Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Hypericum”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,279 records · Page 71Linked to original sources
PubMed2002

[Herbal preparations have both effects and side effects. Widespread usage dictates knowledge among physicians].

The article gives a clinically oriented overview of the efficacy and safety of Ginkgo biloba, St. John's wort, ginseng, Echinacea, saw palmetto and kava based on American experiences. Clinical data support the efficacy for some of these drugs. None of them is free of adverse effects. Generally speaking, trials of herbal medicinal products have been too few, too small and too short. The lack of long-term studies is especially unfortunate since many of the drugs are used for a long time. The difference between American and Swedish legislation on herbal medicine products is described.

Echinacea↗
PubMed2003

Taking St John's wort during pregnancy.

QUESTION: A 23-year-old patient of mine has been taking St John's wort for postpartum depression for about 2 years. She is now planning her second pregnancy. Is she or her fetus at risk if she continues to take the herbal therapy? ANSWER: Despite the widespread availability and use of St John's wort and extensive research on the herb, there are almost no data on reproductive safety. At this stage, therefore, St John's wort cannot be recommended as safe therapy during pregnancy.

Adult↗
PubMed2002

[Chemical constituents of Hyperricum monogynum].

OBJECTIVE: To investigate the chemical constituents from the aerial parts of Hyperricum monogynum. METHOD: Compounds were isolated by various column chromatography and identified by spectral analysis. RESULT: Ten compounds were isolated and identified as quercetin, quercitrin, hyperoside, rutin, (-)-epicatechin, 3,5-dihydroxy-1-methoxy-xanthone, 3,4-O-isopropylidenyl shikimic acid, shikimic acid, daucosterol, and oleanoic acid. CONCLUSION: All compounds were isolated from this plant for the first time.

Hypericum↗
PubMed2003

Depressive disorders.

Explore the source record for details and available documents.

Antidepressive Agents, Second-Generation↗
PubMed1960

St. John's wort.

Explore the source record for details and available documents.

Asteraceae↗
PubMed2003

Analysis of the hypericin and pseudohypericin content of commercially available St John's Wort preparations.

CONTEXT: The use of herbal medications and supplements has been growing worldwide with over four billion dollars a year spent on alternative medicines in the United States. St John's wort herbal preparations are generally standardized to "total hypericins" as a means of illustrating a degree of quality control to the consumer. This standardization has been based on a nonspecific method that overestimates and sums the two major naphthodianthrone compounds (hypericin and pseudohypericin) that are found in these products. OBJECTIVE: To use a more specific and sensitive method to accurately determine the total hypericin content (sum of hypericin and pseudohypericin) in commercially available St John's wort herbal preparations. DESIGN: The current standard method for determining the naphthodianthrone content is a spectrophotometric method specified in the United States Pharmacopeia. Compounds other than hypericin and pseudohypericin can contribute falsely to the naphthodianthrone concentration, reducing this methods specificity. SETTING: Fifty-four commercially available St John's wort products were purchased in Canada and the United States. MAIN OUTCOME MEASURES: A specific and sensitive liquid chromatographic method with fluorescent detection was used to specifically quantify the hypericin and pseudohypericin content in commercially purchased St John's wort products. RESULTS: Analysis revealed large variations in total naphthodianthrone content, with the percentage of label claim varying from 0% to 108.62% for capsules, and from 31.34% to 80.18% for tablets. The content of tinctures varied from zero to 118.58 microg/ml. Only two products were observed to have a total naphthodianthrone concentrations within 10% of their label claim. CONCLUSIONS: When the active or marker compounds in an herbal or alternative medicine have been identified, standardization is an important step to ensure consistency from batch to batch. However, consistency is not apparent between brands and most products have inaccurate label claims. On average, most labels overestimate the hypericin and pseudohypericin content by a factor of almost two.

Anthracenes↗
PubMed2003

[Identification of Aaron's beard with clustering analysis by attenuation reflection-Fourier transform infrared spectrometry].

OBJECTIVE: To establish a new method to discriminate Aaron's beard by Fourier transformation infrared spectrometry. METHODS: Attenuation Reflection-Fourier transformation infrared spectrometry with clustering analysis was used to the identification of Aaron's beard. RESULTS: There were obvious differences in Aaron's beard. The results are consistent with that of morphologic study. CONCLUSION: This method is rapid, simple and economical, and can be used to the quality control.

Cluster Analysis↗
PubMed2003

[Diagnosis and treatment of depressive disorders in the doctor's office].

Depression is underdiagnosed and undertreated though its high prevalence and life-threatening character. Once identified, depression can be treated successfully with antidepressants, cognitive behavior therapy/interpersonal psychotherapy or a combination of both. Regarding selection of a particular antidepressant, newer, selective drugs are preferred due to better tolerability and low toxicity.

Aged↗