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At least 127 records · Page 7Linked to original sources

Human auditory cortical mechanisms of sound lateralization: II. Interaural time differences at sound onset.

Neuromagnetic responses were recorded over the right temporal cortex using a 24-channel gradiometer. Stimuli were binaural click trains, presented with six separate interaural time differences (ITDs). N100m to sound onset was larger and earlier for stimuli presented with left- than with right-leading ITDs. With stimulus lateralization taken into account, monaural and binaural stimuli evoked responses of roughly equal amplitude. In selective adaptation and oddball experiments, stimuli presented with different ITDs excited overlapping neuronal populations, but the amount of overlap decreased as the ITD between the stimuli increased. There were no systematic differences in the cortical source locations of the N100m as a function of ITD, however. Thus it appears that ITD-sensitive neurons in the human auditory cortex are not organized into a large-scale, orderly representation, which could be resolved by MEG.

Acoustic Stimulation↗

Differences between sound scattering by weakly scattering spheres and finite-length cylinders with applications to sound scattering by zooplankton.

A modeling study was conducted to determine the conditions under which fluidlike zooplankton of the same volume but different shapes (spherical/cylindrical) have similar or dramatically different scattering properties. Models of sound scattering by weakly scattering spheres and cylinders of finite length used in this analysis were either taken from other papers or derived and herein adapted for direct comparison over a range of conditions. The models were examined in the very low- (ka << 1, kL << 1), moderately low- (ka << 1, kL > or = 1), and high-frequency regions (ka >> 1, kL >> 1), where k is the acoustic wave number, a is the radius (spherical or cylindrical) of the body, and L is the length of the cylinders (for an elongated body with L/a = 10, "moderately low" corresponds to the range 0.1 < or = ka < or = 0.5). Straight and bent cylinder models were evaluated for broadside incidence, end-on incidence, and averages over various distributions of angle of orientation. The results show that for very low frequencies and for certain distributions of orientation angles at high frequencies, the averaged scattering by cylinders will be similar, if not identical, to the scattering by spheres of the same volume. Other orientation distributions of the cylinders at high frequencies produce markedly different results. Furthermore, over a wide range of orientation distributions the scattering by spheres is dramatically different from that of the cylinders in the moderately low-frequency region and in the Rayleigh/geometric transition region: (1) the Rayleigh to geometric scattering turning point occurs at different points for the two cases when the bodies are constrained to have the same volume and (2) the functional dependence of the scattering levels upon the volume of the bodies in the moderately low-frequency region is quite often different between the spheres and cylinders because of the fact that the scattering by the cylinders is still directional in this region. The study demonstrates that there are indeed conditions under which different shaped zooplankton of the same volume will yield similar (ensemble average) scattering levels, but generally the shape and orientation distribution of the elongated bodies must be taken into account for accurate predictions.

Acoustics↗

Phase locking of auditory-nerve fibers to the envelopes of high-frequency sounds: implications for sound localization.

Although listeners are sensitive to interaural time differences (ITDs) in the envelope of high-frequency sounds, both ITD discrimination performance and the extent of lateralization are poorer for high-frequency sinusoidally amplitude-modulated (SAM) tones than for low-frequency pure tones. Psychophysical studies have shown that ITD discrimination at high frequencies can be improved by using novel transposed-tone stimuli, formed by modulating a high-frequency carrier by a half-wave-rectified sinusoid. Transposed tones are designed to produce the same temporal discharge patterns in high-characteristic frequency (CF) neurons as occur in low-CF neurons for pure-tone stimuli. To directly test this hypothesis, we compared responses of auditory-nerve fibers in anesthetized cats to pure tones, SAM tones, and transposed tones. Phase locking was characterized using both the synchronization index and autocorrelograms. With both measures, phase locking was better for transposed tones than for SAM tones, consistent with the rationale for using transposed tones. However, phase locking to transposed tones and that to pure tones were comparable only when all three conditions were met: stimulus levels near thresholds, low modulation frequencies (<250 Hz), and low spontaneous discharge rates. In particular, phase locking to both SAM tones and transposed tones substantially degraded with increasing stimulus level, while remaining more stable for pure tones. These results suggest caution in assuming a close similarity between temporal patterns of peripheral activity produced by transposed tones and pure tones in both psychophysical studies and neurophysiological studies of central neurons.

Acoustic Stimulation↗

Functional organization of sound direction and sound pressure level in primary auditory cortex of the cat.

1. The functional organization of neuronal tuning to the azimuthal location and sound pressure level (SPL) of noise bursts was studied in high-frequency primary auditory cortex (AI) of barbiturate-anesthetized cats. Three data collection strategies were used to map neural responses: 1) electrode penetrations oriented normal to the cortical surface provided information on the radial organization of neurons' responses; 2) neurons' responses were examined at a few points in the middle cortical layers in multiple normal penetrations across AI to produce fine-grain maps of azimuth and level selectivity; and 3) electrode penetrations oriented tangential to the cortical surface provided information on neurons' responses along the isofrequency dimension. 2. An azimuth-level data set was obtained for each single- or multiple- (multi-) unit recording; this consisted of responses to noise bursts at five SPLs (0-80 dB in 20-dB steps) from seven azimuthal locations in the frontal hemifield (-90 to +90 degrees in 30 degrees steps; 0 degree elevation). An azimuth function was derived from these data by averaging response magnitude over all SPLs at each azimuth tested. A preferred azimuth range (PAR; range of azimuths over which the response was > or = 75% of maximum) was calculated from the azimuth function and provided a level-independent measure of azimuth selectivity. Each PAR was assigned to one of four azimuth preference categories (contralateral-, midline-, ipsilateral-preferring, or broad/multipeaked) according to its location and extent. A level function obtained from the data set (responsiveness averaged over all azimuths) was classified as monotonic if it showed a decrease of < or = 25% (relative to maximum) at the highest SPL tested (usually 80 dB), and nonmonotonic if it showed a decrease of > 25%. The percentage reduction in responsiveness, relative to maximum, at the highest level tested (termed nonmonotonic strength) and the preferred level range (PLR; range of SPLs over which responsiveness was > or = 75% of maximum) of each response was also determined. 3. Normal penetrations typically showed a predominance of one azimuth preference category and/or level function type. The majority of penetrations (26/36: 72.2%) showed statistically significant azimuth preference homogeneity, and approximately one-half (17/36: 47.2%) showed significant level function type homogeneity. Over one-third (13/36) showed significant homogeneity for both azimuth preference and level function type. 4. Mapping experiments (n = 4) sampled the azimuth and level response functions at two or more depths in closely spaced normal penetrations that covered several square millimeters of AI.(ABSTRACT TRUNCATED AT 400 WORDS)

Animals↗

Sound localization in a small passerine bird: discrimination of azimuth as a function of head orientation and sound frequency.

Sound localization is critical to communication when signalers are distributed widely in space and when reverberations that accumulate over distance might otherwise degrade temporal patterns in vocalizations. We readdress the accuracy with which a small passerine bird, the eastern towhee, Pipilo erythrophthalmus L., is able to resolve azimuth in the field. We then report results from two-alternative forced-choice (2AFC) experiments in which three of four subjects were able to discriminate an estimated speaker separation angle of approximately 7 degrees . Subjects oriented laterally when discriminating azimuth in the 2AFC task and each subject preferred a different head orientation. Side biases occurred as a function of head orientation and, as a consequence, we conducted a second 2AFC experiment in which subjects were required to discriminate between two closely spaced lights. Subjects oriented similarly in this visual task, however, side biases did not occur as a function of head orientation. Despite side biases in the auditory task, performance generally declined when subjects were played tones with frequencies near approximately 3 kHz.

Animal Communication↗

[Spectral analysis of sounds produced by musical instruments and other sounding bodies for hearing screening of children].

Some time ago audiological screening in infants was mostly performed using musical instruments or equivalents. The use of acoustic evoked potentials and oto-acoustic emissions changed the strategies of hearing assessment in newborns and infants, however, musical instruments are still in use. An adequate interpretation of screening results obtained with musical instruments necessitates a profound knowledge of frequencies and intensities derived from these instruments. In this study spectral analyses of sounds from these instruments were performed. The results may be of value for those using musical instruments as a tool for audiological screening. In addition, the results show that with some instruments intensities able to cause inner ear damage can be generated.

Child↗

Analysis of speech sounds is left-hemisphere predominant at 100-150ms after sound onset.

Hemispheric specialization of human speech processing has been found in brain imaging studies using fMRI and PET. Due to the restricted time resolution, these methods cannot, however, determine the stage of auditory processing at which this specialization first emerges. We used a dense electrode array covering the whole scalp to record the mismatch negativity (MMN), an event-related brain potential (ERP) automatically elicited by occasional changes in sounds, which ranged from non-phonetic (tones) to phonetic (vowels). MMN can be used to probe auditory central processing on a millisecond scale with no attention-dependent task requirements. Our results indicate that speech processing occurs predominantly in the left hemisphere at the early, pre-attentive level of auditory analysis.

Acoustic Stimulation↗

Annual cycle of bacterial specific biovolumes in howe sound, a canadian west coast fjord sound.

The mean specific biovolumes (biovolume cell) of the bacterioplankton within a 250-m-deep water column in Howe Sound, British Columbia, were determined for the period of 4 September 1984 to 23 October 1985. These bacteria had an annual cycle in mean specific biovolume; they were small (ca. 0.058 mum) in mid-winter, larger in spring (ca. 0.076 mum), larger again in summer (up to 0.102 mum), and largest (ca. 0.133 mum) in early fall (immediately after the decrease in phytoplankton production). The mean specific biovolumes changed coincidently through the water column with time, although the larger bacterioplankton tended to occur in the surface and deepest water. Although the mean specific biovolumes correlated better with in situ temperature (r = 0.65, a = 0.01) than with in situ chlorophyll a concentration (r = 0.34, a = 0.25), modeling experiments with batch cultures of the dinoflagellate Prorocentrum minimum (Pavillard) and the green alga Dunaliella tertiolecta (Butcher) indicated that the biomass and physiological condition of the phytoplankters may be more important than temperature in determining these bacterial specific biovolumes.

Journal Article↗

Sound pressure correlates of the Austin Flint murmur. An intracardiac sound study.

Mitral valve motion and pressure correlates of the Austin Flint murmur (AFM) were investigated in nine patients with aortic regurgitation using high fidelity catheter tip micromanometers and the mitral valve echocardiogram (MVE). External phonocardiography demonstrated a mid-diastolic murmur (MDM) in eight subjects and a presystolic murmur (PSM) in five. Maximum intensity of both AFM components was found in the left ventricular (LV) inflow tract; the murmur was not recordable in the left atrium (LA). In two patients, an apparent AFM was recorded in the intracardiac phonocardiogram when absent externally. Only one subject had a significant late diastolic "reversed" or LV to LA gradient; in this patient, presystolic mitral regurgitation was shown angiographically but no PSM was present and MVE revealed absence of atriogenic mitral valve re-opening. In two subjects, a PSM disappeared from the external phono when a "reversed" gradient occurred during the diastolic pause following a ventricular premature systole; this LV to LA gradient was associated with diastolic mitral regurgitation recordable in the left atrial phono. In two patients, LV inflow phono showed the MDM to begin 80-120 msec after the aortic second sound and during the D to E phase of the MVE. The rate of early diastolic mitral valve closure in patients (152 +/- 24 mm/sec) was not significantly different from 13 normals (232 +/- 10 mm/sec). With regard to the genesis of the AFM, the present study concludes: 1) diastolic mitral regurgitation plays no role, and 2) antegrade mitral valve flow is required but simultaneous retrograde aortic flow may also be necessary.

Aortic Valve Insufficiency↗

Scent and sound of vision: expressing scent or sound as visual forms.

This article describes three experiments on the possibility of expressing scent or sound into visual forms made by design engineering students. The hypothesis tested was that people are able to pick up patterns in the energy flow that the students transposed from one perceptual sense to another. In Exp. 1 subjects were given different scents and were asked to choose a sculpture designed according these scents. In Exp. 2 subjects were given different musical pieces and asked to match them with portable cassette players designed according to this music. Exp. 3 was identical to Exp. 2 but different music selections, similar to the ones in Exp. 2, were used. In all three experiments subjects were indeed able to perform the tasks above chance level. Results are discussed within the framework of the theory of direct perception of Gibson.

Arousal↗