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Use of three-dimensional computerized tomography reconstruction in complex facial trauma.

Technological advances in computerized tomography (CT) have reduced data acquisition and reconstruction times so that three-dimensional (3D) CT images of maxillofacial injuries may be economically and quickly generated. 3DCT was judged superior to multiplanar two-dimensional CT in demonstrating the spatial relationships of fracture fragments in complex mandibular and midfacial trauma. Although 3DCT failed to demonstrate soft-tissue injuries well, the surgeon's improved appreciation of the disrupted bony architecture facilitated preoperative planning. 3DCT facilitates the evaluation of complex mandibular and midfacial fractures.

Facial Bones↗

[Myofunctional disorders of the orofacial region in childhood. Clinical aspects--etiology--therapy].

The differential diagnosis of myofunctional, articulational and specific ENT-disorders is a phoniatric domain. The symptoms of orofacial dysfunctions are presented and aetiological factors of myofunctional disorders of the orofacial region are discussed for children. In many cases the surgery of ENT-disorders (e.g. adenotomy, tonsillectomy, frenulotomy) makes favorable conditions for logopedic oriented myofunctional therapies according to the age.

Child↗

[Fat suppression in contrast-enhanced MRT of the base of the skull and of the head-neck area: its clinical value].

167 patients with abnormalities at the skull base and at the cervical-skull junction were examined by MRT in order to compare a FATSAT technique with T1- and T2-weighted SE sequences before and after intravenous injection of 0.1 mmol Gd-DTPA/kg KG. The diagnostic information from corresponding FATSAT and T1-SE sequences was correlated with the histopathological findings. In 10.7% of patients fat suppression was inadequate and in a further 11.3% of patients chemical shift artifacts limited the diagnostic value. The number of detectable lesions was not increased by the use of FATSAT sequences but visualisation of soft tissue lesions was improved, adding to the diagnostic value under specific conditions. Evaluating by the Friedman and Wilcoxon test showed that the postcontrast FATSAT sequences were markedly superior (p < 0.01) in delineating and contrasting the lesions. The additional use of contrast enhanced FATSAT sequences resulted in improved diagnosis of lesions at the skull base and the facial skeleton.

Adipose Tissue↗

[Conventional x-ray study and computed tomography in the diagnosis of orbital fractures].

37 cases of skull fractures with involvement of the orbit were reviewed retrospectively. The value of plain films, tomography and computed tomography was analysed. Combined use of 28 degrees Caldwell and water views revealed 96% of all orbital floor fractures. Orbital emphysema in facial bone fractures nearly almost (in 14 of 15 cases) indicated involvement of the medial orbital wall. CT--performed on a biplane basis--showed best diagnostic accuracy in evaluating orbital fractures. Axial CT scans revealed only 70% of all orbital floor fractures. Because of that coronal scans are especially necessary for evaluating the orbital floor and the orbital roof. CT is necessary for evaluating the medial orbital wall since conventional radiology only shows 15% of all medial orbital wall fractures.

Adolescent↗

The effects of clinical data on radiological diagnostic performance in middle-face trauma.

To determine the effect of clinical information on the radiological diagnostic performance in middle-face injury, the medical records and radiographs of 618 patients with middle-face injury were reviewed. The information value of clinical data given in each x-ray requisition was evaluated. The radiological diagnoses were compared with the final clinical diagnoses both retrospectively and prospectively (with and without clinical data). Knowledge of clinical data with statistical significance changed the reader's decision threshold towards improved sensitivity but poorer specificity. Clinical data did not improve the radiologists' performance. Clinical data may be helpful in diagnostic tasks rather by increasing the sensitivity than the specificity.

Evaluation Studies as Topic↗

Frontobasal approach for trauma and tumor.

The potential for remediation of a host of varied disease processes afflicting the skull base has been increasingly realized over the past two decades. Advances in medical technology, the development of new approaches, and most importantly the close cooperation of the head and neck surgeon and the neurological surgeon have made this possible. Surgeons are attempting to diminish the injury to normal un-involved structures while at the same time maximizing exposure and enabling rectification of the disease or disorder. This is especially pertinent in a number of frontobasal approaches used in anterior craniofacial surgery. The osteoplastic flap approach to the posterior wall of the frontal sinus to repair small cerebrospinal fluid leaks and manage posterior wall fractures saves the patient a larger anterior craniotomy and brain retraction. Cranialization of the frontal sinus in comminuted through-and-through fractures allows for removal of devitalized brain, dural repair, and safe management of the frontal sinus. The lateral rhinotomy medial maxillectomy-ethmosphenoidectomy approach coupled with either an osteoplastic flap of the frontal sinus or a low limited craniotomy is an excellent approach for resection of tumors encroaching on the anterior skull base. Even malignancies of this region can be completely excised with adequate margins, yet produce minimal to no facial aesthetic distortion. Moreover, larger tumors requiring a more extensive lip-splitting incision and total maxillectomy with orbital exenteration can often anticipate minimal deformity, especially with good prosthetic rehabilitation. In the resection of aggressive malignancies, techniques of ocular preservation and facial bone sparing have been developed with encouraging cosmetic results.

Cranial Sinuses↗

A systematic review of Swedish research in orthodontics during the past decade.

The aims of this systematic review were to identify the study designs and topics of Swedish orthodontic articles, to elucidate their international position, and to verify in which scientific journals the articles had been published in the past decade. A search of the Medline database for papers published between 1992 and 2002 was made using the Medical Search Heading terms 'orthodontics', 'malocclusion', 'cephalometry', and 'facial bones and growth'. Two independent reviewers selected the articles of Swedish origin and categorized each article according to research design and principal topic. Overall, 15,571 articles in orthodontic research were found, and the Swedish contribution was 1.9% with the majority of these (71.5%) being submitted by universities. Most of the Swedish articles (84.5%) had been published in 10 journals and many high-quality studies with orthodontic interest were published in non-orthodontic journals with higher impact factor scores than the orthodontic journals. Every second study was prospective, and of these, 15 (5.2% of all Swedish articles) were randomized clinical trials (RCTs). It was found that nearly every third study, prospective as well as retrospective, was uncontrolled. The main classification was treatment studies (51.9%), followed by development (18.6%) and diagnostic information (10.7%) studies. Thus, the majority of the articles evaluated therapeutic interventions; however, although the RCT is the preferred study design in evaluation studies, few used this method. In an era focused on evidence-based medicine, studies with an RCT design will be the future challenge for research in the field of orthodontics.

Dental Research↗

The effects of myotonic dystrophy and Duchenne muscular dystrophy on the orofacial muscles and dentofacial morphology.

This article takes a closer view of two of the less rare myopathies, myotonic dystrophy (MyD) and Duchenne muscular dystrophy (DMD). A high prevalence of malocclusions was found among the patients affected by these diseases. The development of the malocclusions in MyD patients seems to be strongly related to the vertical aberration of their craniofacial growth due to the involvement of the masticator, muscles in association with the possibly less affected suprahyoid musculature. Thus, a new situation is established around the teeth transversely. The lowered tongue is not in a position to counterbalance the forces developed during the lowering of the mandible by the stretched facial musculature. This may affect the teeth transversely, decreasing the width of the palate and causing posterior crossbite. The lowered position of the mandible, in combination with the decreased biting forces, may permit an overeruption of the posterior teeth, with increased palatal vault height and development of anterior open bite. The development of the malocclusions in DMD patients also seems to be strongly related to the involvement of the orofacial muscles by the disease. However, the posterior crossbite is not developed owing to the narrow maxillary arch, as is the case in MyD patients. On the contrary, the posterior crossbite in DMD is due to the transversal expansion of the mandibular arch, possibly because of the decreased tonus of the masseter muscle near the molars, in combination with the enlarged hypotonic tongue and the predominance of the less affected orbicularis oris muscle.

Biomechanical Phenomena↗

The effect of muscle repair on postoperative facial skeletal growth in children with bilateral cleft lip and palate.

The effect of orbicularis muscle repair on postoperative facial skeletal growth in bilateral cleft lip and palate patients was studied by analysis of cephalometric radiographs and dental casts. Sixty-two patients operated on between 1961-1989 were selected for the study. They were divided into three groups, group 1a (muscle repair; n = 12), group 1b (failed attempt at muscle repair; n = 5), and group 2 (no attempt at muscle repair; n = 45). Comparison of the morphological measurements among these three groups showed that there was a trend towards crossbite in the muscle repair group, but this difference was not significant. Mechanisms by which muscle repair might influence maxillofacial skeletal growth include the possibility that the area around the nasal septum might be the growth centre. The choice of operative technique in bilateral cleft lip and palate should be important.

Cephalometry↗

Localization and quantitation of eotaxin mRNA in human nasal polyps.

Nasal Polyps (NPs) are the most common mass lesions found in the nose. NPs cause airway obstruction, prevent normal sinus function, and can lead to infection of the eye, facial bones and central nervous system. The predominant cell type inhabiting NPs is the eosinophil, and the chemokine eotaxin is believed to play an important role in NP eosinophilia. The objective of this study was to localize and quantitate expression of eotaxin mRNA in human NPs. Total RNA was isolated from NPs that were collected from 5 patients who had undergone polypectomy. Portions of these polyps were also fixed in formalin, embedded in paraffin, and sectioned onto slides for use in in situ hybridization. Total RNA from one patient was used in a reverse transcriptase polymerase chain reaction using eotaxin specific primers to generate a human eotaxin cDNA. The eotaxin cDNA was cloned and used to generate probes for Northern blot analyses and for use in in situ hybridization (ISH). Eotaxin mRNA was detected by Northern analyses in all patient samples, though the relative expression level in each patient varied. ISH localized the expression of eotaxin mRNA specifically in eosinophils in 2 of the 3 patients in the study for whom the embedded polyp tissue appeared sufficiently well preserved for mRNA localization. Our findings suggest that eosinophilia in NPs is likely a self-amplification process whereby increasing numbers of eosinophils are recruited to enter the polyp as a result of production of eotaxin by eosinophils already within the polyp.

Blotting, Northern↗

An imaging-based computational and experimental study of skull fracture: finite element model development.

The development of a three-dimensional finite element model of the human skull is presented as a part of a novel imaging-based experimental and computational approach to study skull fracture. The rationale for this approach and its potential utility are presented. Mathematical model development, using computed tomography (CT) imaging data as a basis for collecting geometric characteristics of the skull, is given. The model includes anatomical detail of the cranial structure, accurate thickness distributions of the bone and soft tissue components, and density information that can be related to the elastic moduli of the various constituent materials. A procedure for generating the model from CT scan image data is presented. This procedure segments the head into cranial bone, facial, and scalp structures, and the brain.

Humans↗

The effect of professional violin and viola playing on the bony facial structures.

Professional violin and viola playing involves a particular kind of asymmetric face, neck and shoulder muscle activity. The aim of this study was to find out whether players' facial morphology is influenced by this occupational orofacial muscle activity. Lateral and posteroanterior cephalograms and panoramic tomograms of 26 adult professional violin and viola players were evaluated and compared with those of age, sex and dentition matched controls. Significant differences were found between the players and the controls. The players had smaller facial heights, more proclined maxillary incisors and greater mandibular lengths. Thus, intense long-term violin/viola playing has the effect of modifying facial morphology.

Adult↗

Location of the centre of resistance of the upper dentition and the nasomaxillary complex. An experimental study.

The purpose of this study was to investigate the initial displacement of the upper dentition and the nasomaxillary complex as a result of different directions of force application, and to determine the initial centres of resistance for both the upper dentition and the nasomaxillary complex. A macerated human skull with a well-aligned upper arch was used as one experimental model and Araldit 208 as a substitute for the periodontal ligament (PDL). Specifically designed 'antenna-headgear' was developed in an attempt to create different points of force application to simulate high-pull and horizontal traction, and orthopaedic force magnitudes of 8 N were applied to the upper dentition and the nasomaxillary complex. Double exposure holography was used to measure the initial displacement. Reproducibility of the technique was tested and found to be reliable. According to the registered fringe patterns, the force application transmitted by the headgear resulted in complex displacement of facial bones. Pure translation of the maxilla and the upper dentition was observed when the force vector passed by in the area of the key-ridge. No obvious difference was found between the centre of resistance of the upper dentition and the nasomaxillary complex. The location of two different centres of resistance could not be confirmed by measuring initial displacements on this macerated human skull.

Dental Stress Analysis↗

Morphological relationship between the cranial base and dentofacial complex obtained by reconstructive computer tomographic images.

The aims of this study were to investigate the relationships between the cranial base, including the glenoid fossa and maxillofacial morphology, obtained by three-dimensional (3D) computed tomography (CT). The specimens were 45 Skeletal I and Skeletal II dry skulls of modern Japanese males without marked crowding, anterior crossbite, or maxillofacial asymmetry, which had been preserved in the Tokyo University Museum. To examine the differences in the cranial base and maxilla between two groups classified by the median value of N line-A [N defined as a perpendicular line to Frankfort horizontal (FH) through point N, and N line-A as the distance between N and point A]. The specimens with an N-A line less than 1.5 mm were classified as the small group, and those with an N line-A more than 1.5 mm as the large group. Correlation coefficients showed that S-SE was positively related to N-Ba, S-N, S-Ba, and angleFH to S-Ba, and negatively related to SE-N. Ba-X, Ba-Y and Gf-X showed positive correlation with S-Ba and angleFH to S-Ba. For the small group S-SE was longer, angleFH to S-Ba was larger, and Ba-X, Gf-X, A-X, ANS-X, and PNS-X located more posterior and in addition more inferior in ANS-Y. The evidence suggests that S-SE, which is a main component factor of the anterior cranial base, and the antero-posterior position of glenoid fossa, is related to the position of the maxilla. The length and inclination of the posterior cranial base, which is related to Ba, influenced the position of the glenoid fossa.

Adult↗