Intrauterine intussusception due to Meckel's diverticulum as a cause of ileal atresia: analysis of 2 cases.
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The examination and treatment of 22 children at the age of from 2 to 14 years after surgical correction of fistulous forms of atresia of the anus and rectum was carried out. In all the patients, besides of general clinical investigations, the special studies of the large intestine with the use of roentgenologic and functional methods were performed. A scale-table for assessment of a degree of anal incompetence have been developed, criteria for choice of rational tactics for rehabilitation of the patients established.
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Most cases of isolated nonduodenal bowel atresia are thought to be due to ischemic events from hypotension, vascular accident, volvulus, intussusception and cocaine. We present a case of isolated ileal atresia suggested using results of prenatal sonography which showed multiple markedly dilated fluid-filled intestinal loops with changeable shapes and positions secondary to active peristalsis. Postnatal oral contrast radiography demonstrated obstruction located at the ileal level. Exploratory laparotomy confirmed isolated ileal atresia. Primary end-to-end anastomosis was done. The infant endured the procedure well. Cases with multiple intestinal atresia always have fatal prognosis, even after surgery. Cases of isolated intestinal atresia usually have better prognosis and deserve more attention. Early diagnosis and early intervention are both important for good outcomes.
PURPOSE: The purpose of this report is to investigate changes in the myenteric plexus associated with the dilated proximal segment of jejunoileal atresia (JA). Two-dimensional morphologic changes in the myenteric nerve plexuses were investigated using whole-mount preparation. METHODS: Proximal (P) and distal (D) intestinal segments from 7 cases with JA and control (C) segments from 5 postmortem neonates were investigated. The circumference of the jejunoileal segments was measured after fixation. Antibodies for protein gene product 9.5 and neurofilament protein were used in whole-mount preparation. The sizes of neural networks were calculated by measuring the longest circular distance in a neural network (x) and the longest longitudinal distance (y), and the width of the internodal strands (i) with a videomicrometer. RESULTS: Median circumference of the segments was 8.5 in P, 2.0 in D, and 2.0 cm in C. The neural networks in P were expanded longitudinally as well as circularly (x = 817.10 microm, y = 561.26, i = 31.04: median) while comparing them to those in D (x = 431.40 microm y = 288.07, i = 26.05) or C (x = 285.03 microm y = 372.20, c = 1113.57, i = 32.39). The nerve plexus was less expanded than the intestinal wall. CONCLUSIONS: Proximal intestinal segments showed a restructuring that resulted in mild hypoplasia of the enteric nerve plexuses in the proximal segments. The less expansion of the myenteric nerve plexus seen in the proximal bowel in infants with JA suggests a histologic basis for the efficacy of tapering or plication of the dilated bowel.
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