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At least 1,261 records · Page 70Linked to original sources
PubMed1980

Incontinentia pigmenti. A four-generation study.

Seven individual members with incontinentia pigmenti are described from a family spanning four generations. The natural history of the cutaneous, ocular, hair, and dental anomalies is described for each involved member. In addition, a previously undescribed ectodermal defect, woolly-hair nevus, appeared in several affected members of this family. Evidence is offered to support the theory that the pattern of inheritance of incontinentia pigmenti is by linkage of the gene on the X chromosome acting as a dominant gene in females and lethal in males.

Abnormalities, Multiple↗
PubMed1995

Lids, lacrimals, and lashes.

The eyelids and lashes serve to protect the globe from foreign bodies and injuries, and the lacrimal system protects the eyes through lubrication of the corneal and conjunctival surfaces. This article discusses trauma, infection, inflammation, anatomic abnormalities, and tumors that may result in serious complications interfering with normal eye function.

Eye Injuries↗
PubMed1994

Acceptance of surgery for trichiasis among rural Malawian women.

We sought to determine the proportion of women with trichiasis who subsequently accepted surgery and to evaluate factors related to acceptance. Women who accepted surgery were more likely to be widows, to be of low socioeconomic status, to live close to a main road, to know another woman who had surgery for trichiasis, and to have trichiasis in both eyes than women who did not accept surgery. Our results suggest that considerable education and encouragement are needed to increase acceptance of surgery for trichiasis.

Eyelashes↗
PubMed1994

[Frequency of occurrence of symptomatic and asymptomatic eyelid mite infestations among inhabitants of Szczecin].

Group of 529 patients, inhabitants of Szczecin, was examined for the presence of Demodex spp. in eyelid hair follicles. The incidence of infestation increased with age. High intensity of infection by Demodex spp.--44%-86%--was noted in age groups: 17-25, 26-34 and over 35 years. In group of subjects 26-34 years and older were noted 46%-80% of symptomatic infestation cases.

Adolescent↗
PubMed1994

Distichiasis-lymphoedema syndrome: a family report.

Distichiasis-lymphoedema syndrome is described in a mother and son. The mother was found to have a double uterus in addition to distichiasis and peripheral oedema. Her son presented with the Pierre Robin sequence which is a rare but previously described feature of the condition.

Abnormalities, Multiple↗
PubMed1994

Normal eyelid crease position in children.

Proportions of the upper lid were determined based on the following measurements in 33 children: lash-line-lid crease (LC), lashline-lower brow (LB), vertical fissure, and horizontal fissure. Age-matched mean measurements (mean LC/LB ratio = 0.33) for 26 white vs 7 black children, and for 16 males vs 17 females were not significantly different. However, the mean ratio in 15 preschool and school-age children was significantly greater than that in 18 infants and toddlers (less than 4 years old) (P < .01). We conclude that the normal eyelid crease position in children is one third up the lashline to the lower brow. However, the normal eyelid crease position in infants and toddlers is slightly less than, and, in older preschool and school-age children, slightly greater than this distance up the lashline. Thus, age may determine the surgical placement of the eyelid crease in children with indistinct creases.

Adolescent↗
PubMed1993

Eyelid imbrication. An unrecognized cause of chronic ocular irritation.

BACKGROUND: Eighteen patients with chronic ocular irritation were examined over a 3-year period. All patients demonstrated papillary conjunctivitis and, occasionally, tarsal ulcers. Six also had floppy eyelid syndrome. Underlying every patient's symptoms was the overriding or imbrication of a lax upper eyelid on an often equally lax lower eyelid, allowing lower eyelid lashes to chronically rub the upper eyelid tarsal conjunctiva. METHODS: Chronic ocular irritation in five patients was managed with ocular lubricants. Two of these patients had floppy eyelid syndrome and required nightime shielding for nocturnal eyelid eversion. Thirteen patients underwent eyelid surgery to correct the overriding upper eyelid. Surgical procedures included full-thickness upper eyelid wedge resection, lateral canthal tendon plication, and lower eyelid horizontal shortening, using a tarsal strip procedure. RESULTS: Follow-up averaged 2.5 years. Symptomatology was adequately controlled in all patients. In addition to the five patients who received medical treatment for their symptoms, two with complicated ocular problems required continued ocular lubrication after surgery. Seven patients were successfully treated with eyelid shortening procedures and lateral canthal tendon plication. The remaining six patients underwent a variety of additional eyelid surgeries. All patients undergoing surgery had complete resolution of eyelid imbrication. CONCLUSIONS: Eyelid imbrication is a previously unrecognized cause of chronic ocular irritation. In this condition, eyelid laxity causes the upper eyelid to override the lower eyelid, allowing the lower eyelid to chronically rub and chafe the upper eyelid tarsal conjunctiva. In some cases, symptoms can be managed medically. More often, surgical intervention is required to correct eyelid laxity and prevent overriding of the upper eyelid.

Aged↗
PubMed1996

[A histopathological study of corneal amyloidosis secondary to trichiasis].

We present a case of secondary corneal amyloidosis whose etiological mechanism was investigated by immunohistochemistry and electron microscopy. A 48-year-old woman had suffered from trichiasis in the right eye for 35 years, and developed secondary corneal amyloidosis, a phenomenon previously described but whose etiological mechanism has not been explained. Slitlamp examination of the cornea revealed a white excrescence with a diameter of 2 mm. The lesion was excised and examined by light and electron microscopy. Large deposits of an amorphous eosinophilic material were observed beneath the atrophic epithelium. Amyloid was detected in these deposits using Congo red stain, polarized light, and electron microscopy. Neither vascularization nor infiltration of inflammatory cells was observed. Immunohistochemical tests for protein AL, protein AA, prealbumin, beta 2-microglobulin and cytokeratin in paraffin sections were all negative. Characteristic findings were observed in the border zone between the basal cells and the deposits. Numerous digitiform cell processes and membrane-bound globular fragments of basal cells were seen in the superficial region of the deposits. The cell membrane of some globules was interrupted and the contents appeared to have been discharged into the stroma. These findings suggest that basal cells of the corneal epithelium provide an amyloid precursor on the stroma.

Amyloidosis↗
PubMed1976

Total lower lid reconstruction: technical details.

The main complications of this type of lower lid reconstruction are lash loss or malposition, entropion of the upper lid, upper lid retraction, undue laxity of the lower lid, and lid margin deformities. These can all be avioded by meticulous attention to surgical details and dressing techniques. I believe that this is the best and simplest method of providing a lid of acceptable function and appearance. The advantages of this type of operation are: (1) The new lower lid is constructed of lid tissue including the tarsus and conjunctiva from the upper lid. (2) The function and appearance of the new lower lid are acceptable with practically no tendency to late retraction. (3) The function and appearance of the upper lid need not be interfered with. (4) No external scars are produced except when a lash transplant is done. This transplant leaves a small, hardly noticeable scar in the lower part of the opposite brow. (5) The technique is relatively simple and well within the realm of any well-trained ophthalmic surgeon. The obvious disadvantages are the surgeon's inability to inspect the eye for two to four months and the inconvenience to the patient of having one eye closed for such a long period of time.

Alopecia↗