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Results for “RODENT DISEASES”

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At least 127 records · Page 7Linked to original sources
PubMed1992

Comparative study of long, segmented, filamentous organisms in chickens and mice.

No transmission of long, segmented, filamentous organisms (LSFO) from a laboratory mouse strain (Mus musculus) to a domestic broiler chicken strain (Gallus domesticus) occurred by oral dosing with mouse mucosal and fecal preparations, even in hydrocortisone-treated chicks. Transmission of chicken LSFO to laboratory mice was attempted, but the results were confounded by the mice having been already infected with LSFO. However, the morphologic characteristics of the LSFO in the dosed mice suggested that transmission of chick LSFO did not occur. Mouse LSFO, as detected in carbol thionin-stained mucosal smears, are generally wider, longer, and have slightly different morphologic characteristics than chicken LSFO. The results of these studies suggest that the LSFO in mice and chickens may be two distinct species.

Animals↗
PubMed2005

Ornithonyssus (Acari: Macronyssidae) mite dermatitis in poultry field-workers in Almarg, Qalyobiya governorate.

Cutaneous manifestations of bird and rat mite infestation in man are not easily recognized by physicians or patients. Clinical signs and symptoms are developed secondary to bites of mites that have infested rats, domestic poultry or birds nesting in or near human habitation and comes into contact with man. This study details 4 cases of pruritic dermatitis developed in four field workers in poultry farms in Al-Marg district, Qalyobia governorate, Egypt. The zoonotic species of Ornithoyssus sp., (Family Macronyssidae) was isolated from all samples collected from patients' habitat and the role played by Ornithonyssus mites in causing dermatitis in man was discussed.

Acari↗
PubMed1991

[The genetic classification of the Pasteurella pneumotropica complex].

Pasteurella pneumotropica with its biotypes Jawetz and Heyl are the most common bacterial pathogens associated with diseases in rodents. 23 P. pneumotropica biotype Jawetz, biotype Heyl and P. pneumotropica-like rodentia isolates have been investigated phenotypically by characterization of their micromorphology and biochemical fermentation reactions. The taxonomic position within the family Pasteurellaceae has been examined by DNA:DNA hybridisation (optical method). It could be shown that P. pneumotropica biotype Jawetz represents a genus-like cluster containing several species including the V-factor dependent Haemophilus Taxon B and the avian P. pneumotropica-like organism and therefore resembles a new species of the new genus. It is concluded that the biotype Heyl of P. pneumotropica taxonomically remains as a species within the family Pasteurellaceae, however without further relationship to other known genera or genus-like groups.

Animals↗
PubMed1991

Acute toxicity of crude extracts of Aspergillus quadrilineatus isolated from acha (Digitaria exilis Stapf).

In a survey of fungi and mycotoxin conterminating acha (Digitaria exilis Stapf) in Plateau State of Nigeria, 96 fungal isolates were made. Screening of the fungi isolates for their mycotoxin-producing potentials showed that Aspergillus quadrilineatus (Thom and Raper) produced some of the most toxic mycotoxins. Two extracts of the Aspergillus quadrilineatus (the petroleum ether soluble extracts [PER] and the petroleum ether defatted crude extract [PEDCR]) were tested for acute toxicity in mice, chicks and cattle. The ip LD50 of PER in mice was 1148 mg/kg, and the oral LD50 of PEDCR was 566 mg/kg in mice and 556 mg/kg in chicks. The ip LD50 of PEDCR in mice was 21 mg/kg. The toxic signs of PER and PEDCR in mice and chicks included tachypnea, tachycardia, anorexia, somnolence, diarrhea, coma and death. The main postmortem findings were congestion of heart, liver, kidney and lungs and sloughing of the wall of stomach and hemorrhagic enteritis. The histopathologic findings in dead animals included edema and mild degeneration of the myocardium and necrosis of kidney tubular epithelial cells, hepatocytes and bronchioles. The only clinical observation in 1 calf orally dosed with a culture of Aspergillus quadrilineatus of maize was transient whole body tremors which occurred 1 h after dosing, tachycardia and profuse salivation. No significant histopathologic changes were found in the organs of the sacrificed calf.

Animals↗
PubMed1977

[Human myopathy and animal muscular dystrophy].

Two hereditary muscular dystrophies similar to human progressive muscular dystrophy (P.M.D. Duchenne type) have been isolated in animals, one in mouse, the other in chicken. The decrease in the activity of glycogenolytic enzymes is similar to that observed in denervated muscle. Isozymic fetal types for several muscular enzymes have been observed as well in chicken as in man, but this fetal type may also be found in neurogenic atrophy. The release in circulation of muscle enzymes seems more specific. But the origin of the genetic lesion is still unknown. We describe here the three different theories about this problem: i.e. neurogenic, vascular, or myogenic. This last theory implies a trouble of membrane permeability.

Adenosine Triphosphate↗
PubMed1988

Experimental nasal dermatitis in the Mongolian gerbil: effect of bilateral harderian gland adenectomy on development of facial lesions.

Two groups of adult Mongolian gerbils (Meriones unguiculatus) of mixed ages and sex were used to study the effect of bilateral Harderian gland adenectomy on development of nasal dermatitis. One group of gerbils underwent bilateral Harderian gland adenectomies, while the other group underwent sham surgeries, leaving the Harderian gland intact. All animals in both groups were fitted with Elizabethian collars to prevent self-grooming, allowing a buildup of nasolacrimal or Harderian gland secretions near the medial canthus of the eye and at the external nares. Twenty-six of 27 animals with intact Harderian glands developed nasal and facial lesions within 20 days. None of the 27 Harderian gland adenectomized animals developed nasal or facial lesions. Apparently, accumulation of Harderian gland secretions is involved in the pathogenesis of nasal dermatitis in the Mongolian gerbil.

Animals↗
PubMed1987

Possible roles of tumor necrosis factor in the pathology of malaria.

The authors have earlier proposed that tumor necrosis factor (TNF) might contribute to the pathology of malaria. Here they report the outcome of injecting recombinant human TNF/cachectin into normal mice and others with low parasitemias (6-35%) of Plasmodium vinckei. The object was to see how precisely the pathologic features of the terminal stages of this infection could be produced, when parasitemias are 70-80%. Hypoglycemia, mid-zonal liver damage, and pulmonary accumulation of neutrophils in the pulmonary vasculature, all of which are seen in severe P vinckei infection, occurred within 4-12 hours after the mildly infected mice received TNF/cachectin. Uninfected mice were much less susceptible. TNF/cachectin also increases plasma lactate, a change seen in both the human and rodent diseases. From these findings and the recent literature on TNF/cachectin, including its detection in serum from malarial patients, it seems likely that excessive release of this monokine could account for certain of the unexplained pathologic features of human malaria.

Animals↗