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At least 1,261 records · Page 70Linked to original sources
PubMed1995

Ultradian rhythms in performance on tests of specialized cognitive function.

Performance on cognitive tasks cycled at ultradian frequencies for 24 males over a test period of eight hours. The verbal task of written word production cycled at 80 minutes; the spatial task of locating points in space cycled at 96 minutes. Multiple cycles were seen for a perceptual speed task that factor loads on both the verbal and spatial task. Replication of the results for the first 12 and second 12 subjects demonstrated their robustness. The verbal and spatial tasks were chosen to reflect specialized functions of the left and right cerebral hemispheres, respectively. Accordingly, the results are interpreted as evidence that specialized task performances are associated with independent neurochemical systems. In addition, blood samples were taken at task performance to assess cyclicity of hormone levels. Luteinizing hormone had a period of 120 minutes, testosterone and cortisol were inconsistent and none seemed to be related to the cognitive tasks. However when subjects were divided according to a winter or summer testing schedule, the spatial periodicity was absent for the summer group and the verbal periodicity was absent for the winter peak.

Activity Cycles↗
PubMed1997

The development of the "Cantonese receptive vocabulary test' for children aged 2-6 in Hong Kong.

The study aims to develop a Cantonese receptive vocabulary test to assess 2-6-year-old children in Hong Kong. The test consists of 100 test items. Each target item is accompanied by a phonological distractor, a semantic distractor and an unrelated distractor. A sample of 609 normal children from four Maternal and Child Health Centres and nine kindergartens was selected. The results show that there is a significant effect of age on the correct score. ANOVA was performed to look at the age effect on each distractor individually. It was found that the scores of the three distractors decrease in their own patterns as age increases. With strong content validity, strong construct validity and high correlation coefficients in the split-half reliability, this test could be used as a reliable measurement for the Cantonese-speaking population in Hong Kong.

Analysis of Variance↗
PubMed1998

Children's acquired aphasia screening test.

Diagnosis in acquired childhood aphasia (ACA) is a multi-stage process. After the medical condition has stabilised, the diagnostic evaluation requires careful assessment to establish a profile in the differential diagnosis of listening, understanding speaking, and gesture. Children with ACA were traditionally assessed on adapted batteries often used for adults. The Children's Acquired Aphasia Screening Test (CAAST) was specifically designed to evaluate linguistic and non-linguistic function in brain-damaged children aged between 3 and 7 years.

Aphasia↗
PubMedDate not supplied

[Acquirement of the Spanish vocabulary among rural and urban students of the 9th region].

In order to test the assumption that rural children from the Araucanía region at southern Chile start school with significant handicaps in the acquirement of the spanish vocabulary when compared with their urban peers, the Peabody Picture Vocabulary Test (PPVT, spanish version) was used to compare a first group including all those children attending third grade at a public school from a low socio economic level neighborhood of the city of Temuco, Chile (n = 44, age average 9.01 years, s = 0.51) against a second group including all those children attending the same grade at three public schools from the rural areas surrounding the same city (n = 37, age average 9.07 years, s = 0.52). Previously, 19 children aged 3 to 5 years were tested both with the PPVT and with the chilean instrument for the measurement of development at the age group (TEPSI). Both scores show a positive correlation (r = 0.64, p = 0.05). Average scores for the PPVT among rural children were lower than among urban children (64.07, s = 11.36 against 103.05, s = 10.99, p = less than 0.01). In a second stage, 39 children attending 7th grade at the urban school (age average 13.61 years, s = 0.64) and 27 children of the same grade from the rural schools (age average 13.69 years, s = 0.69) were tested with the same instrument.(ABSTRACT TRUNCATED AT 250 WORDS)

Acculturation↗
PubMed2000

Neuropsychological consequences of cerebellar tumour resection in children: cerebellar cognitive affective syndrome in a paediatric population.

Acquired cerebellar lesions in adults have been shown to produce impairments in higher function as exemplified by the cerebellar cognitive affective syndrome. It is not yet known whether similar findings occur in children with acquired cerebellar lesions, and whether developmental factors influence their presentation. In studies to date, survivors of childhood cerebellar tumours who demonstrate long-term deficits in cognitive functions have undergone surgery as well as cranial irradiation or methotrexate treatment. Investigation of the effects of the cerebellar lesion independent of the known deleterious effects of these agents is important for understanding the role of the cerebellum in cognitive and affective development and for informing treatment and rehabilitation strategies. If the cerebellar contribution to cognition and affect is significant, then damage in childhood may influence a wide range of psychological processes, both as an immediate consequence and as these processes fail to develop normally later on. In this study we evaluated neuropsychological data in 19 children who underwent resection of cerebellar tumours but who received neither cranial irradiation nor methotrexate chemotherapy. Impairments were noted in executive function, including planning and sequencing, and in visual-spatial function, expressive language, verbal memory and modulation of affect. These deficits were common and in some cases could be dissociated from motor deficits. Lesions of the vermis in particular were associated with dysregulation of affect. Behavioural deficits were more apparent in older than younger children. These results reveal that clinically relevant neuropsychological changes may occur following cerebellar tumour resection in children. Age at the time of surgery and the site of the cerebellar lesion influence the neurobehavioural outcome. The results of the present study indicate that the cerebellar cognitive affective syndrome is evident in children as well as in adults, and they provide further clinical evidence that the cerebellum is an essential node in the distributed neural circuitry subserving higher-order behaviours.

Adolescent↗
PubMed2004

Brain activation patterns during a verbal fluency test-a functional MRI study in healthy volunteers and patients with schizophrenia.

FMRI was used to study cortical activation patterns in nine healthy male subjects and nine high-functioning male schizophrenia patients during a letter verbal fluency task. Both groups showed similar patterns of activation, however, in controls the activation was primarily in the left broca area, while for schizophrenia patients, it was more bilateral. These data indicate that high-functioning schizophrenia patients show a reduced language lateralization of the frontal cortex compared to healthy controls.

Adult↗
PubMed2002

Sentence completion test in combat veterans with and without PTSD: preliminary findings.

This study used a sentence completion task to assess semantic choice in combat veterans. Twenty-eight combat veterans with (n=14) and without (n=14) posttraumatic stress disorder (PTSD) filled in the final word for 33 incomplete sentences after receiving a combat prime. The veterans with PTSD completed sentences with significantly more trauma-relevant final words than those without PTSD. Findings are interpreted with respect to current language models and information-processing theories of PTSD.

Arousal↗
PubMed2005

[The "Lector"--a testing method to determine verbal educational level].

Assessment of the educational level is important to prevent false neuropsychological diagnostic decisions. In the German-speaking countries some instruments for this assessment already exist, but there are problems involved in the practical application. There still is no reading test, which is a common standard in international neuropsychological test batteries. The lector investigates how subjects read rare German words or foreign words used in German-speaking countries. Words were selected which are pronounced differently from German pronunciation rules. A subject who does not know the word will pronounce it false, i.e., according to the German pronunciation rule. Norms (percentiles), estimation of reliability, and first data about validity were calculated from three samples with a total of 503 subjects. On the basis of the data presented, the Lector Test can be used as a control variable in research with groups as well as in neuropsychological diagnostics.

Aged↗
PubMed1984

Transsexualism and Slater's Selective Vocabulary Test.

It has been shown elsewhere that transsexual males use a vocabulary which differs from that of normal males. This could be demonstrated by Slater's Selective Vocabulary Test. This test was administered to 56 male transsexuals and the 'd' score - a device to eliminate the influence of I.Q. - was calculated. The normal d score for males is zero and the higher the score the greater is the degree of femininity. An attempt was made to find factors which facilitate this abnormal development of the vocabulary in male transsexuals. In order to do this the cases were divided into a group of high and a group of low 'd' scores, and tested for correlations with a number of factors which seemed likely to influence the vocabulary development. No such correlations could be established.

Adolescent↗
PubMed2006

Diathesis-stress and depressed mood among adults with mental retardation.

The impact of diatheses, stress, and their interaction on depressed mood was evaluated to determine the appropriateness of cognitive diathesis-stress models of depression for adults with mental retardation. We also tested hopelessness as a mediator in the prediction of depressed mood to evaluate the hopelessness theory of depression. Seventy-three adults with mental retardation and adequate receptive vocabulary participated in semi-structured interviews. Experiencing life stressors and possessing a negative attributional style, but not their interaction, served as predictors of depressed mood. Similar results were obtained using frequency or impact ratings of life stress. Conditions were not met to test hopelessness as a mediator. Treatment implications for depression among adults with mental retardation are highlighted.

Adult↗
PubMed1983

Drawing objects from memory in aphasia.

The ability of aphasic patients to draw from memory objects with a characteristic shape has been investigated. Their capacity to reproduce the form of real objects was studied by showing them for a short time line drawings of simple objects. When the patient had analysed and recognized the figure, the model was hidden from view and the subject was asked to draw the same object from memory. This Drawing from Memory task was administered to 54 aphasics, 67 patients with right hemisphere lesions, 44 nonaphasic left brain-damaged patients and 23 normal controls. The influence of visuoconstructive disabilities was controlled by administering to the same patients a standard test for constructional apraxia (copying 10 geometrical figures). The severity and clinical form of the aphasia and the presence of semantic-lexical impairment at the receptive level were also examined in the aphasic patients. The following results were obtained. (1) Aphasic patients scored significantly less well than the control groups on the Drawing from Memory task and the intergroup differences became greater when the scores from the test for constructional apraxia were included by an analysis of covariance. (2) No significant correlation was detected between the severity and clinical form of the aphasia and the scores obtained on the Drawing from Memory task. (3) There was a significant correlation between impaired drawing from memory and disruption at the semantic-lexical level of language integration.

Aged↗
PubMed1995

Neuropsychological test performance and prediction of functional capacities among Spanish-speaking and English-speaking patients with dementia.

Neuropsychological measures have been widely used by clinicians to assist them in making judgments regarding a cognitively impaired patient's ability to independently perform important activities of daily living. However, important questions have been raised concerning the degree to which neuropsychological instruments can predict a broad array of specific functional capacities required in the home environment. In the present study, we examined 127 English-speaking and 56 Spanish-speaking patients with Alzheimer's disease (AD) and determined the extent to which various neuropsychological measures and demographic variables were predictive of performance on functional measures administered within the clinical setting. Among English-speaking AD patients, Block Design and Digit-Span of the WAIS-R, as well as tests of language were among the strongest predictors of functional performance. For Spanish-speakers, Block Design, The Mini-Mental State Evaluation (MMSE) and Digit Span had the optimal predictive power. When stepwise regression was conducted on the entire sample of 183 subjects, ethnicity emerged as a statistically significant predictor variable on one of the seven functional tests (writing a check). Despite the predictive power of several of the neuropsychological measures for both groups, most of the variability in objective functional performance could not be explained in our regression models. As a result, it would appear prudent to include functional measures as part of a comprehensive neuropsychological evaluation for dementia.

Journal Article↗
PubMed1993

Relation between mental age and vocabulary development among children with mild mental retardation.

An investigation of the relation between lexical knowledge and mental age (MA) in elementary school-age children with mild mental retardation was conducted. Lexical knowledge was assessed using the Peabody Picture Vocabulary Test-Revised (PPVT-R) and the Boehm Test of Basic Concepts. Items on the PPVT-R focus on labels for objects and events; items on the Boehm focus on relational terms. Mental age was measured via the Columbia Mental Maturity Scale. Results indicated that the relation between lexical knowledge and MA depended upon the nature of the vocabulary test: The correlation between the Boehm and MA was significantly higher than that between the PPVT-R and MA, suggesting that for this population, MA is more strongly related to knowledge of abstract relational terms than to knowledge of labels for objects and events. The latter may be more open to the influence of differential language experience.

Child↗
PubMed1978

Auditory semantic, syntactic, and retention errors made by aphasic subjects on the Token Test.

The Token Test was administered to 25 mild aphasic and 25 matched normal subjects for the purpose of determining the linguistic nature of the auditory verbal comprehension error responses. As was expected, the aphasic subjects obtained significantly poorer scores on the Token Test than did the normal subjects, with minimal overlap between the two groups. In Parts I-IV, the errors were exclusively semantic, and reflected only the amount of required verbal memory. In Part V, the syntactic structures vary, and the aphasic subjects showed a similar pattern of difficulty as did the normal subjects. Syntactic errors were more prevalent than semantic errors in Part V, suggesting that syntactic complexity was the most important factor in verbal comprehension on this part. In comparison to previous research utilizing the Token Test with normal children, the aphasic subjects in the present study generally had high error rates on the same items as did the children.

Adult↗
PubMed1986

Validity of multiple-sentence reading comprehension tests for aphasic adults.

This study assessed the passage dependency of multiple-sentence reading test items from the Boston Diagnostic Aphasia Examination (Goodglass & Kaplan, 1983), the Minnesota Test for Differential Diagnosis of Aphasia (Schuell, 1965), Examining for Aphasia (Eisenson, 1954), the Reading Comprehension Battery for Aphasia (LaPointe & Horner, 1979), and the Western Aphasia Battery (Kertesz, 1982). More than half of the test items from these reading tests were answered correctly by a significantly greater than chance number of both aphasic and non-brain-damaged adults without reading the passages whose comprehension the items purported to test. These results suggest that published tests for assessing aphasic persons' comprehension of multiple-sentence passages do not provide valid estimates of such persons' ability to comprehend information from printed texts.

Aged↗
PubMed1997

Determinants of sentence comprehension in aphasic patients in sentence-picture matching tasks.

The results of two studies of sentence comprehension in aphasic patients using sentence-picture matching tests are presented. In the first study, 52 aphasic patients were tested on 10 sentence types. Analysis of the number of correct responses per sentence type showed effects of syntactic complexity and number of propositions. Factor analysis yielded first factors that accounted for two-thirds of the variance in performance to which all sentence types contributed. Clustering analysis yielded groups of patients whose performances progressively deteriorated and in which performance was more affected by sentence types that were harder for the group overall. These results were very similar to those previously obtained using an enactment task. In the second study, 17 aphasic patients were tested on the same 10 sentence types using both sentence-picture matching and enactment tasks. Correlational analyses showed that performance on the two tests was significantly correlated across both subjects and sentences. The results provide data relevant to the determinants of the complexity of a sentence in auditory comprehension.

Adult↗
PubMed1998

Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD, part XVIII. Consortium to Establish a Registry for Alzheimer's Disease.

OBJECTIVE: To study the relation between cerebral infarction and clinical and neuropsychologic manifestations in patients with autopsy-proven Alzheimer's disease (AD) enrolled in the Consortium to Establish a Registry for Alzheimer's Disease (CERAD). BACKGROUND: Prior studies report that subjects with neuropathologic evidence of AD and concomitant brain infarcts had poorer cognitive function and higher frequency of dementia than those with AD alone. METHODS: Clinical and neuropsychologic manifestations of dementia were studied in 74 subjects with neuropathologic findings of AD alone and 32 with AD and concomitant cerebral infarcts or lacunar lesions. RESULTS: The 32 patients with both AD and vascular lesions were significantly older at time of death (median age, 81 years) than the 74 patients with AD alone (76 years; p = 0.02). At the final follow-up visit, the severity of the dementia was greater in AD patients with vascular lesions (median Clinical Dementia Rating [CDR] = 3) than in those with AD alone (CDR = 2; p = 0.03). Patients with AD and vascular lesions performed significantly worse on verbal fluency, Boston Naming, and Mini-Mental State Examination (MMSE) tests. No differences between the groups were observed, however, in the semiquantitative measures of frequency of neuritic plaques or neurofibrillary tangles. CONCLUSIONS: The clinical-neuropathologic correlations in CERAD patients generally confirm those in prior studies, indicating that the presence of cerebral infarction in patients with AD is associated with greater overall severity of clinical dementia and poorer performance on specific tests of language and cognitive function.

Aged↗
PubMed1996

Long-term consistency in speech/language profiles: II. Behavioral, emotional, and social outcomes.

OBJECTIVE: This study examined the 7-year behavioral, emotional, and social outcome of speech/language-impaired and control children selected from a community sample. METHOD: Speech/language and psychosocial measures were administered to the children at ages 5 and 12.5 years. Using children's age 5 speech/language test results, a cluster analysis was performed to ascertain whether specific linguistic subgroups would emerge. The association between speech/language cluster at age 5 and psychosocial functioning at age 12.5 was examined. RESULTS: Children with receptive and pervasive speech/language problems at age 5 demonstrated greater behavioral disturbance than children without such impairment. Controlling for initial behavioral status, early childhood language profile was still associated with behavioral and social competence ratings, 7 years later. Children without receptive language problems showed superior social adjustment. CONCLUSIONS: Empirically supported speech/language classifications identified as early as age 5 were associated with behavioral disturbance in late childhood. Receptive and pervasive speech/language impairment in early childhood was associated with the greatest risk at follow-up. Early auditory comprehension problems may be a specific risk factor for later aggressive and hyperactive symptoms. These findings identify the need for effective intervention with speech/language-impaired children.

Affective Symptoms↗