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[Terminal constipation caused by abdominopelvic asynchrony: analysis of etiological, clinical, manometric data and therapeutic results after rehabilitation by biofeedback].

The aim of this study was to describe the etiological, clinical, rectoanal manometric findings as well as the results of biofeedback therapy in a series of 65 patients (34 males, 31 females, aged between 5 and 77 years) presenting with severe primary constipation due to pelvic abdominal asynchronism. Pelvic abdominal asynchronism was statistically more frequent in males during childhood and in female patients during adult life (p less than 0.005). This study disclosed a high frequency of psychogenic factors in the onset of pelvic abdominal asynchronism (26 p. 100) as well as a high frequency of soiling (46.2 p. 100) in constipated patients. In 36.2 p. 100 of cases, pelvic abdominal asynchronism was the only abnormality. In contrast, in most of the patients, asynchronism was associated with miscellaneous rectoanal disorders: increased anal closure pressure (43.3 p. 100), decreased anal closure pressure (11.8 p. 100), impaired rectal conscious sensitivity (11.7 p. 100), and increased rectal compliance (31 p. 100). This study demonstrated that when high-fiber diet and laxatives fail, biofeedback therapy is a very interesting alternative, providing 80 p. 100 of good results in selected cases. However, we were unable to find any clinical or manometric parameters predictive of results of treatment. Follow-up studies are needed to determine long-term results of biofeedback training.

Adolescent↗

[Value of rectal sensitivity test in chronic childhood constipation].

The rectal sensitivity test evaluates the distension volume for which the initial transient sensation occurs on defecation (conscious rectal sensitivity threshold). The conscious rectal sensitivity threshold (S.S.R.C.) was performed on 10 normal controlled subjects and 103 children with chronic constipation, functional megarectum and normal rectoanal inhibitory reflex. Children were between 5 and 14 years old. S.S.R.C. was increased in children with chronic constipation. Encopresis was proportionally increased with relation to S.S.R.C. increase. A therapeutical protocol was applied in all patients. Fifteen patients are still being treated: 87 obtained a normal function within 8 to 23 months of treatment; in one case the treatment was unsuccessful. The period of treatment was proportional to S.S.R.C. increase. Physiopathological background of a correct management is discussed.

Adolescent↗

[Chronic constipation in childhood--only crux medici or diagnostic pitfall?].

Severe chronic constipation in children is always a burden to the whole family. The typical steps of investigation such conditions are demonstrated. The most common forms of organic causes for chronic constipation are explained by examples; it is important to know them in order to avoid misdiagnosis. Step-by-step-examination is important to find out all organic possibilities.

Adolescent↗

[Diagnostic explorations in constipation].

In 40 patients affected with ano-rectal diseases and presenting with severe constipation, the following tests have been performed: ano-rectal manometry, measurement of the sensitivity to rectal distention, study of intestinal transit time; also in some cases a defecography, double contrast barium enema, biopsies, neurological examination, and blood sugar. In 45% of the cases, the examinations enabled to specify the cause of the constipation and establish corresponding therapeutic indications.

Adult↗

Colonic transit and anorectal manometry in chronic idiopathic constipation.

Twenty-one patients with refractory idiopathic constipation underwent studies of segmental colonic transit of radiopaque markers and anorectal manometry to determine the utility of these tests in planning therapy and in predicting subsequent clinical outcome. Colonic transit studies defined three groups: normal transit (n = 6), colonic inertia (n = 8), and distal slowing (n = 7). Normal transit was universally associated with evidence of psychosocial disturbances. During follow-ups ranging from 23.2 to 26.7 months, six of eight patients with colonic inertia failed to improve compared with only one of seven with distal slowing. Anorectal manometry was useful in excluding abnormalities of anorectal function. Segmental colonic transit of radiopaque markers is a simple and useful test in the evaluation of refractory idiopathic constipation and appears to have both prognostic and therapeutic utility in selected cases.

Adolescent↗

[Anorectal motility in idiopathic constipation. Study of 200 consecutive patients].

The aim of our work was to study anorectal motility and tension of the rectal wall in 200 constipated adult patients. Anorectal manometry was normal in 88 patients (group A), showed abnormal amplitude of the anorectal inhibitory reflex in 33 patients (group B) and hypertonia and ultraslow waves in 70 patients (group C). These anomalies were: a) reproducible in the 20 patients studied twice; b) observed in patients with enterocolitis, thus not specific of constipation; c) associated with an increased frequency of fecal evacuation difficulties. Despite normal values of tension of the rectal wall: a) the threshold of conscious perception of distension was increased in 14 p. 100 of patients; b) a paradoxical relationship between the anorectal inhibitory reflex and rectal tension was observed in group B patients. Our results support the concept of outlet obstruction due to anorectal dysfunction and suggest the possibility of neurologic and or ischemic mechanisms in group B patients.

Adolescent↗

Constipation, bladder instability, urinary tract infection syndrome.

Forty-seven children with recurrent urinary tract infection were noted to have large fecal reservoirs by rectal examination and rectal manometry. Constipation was accompanied in the majority by enuresis and/or encopresis. Urodynamic studies indicated uninhibited bladder contractions. Aggressive treatment of the constipation resulted in cessation of infection in 44 patients, enuresis in 22 of 32 patients and encopresis in 20 of 21 patients and an improvement in bladder function with cessation of all other forms of treatment.

Child↗

[Radiological and instrumental study of the colon in idiopathic constipation].

It has been demonstrated that it is not always possible to attribute to constipation a reduced colonic transit time as being evidenced by radiological studies using radiopaque markers. In fact, in constipated patients with a normal transit time, it was more reasonable to consider a recto-anal disorder as evidenced by defecography and manometry.

Anus Diseases↗

[Constipation in the infant (author's transl)].

The authors studied 102 cases of constipation in children. 76 of them went through a protocol of investigations : clinical, psychological, radiological and manometric. The authors suggest that so-called functional constipation is more often organic than is commonly thought.

Adolescent↗

Traumatic constipation.

In 4 patients, trauma to the lumbosacral area produced abnormalities similar to those seen after resection of the nervi erigentes. Mechanisms of the resulting constipation and fecal incontinence for liquid stools included a prolonged transit time through the entire colon, a low rectal pressure, spasticity of the anal canal, and abnormal anal reflexes. Previous trauma to the lower spine must be considered in the differential diagnosis of chronic constipation.

Adolescent↗

[Relationship between dietary fibers and constipation (author's transl)].

Twenty-two women suffering from constipation were compared with an equal number of controls. Although both groups had similar mean daily total dietary fiber intake (12.4 and 12.7 g respectively) and mean daily cereal fiber intake (3.3 and 3.6 g respectively), the mean mouth-to-anus transit time for food was significantly longer (p less than 0.01) in constipated women (66.8 h) than in controls (48.5 h).

Cellulose↗

[Constipation in the aged. I. Significance, prevalence, causes and treatment].

There is no reason to assume that in old age defecation is different from younger people. Old people who are sound and active often have normal defecation. Their intestinal transit time has been shown to be normal. Nevertheless about fifty percent of the elderly use laxatives. In the very old and in institutions the use is even more frequent. The main cause of this real or supposed constipation is the lack of dietary fibre in the food. In the aged constipation can have dangerous complications, e.g. acute mental confusion, urinary retention, urinary incontinence and fecal impaction. Treatment may include general measurements, the addition of bulk-laxatives to the diet and the prescription of other laxatives. The use of laxatives other than bulk-laxatives may cause many harmful side-effects in the aged. The daily food must contain sufficient dietary fibre. Failing this one can use bran, preparations of psyllium or lactulose syrup.

Aged↗

[The value of anorectal sphincteromyectomy for the diagnosis and treatment of chronic constipation in children].

From January 1974 till the end of 1981, 105 children with chronic constipation not responding to any medical treatment, were submitted to anorectal myomectomy. This operation has both a diagnostic and a therapeutic value; the histological study of the muscle biopsy can confirm or not a Hirschsprung's disease. It is also an ideal treatment in cases of achalasia and idiopathic chronic constipation. If necessary a secondary rectosigmoidectomy can be performed. We did not have any important complication, none of our patients had soiling. Eighty-eight percent of our patients had regular bowel movements after the anorectal myomectomy with a better individual, social and family life.

Adolescent↗

[Meconium constipation in foals].

Meconium constipation is observed in a number of foals during every foaling period. The literature on the clinical picture, methods of treatment and complications, is reviewed in the present paper. In addition, the cases of seventy-five foals are reviewed, in which meconium constipation was suspected and which were submitted to the Internal Disease Department of Large Animals during the period from 1972 to 1982. The clinical picture was found to be due to another disorder in nine cases. Treatment with castor oil and alcohol resulted in discharge of the meconium in fifty-eight cases. Complications occurred in twenty-five foals, fifteen of which died from the effects.

Animals↗

[Distribution and characteristics of chronic constipation among a part of the population of Sofia District].

The authors studied the chronic constipation morbidity among the Sofia district population. It was established that 20.6 per cent of the efficient population is affected. The effect of numerous factors upon the defecation rhythm and constipation incidence is statistically studied. The subjective patient's assessment in the disease diagnosis is underlined. The clinical characteristic of the disease and the present state of the treatment are determined on the base of the data obtained by the inquiry carried out among 3509 inhabitants from the district. The necessity of wider health education upon the problem among the population is stressed upon.

Adult↗

Barium enema in chronic constipation: is it meaningful?

Seventeen pairs of pre- and postoperative barium enemas performed under fixed conditions (same preparation, filling technique, and radiographic factors) were selected from the records of a group of 62 chronically constipated patients who had undergone anorectal myectomy. Measurements at different levels of the large bowel and over-all subjective diagnosis were compared to those made in group of 26 controls. The barium enema did not aid in the diagnosis of constipation or its evolution after surgery.

Adolescent↗

Mechanisms of idiopathic constipation: outlet obstruction.

Anorectal myectomy was performed in 62 patients suffering from symptoms attributed to ineffective colonic motility. Indications for surgery rested on the presence of one or more of the following three criteria: abnormally reduced stool frequency, prolonged transit of radioopaque markers, and abnormal anorectal manometry. One year after myectomy in the 50 patients with less than three stools per week the average number of stools per week increased from 1.2 to 4.2 (P less than 0.001). The remaining 12 patients, who had more than three stools per week, were completely relieved of their symptoms. In all cases with improved symptoms, myectomy acclerated the transit of radioopaque markers through the large bowel. Organic constipation amenable to surgical treatment is more frequent than previously thought. Idiopathic constipation may result from colonic inertia or outlet (anorectal) obstruction.

Adolescent↗

[The role of segmental transit time in the large intestine in the diagnosis of severe constipation].

Segmental small and large bowel transit time of 25 healthy volunteers have been studied, as a control group, by means of radio-opaque markers prepared and administered according to an original method. The same study has been subsequently carried out on 37 patients suffering for chronic non organic constipation. The resulting data, though poorly homogeneous, may however, be plotted in 8 classes; each class groups subjects presenting very similar segmental transit time whose changes are less than 4 hours. The first class gathers the 8.1% of the cases, presenting in increased small bowel transit time; the patients of the second class (5.4%) has resulted affected by "right colon constipation syndrome"; another 5.4% of patients, plotted in the third class have shown a permanence time of the markers in the transverse colon of about 190 hours, while the 10.8% fourth class and the 16.2% fifth class have presented a 97 and 150 hours' one respectively. The patients of the sixth class (21.6%) have shown long lasting permanence of markers in the left colon and in the rectum. The 13.5% of cases, gathered in seventh class, has shown an increased transit time through the whole colon, while at last the eight class (19.0% of patients) has resulted affected by dischezia. The described method has thus revealed useful in the study of bowel segmental transit time from a topographic diagnostic point of view.

Adolescent↗