by up to 40%. In addition, the Gibbs artifact associated with sharp boundaries is reduced considerably without the need for postprocessing of the data.

Artifacts↗

Reduction of susceptibility artifact in gradient-echo imaging.

A new technique with which susceptibility artifact in gradient-echo imaging can be reduced substantially by use of a tailored RF pulse is described. The proposed technique can ideally be applied to the case where high local magnetic field inhomogeneity is dominated by the susceptibility. The signal loss and void phenomena due to susceptibility in a voxel are studied and a correction method is also proposed. The description of the tailored RF pulse and its proposed application are given and experimental results obtained using a human volunteer with a 2.0-T KAIS NMR system are presented.

Artifacts↗

Correction of chemical-shift artifacts in 19F imaging of PFOB: a robust signed magnitude method.

This paper describes a method for correcting the chemical-shift artifacts in 19F NMR imaging of perfluoroctylbromide emulsion (PFOB) by utilizing the two spectral peaks of PFOB which have a long T2 value in conjunction with the Dixon method. Corrected images are obtained from the magnitude of the measured images using the sign determined from the phase images. The method was tested in the presence of several phase deformation factors, such as static magnetic field inhomogeneity and inaccurate time shift of the pi refocusing pulse, which affect the phase errors of each pixel in the reconstructed image. The advantage of the signed magnitude method is demonstrated experimentally by comparing it with the currently used complex and magnitude summation/subtraction methods.

Artifacts↗

Correction of chemical-shift artifacts in multislice F-19 imaging with perfluorooctyl bromide.

Chemical-shift artifact correction methods for multislice F-19 imaging with perfluorooctyl bromide are described and results obtained with physical phantoms presented. Utilization of the two long-T2 spectral peaks of PFOB in multislice imaging enhances the imaging efficiency considerably. Simultaneous imaging of the adjacent slices is achieved by appropriately adjusting the slice selection gradient amplitude, the bandwidth, and the slice position offset frequency of the selective RF pulses in relation to the frequency separation between the two peaks.

Algorithms↗

Correction of translational motion artifacts in multi-slice spin-echo imaging using self-calibration.

In this paper, we describe a method for detecting and correcting in-plane bulk translational motion in multislice spin-echo imaging using self-calibration and postprocessing. A constant phase encoding offset between slices is used to evenly spread out the low spatial frequency echoes to allow accurate motion detection by self-calibration. Motion detection in both x and y directions is achieved by interchanging the readout and phase encoding directions for the alternate slices. Displacements are determined by cross correlating the modulus of each 1D transformed echo with a reference box car function whose width equals that of the imaged object. In addition, phase errors induced by the velocity in the readout direction are estimated and corrected using the displacement data. The results obtained from knee studies at 0.5 T and 1.5 T show that the artifacts due to translational motions are significantly suppressed upon correction. The method does not require any additional pulses or time, and the data processing can be easily implemented.

Algorithms↗

A potentially artifact-free oral contrast agent for gastrointestinal MRI.

The combination of diamagnetic barium sulfate and superparamagnetic iron oxide (SPIO) in one suspension produces a macroscopic cancellation of positive and negative magnetic susceptibility components that can potentially eliminate susceptibility artifacts even with gradient echo pulse sequences. The relaxation properties that make the SPIO suspension a useful negative contrast agent are retained.

Administration, Oral↗

Adaptive Fourier threshold filtering: a method to reduce noise and incoherent artifacts in high resolution cardiac images.

We introduce an image processing method which reduces white noise and random artifacts in sets of high resolution, time resolved images. At each pixel, the processing consists of: 1) the isolation of a time intensity curve (TIC), 2) Fourier transformation of each TIC, 3) application of a threshold to remove low intensity coefficients, 4) inverse transformation to generate noise reduced TICs which are recombined to form images with improved signal-to-noise ratio (SNR). Noise filtering by Fourier thresholding is demonstrated on a set of cardiac images, resulting in a reduction of the noise energy by approximately 90%.

Artifacts↗

Susceptibility artifact reduction in fat suppression.

Strong fat signal in regions where a large susceptibility difference exists, for instance at the interface between air and tissue near the maxillary sinus, may not be eliminated by currently available fat suppression techniques without sacrificing the overall quality of the images. In this article, we show that this fat signal, which appears as a susceptibility artifact, can be significantly reduced by using an optimized presaturation pulse with sharp edges and a broad bandwidth, while causing minimal disturbance of the water signal. Several optimized presaturation pulses can be reproduced by the Fourier coefficients provided in the Appendix.

Adipose Tissue↗

The diminishing variance algorithm for real-time reduction of motion artifacts in MRI.

A technique has been developed whereby motion can be detected in real time during the acquisition of data. This enables the implementation of several algorithms to reduce or eliminate motion effects from an image as it is being acquired. One such algorithm previously described is the acceptance/rejection method. This paper deals with another real-time algorithm called the diminishing variance algorithm (DVA). With this method, a complete set of preliminary data is acquired along with information about the relative motion position of each frame of data. After all the preliminary data are acquired, the position information is used to determine which data frames are most corrupted by motion. Frames of data are then reacquired, starting with the most corrupted one. The position information is continually updated in an iterative process; therefore, each subsequent reacquisition is always done on the worst frame of data. The algorithm has been implemented on several different types of sequences. Preliminary in vivo studies indicate that motion artifacts are dramatically reduced.

Algorithms↗