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At least 127 records · Page 7Linked to original sources

US of the shoulder: rotator cuff and non-rotator cuff disorders.

Ultrasonography (US) has been shown to be an effective imaging modality in the evaluation of both rotator cuff and non-rotator cuff disorders, usually serving in a complementary role to magnetic resonance imaging of the shoulder. US technique for shoulder examination depends on patient positioning, scanning protocol for every tendon and anatomic part, and dynamic imaging. The primary US signs for rotator cuff supraspinatus tendon tears are tendon nonvisualization for complete tears, focal tendon defect for full-thickness tears, a hypoechoic defect of the articular side of the tendon for an articular-side partial-thickness tear, and flattening of the bursal surface of the tendon for a bursal-side partial-thickness tear. Secondary US signs such as cortical irregularity of the greater tuberosity and joint and subacromial-subdeltoid bursal fluid are helpful when correlated with the primary signs. Tendon degeneration, tendinosis, and intrasubstance tear are demonstrated as internal heterogeneity. Long-head biceps tendon abnormalities include instability, acute or chronic tear, and tendinosis. The acromioclavicular joint is assessed for dislocation, fluid collection, cysts, and bone erosions. Other non-rotator cuff disorders include synovial disorders such as adhesive capsulitis and synovial osteochondromatosis; degenerative disorders such as osteoarthritis, amyloid arthropathy, hemarthrosis, and chondrocalcinosis; infectious disorders such as septic arthritis and bursitis; and space-occupying lesions.

Humans↗

Angiographic evidence of long-axis rotation in addition to short-axis aortopulmonary rotation: its implication in transposition of the great arteries.

To assess the pattern of aortic sinus in varied aortopulmonary rotations and its clinical implications, three aortic sinuses at the diastolic phase in true lateral view are identified in 53 angiograms of complete transposition of the great arteries recorded between 1988 and 1993. The patients with the high takeoff of the coronary arteries found at surgery and in the literature were selected for additional investigation. Six regions were defined on the horizontal plane. From left anterior 89 degrees to 61 degrees, the non-facing sinus moved toward the anterior aspect (one patient). From left anterior 60 degrees to left anterior 1 degree, the left-hand sinus moved gradually from an anterior toward a posterior location (two patients). From directly anterior 0 degree to right anterior 59 degrees, the right-hand sinus moved from posterior toward an anterior position (30 patients). From right anterior 60 degrees to right posterior 105 degrees, the non-facing sinus moved posteriorly (20 patients). On approaching directly anterior 0 degree and toward right anterior 60 degrees, the left-hand sinus was the lowest in anterior transposition of the great arteries instead of the non-facing sinus, as in left anterior 90 degrees and in posterior transposition of the great arteries. High takeoff occurred commonly above the lowest left-hand sinus in anterior transposition of the great arteries (2 cases here and 5 in the literature, 100%). In conclusion, aortopulmonary rotations about the short and long axes were both evident on identification of the aortic sinus in various rotations. The aortic sinus did not rotate along the long-axis in anterior transposition of the great arteries, thus making the left-hand sinus, the lowest of this group, vulnerable to the high takeoff of the coronary arteries in anterior transposition of the great arteries.

Aorta↗

A two-population model of rat rotational behavior: effects of unilateral nigrostriatal 6-hydroxydopamine on striatal neurochemistry and amphetamine-induced rotation.

Rats received intrastriatal or intranigral injections of 6-hydroxydopamine (6-OHDA) on the same side towards which they made most of their turns during a previous test of amphetamine-induced rotational behavior. One week later they were retested for amphetamine-induced rotational behavior and it was found that only approximately half of them increased their rotational behavior towards the lesioned side more than non-lesioned controls. In fact, compared to their pre-operative behavior numerous rats decreased or actually reversed their net turning towards the lesioned side. While the post-lesion rotational behavior of the two groups of rats was clearly different, pre-operative turning was not. Furthermore, the neurochemical effects of the intracerebral 6-OHDA injections were not different in the two groups of rats, either with respect to the magnitude of the resulting dopamine (DA) depletion, or with respect to the compensatory increase in the turnover of DA by surviving DA neurons on the lesioned side. The data are discussed in terms of their lack of support for current notions about the role of nigrostriatal DA in turning, and in terms of their support for a two-population model we have previously proposed. An additional, unrelated, finding from the present work was that bilateral striatal serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) levels decreased bilaterally one week following unilateral intrastriatal administration of 6-OHDA.

Animals↗

The detection of stimuli rotating in depth amid linear motion and rotation distractors.

In three experiments, observers watched displays consisting of two or more areas that contained unidirectionally moving pixels. In half of the displays, one area of pixels contained movement that corresponded to the projection of the front surface of a rotating cylinder. The total duration of the displays and the number of stimulus areas per display were varied. The subjects' task was to indicate whether or not a given display contained rotation. When the display time required to reach 75% accuracy was determined, it was found that the number of stimuli per display had no effect; nor did it interact with other variables. One control experiment eliminated "pixel crowding" at the edges of the rotating cylinders, with little effect on the results. Another control experiment found that the ability to discriminate rotating from linear motion declines with distance away from fixation. A fourth experiment showed that under conditions similar to the first three, subjects can make accurate shape discrimination, thereby suggesting that three-dimensional information contributed to the decisions made in the original experiments. On the basis of these results and previous data, it is suggested that in the present experiments structure was recovered from motion by the short-range process, ad that this recovery engages attention to a relatively constant extent, regardless of the number of stimuli contained in a display. Shape discrimination based on structure from motion may required a more effortful form of attention.

Adult↗

Rotating sample system: an equivalent of a rotating electrode for microliter samples.

Voltammetric experiments in sample droplets of 20 microL volume were carried out with gold ring electrodes microfabricated on Pyrex substrates. The droplet studied was centered and kept in place by a hydrophobic ring deposited on the substrate around the ring electrode, which also ensured that each sample assume a semispherical shape. A small hole in the center of the substrate filled with an agar gel membrane served as a junction. A mild jet of humidified nitrogen gas directed tangentially at the droplet caused it to rotate at a high rate. Cyclic voltammetry and constant-potential electrolysis of potassium ferricyanide were used to characterize this rotating sample system and to calculate diffusion layer thickness. The results clearly demonstrate that rotating of a semispherical microsample placed above a stationary ring electrode with a mild gas jet can be as effective as a rotating electrode system. As a practical example, voltammetric stripping analysis of 20-120 pmol mercuric nitrate samples was performed with a calibration of good linearity (r2 = 0.988) and a time constant for exhaustive electrolysis of approximately 2 min.

Electrochemistry↗

Off-resonance rotating frame spin-lattice NMR relaxation studies of phosphorus metabolite rotational diffusion in bovine lens homogenates.

The rotational diffusion behavior of phosphorus metabolites present in calf lens cortical and nuclear homogenates was investigated by the NMR technique of 31P off-resonance rotating frame spin-lattice relaxation as a means of assessing the occurrence and extent of phosphorus metabolite-lens protein interactions. 31P NMR spectra of calf lens homogenates were obtained at 10 and 18 degrees C (below and above the cold cataract phase transition temperature, respectively) at 7.05 T. Effective rotational correlation times (tau 0,eff) for the major phosphorus metabolites present in cortical and nuclear bovine calf lens homogenates were derived from nonlinear least-squares analysis of R vs omega e (spectral intensity ratio vs precessional frequency about the effective field) data with the assumption of isotropic reorientational motion. Intramolecular dipole-dipole (1H-31P, 31P-31P), chemical shift anisotropy (CSA), and solvent (water) translational intermolecular dipole-dipole (1H-31P) relaxation contributions were assumed in the analyses. In those cases where the limiting value of the spectral intensity ratio failed to reach unity at large offset frequency, a modified formalism incorporating chemical exchange mediated saturation transfer between two sites was used. Values of tau 0,eff for phosphorus metabolites present in the cortex varied from a low of ca. 2 ns [L-alpha-glycero-phosphocholine (GPC)] to a high of 12 ns (alpha-ATP) at 10 degrees C, whereas at 18 degrees C the range was from ca. 1 to 9 ns. For the nucleus the tau 0,eff values ranged from ca. 3 ns (GPC) to 41 ns (Pi) at 10 degrees C; at 18 degrees C the corresponding values ranged from 4 to 39 ns. For PME (phosphomonoester; in lens the predominant metabolite is L-alpha-glycerol phosphate) at 18 degrees C evidence was obtained for binding and subsequent exchange with solid like protein domains. The diversity in tau 0,eff values for lenticular phosphorus metabolites is suggestive of differential binding to more slowly tumbling macromolecular species, most likely lens crystallin proteins. Corresponding measurement of tau 0,eff values for the mobile protein fraction present in calf lens cortical and nuclear homogenates at 10 and 18 degrees C, by 13C off-resonance rotating frame spin-lattice relaxation, provided average macromolecular correlation times that were assumed to represent the bound metabolite state. A fast-exchange model (on the T1 time scale), between free and bound forms, was employed in the analysis of the metabolite R vs omega e curves to yield the

Animals↗

Subunit rotation of ATP synthase embedded in membranes: a or beta subunit rotation relative to the c subunit ring.

ATP synthase F(o)F(1) (alpha(3)beta(3)gammadelta epsilon ab(2)c(10-14)) couples an electrochemical proton gradient and a chemical reaction through the rotation of its subunit assembly. In this study, we engineered F(o)F(1) to examine the rotation of the catalytic F(1) beta or membrane sector F(o) a subunit when the F(o) c subunit ring was immobilized; a biotin-tag was introduced onto the beta or a subunit, and a His-tag onto the c subunit ring. Membrane fragments were obtained from Escherichia coli cells carrying the recombinant plasmid for the engineered F(o)F(1) and were immobilized on a glass surface. An actin filament connected to the beta or a subunit rotated counterclockwise on the addition of ATP, and generated essentially the same torque as one connected to the c ring of F(o)F(1) immobilized through a His-tag linked to the alpha or beta subunit. These results established that the gamma epsilon c(10-14) and alpha(3)beta(3)deltaab(2) complexes are mechanical units of the membrane-embedded enzyme involved in rotational catalysis.

Actins↗

Granular ripples under rotating flow: a new experimental technique for studying ripples in non-rotating, geophysical applications?

A review of our research investigating a new pattern formation process in granular material underlying a rotating fluid is given. The purpose of this summary is to introduce the phenomenon to the geophysical research community and to draw attention to the potential practical benefits of our new experimental method. To this end, the applied and scientific advantages of the technique over traditional studies employing, for instance, water channels, are discussed for the first time. It is shown here that the system rotation in our new technique does not appear to affect the scaling law expressing the dependence of the ripple-pattern wavelength on the governing independent experimental parameters. This suggests that it may become possible to extrapolate appropriate results from rotating to non-rotating systems and, hence, to geophysical environments. Consequently, our new technique may find applications in the context of geophysical research on the formation of sedimentary granular ripple structures.

Complex Mixtures↗

Modeling human vestibular responses during eccentric rotation and off vertical axis rotation.

A mathematical model has been developed to help explain human multi-sensory interactions. The most important constituent of the model is the hypothesis that the nervous system incorporates knowledge of sensory dynamics into an "internal model" of these dynamics. This internal model allows the nervous system to integrate the sensory information from many different sensors into a coherent estimate of self-motion. The essence of the model is unchanged from a previously published model of monkey eye movement responses; only a few variables have been adjusted to yield the prediction of human responses. During eccentric rotation, the model predicts that the axis of eye rotation shifts slightly toward alignment with gravito-inertial force. The model also predicts that the time course of the perception of tilt following the acceleration phase of eccentric rotation is much slower than that during deceleration. During off vertical axis rotation (OVAR) the model predicts a small horizontal bias along with small horizontal, vertical, and torsional oscillations. Following OVAR stimulation, when stopped right- or left-side down, a small vertical component is predicted that decays with the horizontal post-rotatory response. All of the predictions are consistent with measurements of human responses.

Acceleration↗

Restricted rotation in unbridged sandwich complexes: rotational behavior of closo-[Co(eta 5-NC4H4)(C2B9H11)] derivatives.

Rotation about the centroid/metal/centroid axis in ferrocene is facile; the activation energy is 1-5 kcal mol(-1). The structurally similar sandwich complexes derived from closo-[3-Co(eta5-NC4H4)-1,2-C2B9H11] (1) have a different rotational habit. In 1, the cis rotamer in which the pyrrolyl nitrogen atom bisects the carboranyl cluster atoms is 3.5 kcal mol(-1) more stable in energy than the rotamer that is second lowest in energy. This cis rotamer is wide, spanning 216 degrees , and may be split into three rotamers of almost equal energy by substituting the N and the carboranyl carbon atoms adequately. To support this statement, closo-[3-Co(eta5-NC4H4)-1,2-(CH3)2-1,2-C2B9H9] (2), closo-[3-Co(eta5-NC4H4)-1,2-(mu-CH2)3-1,2-C2B9H9] 3, 2-->BF3, and 3-->BF3 have been prepared. Two rotamers are found at low temperature for 2-->BF(3) and 3-->BF3. Compounds 2, 3, and 1-->BF3 behave similarly to 1. Rotational energy barriers and the relative populations of the different energy states are calculated from 1H DNMR spectroscopy (DNMR, dynamic NMR). These results agree with those of semiempirical calculations. Without exception, the cis rotamer is energetically the more stable. The fixed conformation of 1 assists in elucidating the rotational preferences of the [3,3'-Co(1,2-C2B9H11)2]- ion in the absence of steric hindrance; the [3,3'-Co(1,2-C2B9H11)2]- ion is commonly accepted to present a cisoid orientation. Complex 1 is electronically similar to the [3,3'-Co(1,2-C2B9H11)2]- ion. Both have heteroatoms in the pi ligands, and they have the same electronegativity difference between the constituent atoms. This leads to a view of the [NC4H4]- as [7,8-C2B9H11]2- ion, with no steric implications. Therefore the [3,3'-Co(1,2-C2B9H11)2]- ion should be considered to have a cisoid structure, and the different rotamers observed to be the result of steric factors and of the interaction of the counterion with either B-H groups and/or ancillary ligands. The rotamer adopted is the one with the atoms holding the negative charges furthest apart.

Journal Article↗

Triazolam blocks the initial rotational effects of quinpirole but permits the later developing reduction of dopamine D2-mediated rotational behavior and dopamine D2 receptors.

Continuous infusion of the dopamine D2 receptor agonist quinpirole into mice with unilateral striatal 6-hydroxydopamine lesions initially produces a supersensitive rotational behavior. This is followed by reductions of dopamine D2-mediated behavior and dopamine D2 receptors. In this study we attempted to determine if it is possible to inhibit the acute increase in D2-mediated behavior while still allowing the reduction of D2-mediated behavioral responses and dopamine D2 receptors to occur. Mice were implanted with Alzet minipumps containing either quinpirole alone or quinpirole combined with the GABA receptor modulator triazolam or the dopamine D2 receptor antagonist sulpiride, and rotational behavior was monitored for the 6 days of infusion. The pumps were then removed, and D2 receptors in striatal membranes were determined. Triazolam completely blocked the initial rotational behavior normally induced by implanting quinpirole. However, the quinpirole-induced reduction of D2-mediated behavioral responses and D2 receptors still occurred. Continuous infusion of sulpiride also inhibited the rotational behavior produced by quinpirole, but it prevented the reduction of dopamine D2 receptors. We conclude that up-regulated dopamine receptors and dopaminergic behaviors can be reversed by the continuous administration of a dopamine receptor agonist and that this reversal can occur without producing an initial exacerbation of dopaminergic responses. These results suggest that this type of treatment regimen might be useful for treating clinical conditions associated with dopaminergic supersensitivity.

Analysis of Variance↗

Congenital radio-ulnar synostosis: compensatory rotation around the wrist and rotation osteotomy.

In order to make clear the clinical features of congenital radio-ulnar synostosis, compensatory rotation around the wrist and functional results after rotation osteotomy, 40 cases of congenital radio-ulnar synostosis have been analysed. The mean pronation of the ankylosed forearm in those who complained of disabilities in daily life was 60.7 degrees and that in patients without complaints was 21.2 degrees. In almost all cases with total ankylosis, the forearm had compensatory movement around the wrist, the mean arc being from 76.3 degrees of pronation to 42.9 degrees of supination. 13 limbs in 11 patients treated by transverse rotational osteotomies through the fusion mass have followed up for over two years. The functional results after surgery were satisfactory in all patients. Rotational osteotomy of the forearm is a useful and reliable treatment for congenital radio-ulnar synostosis.

Adolescent↗

Analysis of rotation-driven electrokinetic flow in microscale gap regions of rotating disk systems.

In the present study, a novel theoretical model is developed for the analysis of rotating thermal-fluid flow characteristics in the presence of electrokinetic effects in the microscale gap region between two parallel disks under specified electrostatic, rotational, and thermal boundary conditions. The major flow configuration considered is a rotor-stator disk system. Axisymmetric Navier-Stokes equations with consideration of electric body force stemming from streaming potential are employed in the momentum balance. Variations of the fluid viscosity and permittivity with the local fluid temperature are considered. Between two disks, the axial distribution of the electric potential is determined by the Poisson equation with the concentration distributions of positive and negative ions obtained from Nernst-Planck equations for convection-diffusion of the ions in the flow field. Effects of disk rotation and electrostatic and thermal conditions on the electrokinetic flow and thermal characteristics are investigated. The electrohydrodynamic mechanisms are addressed with an interpretation of the coupling nature of the electric and flow fields. Finally, solutions with electric potential determined by employing nonlinear or linearized Poisson-Boltzmann equation and/or invoking assumptions of constant properties are compared with the predictions of the present model for justification of various levels of approximation in solution of the electrothermal flow behaviors in rotating microfluidic systems.

Journal Article↗

Effects of rotational symmetry order on the solid state dynamics of phenylene and diamantane rotators.

The rotational dynamics of phenylene and diamantane rotators in crystals of 1,9-bis(4-[3,3,3-triphenylpropynyl]phenyl)diamantane were analyzed independently within the same crystal structure. The dynamics of phenylene rotation were established by dynamic line shape analysis using 13C CPMAS NMR. The phenylene signals were selectively highlighted by deuteration of the aromatic trityls and the use of short contact times for cross polarization. The dynamics of the diamantane group were established by 1H spin-lattice relaxation under conditions where dipolar relaxation was shown to be the dominant mechanism between 250 and 425 K. A factor of 20 000 between the rates of rotation of the faster diamantane and the slower phenylene at 300 K supports expectations that higher symmetry rotors should have significantly faster dynamics.

Journal Article↗

Rotationally resolved electronic spectra of 2- and 3-methylanisole in the gas phase: a study of methyl group internal rotation.

Rotationally resolved fluorescence excitation spectra of several torsional bands in the S1 <-- S0 electronic spectra of 2-methylanisole (2MA) and 3-methylanisole (3MA) have been recorded in the collision-free environment of a molecular beam. Some of the bands can be fit with rigid rotor Hamiltonians; others exhibit perturbations produced by the coupling between the internal rotation of the methyl group and the overall rotation of the entire molecule. Analyses of these data show that 2MA and 3MA both have planar heavy-atom structures; 2MA has trans-disposed methyl and methoxy groups, whereas 3MA has both cis- and trans-disposed substituents. The preferred orientations (staggered or eclipsed) in two of the conformers and the internal rotation barriers of the methyl groups in all three conformers change when they are excited by light. Additionally, the values of the barriers opposing their motion depend on the relative positions of the substituent groups, in both electronic states. In contrast, no torsional motions of the attached methoxy groups were detected. Possible reasons for these behaviors are discussed.

Journal Article↗

Anisotropy of photofragment recoil as a function of dissociation lifetime, excitation frequency, rotational level, and rotational constant.

Quantum mechanical calculations of photofragment angular distributions have been performed as a function of the frequency of excitation, the lifetime of the dissociative state, the rotational level, and the rotational constant. In the limit of high J values and white, incoherent excitation, the general results are found to agree exactly with both those of Mukamel and Jortner [J. Chem. Phys. 61, 5348 (1974)] and those of Jonah [J. Chem. Phys. 55, 1915 (1971)]. Example calculations describe how the anisotropy is dependent on the degree of broadening, the rotational constant, the initial rotational level, and the frequency of excitation. Applications are also made to interpret experimental results on the photodissociation of ClO via the 11-0, 10-0, and 6-0 bands of the A 2Pi3/2 -X 2Pi3/2 transition and on the photodissociation of O2 via the 0-0 band of the E 3Sigmau- -X 3Sigmag- transition.

Journal Article↗

Approximation of rotational strengths from molar rotation data and generation of rotatory dispersion curves for d-camphor-10-sulfonate.

Starting with the expression for optical rotatory dispersion in the absorption region that was arrived at by Condon, two series were considered for the purpose of achieving the experimentally observed, steeper wavelength dependence in the absorption region while retaining the established 1/lambda(2) law in regions removed from absorption. The first two terms of one series in which the second term exhibits a 1/lambda(6) wavelength dependence were found to calculate satisfactorily the optical rotatory dispersion curve of d-camphor-10-sulfonate from 400 mmu to 190 mmu when only three bands were considered. Evaluated at the extrema, the two-term expression can be approximated by a simple equation which allows calculation of the rotational strength of a nonoverlapping band by using only the wavelength and molar rotation of the extrema and the index of refraction of the solution. The rotational strengths calculated from optical rotatory dispersion data in this manner closely agree with those calculated from corresponding circular dichroism data. Thus when position and magnitude of rotatory dispersion extrema alone are reported for carbonyls, it is suggested that such published data may be converted to approximate rotational strengths.

Camphor↗

A comparison of rotating slant hole collimator and rotating camera for single photon emission tomography of the heart.

Measurements were made on the tomographic imaging abilities of a rotating slant hole collimator and a rotating scintillation camera system using a standard heart phantom and thallium-201. This allowed a comparison to be made between these and published results for conventional imaging and the seven pinhole technique under standardised conditions. Although better intraplanar resolutions were obtained with the rotating slant hole, the rotating camera was found to give superior definition of a defect and less propagation between reconstructed sections of the phantom.

Heart↗