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At least 1,279 records · Page 71Linked to original sources
PubMed2002

Needed: models of biotechnology intellectual property.

Although never uncontroversial, intellectual property rights in biotechnological innovation are once more the focus of intense debate. The debate has yet to reach any result, largely because of several important errors in the way that various disciplines approach it. These errors include making assumptions without empirical basis and conflating various intellectual property regimes. What is needed is a transdisciplinary integrated method to correct these errors. Such a method can be implemented through the construction of alternative models of intellectual property protection designed to balance the various social, ethical and economic constraints that affect biotechnology.

Biotechnology↗
PubMed2006

[Cough as a symptom--clarify or treat empirically?].

Cough is one of the most prevalent symptoms for which patients seek the attention of their physicians. Cough may serve as a protective reflex but can also impair social well-being and can profoundly and adversely affect patient's quality of life. Short and self-limited cough often does not require therapy, whereas prolonged cough is bothersome and should prompt further workup. If possible, the underlying cause should be identified and treated accordingly. Often, the patient history helps to establish a working hypothesis, such as possible post-nasal drip syndrome or gastroesophageal reflux as a cause. Asthma, another frequent cause of prolonged cough, is readily diagnosed in most cases. The response to empirical therapy often "confirms" a suspected etiology, if not, extensive workup involving function testing such as bronchoprovocation, radiology, endoscopy, and extended search for exceptional causes is warranted. Productive cough is often related to a bronchopulmonary disease, whereas an irritant cough is often of an extrapulmonary origin.

Chronic Disease↗
PubMed2005

Community violence and urban families: experiences, effects, and directions for intervention.

The purpose of this study was to understand the impact of community-level stressors (particularly violence), coping strategies, and resources to prevent exposure to violence or to mitigate its effects in an inner-city community. Parents and children participated in focus groups, and children also completed standardized instruments. In the focus groups, parents and children identified several areas of concern related to "helpers," schools, community safety, and emotional distress. They identified protective resources including intensive monitoring and social supports. Fifty percent of the children met criteria for Posttraumatic Stress Disorder (PTSD), and another 21% met criteria for partial PTSD. The mental health issues in children living with ongoing community violence necessitate that researchers use a qualitative approach to inform future interventions.

Achievement↗
PubMed2006

College student alcohol use in context: the utility of goal constructs.

Alcohol use occurs in the context of multiple goals that college students develop, pursue, and modify in their transition to adulthood. Consequently, the assessment of goal constructs provides a valuable tool for understanding the developmental context of college drinking. Conceptualizing student alcohol misuse in terms of its effects on valued goals has a number of advantages for understanding personality risk and protective factors, clarifying the contributions of social and environmental influences, and developing motivation-based interventions.

Adolescent↗
PubMedDate not supplied

Health-care utilization among mothers and infants following cocaine exposure.

OBJECTIVE: To examine utilization of health-care resources among mothers and infants following cocaine use during pregnancy. DESIGN: Prospective observational study. SETTING: Four clinical sites. PATIENTS/METHODS: Medical and social services resource use was examined among 8514 mother-infant dyads, 1072 of whom used cocaine and 7442 who did not. Use was stratified by <1500 g and >1500 g birth-weight strata to differentiate the low birth weight from the larger weight group adjusting for site, infant gender, and maternal race and education. OUTCOME MEASURES: Resource use evaluated among mothers included prenatal care, hospitalizations, medications and mode of delivery. Resource use for infants included therapies, procedures and length of stay. RESULTS: Fewer cocaine-exposed women, compared to those in the nonexposed group, had prenatal care or used medications during pregnancy in both <1500 g category 0.10 (0.04 to 0.22) (OR (99% CI) and 0.26 (0.10 to 0.65), respectively, and in the >1500 g category 0.14 (0.11 to 0.19) and 0.61 (0.49 to 0.74), respectively. Length of hospital stay for social reasons and referrals to child protective services were increased in cocaine-exposed infants in both <1500 g category 66.8 (4.38 to 999.9) and 77.4 (17.64 to 289.13), respectively and in the >1500 g category 70.74 (41.73 to 119.94) and 125.88 (81.78 to 193.77), respectively. In addition, among >1500 g cocaine-exposed infants, length of stay in neonatal intensive care unit was increased 1.53 (1.16 to 2.02) as was therapies 1.76 (1.45 to 2.13), procedures 1.50 (1.23 to 1.83), need for formula feeds 5.45 (2.28 to 13.02) and intravenous fluids 1.50 (1.19 to 1.87), CONCLUSION: Cocaine exposure has no deleterious or protective effects on medical resource needs of <1500 g infants or their mothers. Resource needs reflect those of morbidity of being born premature. The increase in health-care resources for >1500 g cocaine-exposed infants for surveillance and monitoring in the absence of an increase in congenital anomalies should be discouraged.

Abnormalities, Drug-Induced↗
PubMed2001

Is dementia a mental illness?

OBJECTIVE: To examine whether dementia is a mental illness. METHOD: An analysis of decisions in the Supreme Court of New South Wales that dementia per se was not a mental illness in terms of the 1958 Mental Health Act. A brief review of the extrusion of other diseases from psychiatry. RESULTS: Concepts in legislation are based on a dichotomy between mental infirmity and mental illness that has changed over time. This change is the result of shifting perceptions about the basis of illness and disease and the causation of mental symptoms. Mental health legislation is aimed as much at social control of feared behaviour as protecting the ill/incompetent. Guardianship legislation offers a more holistic response that better meets the patient's needs and could be extended to supplant mental health legislation. CONCLUSIONS: Dementia's departure from mental illness reflects psychiatry's continuing marginalization within medicine on an outdated mind/body or illness/disease split. This underlines one of the psychiatrist's roles as the vehicle to 'medically' explain abnormal behaviour. This model means that behaviour, once explained in terms of disease as opposed to illness, can be moved from the direct responsibility of psychiatry into other areas of medicine. Paradoxically, this suggests that the future of psychiatry will be in a completely different direction from its current biological focus.

Dementia↗
PubMed2026

Silent crises in the COVID-19 pandemic shadow: a six-year medico-legal review of non-lethal intimate partner violence in Morocco.

Intimate partner violence (IPV) is a major global public health concern and one of the most prevalent forms of gender-based violence, with significant consequences. This study analyzes non-lethal IPV cases reported to a medico-legal unit of Casablanca between 2018 and 2023. Data from 4,784 female victims were reviewed, focusing on socio-demographics, violence types, perpetrator relationships, and judicial involvement across the pre-COVID, peak COVID-19, and post-COVID periods. Married women represented 59.2% of victims. Physical violence predominated (83.1%), while sexual violence was underreported (14.7%). The year 2020 marked a sharp increase in reported non-lethal IPV cases (n&#x2009;=&#x2009;1,005), correlating with pandemic confinement. Among married women, judicial requisition (legal request for forensic examination) and medico-legal certification (medical documentation for judicial use) rates were high (81.5% and 81.0%, respectively). Post-pandemic years declined moderately but remained above pre-COVID levels. International comparison confirmed a global rise in IPV during COVID-19, with Morocco displaying comparatively higher rates of medico-legal documentation and judicial involvement. IPV in Morocco is entrenched and intensified by COVID-19. While the medico-legal system is robust in documentation, the system must evolve by integrating systematic psychological assessment into medico-legal evaluations, standardizing certification and referral protocols, and strengthening coordination between medico-legal, health, and social support services to improve victim protection.

Humans↗
PubMed2003

Internet gambling: issues, concerns, and recommendations.

The influence of technology in the field of gambling innovation continues to grow at a rapid pace. After a brief overview of gambling technologies and deregulation issues, this review examines the impact of technology on gambling by highlighting salient factors in the rise of Internet gambling (i.e., accessibility, affordability, anonymity, convenience, escape immersion/dissociation, disinhibition, event frequency, asociability, interactivity, and simulation). The paper also examines other factors in relation to Internet gambling including the relationship between Internet addiction and Internet gambling addiction. The paper ends by overviewing some of the social issues surrounding Internet gambling (i.e., protection of the vulnerable, Internet gambling in the workplace, electronic cash, and unscrupulous operators). Recommendations for Internet gambling operators are also provided.

Behavior, Addictive↗
PubMed2000

HIV counselling--a luxury or necessity?

WHO and UNAIDS have consistently promoted HIV counselling as a routine part of HIV testing in developing countries. Nevertheless, in many countries counselling is not considered a crucial accompaniment of testing services, and patients are tested without access to counselling during and after testing. Thus, information on the need for and results of counselling is needed to convince policy-makers and service managers to give greater priority to the development of counselling services. This qualitative study describes informational, social and emotional needs and problems of newly diagnosed seropositive patients attending public health services in Zimbabwe. Their basic factual information on HIV/AIDS was reasonable, but many patients equalled HIV to AIDS and conceptualized their infection as 'social and physical death'. This seriously impeded their capacity to use knowledge of their test results in a constructive way, and stimulated coping by denial and/or secrecy about their HIV status. These avoidant coping strategies discouraged clients from using condoms, seeking social support and taking measures to protect their vulnerable health. The complex and changing nature of clients' needs indicates that common short-cuts in counselling (e.g. giving brief information before and after the HIV test) are seriously flawed as a strategy to prepare clients for effective coping. Comprehensive pre- and post-test counselling are an essential preparation for coping effectively during and immediately after testing. Availability of supportive counselling beyond this first phase is essential to assist clients with needs and problems which will appear over time. Development of counselling interventions should be guided by research into their effectiveness and by national policy guidelines. Replacing fear-inducing HIV campaigns with interactive, constructive information about HIV prevention and care will increase the preparedness of the community as a whole for effective living with HIV.

Adaptation, Psychological↗
PubMed2006

Building community involvement in cross-cultural Indigenous health programs.

OBJECTIVE: To gain preliminary knowledge about issues identified by Native health investigators who would encourage greater community involvement in Indigenous health programs and research in Canada, Pacific Rim, and the United States. DESIGN: A pilot/feasibility study, August 2001-April 2002. SETTING: Indigenous health agencies and institutions in New Zealand, Australia, Canada, and the United States. PARTICIPANTS: Thirty-six health professionals from rural and urban health centers participated, which resulted in 10 group and four individual interviews. Subjects included program managers, clinical physicians, and health researchers. Approximately 58% of the subjects self-identified as Indigenous. RESULTS: Three overarching themes emerged from the interview data: (i) integration of cultural values of family and community into health provision; (ii) emphasis on health education and prevention programs for Indigenous youth; and (iii) indigenous recognition and self-determination in health delivery and research. CONCLUSIONS: To improve and promote community involvement in primary health programs and services for Indigenous people involves a long-term social and political commitment to health protection on a national and an international level, as well as the understanding that research methodologies and health interventions must explicitly involve culturally appropriate values and behaviors that are implemented by Indigenous people.

Australia↗
PubMed1988

The future of the de minimis concept.

How low is low enough? Is "close to zero? Does detectability define importance? These and similar questions are addressed in this paper, which considers the concept of a "practical zero" or de minimis level of radiation and the future applications of that concept. After defining the concept and some widely used terms and summarizing the current status of the de minimis approach, this article surveys the activities of standards-setting and regulatory bodies throughout the world and their possible future approaches to applying the de minimis concept. Applications include conventional disposal of very-low-level wastes, ocean dumping, decontamination and decommissioning guidelines, and truncation of as low as reasonably achievable and collective dose calculations. Implications in areas beyond low-level radiation control are also addressed. These areas include nuclear accident risks and the risks associated with use of hazardous materials. The application of the de minimis concept to risks of all types is discussed, with a particular emphasis on the risks of carcinogenesis. The paper also presents a summary of methods for quantitatively setting actual levels that are deemed de minimis in specific cases. Finally, the problems inherent in a de minimis approach are discussed and an attempt is made to predict future developments.

Government Agencies↗
PubMed1998

Ethical issues in radiation protection, continued.

Shrader-Frechette and Persson (1997) reviewed ethical thinking on (1) Equity vs. Efficiency, (2) Health vs. Economics, (3) Individual Rights vs. Societal Benefits, (4) Due Process vs. Necessary Sacrifice, and (5) Stakeholder Consent vs. Management Decisions. This discussion offers reasoned conclusions pertaining to these five topics. In addition, ethical aspects are discussed as to (6) Psychological Harm Through Fear of Radiation, (7) Economical-ecological Harm Through Fear of Radiation, and (8) Science: the Question of Truth.

Ethics↗
PubMed1981

Can mother-infant interaction produce vulnerability to schizophrenia?

Schizophrenia is regarded as a final common behavioral syndrome which may be arrived at though a variety of routes. Even with a probably genotype, environmental influence seems necessary for the phenotype to appear. The problem concerns the likelihood of an early experience-induced sequence of events within the person of infant and later adult vs. a continuing pathogenic environment. Either may or may not interact with a continuing genic factor(s) as a source of vulnerability. Vulnerability is here, then, viewed as epigenetically evolving via individual-environment transactions throughout life (although with major impacts from conception through adolescence). At any point, therapeutic intervention may preclude or minimize the actualization of the pathogenic potential. It may begin during pregnancy, with attention to such factors as diet, drugs, physical stress, and illness, influencing fetal development and obstetrical manipulations and the birth process. All influence earliest mother-infant interaction from the point of view both of the infant's evocation of maternal behavior and maternal responsivity. Therapeutic interventions also include attention to the multigenerational context of earliest interaction, with special reference to a woman's relationships with her own mother. At every point, nonspecific protective or pathogenic factors such as social support or stressful precipitating events may become important. Socioeconomic status appears to have a powerful nonspecific influence as the core of a cluster of factors which exert an enduring influence from infancy to adulthood. A continuing specific factor may reside in distorted communicative reciprocity between parent an child rooted in the preverbal period of infant development. Context-mediated cerebral deficits may influence learning capacity, hedonic capacity, behavioral rigidity, and many other factors leading ultimately to impaired social competence and increased vulnerability.

Adaptation, Psychological↗
PubMed1997

Genetic testing, life insurance, and adverse selection.

Life insurance is a key element of the UK social structure in terms of family protection and house purchase; it thus needs to be viewed in this broad context, rather than solely as a commercial activity. Insurers have not so far actively requested genetic tests for life insurance, but have insisted on knowing of and being able to act on existing genetic test information. The main reason given for this has been to avoid serious adverse selection; however, this has never been adequately estimated. Review of the different major categories of Mendelian genetic disorders suggests that the scope for adverse selection is extremely limited and that insurers would lose little, and possibly gain more, by foregoing the disclosure and use of this information in relation to life insurance policies of 'normal' size and nature. The likely future use in service of genetic tests based on susceptibility or population screening makes it especially important that the issue is rapidly resolved for Mendelian disorders; so far there is no sign that insurers are willing to achieve this.

Eligibility Determination↗
PubMed2006

Early maturation as a risk factor for aggression and delinquency in adolescent girls: A review.

Early physical maturation has long been considered a risk factor for the development of delinquent girls. The basis of this relationship has not been fully explored or understood. This review summarises the current literature and research on early physical maturation in adolescent females and places it within a developmental perspective. The process of early physical maturation is also placed within a biopsychosocial model so that risk and protective factors arising from the biological, social, family, education and peer environments can be ascertained. A complex model of maturation and environmental-social interaction is constructed and currently supported by research, but it is clear that a great deal of further work is necessary to fully understand this process.

Adolescent↗
PubMed1992

Clandestine migrant workers in Japan.

The author assesses the problem of illegal labor migration to Japan. "Labor policies, regulations, types of immigration violations, and the role of the recruitment industry are described. Most of the estimated 200,000 illegal workers are employed in small and medium sized enterprises, especially construction and manufacturing, which pay them wages well below the normal rate. A key issue is the infringement of human rights of these illegal workers, who lack the protection of labor laws and the social security system."

Asia↗
PubMed2005

Family connections: a program for preventing child neglect.

Family Connections was a demonstration program specifically designed to prevent child neglect. This article describes the development of prevention strategies and the assessment of outcomes for families who received two versions of the intervention. The sample included 154 families (473 children) in a poor, urban neighborhood who met risk criteria for child neglect and who were randomly assigned to receive either a 3- or 9-month intervention. Self-report and observational data were analyzed using analyses of variance (ANOVA) with repeated measures. Results for the entire sample indicated positive changes in protective factors (parenting attitudes, parenting competence, social support); diminished risk factors (parental depressive symptoms, parenting stress, life stress); and improved child safety (physical and psychological care of children) and behavior (decreased externalizing and internalizing behavior). Results further reflected no advantage of the 9-month intervention for improving parenting adequacy. Further testing of the intervention with other target populations is being conducted.

Child↗