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Dynamic CT densitometry of hepatic tumors.

Forty-two patients with hepatic tumors were examined by serial computed tomography (CT), using bolus injection of contrast medium. Scanning was at 15, 60, and 120 sec postinjection at a slice level containing the tumor. The densities of the tumor, liver, and aorta were sampled on these and on precontrast CT images. The tumors were divided into four types according to the pattern derived by sequential plotting of the density difference between the tumor and the liver parenchyma. Type I manifested rapid and prolonged high tumor enhancement, in type II the tumor was enhanced rapidly but then quickly became less dense than the liver, in type III there was no significant change over time in the density difference between the tumor and the liver, and type IV showed no, or very little, tumor enhancement. All cavernous hemangiomas belonged to type I while two-thirds of the hepatomas wer type II. There was a good correlation between tumor vascularity on CT and angiography. We suggest that dynamic serial CT scanning technique may be an improvement over the conventional drip-infusion technique in assessing liver tumors.

Absorptiometry, Photon↗

Bone densitometry.

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Absorptiometry, Photon↗

Determination of the radiopacity of intravenous catheters by densitometry.

A general procedure has been developed to quantitatively measure the radiopacity of catheters used for medical purposes. An x-ray film is taken of the test specimen (catheter) under conditions that closely simulate the environment used for taking x-ray films of patients in hospitals or clinics. The x-ray film is scanned using a scanning densitometer such as the Schoeffel SD-3000 spectrodensitometer and the optical density of the catheter image is compared to that obtained for an appropriate aluminum rod control approximately the dimension of the medical device. The basic physical phenomena and operational characteristics involved will be described, and the experimental work will be reviewed.

Absorptiometry, Photon↗

Remodeling of the tibial plateau after knee replacement. CT bone densitometry.

We measured the changes of bone density by computed tomography of the proximal tibia after total knee replacement in 18 patients, 9 with arthrosis and 9 with rheumatoid arthritis. All the patients had good results after 1 and 2 years. There were no significant radiolucencies at the cement-bone interface. At the early postoperative measurements, we found abnormal mediolateral distributions of density, closely related to the preoperative tibiofemoral angle (r = -0.67). This distribution was within normal limits after 3 months in knees with preoperative valgus and after 2 years in knees with preoperative varus. The mean tibial density did not differ between patients with arthrosis and rheumatoid arthritis at the early postoperative examination, but the density in rheumatoid patients decreased by one third during the 2-year period. Although the overall change after knee replacement was loss of density, the preoperatively less loaded condyles had a slight tendency towards increasing density with time, a response that was considerable in some cases.

Absorptiometry, Photon↗

Colles' fracture associated with reduced bone mineral content. Photon densitometry in 74 patients with matched controls.

In a prospective population-based investigation, we measured bone mineral density (BMD) of the forearm using single-photon absorptiometry at both a distal and a more proximal site in 74 Colles'-fracture patients who were compared with controls matched for age, sex, and years after menopause. For both groups there was a marked inverse relationship between age and bone mass. However, over the entire age range, the probands had 11 percent reduced BMD when compared with the controls. Our findings confirm that patients with fracture of the distal forearm have reduced BMD. They constitute an appropriate group for studies aimed at prevention of fracture in the elderly.

Absorptiometry, Photon↗

Bone densitometry. Interpretation and pitfalls.

Dual-energy x-ray absorptiometry (DXA) is the method of choice to measure bone mineral density in elderly patients and others at risk for osteoporosis. Early detection is important because fractures represent an enormous health burden. In this article, the authors discuss the application and interpretation of DXA scans as well as limitations and conditions that can affect results.

Absorptiometry, Photon↗