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Web-based resources for health care providers and women following pregnancy loss.

Experiencing perinatal loss can leave women and families feeling distressed, overwhelmed, and with many questions, while health care providers often lack time and may not be prepared to provide all the answers. This paper highlights the rationale for use and benefits of the Internet with this population and outlines an effort to review and select reliable Internet resources containing valid and substantial content specific to pregnancy loss. A summary table is included for distribution to women and providers.

Abortion, Spontaneous↗
PubMed2004

Identification of polymorphic tandem repeats by direct comparison of genome sequence from different bacterial strains: a web-based resource.

BACKGROUND: Polymorphic tandem repeat typing is a new generic technology which has been proved to be very efficient for bacterial pathogens such as B. anthracis, M. tuberculosis, P. aeruginosa, L. pneumophila, Y. pestis. The previously developed tandem repeats database takes advantage of the release of genome sequence data for a growing number of bacteria to facilitate the identification of tandem repeats. The development of an assay then requires the evaluation of tandem repeat polymorphism on well-selected sets of isolates. In the case of major human pathogens, such as S. aureus, more than one strain is being sequenced, so that tandem repeats most likely to be polymorphic can now be selected in silico based on genome sequence comparison. RESULTS: In addition to the previously described general Tandem Repeats Database, we have developed a tool to automatically identify tandem repeats of a different length in the genome sequence of two (or more) closely related bacterial strains. Genome comparisons are pre-computed. The results of the comparisons are parsed in a database, which can be conveniently queried over the internet according to criteria of practical value, including repeat unit length, predicted size difference, etc. Comparisons are available for 16 bacterial species, and the orthopox viruses, including the variola virus and three of its close neighbors. CONCLUSIONS: We are presenting an internet-based resource to help develop and perform tandem repeats based bacterial strain typing. The tools accessible at http://minisatellites.u-psud.fr now comprise four parts. The Tandem Repeats Database enables the identification of tandem repeats across entire genomes. The Strain Comparison Page identifies tandem repeats differing between different genome sequences from the same species. The "Blast in the Tandem Repeats Database" facilitates the search for a known tandem repeat and the prediction of amplification product sizes. The "Bacterial Genotyping Page" is a service for strain identification at the subspecies level.

Bacteria↗
PubMed2006

Helping people cope with bereavement: an opportunity for health care providers to link Web-based resources across Minnesota.

The death of a loved one has a profound effect on the surviving spouse or partner, family members, and friends. But the bereaved may not always get the help and support they need. This article reviews the toll that grief takes on individuals and society and highlights the importance of connecting grieving loved ones with resources that can help them. It also suggests a need for health care institutions across the state to share information about their particular resources via the Internet with health care providers and patients.

Adaptation, Psychological↗
PubMed2002

Legionella resources on the world wide web.

Internet resources that focus on Legionella and legionnaires disease are presented. Web sites were selected on the basis of their content and adherence to suggested standards of medical Internet publishing. Free, accessible, English-language Web sites were categorized according to users' needs as follows: (1) those with comprehensive information on Legionella infection (including pathophysiologic characteristics, symptoms, and treatment of legionnaires disease), (2) those with information on outbreaks and epidemiology (including information for travelers), (3) those with information for researchers, (4) those about prevention, and (5) those with information for laypersons.

Humans↗
PubMed2001

[Introduction to Go! Poly, a human genome polymorphism database].

Databases play an important role in the study of genetic polymorphism. To meet the need for more studies of human genome polymorphism by Chinese medical and pharmaceutical community, a gene oriented human genome polymorphism database-Go! Poly was constructed. As a generalized polymorphism database, Go! Poly extracted human gene-linked sequence variations of all common types from various public resources including scientific journals and Web resources such as HGBASE (http://hgbase.cgr.ki.se) and dbSNP (http://www.ncbi.nlm.nih.gov/SNP/). The polymorphism data were then categorized into different gene loci, and the reference sequences given by LocusLink were used as positioning reference. To facilitate the use, a friendly web interface and a text based query strategy were implemented. Users can fetch specific polymorphism data in just three steps: find specific gene locus by simple search, display sequence variation information of a specific gene locus select, and view the final result of a specific variation site. Besides, a web-based submission tool is provided for direct submission, which can make the polymorphism information generated by the Chinese scientific community available from this resource.

China↗
PubMed2003

Profile of on-line anatomy information resources: design and instructional implications.

This study is based on a review of 40 on-line anatomy web resources compiled from sites selected from our own searches as well as sites reviewed and published by an external group (Voiglio et al., 1999, Surg. Radiol. Anat. 21:65-68; Frasca et al., 2000, Surg. Radiol. Anat. 22:107-110). The purpose of our survey was to propose criteria by which anatomy educators could judge the characteristics of the currently available web-based resources for incorporation into the courses they teach. Each site was reviewed and scored based on a survey matrix that included four main categories: 1). site background information, 2). content components, 3). interactivity features, and 4). user interface design components. The average score of the reviewed sites was 3.3 of the total possible score of 10, indicating the limited use of computer-based design features by the majority of sites. We found, however, a number of programs in each of the survey categories that could serve as prototypes for designing future on-line anatomy resources. From the survey we conclude that various design features are less important than the comprehensiveness, depth, and logical organization of content. We suggest that the content should be sufficient for supporting explicitly defined educational objectives, which should target specific end-user populations. The majority of anatomy programs currently accessible on-line fall short of these requirements. There is a need for a coordinated and synergistic effort to generate a comprehensive anatomical information resource that is of sufficient quality and depth to support higher levels of learning beyond the memorization of structure names. Such a resource is a prerequisite for meaningful on-line anatomy education.

Anatomy↗
PubMed2002

Muddy perceptions/dirty water: messages for clearing the visions of the public and the powerful.

Globalism does not usually work when it comes to spreading the word about water! There is no one formula for explaining water issues to the public or to public officials. Sometimes you should go to reporters. Sometimes you should focus on educating editors. Sometimes you concentrate on educating teachers, sometimes the business community, bureaucrats or elected officials. Sometimes your message concentrates on fisheries, sometimes health, sometimes tourism. Often, you will want to emphasize something else--even sales of genetic material that might be dependent on biodiversity. In short, your message must be adapted to the local circumstance. Your methodology will depend on whether you must stimulate immediate action, or whether you have the luxury of pushing a longer-term message. The Web opens many new possibilities. Cost of Web distribution is low. The Web offers a combination of many effective storytelling tools such as audio, video, and animation. Multi-lingual materials are easier to prepare than for film. But at this stage of Web development it may be more efficient to provide material to existing publications' Web sites and to NGOs and official sites, than to establish special stand-alone Web sites. I propose a "resource" Web site for those who have responsibility for water projects. The site would contain articles and explanatory material provided by media organizations, attracted by a modest contest-and-prize system.

Commerce↗