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Soft-tissue profile changes concurrent with the orthodontic treatment.

Anthropologists have shown that the external covering made up of integument, adipose tissue, connective tissue, and muscle does not always distribute itself in a uniform, orderly manner. There are great variations in the amount and distribution of these soft-tissue elements. Therefore, a facial profile analysis that is limited to measurements on the hard skeletal structure would not appear to conform to the standards of accuracy if an assessment of the soft-tissue profile were required. The purpose of this investigation is to provide an understanding of the changes which occur in the soft-tissue profile during the orthodontic treatment concurrent with normal growth and development. At the present time, it is not possible to devise a set rule for differentiating a desireable from an undesireable soft-tissue facial profile. However, this should not prohibit the presentation of some reference material as an aid in the diagnosis and practice of orthodontics. In many instances evaluations of facial esthetics seem to be singularly influenced by the orthodontist's concept of a pleasing face. At present, the accomplishment of soft-tissue profile changes by dental movement is limited so it is very important to rely on proper timing of the orthodontic treatment through the pubertal growth period to achieve optimal profile changes.

Esthetics↗

Research on variation in dental occlusion. A "state of the art" workshop conducted by the Craniofacial Anomalies Program, the National Institute of Dental Research.

The following report on assessing research on variation in dental occlusion was based in part on a workshop conducted by the National Institute of Dental Research at the initiative of Richard L. Christiansen, Chief, Craniofacial Anomalies Program. The meeting was planned and developed by Robert J. Isaacson, Chairman, Touro M. Graber, Richard A. Riedel, and Richard L. Christiansen. This report is designed to provide a review of the achievements, directions, and needs of research concerning variations in dental occlusion. The workshop was held at the National Institutes of Health, Bethesda, Maryland, on Nov 22 and 23, 1972. The material presented by the workshop participants has been summarized and incorporated in this report. The subject of research related to the field of malocclusion was discussed in an article published in the American Journal of Orthodontics in January, 1971.

Dental Occlusion↗

Genetics in oral-facial growth and diseases.

Much debate has taken place over the relative importance of heredity and environment in the development of various diseases and conditions. Dental problems are not often easily categorised into either genetic or environmental, because most anomalies involve the interaction of both factors. Since many genetic disorders involve the orofacial region, the importance of the subject is paramount in dentistry to enable a proper understanding of the development of the various conditions and the treatment of patients presenting with those conditions. The incidence of newborn children with any congenital anomaly is estimated to be as high as 2 to 3 per cent, with more than half of these abnormalities, including minor manifestations, found in the head and neck region. It is therefore not unusual for dentists to be the first to recognise such conditions in their patients and be responsible for providing the necessary treatment. This paper describes many conditions, genetically or partly genetically mediated, which affect the oro-facial tissues, and offers descriptions by which the clinician can start to identify those conditions.

Environment↗

Anatomy and embryology in cephalothoracopagus twins.

Anatomical features are described in a case of cephalothoracopagus female twins with laterally fused heads. There was a single foregut, shared equally by the two individuals. The tracheae, lungs, hearts, livers, and gallbladders were also shared by the two individuals. They were located in the anterior and posterior regions of the joined bodies. These peculiarities occur in other cases of cephalothoracopagus twinning reported in the literature, and may have been caused by spatial problems in the developing twin embryos. In particular, each heart is considered to be a composite organ, formed by tissue from both individuals. The occipital region of the skull was double, but the remainder of the cranium was single. The oral cavity was divided in two by a midline mandibular body thought to represent the fused medial portions of two mandibles. Each compartment so formed contained a tongue. This midline body is considered responsible for a cleft lip and palate. Finally, we propose that anencephaly in this and other cases of laterally fused heads is associated with mechanical difficulty in closing the rostral neuropore.

Anencephaly↗

Facial deformity: a preventable disease?

By training, the orthodontist is uniquely qualified to be the primary monitor of facial growth. He should assess the mode of respiration at approximately two years of age and confer with the pediatrician, allergist and otolaryngologist to institute appropriate medical management of any developing problems. He must educate his colleagues in medicine and dentistry to recognize those conditions that can produce facial deformity. The primary care physician should appreciate that obstruction of the nasal airway is an important dysfunction. Medical and surgical intervention and, above all, good preventive management must be instituted to promote patency of the nasal airway. Allergy is a disease of modern man. It is possible that better prenatal care, breastfeeding, the avoidance of common allergens, and appropriate surgical and medical management to reduce the incidence of respiratory obstruction in growing children will result in fewer cases of cleft lip and palate and other craniofacial anomalies.

Airway Obstruction↗

A case of anterior open bite developing during adolescence.

Imaging studies have reported on the relationship between temporomandibular joint (TMJ) degeneration and facial deformity. These studies have suggested that mandibular growth is affected by TMJ degeneration, resulting in altered skeletal structure as mandibular retrusion. However, there are very few longitudinal case reports on TMJ osteoarthrosis (OA). Progressive open bite occurred in an adolescent patient with TMJ OA. Cephalometric analysis showed a downward and backward rotated mandible, and a labial inclination of the upper incisor. Magnetic resonance imaging showed internal derangement without reduction and erosion in the right and the left condyles. Although the cause of open bite is unclear in this case, tongue thrusting, and internal derangements in the temporomandibular joint were suspected as causes of the open bite.

Bone Resorption↗

Growth of the maxillary complex in the rhesus monkey (Macaca mulatta).

The growth of the maxillary complex of 36 rhesus monkeys (Macaca mulatta) was analyzed quantitatively and qualitatively during four defined stages of postnatal development (i.e., infant, juvenile, adolescent, young adult). At each stage, growth was observed during a 24 week period. Since some animals were observed during two successive stages of development, 47 periods of growth were studied. The incremental growth data were collected by superimposing serial cephalograms on cranial base implants and on maxillary implants. The largest increments of growth were observed in the infant animals and were successively less during the other periods studied. The horizontal growth component was more more prominent than the vertical component in all age groups. The contribution of sutural growth to the vertical displacement of the maxilla was greater posteriorly, leading to a rotation of the maxillary complex during growth. The occlusal relationship was maintained by selective bone remodeling in conjunction with dentitional migration.

Age Factors↗

[Development of the craniofacial structures and mandibular growth rotation: a longitudinal study with Enlow analysis (counterpart analysis)].

The aim of the present study was to evaluate the development of craniofacial structures in individuals with different actual mandibular growth rotation pattern. Enlow's counterpart analysis was used for this evaluation. The material was consisted 166 cephalometric films of 83 male and female subjects. A total of fourteen variables were employed and the data was analysed by various statistical methods. The vertical growth of middle cranial fossa and mandibular ramus as the equivalent of nasomaxillary complex was found to be the key sites in the determination of mandibular growth rotation pattern. Besides this, the sagittal location of maxilla and mandible related to the cranial base was different in backward and forward mandibular rotation patterns.

Cephalometry↗

Biomechanical and clinical considerations of a modified protraction headgear.

The choice of treatment of children with developing skeletal Class III malocclusions has always posed a dilemma. Chin cups and various types of reverse headgears with elastics have been used in the past to minimize the growth and development discrepancy of the midface and the mandibular bones. In the present article, a critique of commonly used protraction devices is presented. A modified protraction headgear design and the biomechanical considerations of its clinical use are presented in this study. The clinical results show that a modified protraction headgear with a chin cup helps in the correction of moderately severe Class III malocclusions by the anterior displacement of the maxilla and maxillary dentition, and possibly restricting or changing the direction of the growth of the mandible. This headgear can also be used to correct axial inclinations and/or mesial displacement of posterior teeth.

Activator Appliances↗

Effect of nerve repair after unilateral partial facial paralysis on craniofacial growth and development.

The effect of partial transection, coaptation, and freezing of the left facial nerve on craniofacial growth and development was investigated. Twelve-day-old New Zealand White rabbits were randomly assigned to four groups: control group (n = 15), nerve ablation group (n = 15) with a surgically induced partial facial paralysis, nerve coaptation group (n = 15) with a surgically induced partial facial paralysis treated by immediate microsurgical nerve coaptation, and nerve freezing group (n = 13) with a freezing-induced partial facial paralysis. All animals were operated on at the age of 12 days; follow-up evaluations were performed at the ages of 2 months (end-point prepubertal growth) and 6 months (full grown). Computerized dorsoventral roentgencephalometric analysis and computer tomographic three-dimensional volumetric measurements were performed at both ages. Roentgencephalometric analysis revealed that the growth disturbances of the nerve ablation group and the nerve coaptation group were analogous. In contrast, in the nerve freezing group, hardly any growth disturbances as compared with the control group were seen. The CT volume measurements revealed a significant left-right difference in maxillary volume at the ages of 2 and 6 months in the nerve coaptation group as compared with the control group. Muscle histomorphometric analysis revealed a shift in muscle fiber composition in the nerve coaptation group and the nerve freezing group, with an increase of type I fibers at the cost of type IIA fibers. This shift was significantly less pronounced in the latter than in the former. Nerve histomorphometric analysis revealed a significant increase in the number of nerve fibers in the nerve coaptation group as compared with the control group. In the nerve freezing group, the increase in the number of nerve fibers was not significantly different as compared with the control group and the nerve coaptation group. Both the equivalent diameter and the myelin area were equally reduced in the nerve coaptation and nerve freezing groups. Thus, the nerve coaptation group and the nerve freezing group did not differ significantly in the extent of nerve recovery, although they differed in the extent of muscle recovery. The extent of muscle recovery, in turn, was related to the extent of abnormal craniofacial growth and development. Indeed, the growth and development were hardly abnormal in the nerve freezing group and as abnormal as after untreated paralysis in the nerve coaptation group. Therefore, factors related to nerve regeneration, other than those assessed by nerve histomorphology, were considered to be responsible for these differences between both groups. The duration of the denervation time was regarded to be considerably shorter in the nerve freezing group than in the nerve coaptation group, resulting in the observed improved muscle recovery. The difference in the degree of axonal malalignment between both groups was considered to be negligible, because of the tolerance toward axonal malalignment at neonatal age.

Animals↗

[Relationship between growth and tooth eruption. Relationship between growth and physical development and eruption of first permanent molars in São Paulo students].

In order to verify the relationship between the children's growth and their teeth's emergence the authors surveyed 1278 school children in São Paulo's Ipiranga District, 1024 from government controlled schools and 254 from a private school, finding their weight and height anthropometric measures related to the emergence of permanent molars. Their ages were four (completed) to eight incompleted). It was verified that the children from the private school presented in average higher weight and height than those from government controlled schools as well as higher percentages of first permanent molars erupted, in both the sexes and in all the age groups and that there was a positive association between the children's growth and their teeth's emergence.

Body Height↗

Craniofacial development in children with unilateral clefts of the lip, alveolus, and palate treated according to four different regimes. III. The soft tissue profile at 16-18 years of age.

The soft tissue profiles of 85 16-18 year old children with unilateral clefts of the lip, alveolus, and palate treated according to four different regimes were studied using lateral skull radiographs. Regimes that included secondary bone grafting to the alveolus in the mixed dentition gave better convexity of the soft tissue profile (excluding the nose) and better soft tissue sagittal jaw relationships compared with treatment regimens that included primary bone grafting. The soft tissue profile in regimes that excluded bone grafting was almost as favourable as those in regimes in which bone grafting was done during the mixed dentition.

Adolescent↗

Growth changes in internal and craniofacial flexion measurements.

Growth changes in both internal and craniofacial flexion angles are presented for Pan troglodytes, Gorilla gorilla, and modern humans. The internal flexion angle (IFA) was measured from lateral radiographs, and the craniofacial flexion angle (CFA) was calculated from coordinate data. Stage of dental development is used as a baseline for examination of growth changes and nonparametric correlations between flexion angles and dental development stage are tested for significance. In Gorilla, the IFA increases during growth. The IFA is relatively stable in Pan and modern humans. Pan and Gorilla display an increase in the CFA. However, this angle decreases during growth in modern humans. Flexion angles were derived from coordinate data collected for several early hominid crania. Measurements for two robust australopithecine crania indicate strong internal flexion. It has been suggested that cerebellar expansion in this group may relate to derived features of the posterior cranial base. In general, australopithecine crania exhibit craniofacial flexion intermediate between great apes and modern humans. The "archaic" Homo sapiens specimen from Kabwe is most similar to modern humans.

Animals↗

Relationship between lower arch spacing/crowding and facial height and depth.

Previous research into the origins of lower incisor crowding have not yet established the part played by skeletal morphology in its development. Longitudinal cephalometric records of twelve cases with spaced lower teeth were compared with those of twelve moderately crowded cases and twelve severely crowded cases. Significant differences were found between the three groups. These suggested that crowded cases are more likely to have larger Frankfort--mandibular and occlusal plane angles and shorter posterior face height and mandibular body. Both lower incisors and mandibular symphysis were found to be less protrusive in the crowded cases. During the period of study, from 8 years to 14 years, mandibular prognathism increased more in the spaced cases, although labial inclination of lower incisors increased less in these subjects.

Adolescent↗

Growth patterns of the face: a morphometric study.

Age-related growth changes in the face and the relationships between its parts were calculated by using three vertical, two horizontal, and two projective surface measurements from 1,594 healthy North American Caucasians between 1 and 18 years of age. By 1 year, the width of the mandible was highly developed (80.2%) while its height reached only 66.6% of the eventual adult size. The mandible's height and width showed significant development between 1 and 5 years, while the face height, upper face height, face width, and the two face depth measurements exhibited continuous gradual growth after 5 years of age. In general, the face matured between 12 and 15 years in males and 2 years earlier in females. At 12 years, the upper face height, the mandible height, and the width of the face reached their mature size in females. At 15 years, the face height, mandible height, face width, and the depth of the mandible reached maturity in males.

Adolescent↗

[Vertical control and orthopedic therapy].

Control of the vertical development of the face is a key element in assuring the success of orthopedic treatment, as much for its effects on anterior vertical dimension as for its influence on correction of the sagittal discrepancy between the jaws. An effective management of this control demands respect for the equilibrium between posterior and anterior face, as described by Schudy. The authors review the details of the application of orthopedic therapy on the different elements of this equilibrium and then, present the modalities of vertical control appropriate to each appliance.

Cephalometry↗

Effect of radiation injury on the growing face.

The literature on the effect of ionizing radiations on developing and rapidly growing tissue has been reviewed, and the effect especially on children who received radiation therapy in the Clinic for Maxillo-Facial and Plastic Surgery of the University of Dusseldorf for various tumours of the head and neck presented. Our findings indicate that we do not yet know the minimal irradiation dosage that may cause growth retardation in infants and children. It has therefore been suggested that surgery should be more frequently considered in the treatment of childhood tumours, since this caused less side effect, and reconstructive surgery is today able to do much for patients who have had parts of their jaws resected.

Adolescent↗

[Could facial growth be influenced by neuromuscular therapy? Should one propose respiratory therapy or is it preferable to do nothing?].

For at least a century, controversy has existed in the dental and medical fields regarding the level of significance to be ascribed to a predominantly oral breathing pattern on craniofacial growth and development. One school of thought holds that severely limited nasal breathing produces physiologic postural changes in the head and neck, which would have a direct effect on craniofacial growth, leading to the so-called Long Face Syndrome or Adenoid Facies. This point of view implies that significant growth changes can be obtained by therapeutically altering the oro-facial neuro-muscular behaviour of the patient. The purpose of this paper is to critically analyze the clinical and experimental evidence regarding this controversy. Based on our present state of knowledge, one can't but conclude that neuro-muscular therapy or reeducation as a sole therapeutic measure is only of limited clinical importance.

Animals↗