Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “sequelae”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,279 records · Page 71Linked to original sources
PubMed1987

Sequelae of orbital fractures.

Many injuries and complications of orbital fractures are instantaneous and unpreventable, some develop over time, and some are a result of surgery. Most complications can either be managed or prevented and are anticipated based on the fracture location and size. A thorough search for probable complications is mandatory, especially ocular injuries and intracranial complications. Most patients are carefully followed for 7-14 days, and the significant residual sequelae are managed. Some complications, however, require urgent care.

Eye Diseases↗
PubMed1988

Vulvovaginal sequelae of Stevens-Johnson syndrome and their management.

We describe a woman with Stevens-Johnson syndrome, a life-threatening form of erythema multiforme characterized by bullae formation, extensive mucosal damage, and systemic toxicity, and known to be triggered by various drugs, infections, ingestants, or contactants. Serious complications have been reported in most body systems, including cases of permanent damage to the urogenital tract. Three methods of surgical treatment for severe vaginal complications, depending on the degree of vaginal mucosal damage, are described, including the successful treatment of our patient, who had vaginal adenosis, endometriosis, and severe stenosis from this disease. Methods of therapy are presented for possible prevention of severe vaginal sequelae from Stevens-Johnson syndrome.

Adult↗
PubMed1988

[Late sequelae of leukemia in childhood: psychosocial aspects].

As more children are now being cured of cancer, the physical and psychosocial consequences of cancer and its treatment become increasingly important issues for the pediatric cancer survivor. Information is accumulating on the sequelae of childhood cancer, especially on the medical side-effects of cancer treatment. Although considerably less information is available on the psychosocial adaptation of the long-term survivor, existing studies reveal that cancer survivors are at risk of developing adjustment problems. Until now no study has addressed the psychosocial functioning of the family of the long-term survivor. Preliminary results of our recent pilot study on this issue indicate that parents as well as siblings can experience ongoing problems in coping with the cancer experience.

Adaptation, Psychological↗
PubMed1988

[Treatment of sequelae of basedowian exophthalmos].

Treatment of sequelae of ophthalmopathy of Basedow's disease, essentially exophthalmos, oculomotor disorders and upper eyelid retraction, is of particular importance because of the functional and esthetic problems presented. Improvement in the different symptoms can be obtained by surgical treatment, but patients must have been perfectly stable with respect to both the thyroid and ophthalmologic plan for at least 6 months. It marked exophthalmos exists this is treated initially by orbital enlargement. Oculomotor problems are then resolved and finally treatment is terminated by surgery to eyelids. Very satisfactory functional and esthetic results are obtained.

Exophthalmos↗
PubMed1988

Dysphagia in postpolio sequelae: report of three cases.

Findings on three postpolio sequelae patients referred for swallowing evaluations are presented. The first patient, a 67-year-old man more than 60 years post onset of polio, complained of frequent coughing and the sensation of foods becoming stuck in his throat during meals. Videofluoroscopic swallowing exam revealed reduced pharyngeal peristalsis and liquid pooling in the pyriform sinus. The second patient, a 59-year-old woman, was more than 30 years post onset of polio and was referred because of progressive dysphagia and hoarseness in the past three years. Videofluoroscopy revealed reduced strength of the oral musculature and reduced pharyngeal peristalsis with pooling of liquids in the pyriform sinus. The last patient, a 50-year-old woman more than 40 years post onset of polio, reported having difficulty with foods sticking in her throat. Swallowing exam revealed a delayed swallowing reflex and reduced pharyngeal peristalsis. Although none of the patients was observed to aspirate, all were considered to be at risk because of the gradual build-up of foods in the pharynx. Noninvasive management procedures and the importance of stress testing the swallowing mechanisms of such patients are discussed. Longitudinal follow-up with these individuals is recommended.

Aged↗
PubMed1988

Pain scores and ventilatory and circulatory sequelae of epidural morphine in cancer patients with and without prior narcotic therapy.

Pain scores and respiratory and circulatory sequelae of epidural morphine were studied in 25 patients with cancer, classified into two groups: 15 with and 10 without a history of previous narcotic analgesic therapy. Morphine, 2.5 mg initially and 5.0 mg 12 hours later, was given through an indwelling lumbar epidural catheter. Pain scores, heart rate, blood pressure, respiratory rate and minute volume, arterial PO2 and PCO2, and arterial pH were measured for 24 hours. Both groups had the same degree of analgesia after each epidural dose, suggesting that local morphine concentrations seen with epidural administration may be sufficient to overcome any degree of tolerance that may have developed at the spinal level during previous systemic narcotic administration. Statistically significant dose-dependent hypoventilation and concomitant respiratory acidosis were seen in both groups, the changes being significantly greater in opiate-naive patients. These results demonstrate that the ventilatory depressant actions of opioids are attenuated but not eliminated in narcotic-familiar cancer patients and that epidural narcotics are as effective in relieving pain in narcotic-naive patients as in patients previously exposed to narcotics for relief of cancer pain.

Adult↗
PubMed1986

Physiologic principles and clinical sequelae of cardiopulmonary bypass.

CPB has been a key element in the safe and effective practice of cardiac surgery since its inception more than 30 years ago. Refinements in the apparatus, methods of tissue preservation, and innovations in technique have lowered the morbidity and mortality rates from these procedures. Despite these factors, the pump-oxygenator apparatus itself and the processes of hemodilution, hypothermia, and anticoagulation, which are intrinsic to its operation, effect temporary physiologic derangements in organ system functions. Although all of these phenomena resolve spontaneously, some require treatment while others do not. Therefore, appropriate clinical management of this group of patients, must be based on an understanding of CPB techniques and the anticipated physiologic sequelae. Hypertension should mostly be controlled because high systemic vascular resistance exacerbates the tendency for bleeding and stresses fresh anastomoses. Volume, urine flow, and potassium loss must be monitored strictly and treatment initiated promptly. Cardiac dysfunction requires cautious, individualized pharmacologic, and sometimes mechanical support in the perioperative and postoperative periods. Laboratory values should never be treated routinely. CPB is not without intrinsic risk of serious clinical complication, and these must be anticipated after surgery. The potential for complication increases when CPB exceeds 2 hours and rises sharply when pump time is prolonged more than 3 to 4 hours. Excessive pump time exacerbates blood trauma, produces abnormal capillary membrane permeability, and predisposes the patient to tissue anoxia. The potential for embolism and pulmonary complications is increased. Permanent organ system damage can be avoided through strict attention to myocardial and tissue preservation, meticulous filtration, precise technique, and avoidance of prolonged extracorporeal circulation.

Blood Pressure↗
PubMed1986

[Lymphocyte activation by bacterial biostructures: precursor of infection-induced immune phenomena and sequelae? I. lymphocyte reactions to A-streptococci].

The pathogenesis of the nonsuppurative sequelae of bacterial infections, e.g. rheumatic fever (RF) following A-streptococcal infection and seronegative spondarthritis (SS) following enterobacterial infection, is thought to be related to 1. an unusual persistence of infection, and/or 2. direct toxic effects of bacterial toxins, and/or 3. an abnormal immune response to the inital infection. Additionally, modern working hypothesis center around more recent findings concerning the genetic predisposition (for which there are now markers in both diseases) and the various immunologically active biostructures of the bacteria. These structures consist chiefly of a. crossreactive (CR) antigens, i.e. common or similar epitopes in both bacteriae and mammalian tissues, and b. polyclonal cell activators, e.g. the polyclonal B-cell activator (PBA) which induce immunologically many nonspecific resting B-cell clones to mature into Ig secreting cells. In this paper the lymphocyte response to a wide range of bacterial cell preparations is described. Blood lymphocytes from both RF and SS patients respond to the disease-precipitating microorganism more rigorously than the controls. There are several lines of evidence that the heightened response is genetically determined. However, there are no obvious facts which can confirm the idea that the so-called cross-reactive antigen preparations induce a specific cell response to CR antigens. On the contrary, such crude cell membrane preparations are obviously composed of an antigenic mosaic and of polyclonal cell activators: lymphocytes from healthy blood donors and even from newborns respond with lymphokine production, blastogenesis and Ig secretion under certain circumstances.(ABSTRACT TRUNCATED AT 250 WORDS)

Antigens, Bacterial↗
PubMed1987

[Sclerosing cholangitis and biliary sequelae of hydatid cyst of the surgically treated liver].

Worldwide literature and ten or so personal cases are reviewed as a basis for distinction or intrication of two aspect of post-hydatid sclerosing cholangitis; that of a localized lesion of diffuse lesions of the biliary tract. In both cases the action of the hydatid cyst is not due to toxins but to pressure on biliary duct walls, very variable according to site and size. This local action may be the only cause, provoking a specific type of lesion, a true sequela of an incomplete or delayed operation. In certain regions, or in the presence of biliary stasis and angiocholitis, passage of hydatid fluid into biliary tracts, normally tolerated by healthy biliary pathways, leads to a diffuse sclerosing cholangitis. The serious consequence of this eventuality is proved by the failure of many treatments, with subsequent inevitable liver transplants. Clinical circumstances and data explaining this complication allow necessary precautions to be taken. Furthermore, early treatment of hydatidosis or as radical as possible therapy for advanced lesions is curative of localized forms of the disease.

Bile Ducts↗
PubMed1977

Secondary hyperparathyroidism and its sequelae in renal transplant recipients. Long term findings in a series of conservatively managed patients.

The prevalence and duration of secondary hyperparathyroidism in 42 renal transplant recipients, and the sequelae of this condition, were studied. Immediately before transplantation, an elevated PTH-value was recorded in 76% of the patients, postoperatively there was a marked drop. Early after successful transplantation, 57% of the patients had hypercalcemia. At follow-up 3 years later, moderate hypercalcemia persisted in half of the patients but only 3 patients had significantly elevated PTH. The quality of renal graft function was not inferior in the hypercalcemic patients. Subperiosteal bone resorption and soft tissue calcifications were more common among the hypercalcemic patients. Our data suggest that secondary hyperparathyroidism can be managed conservatively in most renal transplant recipients. If progressive bone changes occur, surgical removal of parathyroid tissue should be considered.

Child↗
PubMed1987

[Late sequelae following laterobasal fractures, therapeutic and forensic viewpoints].

Report on two cases of temporal bone fracture with unilateral profound deafness and vestibular dysfunction. The other ear was apparently not involved. After 4, respectively 18 years, a sudden hearing loss occurred in the second ear, fluctuating and associated with acute vestibular symptoms. On operation we found in the first case a perilymph fistula in the round window, in the second case a gaping fracture in the promontory. A retrospective study of 527 cases of "sudden hearing loss" revealed 11 more cases with similar histories that must be regarded as sequelae of the head trauma. The latency between trauma and onset of hearing loss in the second ear ranged from 4 to 33 years. Discussion of the pathomechanism of the trauma, therapeutic and medico-legal issues.

Adult↗
PubMed1978

[Complete repair in one stage of the sequelae of unilateral total hare lip (author's transl)].

The sequelae of hare lip, of mixed origin, malformative and surgical, require careful analysis of the deformities present in order to ensure their correction. The basic concept is replacement of the cleft in its initial position, i.e.: --re-opening of the cleft, --exposure of the bony edges, --excision of scar tissue. Restoration is then performed starting deep and working upwards, with primary attention paid to the skeleton with the complex concern of: --normalisation of the underlying bone and of occlusion, --re-establishment of oro-nasal muscular equilibrium, --esnuring nasal ventilation. without neglecting the overall morphology. With this in mind, complete repair in one stage is most likely to result in a harmonious overall result.

Bone Transplantation↗
PubMed1978

Neurologic sequelae in infants with intrauterine growth retardation.

The literature on neurologic sequelae in infants with intrauterine growth retardation (IUGR) is reviewed. In many studies this term is used for only those infants who have a birthweight (BW) below the 10th percentile and are labeled small for gestational age (SGA). The etiology of IUGR can often be correlated with a characteristic pattern of in utero growth and a subsequently predictable pattern of postnatal growth and/or developmental outcome. The concept that certain premature infants who are appropriately grown for gestational age (AGA) but whose birth weights fall below the 50th percentile may have IUGR is supported by the analysis of data from this study. In attempting to predict the neurologic outcome, it may be more helpful to recognize etiologic factors such as sleep disturbances than to analyze infants by birth weight gestational age groups.

Adolescent↗
PubMed1986

[Sequelae of craniocerebral injuries and status of nonspecific systems of the brain].

A total of 100 patients with sequelae of head traumas (concussion, contusion) were examined for the status of nonspecific cerebral systems. Forty healthy subjects comprised a control group. Combined examination of vegetative, electropolygraphic and neuropsychological systems made it possible to identify a syndrome of psychovegetosomatic disregulation in patients with a history of neurotrauma. It is suggested that the above syndrome is the key mechanism of head trauma consequences and that its development is related to dysfunction of nonspecific cerebral systems.

Adolescent↗
PubMedDate not supplied

Testicular atrophy as a sequela of inguinal hernioplasty.

Testicular atrophy is a sequela of inguinal hernioplasty which angers men of all ages. The complication is due to thrombosis of the veins of the spermatic cord from the trauma of surgical dissection intrinsic in all inguinal hernioplasties and is not due to incorrect reconstruction of the inguinal rings or to some intangible infection. Trauma to the cord from surgical dissection can be minimized and the incidence of testicular atrophy reduced by leaving, whenever possible, the distal part of all but the smallest of indirect inguinal hernia sacs in place, undissected and attached to the cord.

Atrophy↗
PubMed1986

[An anatomo-clinical case of sequelae of acute encephalopathy. Infantile spasm with hypsarrhythmia].

Clinico-pathological studies of West syndrome are rather rare. A case of sequelae of acute encephalopathy which involved a nine-month-old boy with post-mortem data is reported. Birth and postnatal development had been normal until the onset of illness. Laboratory examinations ruled out bacterial or viral meningo-encephalitis and metabolic disorders. After the recovery from a coma lasting several days, spastic quadriplegia, severe mental retardation and intractable epileptic attacks were present. The latter were made of tonic spasms and myoclonic seizures. EEG records showed hypsarrhythmia. Neuropathological examination revealed almost symmetrical bilateral cystic cavities in the pontine tegmentum and lateral nuclei of both thalami. The corpus callosum was very thin. No finding suggested a congenital anomaly. In a search of the pathological basis for infantile spasms, this case was compared with the published data. It would appear that the lesions of the pontine tegmentum play a significant role in the pathogenesis of hypsarrhythmia or infantile spasms.

Acute Disease↗