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[Effect of electromagnetic fields on the living body. II. Changes in alanine and aspartate aminotransferase activities in subcellular fractions of the liver of guinea pigs].

The 50 Hz frequency electric field was applied to guinea pigs at different times of the day. The electric field effects upon the alanine and asparagine aminotransferase in supernatant, mitochondrial and nuclear fractions of guinea pig liver were observed. The highest increase in alanine aminotransferase activity was observed in the mitochondrial fraction, whereas asparagine transferase exhibited the highest activity increase in the supernatant fraction. Those changes may be indicative of adverse effects of electric field upon the liver cell metabolism.

Alanine Transaminase↗

Effects of electromagnetic fields on membrane ion transport of cultured cells.

We have studied the mechanisms of ion transport mediated by Na+/K(+)-pump and Na+,K+,Cl(-)-cotransport pathway of HeLa cells using Rb+ as an analog for K+, and proposed models of binding of ions for the transport pathways. Also, we clarified the relation between ion and water movements in the cells. Based on these findings, we have studied the effects of homogeneous and time-varying magnetic fields on the ion transport activity. The research presented here covers (i) brief explanations of our kinetic studies on the ion transport pathways for promoting understanding of the effects of magnetic fields on the pathways, (ii) our and other reports of the effects of magnetic fields on ion transport systems.

Carrier Proteins↗