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At least 1,297 records · Page 72Linked to original sources
PubMed1976

Urinary infections: which antibacterial drug and regimen?

Urinary tract infection (UTI) is a common problem in clinical practice. The proper criteria for the diagnosis and treatment of individual and recurrent episodes of UTI are described. The success of antibacterial therapy is dependent upon the urinary concentration of the drug and not its plasma or lymphatic concentration.

Anti-Bacterial Agents↗
PubMed1987

Single-dose versus five-day treatment with trimethoprim for the acute dysuria/pyuria syndrome in women.

The efficacy of a single dose trimethoprim in the treatment of the dysuria/pyuria syndrome in women was prospectively studied in an open, controlled and randomized trail. Of 90 women aged 18-60 years 68 had and 22 had not significant bacteriuria when the urine was cultured. The 42 women in the single-dose group received trimethoprim 400 mg once while the 48 in the multi-dose group received trimethoprim 200 mg X 2 for five days. One week after ended treatment 83% were cured in the single-dose group, and 85% in the multi-dose group. One relapse and six reinfections occurred in the single-dose group, no relapse and seven reinfections in the multi-dose group. Two patients in the single-dose group and eight in the multi-dose group reported adverse effects. A single dose of trimethoprim seems to be safe and effective in the treatment of acute dysuria/pyuria syndrome in women.

Acute Disease↗
PubMed1979

The effect of short-term high-dose treatment with methenamine hippurate of urinary infection in geriatric patients with indwelling catheters. II. Evaluation by means of a quantified urine sediment.

The urine sediment of 12 geriatric patients with indwelling catheters was quantified by the glutaraldehyde-cytocentrifuge method prior to, during and after a clinical trial of methenamine hippurate (MH), 2 g x 3 daily given for 34 days as the sole therapeutic agent for the urinary tract infection. The median leukocyte concentration in the urine of these patients was 100 cells/microliter (Q1 - Q3 50-350), i.e. tenfold higher than the upper normal limits reported in healthy probands. The median bacteriuria in the control period was 12 x 10(5) bacteria/ml urine, interquartile range 10-60 x 10(5) bacteria/ml and extreme individual values 300-500 x 10(5) bacteria/ml. Hematuria, defined as greater than or equal to 24 erythrocytes/microliter urine, was not prominent and could not be correlated with MH treatment, nor with catheter changes. The reported observations suggest that short-term high-dose treatment with MH as sole therapeutic agent reduced pyruria and bacteriuria in the group of patients studied.

Aged↗
PubMed1978

Reversible renal side effects of intra-articular osmic acid injection.

In 101 patients treated for knee joint hydrops with intra-articular osmic acid injection, an increased incidence of proteinuria and microscopic haematuria was noted on the first day after injection. This increase subsided rapidly and had disappeared 3 days after the injection. Three patients showed transient glycosuria. No signs of permanent renal damage appeared in any patient.

Glycosuria, Renal↗
PubMed1981

Significance of C-reactive protein elevation in the pretreatment stage of systemic lupus erythematosus.

The significance of C-reactive protein (CRP) elevation in patients with systemic lupus erythematosus (SLE) in the pretreatment stage was assessed with reference to other laboratory data obtained simultaneously. Sixteen of 31 cases were CRP-positive, and the CR-positive group contained significantly more cases with urinary cellular casts and with a high anti-DNA antibody titer, compared with the CRP-negative group. We suggest that CRP in patients with SLE, as measured at the time of the first consultation, reflects the severity of the disease. This includes those cases complicated by nephropathy.

Adolescent↗
PubMed1996

Urinalysis. When--and when not--to order.

Although routine urinalysis is common, the results are important in management of only certain diseases. Screening urinalysis to detect asymptomatic bacteriuria is recommended in adults 60 years of age or older, diabetic patients of any age, pregnant women, and adolescents. A positive result for protein on dipstick urinalysis should be evaluated in conjunction with other clinical and laboratory data (eg, the patient's age, physical findings, renal function, results of microscopic urinalysis). Evaluation of hematuria should always include dipstick analysis and microscopic examination of urine. Diabetes screening is best done with measurement of plasma glucose levels. Other available urinalysis tests include measurement of pH, specific gravity, ketones, bilirubin, and urobilinogen. In patients with renal or urinary tract disease, microscopic examination of urinary sediment is important.

Bacteriuria↗