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At least 127 records · Page 7Linked to original sources

Psychological interventions for distress in cancer patients: a review of reviews.

We review a decade of review articles concerning psychosocial interventions for cancer patients. We find a distinct progression in the tone of interpretations of the literature, as better quality studies accumulate and the sophistication of reviews improves. The current literature does not make a compelling case for the value of these interventions for the typical cancer patient. The bulk of the literature reviews in this field take a narrative rather than a systematic approach, and serious compromises in standards are necessary to muster an adequate set of studies for review. The more rigorous the review, the less likely it is to conclude there is evidence that psychological interventions are effective.

Cognitive Behavioral Therapy↗

Data for peer review: acquisition and use. Results in the experimental medical care review organization program.

Nine Experimental Medical Care Review Organizations (EMCROs) review the process and outcome of medical care, using insurance billing claims or medical record abstracts as the data source. The cost of EMCRO insurance billing claims processing in 1972, including peer review, ranged from $0.47 to $2.50 per claim. Three EMCROs reviewed the necessity for elective hospital admission prospectively for $2.50, $8.50, and $10.02 per case. The EMCROs developed innovative methods for abstracting hospital, nursing home, and ambulatory medical records at a cost of $0.40 to $4.00 per abstract. These EMCRO cost estimates were not derived from uniform accounting methods. Problems of accuracy and comparability of data for peer review are discussed. The EMCRO experience may aid local implementation of Professional Standards Review Organizations (PSROs).

Abstracting and Indexing↗

Systematic review of systematic reviews of acupuncture published 1996-2005.

Systematic reviews of acupuncture have tended to support its use, but few applied rigorous inclusion criteria. We tested the credibility of conclusions of systematic reviews of acupuncture published since 1996 by applying rigorous inclusion criteria. Reinterpretation used randomised and double blind trials with valid outcomes or design, and with information available from at least four trials or from 200 patients. Qualified support for acupuncture was originally reported in 12 out of 35 systematic reviews, and strong support was found in another six. Applying stricter inclusion criteria, however, showed that none of the 35 reviews supported acupuncture, predominantly because there were too few patients in the randomised, double blind studies. Six reviews with more than 200 patients in randomised, double blind studies had good evidence of no benefit. Systematic reviews of acupuncture have overstated effectiveness by including studies likely to be biased. They provide no robust evidence that acupuncture works for any indication.

Acupuncture Therapy↗

Reviewing the reviews: the example of chronic fatigue syndrome.

OBJECTIVE: To test the hypothesis that the selection of literature in review articles is unsystematic and is influenced by the authors' discipline and country of residence. DATA SOURCES: Reviews in English published between 1980 and March 1996 in MEDLINE, EMBASE (BIDS), PSYCHLIT, and Current Contents were searched. STUDY SELECTION: Reviews of chronic fatigue syndrome (CFS) were selected. Articles explicitly concerned with a specialty aspect of CFS and unattributed, unreferenced, or insufficiently referenced articles were discarded. DATA EXTRACTION: Record of data sources in each review was noted as was the departmental specialty of the first author and his or her country of residence. The references cited in each index paper were tabulated by assigning them to 6 specialty categories, by article title, and by assigning them to 8 categories, by country of journal publication. DATA SYNTHESIS: Of 89 reviews, 3 (3.4%) reported on literature search and described search method. Authors from laboratory-based disciplines preferentially cited laboratory references, while psychiatry-based disciplines preferentially cited psychiatric literature (P = .01). A total of 71.6% of references cited by US authors were from US journals, while 54.9% of references cited by United Kingdom authors were published in United Kingdom journals (P = .001). CONCLUSION: Citation of the literature is influenced by review authors' discipline and nationality.

Authorship↗

Are road safety evaluation studies published in peer reviewed journals more valid than similar studies not published in peer reviewed journals?

The peer review system of scientific journals is commonly assumed to prevent seriously flawed research from getting published. This paper compares the quality of 44 road safety evaluation studies published in peer reviewed journals to the quality of 79 evaluation studies dealing with the same safety measures, but not published in peer reviewed journals, in terms of seven criteria of study validity. Studies were scored for validity in terms of (1) sampling technique, (2) total sample size, (3) mean sample size for each result, (4) specification of accident or injury severity, (5) study design, (6) number of confounding factors controlled and (7) number of moderator variables specified. Confounding factors are all factors that disturb the attribution of a causal relationship between the safety measure being evaluated and the observed changes in safety, moderator variables are all variables that influence the size of the effect of the safety measure. Very few statistically reliable differences in study validity were found between studies published in peer reviewed journals and studies not published in such journals. There was, at best, a weak tendency for studies published in peer reviewed journals to score higher for validity. An interaction was found between author affiliation and type of publication with respect to study validity. Studies published in peer reviewed journals by authors who were at a university scored highest for validity. For a number of reasons, this study must be regarded as exploratory and its results as indicative only. The study does, however, point to a line of research that might be worth pursuing in larger and more rigorous studies.

Automobile Driving↗

Reviewer bias against the unconventional? A randomized double-blind study of peer review.

OBJECTIVE: To test the hypothesis that there is a reviewer bias against publication of a test of an unconventional drug. DESIGN: Randomized, controlled, double-blind study of peer review. PARTICIPANTS: Convenience sample of 291 medical doctors from a wide variety of specialties drawn from a list of conference participants. METHODS: Reviewers were randomly assigned to receive one of two versions of a manuscript. Version M related to an in-vitro experiment on a mainstream drug (Metoprolol). The otherwise identical version V used a highly unconventional drug (beef spleen cell extract) for the same experiment. Reviewers were asked to complete a standardised evaluation sheet including visual analogue scales (VASs) on a set of predefined quality criteria. All participants were debriefed after completion of the study. RESULTS: The response rate was 61%. There were no significant differences in VAS ratings between the two versions of the manuscript. Ratings covered the entire range of the VASs. CONCLUSION: In the present setting, there was no evidence for a reviewer-bias against testing an unconventional drug. The low inter-rater reliability, however, suggested inadequate validity of peer review.

Animals↗

Quality assurance reviews: how they differ from peer reviews.

Research papers and reports written by scientists and engineers in the United States Environmental Protection Agency are reviewed by the agency's quality assurance staff. EPA papers and reports are subjected to peer reviews that check for the validity of conclusions and the general agreement with the body of technical knowledge in the subject area. Quality assurance reviews differ from peer reviews in that the focus of the quality assurance review is on the following criteria: Consistency: Were reasonable and consistent units of measurement and generally acceptable formulas used throughout? Are the appropriate number of significant figures reported? Correctness: Were matrix-compatible methods used? Were measurements within the working range of the method? Can measurements be traced to a recognized standard or source (e.g., the National Institute of Standards and Technology)? Can calculations be verified, starting from representative raw data and proceeding to the summary data presented in the paper or report? Coherence: Do the stated conclusions follow from the data presented? Are the assumptions clearly stated? Are inconsistencies between data and conclusions discussed? Clarity: Are special terms and acronyms defined? Can a person with a general technical background in the subject understand the paper or report? Conformance: Did the study follow the test/quality assurance plan, with appropriate calibrations and other quality-control checks, audits, and data validations? If not, is there a discussion of problems? Concordance: Were data quality objectives met? Were the data quality indicator goals achieved for precision, accuracy, representativeness, comparability, and completeness? The importance of these quality assurance review criteria are discussed along with examples from current work.

Authorship↗

Lumbar supports for prevention and treatment of low back pain: a systematic review within the framework of the Cochrane Back Review Group.

STUDY DESIGN: A systematic review of randomized and nonrandomized controlled trials. SUMMARY OF BACKGROUND DATA: Lumbar supports are used in the treatment of low back pain, but also to prevent the onset (primary prevention) or recurrences of a low back pain episode (secondary prevention). OBJECTIVES: To assess the effects of lumbar sup-ports for prevention and treatment of nonspecific low back pain. METHODS: The Medline, Cinahl, and Current Contents databases; the Cochrane Controlled Trials Register up to September 1999; and the Embase database up to September 1998 were all searched. References of identified trials and systematic reviews were reviewed and the Science Citation Index used to identify additional trials. Methodologic quality assessment and data extraction were performed by two reviewers independently. A quantitative analysis was performed in which the strength of evidence was classified as strong, moderate, limited or conflicting, and no evidence. RESULTS: Five randomized and two nonrandomized preventive trials and six randomized therapeutic trials were included in the review. Only 4 of the 13 studies were of high quality. There was moderate evidence that lumbar supports are not effective for primary prevention. No evidence was found on the effectiveness of lumbar supports for secondary prevention. The systematic review of therapeutic trials showed that there is limited evidence that lumbar supports are more effective than no treatment, whereas it is still unclear whether lumbar supports are more effective than other interventions for treatment of low back pain. CONCLUSIONS: There continues to be a need for high quality randomized trials on the effectiveness of lumbar supports. One of the most essential issues to tackle in these future trials seems to be the realization of adequate compliance.

Braces↗

Back schools for nonspecific low back pain: a systematic review within the framework of the Cochrane Collaboration Back Review Group.

STUDY DESIGN: A systematic review within the Cochrane Collaboration Back Review Group. OBJECTIVES: To assess the effectiveness of back schools for patients with nonspecific low back pain (LBP). SUMMARY OF BACKGROUND DATA: Since the introduction of the Swedish back school in 1969, back schools have frequently been used for treating patients with LBP. However, the content of back schools has changed and appears to vary widely today. METHODS: We searched the MEDLINE and EMBASE databases and the Cochrane Central Register of Controlled Trials to November 2004 for relevant trials reported in English, Dutch, French, or German. We also screened references from relevant reviews and included trials. Randomized controlled trials that reported on any type of back school for nonspecific LBP were included. Four reviewers, blinded to authors, institution, and journal, independently extracted the data and assessed the quality of the trials. We set the high-quality level, a priori, at a trial meeting six or more of 11 internal validity criteria. Because data were clinically and statistically too heterogeneous to perform a meta-analysis, we used a qualitative review (best evidence synthesis) to summarize the results. The evidence was classified into four levels (strong, moderate, limited, or no evidence), taking into account the methodologic quality of the studies. We also evaluated the clinical relevance of the studies. RESULTS: Nineteen randomized controlled trials (3,584 patients) were included in this updated review. Overall, the methodologic quality was low, with only six trials considered to be high-quality. It was not possible to perform relevant subgroup analyses for LBP with radiation versus LBP without radiation. The results indicate that there is moderate evidence suggesting that back schools have better short- and intermediate-term effects on pain and functional status than other treatments for patients with recurrent and chronic LBP. There is moderate evidence suggesting that back schools for chronic LBP in an occupational setting are more effective than other treatments and placebo or waiting list controls on pain, functional status, and return to work during short- and intermediate-term follow-up. In general, the clinical relevance of the studies was rated as insufficient. CONCLUSION: There is moderate evidence suggesting that back schools, in an occupational setting, reduce pain and improve function and return-to-work status, in the short- and intermediate-term, compared with exercises, manipulation, myofascial therapy, advice, placebo, or waiting list controls, for patients with chronic and recurrent LBP. However, future trials should improve methodologic quality and clinical relevance and evaluate the cost-effectiveness of back schools.

Humans↗

Risk in emergency research using a waiver of/exception from consent: implications of a structured approach for institutional review board review.

OBJECTIVE: To apply component analysis, a structured approach to the ethical analysis of risks and potential benefits in research, to published emergency research using a waiver of/exception from informed consent. The hypothesis was that component analysis could be used with a high degree of interrater reliability, and that the vast majority of emergency research would comply with a minimal-risk threshold. METHODS: A Medline search and manual search were done to identify studies using a waiver of/exception from informed consent published between July 1996 and December 2000. A review panel of physicians and bioethicists independently classified nontherapeutic procedures in each study as minimal risk, probably minimal risk, or probably more than minimal risk. RESULTS: Seventy studies using a waiver of/exception from informed consent were identified. A majority of reviewers classified nontherapeutic procedures in 62 studies (88.6%) as minimal risk. Reviewers classified nontherapeutic procedures in six studies (8.6%) as minimal risk or probably minimal risk. In two studies (2.9%), nontherapeutic procedures were classified as probably more than minimal risk. The intraclass correlation coefficient was 0.89 (95% CI = 0.85 to 0.93), indicating very high interrater reliability. CONCLUSIONS: Component analysis can be used with high reliability to review emergency research and may improve the consistency of institutional review board review of emergency research. The vast majority of published emergency research performed using a waiver of/exception from consent complies with a properly-applied minimal-risk threshold. A minimal-risk threshold for nontherapeutic procedures protects subjects better than current U.S. regulations while permitting important emergency research to continue.

Algorithms↗

Life review reminiscence in the elderly: a review of the literature.

The literature on life review reminiscence in the elderly is reviewed. Research indicates that life review is a personal, self-evaluative form of reminiscence with intrapersonal and interpersonal dimensions. The nature and quality of these dimensions change with age. The process and outcome of life review in the elderly may vary as a function of independent, as compared with institutional, living. There needs to be closer correspondence between clinical and research endeavors since empirical documentation is lacking regarding the efficacy of life review groups. It is suggested that an integration of intrapersonal and interpersonal approaches may provide the basis for a broad conceptualization of life review reminiscence in aged adults.

Aged↗

An illustrative example of infant and child death review in South Dakota: "the 1998 annual report of the Regional Infant and Child Mortality Review Committee".

Local, regional, or state infant and child death review teams provide an excellent mechanism for identifying risk factors for infant and childhood deaths along with establishing a conduit for effecting preventive measures to reduce the number of deaths in these particularly vulnerable age groups. In 1997, a predecessor of the current Regional Infant and Child Mortality Review Committee was established in Minnehaha County as South Dakota's first non-Indian review committee for infant and childhood deaths. The 1998 Review Committee's annual report to the public is presented in this paper as an illustration of what can be expected from such a committee along with the specific public health concerns identified and their potential remedies. Especially noted in the committee's 1998 report is an alarming increase in Sudden Infant Death Syndrome (SIDS) death in the region and the educational role the Back to Sleep Campaign can play in the prevention of SIDS. The annual report serves as an example to illustrate how local review mechanisms can identify community strategies that may promote the health and well being of infants and children in their review areas.

Adolescent↗

How do peer reviewers of journal articles perform? Evaluating the reviewers with a sham paper.

Peer review process is widely used to assess the quality of scientific research and select papers for publication in biomedical journals. The method lacks standardization and objectivity. To standardize the peer review process, evaluation and rating of the performance of individual peer reviewers using a sham paper is suggested. The present study of 7 reviewers revealed ratings ranging from 0.34 (SD 0.33) to 0.45 (SD 0.5), widely differing from the set standard (ideal 0). This indicates less than optimal performance by the peer reviewers. Feedback to the peer reviewers might help in improving the standards.

Evaluation Studies as Topic↗

Current status of biomedical book reviewing. I. Key biomedical reviewing journals with quantitative significance.

This is the first part of a comprehensive, quantitative study of biomedical book reviewing. The data base of the total project was built from statistics taken from all 1970 issues of biomedical journals held in the Science Library of the Massachusetts Institute of Technology. Of 285 so-called "life sciences" journals held by that library, fifty-four English journals (excluding Science and Nature) were found to contain bona fide book reviews (as contrasted with mere author-title lists) and were therefore selected for close study. The statistical results reveal that there were 3,347 reviews of 2,067 biomedical books in these fifty-four selected journals in 1970. Part I of the study identifies key biomedical reviewing journals of quantitative significance. The top ten journals, British Medical Journal, Lancet, Annals of Internal Medicine, Journal of the American Medical Association, Archives of Internal Medicine, New England Journal of Medicine, Quarterly Review of Biology, Bioscience, Canadian Medical Association Journal,(*) and American Journal of the Medical Sciences, accounted for 63.03% of the total number of reviews in 1970.

Book Reviews as Topic↗