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Results for “Vision, Entoptic”

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At least 127 records · Page 7Linked to original sources
PubMed2004

Sustained perimacular vascular and visual response to topical beta blockers in normal human eyes.

PURPOSE: To assess visual and circulatory responses to treatment with topical beta adrenergic antagonists. DESIGN: Institutional prospective randomized clinical trial in normal adults. METHODS: Twenty adults (36 (mean) +/- 8 (S.D.) years) underwent repeated baseline perimetry (Humphrey 30-2), contrast sensitivity (Vector Vision), perimacular microcirculatory studies (Oculix blue-field entoptic simulator), intraocular pressure (IOP), heart rate (HR), and blood pressure (BP) testing. Subjects commenced either timolol 0.5% or betaxolol 0.5% twice daily on day 1, were retested on days 3 and 35, discontinued treatment for 21 days, whereupon repeated tests were performed. Treatment responses were compared by paired t-test. RESULTS: Timolol-treated eyes showed improvement in contrast sensitivity (P=0.03) and pericentral perimetric thresholds (P=0.01), but corresponding increases among betaxolol-treated eyes were significantly higher (P=0.03 and 0.04, respectively, relative to timolol-treated eyes). Leukocyte velocity increased with both drugs, each with post-withdrawal carryover (P< or =0.03). Significant IOP reduction (approximately 2.5 mmHg) occurred in both groups, BP fell 2.8 mmHg among betaxolol-treated subjects (P=0.02), and HR was 2 bpm slower among timolol-treated subjects (P=0.03), but all reverted to baseline values after washout. CONCLUSIONS: Both treatment groups demonstrated significant changes in visual function and perimacular hemodynamics, sustained after the terminal 3-week washout period.

Administration, Topical↗
PubMedDate not supplied

Visual complaints from healthy children.

It is common for healthy children with specific visual complaints to be seen for eye examinations. After a complete eye examination has ruled out pathologic conditions as the cause of these complaints, it is appropriate for the clinician to explore the possibility that normal entoptic or physiologic visual phenomena might have provoked the child's report of vision problems. Some of these normal visual experiences are frequent causes of children's complaints of vision problems, such as physiologic diplopia, relaxation of the near synkinesis during reading, and vitreous body floaters. Some complaints are common, even though the underlying entoptic or physiologic phenomenon may be speculative or obscure, such as the report that objects look bigger or smaller than they actually are. When the clinician encounters such situations, the parents and the child will be much more satisfied by an explanation of the normal system anatomy and physiology than by the simple reassurance that everything is all right.

Accommodation, Ocular↗
PubMed1997

Association of retinal capillary perfusion with visual status during chronic glaucoma therapy.

PURPOSE: The purpose of the study is to determine whether retinal microcirculation is associated with the degree of visual function in glaucomatous eyes receiving chronic bilateral medical therapy with topical beta-blockers. METHODS: A nonrandomized, 3-year prospective clinical study was undertaken on 37 patients with glaucoma and normal visual acuity receiving symmetric topical medication in both eyes. Humphrey 30-2, Henson CFA 2000, and Vistech 3 and 6 cycles/degree contrast sensitivity were obtained bilaterally at multiple visits, along with Oculix 1000 blue-field estimates of perimacular leukocyte velocity. The mean asymmetry of measurements obtained throughout the treatment period for each pair of eyes was determined, and correlations were obtained to assess visual function asymmetry circulatory asymmetry. RESULTS: Significant associations were observed between blue-field entoptic capillary leukocyte velocity measurements and those for all three visual function testing methods, the eye with the superior vision typically having the higher mean leukocyte velocity (P < 0.001 for both Humphrey mean deviation and Henson perimetry, P < 0.002 for Humphrey corrected pattern standard deviation, and P < 0.02 for contrast sensitivity at both 3 and 6 cycles/degree). CONCLUSIONS: Central retinal microcirculation is associated with various measures of central and peripheral visual function in glaucomatous eyes receiving beta-adrenergic blocker therapy.

Administration, Topical↗
PubMed1970

Entoptic halos.

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Adolescent↗