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At least 127 records · Page 7Linked to original sources
PubMed1992

High-performance computing in radiation cancer treatment.

In 1989 a consortium of the Radiation Oncology and Computer Science Departments at the University of North Carolina, BellSouth Corporation, GTE, and the MCNC was formed in response to the high-speed network initiative proposed by the National Science Foundation and the Defense Advanced Research Projects Agency. One of the purposes of this effort has been to demonstrate that applications exist that require gigabit per second networks. Our consortium, known as VISTAnet, proposed to use real-time radiation therapy treatment planning as the application that would require the use of a gigabit network. The plan was to develop a system that could rapidly calculate and display a three-dimensional radiation dose distribution for any configuration of radiation beams. The gigabit network would be used to tie the dose calculations done with the Cray Y-MP at the Research Triangle to the graphics engine at the Department of Computer Science (Pixel-Planes 5) and the medical workstation at Radiation Oncology. The system would then provide the radiation physician with the capability of considering hundreds of potential treatment plans, instead of the usual two or three, with the goal of arriving at a highly optimized plan within a few minutes.

Computer Communication Networks↗
PubMed2002

Exact solution of a drop-push model for percolation.

Motivated by a computer science algorithm known as "linear probing with hashing," we study a new type of percolation model whose basic features include a sequential "dropping" of particles on a substrate followed by their transport via a "pushing" mechanism. Our exact solution in one dimension shows that, unlike the ordinary random percolation model, the drop-push model has nontrivial spatial correlations generated by the dynamics itself. The critical exponents in the drop-push model are also different from those of the ordinary percolation. The relevance of our results to computer science is pointed out.

Journal Article↗
PubMed1996

A programming course in bioinformatics for computer and information science students.

We have created a course entitled "Representations and Algorithms for Computational Molecular Biology" with three specific goals in mind. First, we want to provide a technical introduction for computer science and medical information science students to the challenges of computing with molecular biology data, particularly the advantages of having easy access to real-world data sets. Second, we want to equip the students with the skills required of productive research assistants in molecular biology computing research projects. Finally, we want to provide a showcase for local investigators to describe their work in the context of a course that provide adequate background information. In order to achieve these goals, we have created a programming course, in which three major projects and six smaller assignments are assigned during the quarter. We stress fundamental representations and algorithms during the first part of the course in lectures given by the core faculty, and then have more focused lectures in which faculty research interests are highlighted. The course stressed issues of structural molecular biology, in order to better motivate the critical issues in sequence analysis. The culmination of the course was a challenge to the students to use a version of protein threading to predict which members of a set of unknown sequences were globins. The course was well received, and has been made a core requirement in the Medical Information Sciences program.

Algorithms↗
PubMed1992

Computers in healthcare: overview and bibliography.

OBJECTIVE: The objective of this article is to provide an overview of computer technology and an associated bibliography, emphasizing institutional-based healthcare applications and pharmacoinformatics. DATA SOURCES: References were selected from the authors' files and from a computerized search over the last five years on computers in healthcare/medical informatics and in pharmacy. STUDY SELECTION: Articles selected for review and discussion were considered to be important contributions to the respective areas listed in the bibliography and representative of advancements in computer applications in healthcare and pharmacy. DATA SYNTHESIS: The computer has become an important support tool for healthcare professionals. Medical informatics and the discipline related to pharmacy, called pharmacoinformatics, have evolved from the cognitive underpinnings of medicine, pharmacy, and computer science. Recent developments in computer technology have resulted in computers that are fast, increasingly portable, and user friendly. Hospital information systems employ computers in various ways to deal with the vast amount of information used by various departments. Standards for electronic data exchange are being developed to increase the integration potential of these systems. Hospital pharmacists have used computers for drug distribution, financial analysis and inventory control, drug interaction detection, pharmacokinetic dosing, drug information, and drug therapy monitoring. Expert systems are being developed in several areas of drug therapy. Pharmacy educators have developed interactive courseware to help students learn problem-solving skills in the areas of calculations, therapeutics, and drug information. CONCLUSIONS: Pharmacists need to become more involved with applications of technology to pharmacy. Properly implemented, computers can provide more time for pharmacists to use their cognitive skills in the delivery of pharmaceutical care.

Clinical Pharmacy Information Systems↗
PubMed2000

Measuring and modeling facial affect.

In recent years, researchers in computer science and human-computer interaction have become increasingly interested in characterizing perception of facial affect. Ironically, this applied interest comes at a time when the classic findings on perception of human facial affect are being challenged in the psychological research literature, largely on methodological grounds. This paper first describes two experiments that empirically address Russell's methodological criticisms of the classic work on measuring "basic emotions," as well as his alternative approach toward modeling "facial affect space." Finally, a user study on affect in a prototype model of a robot face is reported; these results are compared with the human findings from Experiment 1. This work provides new data on measuring facial affect, while also demonstrating how basic and more applied research can mutually inform one another.

Adolescent↗
PubMed2002

Usability of expressive description logics--a case study in UMLS.

Research in (medical) terminological knowledge representation is showing an increased interest in the family of Description Logics (DLs), as they allow for automatic reasoning. This interest is driven by an increase in demands on the quality of and reasoning ability with medical terminological knowledge. Recent advances in Computer Science have demonstrated the computational decidability and empirical tractability of quite expressive DLs. The question arises whether this expressivity is usable and useful. This paper motivates and describes an exploratory study to address this question by examining the surplus value of individual DL constructors based on an investigation of UMLS terms. Our study indicates that the disjunction and negation operators comprise very valuable extensions to current DLs. The impact of formalization depends on the involved semantic type; "Injury and Poisoning" is one of the semantic types in which a large portion of concepts will benefit from the extension.

Logic↗
PubMed1991

A paradigm for the next millennium: health information science.

Although historically a major concern of both the artist and the scientist was the observation of nature, the two disciplines split when science became more wedded to mathematics and quantification. Today, with visualization, art and science can again together provide a view of the natural world. A prototype curriculum for a new multidisciplinary science--Health Information Science--incorporates aspects of computer science, cognitive psychology, bioengineering, biomedical visualization, medicine, dentistry, anthropology, mathematics, library science, and the visual arts.

Art↗
PubMed1989

[Hygienic evaluation of artificial lighting in the classroom for studying information science and computer technics in secondary schools].

Body functioning state of schoolchildren was investigated under different lighting conditions of the computer keyboard and video display terminals (VDT). The findings of lighting engineering and physiologic studies showed that optimal conditions for the children working on computers should be ensured by two interdependent indicators, i. e., the level of lighting at the workplace and on VDT. The most favourable indicators of children's visual functions were established at the level of lighting of 400 lx at the workplace and 100 lx on VDT under general luminescent lighting.

Adolescent↗
PubMed2003

Synergistic science.

Should computational materials science be recognized as a field with a role in the community comparable to computational physics or chemistry? With the emergence of multiscale modelling, the answer is a resounding 'yes'.

Computer Simulation↗
PubMed2026

Artificial intelligence-driven advancements in agricultural biotechnology.

The need for faster and more informative data processing for better decision-making is driving the adoption of artificial intelligence (AI) in the agricultural sector. Thanks to recent advancements in computer science and the increase in computational powers of modern computers, AI is not only augmenting traditional solutions, but also helping in developing novel solutions to existing challenging matters. AI-driven models have an exceptional ability to identify patterns and combine a diverse collection of data together and make inference. The increasing pressure on farmlands posed by the growing global population and climate change is lessening growth, yield, and productivity ultimately posing risk to food security worldwide. Incorporation of AI in agriculture has the potential to drive farming efficiency to new heights. This comprehensive review critically evaluates the evolution of AI in agricultural biotechnology from a theoretical concept to a global phenomenon. A comprehensive literature search was performed using major scientific databases, including PubMed, Web of Science, Embase, Scopus, Lens and the Cochrane Library. In this review, we empirically demonstrate the fields advancement toward more capable AI systems and discuss the current applications of AI across crop improvement and precision agriculture such as crop improvement and genetic engineering, genomic selection and plant breeding, pest and disease detection, precision agriculture and smart farming, soil health and nutrient management, climate resilient crop development, livestock biotechnology, challenges and ethical considerations in AI based agricultural biotechnology. Furthermore, this review addresses the exponential growth of commercial intellectual property in the field and contrast it with academic publication outputs. Finally, we critically assess the ethical challenges impeding equitable adoption of AI including data sovereignty and digital divide, while projecting future frontiers involving quantum computing. This review will help build sustainable agricultural systems capable of adapting to climate change, contribute to the development of climate-resilient and high-yielding crops, and address global food security challenges.

Agriculture↗
PubMed1986

[Conservative therapy of forearm fracture in the growth stage with special reference to the correlation of roentgenologic course, objective and subjective total results].

143 out of 310 patients in the age of one to 18 years suffering from forearm-shaft-fractures could be followed up at the 2nd Department of Traumatology, University of Vienna, out of a period between 1978 and 1983. A correlation between radiologic follow-ups and objective/subjective findings was achieved by means of the WAMASTAT/SAS program at the Institute of Medical Computer Sciences. With the aid of computer diagrams of the angulation of fracture-dislocation awaited restrictions of movement can be anticipated. Corrective reductions performed in time can prevent disalignment and improve long-term follow-up results.

Adolescent↗
PubMed1999

From molecular to modular cell biology.

Cellular functions, such as signal transmission, are carried out by 'modules' made up of many species of interacting molecules. Understanding how modules work has depended on combining phenomenological analysis with molecular studies. General principles that govern the structure and behaviour of modules may be discovered with help from synthetic sciences such as engineering and computer science, from stronger interactions between experiment and theory in cell biology, and from an appreciation of evolutionary constraints.

Action Potentials↗