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PubMed1991

The effect of neuromuscular diseases on the development of dental and occlusal characteristics.

Fourteen patients suffering from primary muscular disease (myopathies), including seven with Duchenne's muscular dystrophy, were compared to 11 patients whose neuromuscular disorders were of neuropathic origin. Mesioclusion was observed only in the group with Duchenne's muscular dystrophy. Posterior crossbite, anterior open bite, mouth breathing, and large tongue were also more prevalent in the group with myopathies, especially the Duchenne's patients, than they were in the group with neurogenic disorders. The Duchenne's patients exhibited a statistically significant delay in dental emergence, unlike the patients with other myopathies and those with neurogenic disorders. Dentition and occlusion may be more affected in patients with myopathies, especially Duchenne's muscular dystrophy, than they are in patients with neurogenic disorders.

Adolescent↗
PubMed1994

Class II: a comparison of activator and activator headgear combination appliances.

The purpose of this study was to evaluate skeletal and dental effects of activator and activator high-pull headgear combination appliances on growing patients with Class II, division 1 malocclusion. The material consisted of pre- and post-treatment cephalograms of 17 boys and 20 girls. Seventeen patients (eight male and nine female) were treated with an activator, the remaining 20 (9 male and 11 female) were treated with an activator high-pull headgear combination (AHGC) appliance. Changes due to treatment were compared with a group of 19 (nine male and ten female) untreated children. ANB angle was significantly reduced and mandibular growth development was favourable in both treatment groups. The AHGC appliance was more effective in the reduction of the maxillary prognathism. An increase of the anterior facial height and clockwise rotation of the occlusal plane was observed in the patients treated with activator appliance. The cant of the mandibular plane remained stable during both treatment periods. On the other hand, the forward displacement of the upper first molars was reduced significantly and the axial inclination of the lower incisors was controlled much better with the AHGC appliance.

Activator Appliances↗
PubMed1994

[Orthopedic aspects of orthodontic treatment of patients with labio-palatine clefts].

Cleft lip and palate patients often show a distorted facial growth which can be orthodontically treated by means of "growth guidance". The treatment can be applied during three different phases of the dental development. First phase is immediately after birth where the growth of the alveolar segments are aligned together in order to facilitate the closure of lip and palate. Subsequently, a protraction of the upper jaw is carried out during the first transitional stage; As a result of this, the permanent incisors can erupt in a good sagittal relation. Finally, a transversal expansion of the upper jaw can be applied which is mostly done before alveolar bone grafting. The timing of the grafting procedure depends on the eruption of the upper permanent canine at the cleft side.

Child↗
PubMed1987

The role of function in the development of human craniofacial form--a perspective.

As an anatomical region the head combines great diversity of function with close integration of structure. Consequently no structural component has autonomy of form. There is a sequence of maturation of functions and their related structural components, and in this sequence the nervous system and its supportive structures mature first. The nasal airway matures next in response to increasing body mass, and the masticatory system constitutes the last major functional system to reach maturity. The later the maturation of the function, the greater is the requirement for its related morphology to adapt to preceding skeletal templates. These matters of developmental sequence, and extrinsic as well as intrinsic craniofacial functions, are paramount considerations in interpreting the form of any component of head anatomy.

Face↗
PubMed1986

The morphology of the potential Class III skeletal pattern in the growing child.

The aim of the present article was to identify morphologic characteristics in the craniofacial skeleton of the 11-year-old child that could indicate potential development of a Class III skeletal pattern. A radiographic material consisting of 24 children (13 girls, 11 boys) at an average age of 11 years 0 months, who in adulthood demonstrated a Class III skeletal pattern, was compared with a control group of 33 children (16 boys, 17 girls, average age 11 years 6 months) chosen retrospectively on the basis of Class I occlusion. The analysis was performed by means of both linear and angular variables and results are reported both as group means and individual analyses. No one morphologic trait indicative of potential Class III development could be isolated because the study clearly demonstrated the existence of different skeletal combinations. The development of the maxilla, both in size and position, was clearly demonstrated by the linear analysis to be an etiologic factor in Class III development. However, maxillary retrognathism was usually masked in the angular analysis because a reduction in length of the anterior base with subsequent effect on the position of point nasion was often seen in these cases. Mandibular prognathism was a frequent observation, although a true macrognathia was uncommon. In the majority of cases, mandibular prognathism was the result of an increase in the ratio between mandibular length and dorsal position of the glenoid fossa (articulare). The relative merits of angular and linear analyses are discussed in relation to the results presented.

Cephalometry↗
PubMed1976

Dental and craniofacial development in the normal and growth-retarded human fetus.

Craniofacial and dental development were examined in 32 human fetuses, 22--42 weeks of gestational age, nine of which were classified as light-for-dates (LFD). Statistically significant differences were detected between the LFD and the normal group with respect to upper and lower jaw size and cranial base length but not in the case of neurocranial length, orbital height or deciduous molar crown size. The structures which are least affected by intrauterine growth retardation are those whose growth rate is normally either low throughout the second half of gestation or falls substantially during the 10 weeks prior to term.

Body Weight↗
PubMed1975

Development of the palatal arch in relation to unilateral cleft lip and palate surgery: a comparison of the effects of different surgical approaches.

Our cases are too small in number to conclude which kind of surgical method retards the maxilla development. But we can say that a maldevelopment of the maxilla may be expected to occur in the case of any surgery performed. In the cleft lip only patients, Millard's method and our method show a better effect than the other methods from the point of view of the retardation of the mid-third of the face. In the group of unilateral cleft lip and palate patients our method may be the best on this point. At the end, we would like to present our typical cases with figures (Figures 4 and 5).

Child↗
PubMed1980

[Tongue function in the rehabilitation of speech disorders, faulty breathing habits and deglutition disorders].

The tongue is as an organ of speech and articulation not as indispensable as the soft palate. The recovery of speech after extirpation of the tongue is usually satisfactory, and the intelligibility of patients with microglossia compares favourably with the speech of an untreated cleft palate patient. Hypernasality and nasal escape of air are typical also for the congenital short palate (in the absence of a cleft); syndromes with a congenital short palate are often misdiagnosed as suprabulbar paralysis. The function and involuntary usage of the tongue e.g. in swallowing, influence the growth and development of the surrounding bony structures and the teeth. A frontal open bite due to the tongue thrust habit is a popular example. A case if made for the notion that the mouth-breathing habit has grave consequences such as nasal obstruction, adenoids and glue ears. Mouth breathing should not be looked upon as a trivial accessory phenomenon, but as a behaviour that needs systematic reeducation treatment. Rehabilitative procedures are pointed out for patients with respiratory problems due to two-sides laryngeal nerve paralysis and patients with swallowing problems after partial extirpation of the base of the tongue.

Adult↗
PubMed1997

Growth in the external cranial base evaluated on human dry skulls, using nerve canal openings as references.

The purpose of this investigation was to measure on human dry skulls the postnatal widening and lengthening of the external cranial base, including the hard palate, using nerve canal openings as references. Forty-five Indian dry skulls were examined, 36 from children and 9 from adults. The age evaluation was made on the basis of dental development. The dimensions of the external cranial base were determined by direct measurements on the skulls and by measurements from photographs of the skulls. The study showed that growth in width of the external cranial base followed two distinct patterns. The two regions represent different embryologic developmental fields. The study points out that different growth patterns in these fields ought to be taken into account in future investigations of normal and pathologic craniofacial growth.

Adolescent↗
PubMedDate not supplied

[Role of prolonged sucking in the development of dento-skeletal changes in the face. Review of the literature].

Thumbsucking is the earliest and most common habit in children, affecting almost the 45% of young population in the world, from birth through adolescence. Infantile digital sucking and other non-nutritive sucking habits have been significantly correlated with malocclusion in both primary and permanent dentitions. The severity of malocclusions correlated with such habits depends on the frequency, the duration, the intensity and the position of the thumb in the mouth. Prolonged fingersucking may cause an anterior open bite, diastema, proclination and protrusion of maxillary incisors, increased overjet and overbite, retrusive position of mandible, posterior cross-bite. Self correction of malocclusions may occur if the habit is discontinued before 4 y.o.

Age Factors↗
PubMed1984

Lip pressure changes following lip repair in infants with unilateral clefts of the lip and palate.

The present study was designed to quantitatively assess lip pressure changes following cleft lip repair in infants with unilateral cleft lip, alveolus, and palate. Lip pressure measurements were taken using an electronic transducer system developed especially for this study. Lip pressure was monitored from 3 months (preoperatively) through 2 years of age in cleft and normal control children. Findings from the present study confirm the hypothesis that lip repair in infants with unilateral cleft lip and palate significantly increases lip pressure and that increased lip pressure remains significantly higher than in normal control children for the 2-year duration of the study. Thus increased lip pressure when the palate is unrepaired has to be considered as a factor modulating subsequent craniofacial growth.

Child, Preschool↗
PubMed1998

Postural disorders and dentofacial morphology.

Although the history of opinions regarding poor posture as an etiologic factor for deviant dentofacial development and malocclusions is old, very few controlled studies on this topic have been done. Most of the articles are anecdotal or describe subjective clinical impressions. Some studies do present valid material, but unfortunately they often do not provide enough information about the methods for postural recording. Based on selected studies, this review concludes that there is plausible evidence for an increased prevalence of Angle Class II malocclusions associated with hyperlordosis of the cervical spine and an increased risk of lateral crossbite in children affected by scoliosis and torticollis. Also, documentation of associations between anterior crowding and head posture seem convincing.

Face↗
PubMed2004

Three-dimensional changes in the condyle during development of an asymmetrical mandible in a rat: a microcomputed tomography study.

A rapidly growing postnatal animal model was used to study changes in the calcified tissue of the mandibular condyle during altered muscle function. A maxillary occlusal splint was designed to shift the mandible laterally (left) during closure. Groups of 5 Wistar rats were killed at 5, 9, 15, 21, 30, and 40 weeks (n = 30), with an equal number of controls. The experimental animals developed shorter, asymmetrical mandibles compared with the control animals. The left condyle became larger and thicker than the right condyle. Microcomputed tomography assessment of the left and right condylar trabecular bone indicated that both had less bone volume than the control condyle. The right masseter muscle significantly lost fiber size and type IIA oxidative fibers, suggesting that the right masseter muscle was used with less tension development. In contrast, the left masseter maintained its fiber size and was similar to the control masseter fiber diameters. Comparison in the sequence of changes indicated that the morphologic changes occurred first in the ramus (age, 5 weeks), before the corpus (age, 15 weeks), and before changes in masseter fiber size and composition (age, 9 weeks). This study showed that both the mandible and the condyle modified their shape and size, as well as the trabecular bone of the condyle, during shifting of the mandible to one side as it closed.

Animals↗
PubMed1997

Catch-up growth induced by growth hormone in the craniofacial skeleton of the Snell strain of the hypopituitary dwarf mouse.

Immature Snell strain dwarf mice were treated with human growth hormone for 20 and 40 days, between the ages of 22 and 41 days and 22 and 61 days, respectively. Mature dwarfs were similarly treated for 20 and 40 days between the ages of 62 and 81 days and 62 and 101 days, respectively. These groups of treated mice were compared with untreated dwarfs and normal mice reared under the same conditions. The catch-up growth effected by human growth hormone on the craniofacial and somatic development of the Snell strain dwarf mouse at both immature and mature ages was considerable, overall being approximately 14 per cent. Neurocranial parameters tended toward the values of normal mice achieving 89-98 per cent of normal growth. Viscerocranial parameters showed greater catch-up, from a lower start point, reaching 81-93 per cent of the control. This catch-up in mature mice (aged 82-102 days) was at a time when any substantial growth in either dwarf or normal mice has usually ceased.

Age Factors↗
PubMed1988

1987 Kreshover lecture. Gene regulation in the development of oral tissues.

The regulatory processes associated with tooth formation are being investigated by the identification of when, where, and how cell adhesion molecules (CAMs), substrate adhesion molecules (SAMs), dentin phosphoprotein, enamel gene products, and intermediate cementum products are expressed during sequential developmental stages of morphogenesis, cytodifferentiation, dentin, enamel and cementum extracellular matrix (ECM) formation, and biomineralization. Instructive and permissive signaling is required for both morphogenesis and cytodifferentiation based upon in vitro organotypic culture studies in serumless, chemically-defined medium. Intrinsic developmental instructions, independent of exogenous growth factors, mediate tooth morphogenesis from the initiation of the dental lamina through crown and initial root development. Recent progress using recombinant DNA methods has advanced descriptions of several dental structural genes. The complete nucleic acid sequence for mouse amelogenin has been defined. This sequence is located on the mouse X chromosome and on the human X and Y chromosomes. This discussion summarizes recent results using experimental embryology, recombinant DNA technology, and immunocytology in the context of instructive epithelial-mesenchymal interactions associated with epithelial differentiation into ameloblasts, ectomesenchyme differentiation into odontoblasts, and dentin and enamel ECM biomineralization. The tooth organ provides opportunities at several levels of biological organization to investigate cellular, molecular, and developmental processes.

Animals↗
PubMed1983

Craniofacial growth and size patterns during postnatal development.

Patterns of craniofacial growth and size relationships are described for a mixed longitudinal sample of 26 males and 25 females, followed serially from four years of age through adult status. The seven dimensions examined, derived from 663 lateral cephalograms, show differential patterns of negative allometric growth relative to statural increase. Relative growth is greatest for mandibular traits, followed by upper facial and neurocranial traits, respectively. Males exhibit greater relative growth than females. Craniofacial variation residual to allometry follows three independent patterns of association defined by principal component analysis. The components are age and sex independent, suggesting that after proportional changes related to absolute size or scale are controlled for, anterior facial, cranial height, and masticatory associations follow separate but proportionate patterns during growth.

Adolescent↗
PubMed2007

Dentoskeletal effects and "effective" temporomandibular joint, maxilla and chin changes in good and bad responders to van Beek activator treatment.

OBJECTIVE: To assess possible differences in dentoskeletal effects and "effective" temporomandibular joint, maxilla, and chin changes between good and bad responders to van Beek activator treatment. MATERIALS AND METHODS: The subject material consisted of 20 consecutive normodivergent male Class II division 1 patients treated with a van Beek activator. Because of insufficient cooperation, four patients were excluded. Lateral head films were taken 6 months before treatment, at start of treatment, and after 12 months of treatment. The patients were placed into a good responder group (successful, n = 8) and a bad responder group (unsuccessful, n = 8). An overjet reduction > or =4 mm was considered successful. RESULTS: During the van Beek treatment period, the good responders showed a significantly larger improvement in overjet and molar relationship than did the bad responders. The good responders exhibited a significant posterior development of condylion, less anterior mandibular autorotation, retrusion of upper incisors, protrusion of lower incisors, distalization of maxillary molars, and a mesial movement of mandibular molars. No significant dental movements were seen in the bad responders. CONCLUSIONS: Although van Beek activator treatment affected the direction of condylar growth, as well as the direction of maxilla and chin changes, it can be concluded that skeletal changes did not contribute to the Class II correction. Instead, overjet reduction during van Beek activator treatment was found to be due to a favorable dental reaction.

Activator Appliances↗
PubMed1997

[Early functional surgery as a component of interceptive treatment of developing dysmorphosis in adolescents].

A discordance in the shape and relation between dental arches may be corrected by functional orthopaedics. Discovered in the adolescence, the dysgnathia has yet run its course and it remains just a bit of growth power, this situation justifies to recourse to interceptive surgery, meant for facilitation of oral reeducation and thus harmonisation of residual facial growth. This "functional surgery" is composed of tongue myoplasty, functional genioplasty and the early corrective orthopaedic surgery which is defined by its association with immediate reeducation. It is characterized by its benignity and stability of its results if occlusal and functional surroundings are equilibrated. Moreover, its profits by residual growth power which became well guided, and assures improvement of immediate postoperative results, if needed.

Adolescent↗