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PubMed2006

Pectoralis major ruptures.

Although previously considered rare, ruptures of the pectoralis major muscle and tendon have become more common over the past 20 years with increasing participation in competitive sports and weight lifting. These injuries result from maximal eccentric contraction of the muscle with the arm held in an abducted, extended position. Most often, they occur near the tendon insertion. Complete ruptures are more common than partial tears, though many mild strains and partial tears likely go unreported or undiagnosed. Magnetic resonance imaging is the diagnostic study of choice when the diagnosis or extent of the injury is unclear. Partial tears and neglected complete tears with near complete restoration muscle strength after rehabilitation may be treated nonoperatively, with good results. Excellent results can be obtained with early anatomic repair for complete ruptures, though good results have also been reported with delayed repair of complete injuries. Early diagnosis and, when appropriate, anatomic surgical repair are the factors critical to optimizing patient outcomes after pectoralis major rupture.

Athletic Injuries↗
PubMed1996

[Surgical treatment of sternoclavicular osteomyelitis].

Osteomyelitis of the sternocosto-clavicular (SCC) articulation is a rare infection usually caused by Staphylococcus aureus and enterobacteria. It usually occurs in individuals with osteoarticular disease or predisposing factors. Prolonged antibiotic treatment and articular puncture are generally accepted. Authors do not agree on an established protocol. We report three cases of SCC septic arthritis in two previously healthy patients with two foci of infection (one perianal abscess and one dental extraction) and in one adult patient with Still's disease. Pain and intense inflammation was referred to the shoulder, with scarce leukocytosis and fever reaching 38 degrees C. The germs responsible were S. aureus, Bacteroides fragilis and B. oralis. Two of the patients had local, regional abscesses. Long-term antibiotic treatment failed in all cases and surgery for SCC resection and myoplasty of the pectoralis major muscle was required. Recovery was good and shoulder and arm mobility was excellent. We propose medical treatment and articular diagnostic-therapeutic puncture as the first line of therapy for this disease. When evolution is poor or when complications appear, such as abscesses or mediastinitis, we conclude that radical debridement and myoplasty of the pectoralis major muscle are indicated.

Adult↗
PubMed1979

Axillary vein entrapment.

This paper describes a patient with right axillary vein obstruction resulting from compression of the vein due to anomalous muscle tissue extending from the latissimus dorsi muscle across the neurovascular bundle to the pectoralis major muscle. This 'axillopectoral muscle' causing entrapment of the axillary vein has been described in only a few cases. These previous reports are discussed, with special reference to the symptoms and phlebographic findings. The obstruction and the symptoms caused by it are intermittent; the phlebographic features are characteristic.

Adult↗
PubMed1989

Muscle protein turnover and tenderness in broiler chickens fed cimaterol.

To investigate the impact of cimaterol (CIM) on muscle protein turnover, carcass and muscle composition, muscle cathepsin B + L activity and meat tenderness, 21-d-old broiler chickens (n = 88) were assigned to dietary treatments of either 0 or 1 ppm CIM. Fractional synthesis rates (FSR), fractional accretion rates (FAR), proximate composition and collagen content were determined in the breast muscle (BM); pectoralis major) and a group of leg muscles (LM; gastrocnemius and peroneous longus) from groups of six birds per treatment within each of two time periods (age = 38 or 56 d). Whole body composition, serum hydroxyproline content and BM cathepsin B + L activity also were measured. Fractional degradation rates (FDR) were calculated as the difference between FSR and FAR. Feeding CIM increased (P less than .01) whole body protein content. Weights of LM and percentage of body weight as BM and LM were increased (P less than .05) when CIM was included in the diet. Although FSR was not significantly reduced by CIM feeding it decreased (P less than .05) with increasing age. Due to decreases in FAR, FDR thereby was reduced by CIM 31.5% and 11.9% in BM and 38.2% and 37.4% in LM at 38 d and 56 d of age, respectively. Cathepsin B + L activities also were reduced 33.6% (P less than .01) and shear forces were increased by 41% (P less than .05) by CIM feeding. For chickens fed CIM, the correlation between cathepsin B + L activity and shear force was -.63 (P less than .01). Feeding CIM improved carcass leanness and muscling due to reductions in FDR and proteolytic enzyme activity. Feeding CIM also reduced meat tenderness.

Administration, Oral↗
PubMed1994

[Surgery of bilateral pulmonary aspergilloma].

A 60-year-old man with cough and fever was admitted to our hospital. Chest radiography revealed multiple bullae and fungus balls in both lungs. He was treated with MCZ and FCZ for about 2 months, but the chest radiograph shadows did not improve and the fever continued. A two-stage operation was performed. The bullae were incised and the fungus balls were removed, then a muscle flap plombage was made with a pectoralis major muscle, a latissimus dorsi muscle and an intercostal muscle. The postoperative course was uneventful and respiratory function was preserved.

Aspergillosis↗
PubMed1997

Characterization of satellite cells derived from chickens with the low score normal (LSN) muscle weakness.

Myogenic satellite cell clones were established from the pectoralis major muscle of chickens with the low score normal (LSN) muscle weakness and controls. The percentage of cells which attached to substrata and began to proliferate was higher for the control line than the LSN line (55% vs 30%). Furthermore, of those clones which initiated growth, 63% of the control cells and only 32% of the LSN cells proliferated to confluence in 25 cm2 tissue culture flasks. Proliferation rates were significantly lower with LSN satellite cells than with controls (p < 0.05). LSN satellite cells were less responsive to the mitogenic effects of chicken serum (p < 0.05) and differentiation rates were lower compared with controls (p < 0.05). There was a greater (p < 0.05) number of insulin-like growth factor receptors on LSN satellite cells compared with controls. The IGF receptor binding affinities (Kds) between the two cell lines were similar (p > 0.05). The results suggest that a defect in satellite cell physiology may contribute to the skeletal muscle weakness seen in the LSN line.

Animals↗
PubMed2005

Fertility and content of cadmium in pheasant (Phasianus colchicus) following cadmium intake in drinking water.

In this study, the effects of cadmium applied per os on fertility, live weight of newly hatched chicks, and cadmium concentrations in some organs of young and adult pheasants were investigated. The metal was applied at the concentration of 1.5 mg Cd(2+)/L during 3 months. After the egg laying, the numbers of eggs laid, cracked, and unfertilized were determined and the live weights of newly hatched chicks were measured. The cadmium concentrations in liver, kidney, and muscle (m. pectoralis) of young and adult pheasants were analyzed. We found that cadmium exposure of the adults did not affect the number of eggs laid but resulted in more eggs being damaged. Hatchlings were significantly heavier in the cadmium-treated group (21.36 +/- 2.28 g) compared to the control group (20.91 +/- 1.97 g) 4 weeks after the cadmium intake. Higher cadmium concentrations were observed in the muscle and kidney tissue of newly hatched pheasants after 4 weeks compared to the cadmium-exposed groups after 8 and 12 weeks. The cadmium concentrations in kidneys and liver increased significantly in adult pheasants. The metal had accumulated especially in kidneys of the adult pheasants and reached levels up to 9.64 mg/kg wet weight 3 months after the daily cadmium intake in drinking water. The concentration in liver of the adults was 3.53 mg/kg wet weight.

Animals↗
PubMed1998

[Subpectoral venous approach in implantable cardioverter defibrillator systems (ICD)].

Lead complications may have fatal consequences for ICD patients. Lead fractures have been reported to occur a long time after subclavian puncture during ICD-implantation. Damage can also be caused by the patient manipulating subcutaneous lead segments. In this report we describe a simple implantation technique which avoids the risks related to subcutaneous lead position and transmuscular subclavian vein puncture. In 16 patients, after preparation of the site of the device, we chose the subpectoral venous approach for the implantation of the leads from the ICD. Available approaches are the pectoral vein, the subpectoral section of the cephalic vein or a puncture of the subclavian vein which is fully visible from that size. Once the pectoral muscle has been sutured, the entire system is protected behind it. Apart from an early postoperative lead dislocation, no complications were observed in association with the operating technique within a mean follow-up period of 10.7 +/- 6.7 (SD) months. The advantages of this technique are as follows: There is no transmuscular subclavian puncture or exposure of the deltoideopectoral groove. The entire ICD system is situated under the pectoralis major muscle. Subcutaneous lead positions with the potential complications mentioned above can thus be avoided. The fact that a more complex technique and therefore a slightly lengthier operating time is required and that this technique is not particularly suitable for local anaesthesia may be regarded as disadvantages. Due to the small number of cases and the short follow-up period, a final conclusion on the application of this technique is not possible to date.

Adult↗
PubMed1981

A one-stage correction of mandibular defects using a split sternum pectoralis major osteo-musculocutaneous transfer.

This paper describes a technique of mandibular reconstruction using the sternal skin and the outer table of the sternum transferred as a compound osteo-musculocutaneous flap based on the pectoralis major muscle. The technique has been used for immediate reconstruction at the time of cancer ablation but it can equally well be used as a delayed reconstructive procedure.

Humans↗
PubMed2002

Expression of multiple troponin T isoforms in chicken breast muscle regeneration induced by sub-serous implantation.

Chicken fast-muscle type (F-type) troponin T (TnT) isoforms are classified into two types, leg-muscle type (L-type) and breast-muscle type (B-type), which are generated by exclusion and inclusion of exon x series-derived sequences in mRNAs, respectively. The B-type isoforms are further classified into neonatal breast-muscle (BN), young chicken breast-muscle (BC), and adult chicken breast-muscle (BA) subtypes. It is known that the multiple F-type TnT isoforms are transiently expressed in the breast muscle tissue during normal development. To examine whether the transition of the isoforms was fixed in muscle cell lineage, breast muscle pieces (pectoralis major) of 1-day old chicks were cultured under gizzard serous membrane of the same chicks for 60 days at the longest. TnT isoform expression of the implants was monitored by immunoblotting and immunostaining using anti-F-type TnT against both L-type and B-type isoforms, anti-exon x3 against only B-type isoforms, and anti-S-type TnT against slow-muscle-type (S-type) isoforms. Muscle fibers in the implant degenerated first, and then new myotubes expressing L-type isoforms were formed by the fusion of myoblasts from surviving satellite cells. When the maturation of the myotubes into myofibers proceeded, BN-, BC-, and BA-subtype isoforms were expressed in the order of developmental stage specific-manner, indicating that the order of appearance of these isoforms was fixed in muscle cell lineage. In immunostaining of the implants recovered on the 60th day after implantation, at least three kinds of the regenerated myofibers were observed, expressing mainly B-type, both B-type and L-type, and only L-type isoforms. The immunohistochemical results suggested that the regulation of alternative splicing of F-type TnT pre-mRNAs was different among individual myofibers, and that the regulation was programmed in myogenic cells, probably satellite cells, which were the primary source of the fibers.

Animals↗
PubMed2000

[Pharyngeal closure after pharyngolaryngectomy].

Pharyngolaryngectomy was performed in 53 patients. In 36 patients pharynx defect was less than 50% of pharynx circumference and it was closed without reconstruction. Larger pharynx defects were closed using platysma myocutaneous flap (13 cases), pectoralis mayor flap (3 cases) and free forearm flap with microvascular anastomosis (1 case). Healing results are presented in each group of patients.

Adult↗
PubMed1998

Muscle atrophy induced in broiler chicks by parts of Senna occidentalis seeds.

Senna occidentalis (formerly Cassia occidentalis) is a common contaminant of agricultural commodities. It is toxic to cattle and poultry, reportedly being responsible for skeletal myodegeneration in these animals. All parts of the plant present toxicity, but the seeds are the most toxic. The toxin(s) responsible for the myodegeneration have not been definitively identified, nor is it known which part of the seeds is most toxic. Intoxication by this plant leads to weight loss with considerable economic repercussions. The effects of the whole seed and of parts of S. occidentalis seeds (1% in commercial feed) were compared on the pectoralis major muscle of broiler chicks intoxicated from birth until 22 days of life. There were severe clinical signals and reduced body weight in birds that received the external tegment of the seed, whereas no adverse effects were observed in birds that received the whole seed or other parts of the seed. Histological and morphometric studies showed an intense muscle fibre atrophy (both type 1 and type 2 fibres were affected) in the group that received 1% external tegment. This study may be the first step to identifying the substance(s) involved in this pathological process.

Animal Feed↗
PubMed1999

Pectoralis major rupture during gait training: case report.

Rupture of the pectoralis major muscle is rare. The majority of cases have been reported in young, healthy athletes during strenuous activities such as weight-lifting, wind surfing, and football. The injury is thought to result from either a forceful contraction of the muscle applied to an immovable object or a sudden stretching force applied to the contracting muscle. This report describes a case of a 79-year-old man with a history of severe degenerative joint disease of the right hip and a recent left transtibial amputation secondary to a failed arterial bypass procedure. During prosthetic training the patient developed acute pain in the left shoulder and left axilla, which prevented him from further ambulation. Physical examination was consistent with a partial rupture of the pectoralis major. The causative factors of pectoralis major rupture in this patient are reviewed. To our knowledge, this is the first such case reported.

Aged↗
PubMed1987

An improved technique for immediate retropectoral reconstruction after subcutaneous mastectomy.

Subcutaneous mastectomy is becoming an operation of choice in certain cases of premalignant and other breast pathology. We describe a technique for simultaneous subcutaneous mastectomy and retropectoral implantation of a silicone prosthesis. Gentle blunt prepectoral, retromammary dissection is performed through an axillary incision as far inferiorly as the inframammary fold, where a fibrous bridge between the anterior surface of the pectoralis major muscle and the skin prevents dissection any lower. Through the same incision, the retropectoral space is dissected to about 5 cm below the inframammary fold. A second incision is made in the inframammary fold to join the retromammary plane of the first dissection. The gland is then dissected subcutaneously and removed through the inframammary incision. A silicone implant is introduced retropectorally through the axillary incision, thus avoiding splitting the pectoralis major. Satisfactory results have been obtained in 23 bilateral and 14 unilateral cases; it is important that the dissection be performed carefully in order to prevent the implant from riding up too high in its musculoaponeurotic sling.

Breast↗
PubMed1987

Treatment of winged scapula by pectoralis major transfer.

We report the transfer of the sternal part of the pectoralis major to the lower pole of the scapula in 15 patients with winged scapula. At follow-up after 1 to 16 years nine had a satisfactory result and were gainfully employed, though in four of these re-operation had been necessary. Two patients had fair results; the transplant functioned, but they had limited voluntary control. Four were failures: two had had paralysis of other shoulder girdle muscles in addition to the serratus anterior. The indications for the operation are discussed.

Adolescent↗
PubMed1997

Implantation of cardioverter defibrillator and pacemaker using the same pectoral quadrant.

We implanted a cardioverter defibrillator (ICD) together with a pacemaker system in three patients with ventricular tachycardia and bradyarrhythmias. Both systems (ICD and pacemaker) were implanted in the same left pectoral quadrant using a single skin incision and the subclavian and/or the cephalic vein. The ICD was implanted deep to the pectoralis major muscle, the pacemaker was placed subcutaneously in a more medial pocket. There were no technical difficulties during implantation or complications during follow-up.

Aged↗