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At least 127 records · Page 7Linked to original sources
PubMed1992

Comparison between end-systolic pressure-volume and end-systolic wall stress in determining left ventricular contractility with increased afterload.

This study compared end-systolic pressure-volume relationship (P/V) versus wall stress index (WS) as a tool for the evaluation of ventricular contractile state during upright isometric exercise. Both indices of contractility exhibit significant (p < 0.001) increase during exercise compared to resting values. The correlation coefficients for the two indices of contractility were r = -0.45 for exercise and r = -0.70 for rest. Both were significant at the p < 0.01 level. The correlation of the difference scores between rest and exercise as computed by both indices was low (-0.20) and insignificant. These data suggest that changes in contractility from rest to exercise as measured by one index do not reflect the pattern of individual differences that are measured by means of the other index. However, from a reliability point of view, it seems appropriate to prefer the use of P/V index over the WS index in order to determine contractile state.

Adult↗
PubMed2004

Peak atrial systolic mitral annular velocity by Doppler tissue reliably predicts left atrial systolic function.

Left atrial (LA) function assessment is important in clinical practice. We studied peak atrial tissue velocity (A') and quantitative echocardiographic methods of LA function in 120 patients (54 men; mean age 58 years) who were in sinus rhythm. Patients were divided into 2 groups: patients with increased left ventricular mass; and healthy subjects. There was no difference for peak late filling velocity (A) and A velocity time integral between groups. Patients with increased left ventricular mass had higher A', LA ejection fraction, LA ejection force, and LA kinetic energy. A' correlated well with LA ejection fraction (r = 0.8), LA ejection force (r = 0.87), and LA kinetic energy (r = 0.87). A' could also assess LA function for patients with depressed left ventricular function. Subsequently, we assessed A' in 16 patients with restrictive physiology and found that A' also correlated well with quantitative methods of LA function. A' correlates well with quantitative methods of LA function, and could be readily applied for quantifying LA contribution to diastolic performance in clinical practice.

Adult↗