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The translator.

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Automation↗

[Data processing in the clinical laboratory (author's transl)].

We will study successively:--the flow of data and biological material into the laboratory and the constitution of the primary message with its attendant areas of possible error generation;--the organization of this data, storage techniques, and methods of information transfer;--common general principles of laboratory organization, constraints to organization inherent in the nature of a given laboratory, and the system of task priority according to the type of laboratory, cases seen and tests required;--perspectives in the development in the handling of results of laboratory tests and diagnostic determinations are briefly discussed.

Computers↗

Microcomputer applications in biomedical research.

Microprocessors and microcomputers are assuming an increasingly important role in clinical and biomedical research. They are applied to the development of new devices for monitoring patients, replacing lost physiologic or sensory function, or performing therapeutic procedures. In research laboratories, microprocessors help to automate instrumentation for measurement and control and to control data collection and analysis functions. Several applications from the National Institutes of Health described by the author illustrate some of these uses.

Computers↗

Modular design of microcomputer-based medical instruments.

A modular design approach is effective for developing compact microcomputer-based medical instruments. Each instrument consists of two modules: a microcomputer instrument module that provides data conversion and computing functions and a characteristic module that does analog signal conditioning and includes all interfaces to the environment. The five instruments summarized here are: (a) a portable, battery-operated arrhythmia monitor for ambulatory patients; (b) a physician's computer for remote telephone communication with the portable monitor; (c) a battery-powered arrhythmia monitor/recorder for the operating room; (d) a portable, battery-operated biofeedback device for speech therapy; and (e) a neuromuscular blockade monitor for the operating room.

Computers↗

Computer-based calibration of the DuPont ACA II.

Desk-top computers equipped with 16K memory and programmed in BASIC can be used to produce calibration calculations for the DuPont ACA II. Entries are made by the operator in accordance with the ACA-supplied calibration format and results may be displayed on a video screen and/or programmed for hard copies to be produced by the use of an interfaced line printer. The operator is provided with the option of computing the Y-intercept from a hand-drawn graph, or allowing the computer to calculate it from the slope. The final printout supplies the averages necessary for plotting the calibration curve, slope and intercept of the line, new intercept, new starting point, and new scale factor. The calibration involved on the ACA II is time-consuming and frequently may produce mathematical errors, both of which are eliminated by the use of the described computer program.

Calibration↗

Laboratory quality control: use of Shewhart charts and ANOVA.

For years industry has used the Shewhart charting system for determining precision and accuracy of industrial products. This method has been adapted to the clinical laboratory, in this project setting, and coupled with analysis of variance (ANOVA). The yield is an in-house quality control (QC) system that graphically shows ongoing precision and accuracy, gives limits of control based on the capabilities of procedures used in three of St. Luke's laboratories, shows within-day and between-day variation, and can be used for evaluation of new methods. The system not only points out problem areas, but enables inexperienced personnel to see when problems exist.

Analysis of Variance↗

The virtual hospital. Providing multimedia decision support tools via the Internet.

Physicians in the clinical setting remain isolated from important sources of medical information. The authors have created a multimedia database known as The Virtual Hospital that improves access to current medical data, which is used to improve patient care decisions. The Virtual Hospital is a digital health sciences library stored on a server (computer) at The University of Iowa and delivered via the Internet to inexpensive personal computers in the workplace. The emerging standard of the World Wide Web is used to provide cross-platform distribution.

Computer Communication Networks↗