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A combined analysis of North American case-control studies of residential radon and lung cancer.

Cohort studies have consistently shown underground miners exposed to high levels of radon to be at excess risk of lung cancer, and extrapolations based on those results indicate that residential radon may be responsible for nearly 10-15% of all lung cancer deaths per year in the United States. However, case-control studies of residential radon and lung cancer have provided ambiguous evidence of radon lung cancer risks. Regardless, alpha-particle emissions from the short-lived radioactive radon decay products can damage cellular DNA. The possibility that a demonstrated lung carcinogen may be present in large numbers of homes raises a serious public health concern. Thus, a systematic analysis of pooled data from all North American residential radon studies was undertaken to provide a more direct characterization of the public health risk posed by prolonged radon exposure. To evaluate the risk associated with prolonged residential radon exposure, a combined analysis of the primary data from seven large scale case-control studies of residential radon and lung cancer risk was conducted. The combined data set included a total of 4081 cases and 5281 controls, representing the largest aggregation of data on residential radon and lung cancer conducted to date. Residential radon concentrations were determined primarily by a-track detectors placed in the living areas of homes of the study subjects in order to obtain an integrated 1-yr average radon concentration in indoor air. Conditional likelihood regression was used to estimate the excess risk of lung cancer due to residential radon exposure, with adjustment for attained age, sex, study, smoking factors, residential mobility, and completeness of radon measurements. Although the main analyses were based on the combined data set as a whole, we also considered subsets of the data considered to have more accurate radon dosimetry. This included a subset of the data involving 3662 cases and 4966 controls with a-track radon measurements within the exposure time window (ETW) 5-30 yr prior to the index date considered previously by Krewski et al. (2005). Additional restrictions focused on subjects for which a greater proportion of the ETW was covered by measured rather than imputed radon concentrations, and on subjects who occupied at most two residences. The estimated odds ratio (OR) of lung cancer generally increased with radon concentration. The OR trend was consistent with linearity (p = .10), and the excess OR (EOR) was 0.10 per Bq/m3 with 95% confidence limits (-0.01, 0.26). For the subset of the data considered previously by Krewski et al. (2005), the EOR was 0.11 (0.00, 0.28). Further limiting subjects based on our criteria (residential stability and completeness of radon monitoring) expected to improve radon dosimetry led to increased estimates of the EOR. For example, for subjects who had resided in only one or two houses in the 5-30 ETW and who had a-track radon measurements for at least 20 yr of this 25-yr period, the EOR was 0.18 (0.02, 0.43) per 100 Bq/m3. Both estimates are compatible with the EOR of 0.12 (0.02, 0.25) per 100 Bq/m3 predicted by downward extrapolation of the miner data. Collectively, these results provide direct evidence of an association between residential radon and lung cancer risk, a finding predicted by extrapolation of results from occupational studies of radon-exposed underground miners.

Adult↗

Multiple radon entry modeling in a house with a cellar.

Combining a computational fluid dynamics (CFD) model and a multi-zonal model, a study was carried out on radon entry through the complex substructure of a house with a cellar. The uniqueness of the radon entry problem in this type of house was due to the involvement of two radon entry routes to two chambers: the cellar and the living area of the house. Soil gas carrying radon was driven through the two routes by two coupled disturbance pressures in the chambers. The effects of temperature differences were considered as another driving force for the radon entry. Examined in this study were the effects of the geometry of the substructure, air permeability of the soil, air-tightness of the cellar shell, and cellar ventilation on radon entry to both the cellar and the living area. The ground floor covering on top of the soil outside a cellar wall increased radon entry through this wall by about 68%, as radon built up to a very high level under the covering. The effect of cellar ventilation was found as follows: the cellar ventilation created a layer of airflow in the soil under the ground floor; the flow passed over a crack in the ground floor, the entry route to the living area, diluting the radon in the area. Hence, the soil gas entering the living area carried less radon. Cellar ventilation seems more effective in reducing radon entry to the living area in a more permeable soil and leaky cellar shell; a moderate cellar ventilation condition achieved 77% reduction in radon entry to the area. When permeability of these two materials was lower and soil radon content remained the same, the chances of radon entry was also lower; hence, the indoor radon level was lower and no radon control was needed. When such soil contains high radon concentration, other mitigation measures must be sought.

Air Pollutants, Radioactive↗

210Po implanted in glass surfaces by long term exposure to indoor radon.

Recent epidemiologic investigations of the relationship between residential radon gas exposure and lung cancer relied on contemporary radon gas measurements to estimate past radon gas exposures. Significant uncertainties in these exposure estimates can arise from year-to-year variation of indoor radon concentrations and subject mobility. Surface implanted 210Po has shown potential for improving retrospective radon gas exposure estimates. However, in previous studies, the ability of implanted 210Po activity to reconstruct cumulative radon gas exposure was not tested because glass was not available from homes with known radon-gas concentration histories. In this study, we tested the validity of the retrospective radon gas reconstruction using implanted 210Po surface activity by measuring glass surfaces from homes whose annual-average radon gas concentrations had been measured almost every year during two decades. Regression analysis showed a higher correlation between measured surface activity and cumulative radon gas exposure in these homes (R2>0.8) than was observed in homes where only contemporary radon gas measurements were available. The regression slope (0.57 ky m(-1)) was consistent with our earlier retrospective results. Surface activity measurements were as reliable for retrospective radon gas exposure reconstruction as yearlong gas measurements. Both methods produced estimates that were within 25% of the long-term average radon gas concentrations in a home. Surface measurements can be used for home screening tests because they can provide rapid, reliable estimates of past radon gas concentrations. Implanted 210Po measurements are also useful in retrospective epidemiologic studies that include participants who may have been exposed to highly variable radon concentrations in previously occupied or structurally modified homes.

Air Pollution, Indoor↗

The effectiveness of radon remediation in Irish schools.

An advisory reference level of 200 Bq m(-3) and a statutory reference level of 400 Bq m(-3) apply to radon exposure in Irish schools. Following the results of a national survey of radon in Irish schools, several hundred classrooms were identified in which the reference levels were exceeded and a remediation program was put in place. This paper provides an initial analysis of the effectiveness of that remediation program. All remediation techniques proved successful in reducing radon concentrations. Active systems such as radon sumps and fan assisted under-floor ventilation were generally applied in rooms with radon concentrations above 400 Bq m(-3). These proved most effective with average radon reduction factors of 9 to 34 being achieved for radon sumps and 13 to 57 for fan assisted under-floor ventilation. Both of these techniques achieved maximum radon reduction factors in excess of 100. The highest average reduction factors were associated with the highest initial radon concentrations. Passive remediation systems such as wall and window vents were used to increase background ventilation in rooms with radon concentrations below 400 Bq m(-3) and achieved average radon reductions of approximately 55%. Following the installation of active remediation systems, the radon concentration in adjacent rooms, i.e., rooms in which the radon concentration was already below 200 Bq m(-3) and therefore did not require remediation, was further reduced by an average of 25%. The long-term effectiveness of a number of radon sump systems with at least three years operation showed no evidence of fan failures. This study showed an apparent increase in sump effectiveness with time as indicated by an increase in radon reduction factors during this period.

Air Pollutants, Radioactive↗

Protection against radon-222 at home and at work. A report of a task group of the International Commission on Radiological Protection.

The Commission has used an epidemiological basis for the assessment and control of radon exposure in this report. Since all the available epidemiological studies use the quantity inhaled potential alpha energy, this has been used as the primary quantity in this report. The Commission does not recommend the use of the dosimetric human respiratory model (ICRP, 1994) for the assessment and control of radon exposures. The Commission sees practical advantages in the delineation of radon-prone areas where more buildings than usual have elevated radon levels. For dwellings, it is suggested that areas with more than 1% of buildings with radon concentrations exceeding ten times the national average concentration might be designated as radon-prone, but the choice will depend on local conditions. A similar approach might be adopted in non-residential areas. Action against radon should be focused on such radon-prone areas. The imperatives of intervention against adventitious exposure to radon in buildings are clear. Above appropriate action levels, intervention is practicable and usually more cost-effective than other investments in radiological protection. Two types of building need to be considered, dwellings and workplaces. In both cases, radon concentrations are most likely to be elevated by the ingress of soil gas from the subjacent ground. Preventive and remedial measures to avoid this circumstance are recommended. The action levels adopted should fall within the recommended range of values given in Table 7. Proven measures against radon are readily available. For remedial work, the technical procedure that is most likely to maintain the radon level to a value well below the action level should be adopted from the outset. Intervention should take place soon after the discovery of elevated levels, especially if the concentrations are substantially above the action levels adopted by the competent authority. For preventive work, construction codes and building guides should be devised that will consistently achieve low concentrations of radon in the completed buildings. In workplaces, both in buildings and underground, where the radon concentrations remain above the recommended action level after any appropriate remedial measures have been taken, the Commission's system of protection should be applied and radon should be treated in the same way as any other radioactive material at work. The relevant data on conversion coefficients are given in Table 6 and the main quantitative recommendations are summarised in Table 7. Corresponding values in historical units are given in Table 8.

Air Pollution, Indoor↗

Indoor radon survey in dwellings of nine cities in the Eastern and the Western provinces of Saudi Arabia.

The results of a first phase of an indoor radon survey in a total of 1610 dwellings distributed in nine cities of the Eastern and the Western provinces of Saudi Arabia are presented. The objective of this radon survey was to obtain representative indoor radon data for seven cities in the Eastern province. Khafji, Hafr Al-Batin, Abqaiq, Qatif, Al-Ahsa, Dammam and Khobar and to compare this with two cities in the Western province, Madina and Taif. So far, detailed radon data is not available for Saudi Arabia: therefore, this radon survey provides a base line for Saudi Arabia in the Radon World Atlas. On average, 200 indoor radon dosemeters were distributed in each city and placed for a period of one year starting from May 2001 to May 2002. The total number of collected dosemeters was 847. A total of 724 houses and 98 schools were covered in this survey. The results of the survey in the cities showed that the overall minimum, maximum and average radon concentrations were 1, 137 and 22 Bq m(-3), respectively. Geometric mean and geometric standard deviations of the radon distribution were found to be 18 and 1.92, respectively. In one of the dwellings in Qatif city, radon concentration, measured by a passive system and then confirmed by an active system, was found to be 535 +/- 23 and 523 +/- 22 Bq m(-3), respectively. The result of a radon survey in 98 schools showed that the minimum, maximum and average radon concentrations were 1, 70 and 19 Bq m(-3), respectively. The average radon concentration for each city was also determined. The lowest average radon concentration (8 Bq m(-3)) was found in Al-Ahsa while the highest average concentration (40 Bq m(-3)) was found in Khafji.

Air Pollutants, Radioactive↗

Anomalous indoor radon concentration in a dwelling in Qatif City, Saudi Arabia.

An indoor radon survey was carried out recently in nine cities of Saudi Arabia using nuclear track detectors (NTD)-based passive radon detectors. The survey included Qatif City in the Eastern Province of Saudi Arabia, where 225 detectors were collected back successfully. It was found that the average indoor radon concentration in the dwellings was 22 +/- 15 Bq m(-3). However, one of the dwellings showed an anomalous radon concentration of 535 +/- 23 Bq m(-3). This finding led to a detailed investigation of this dwelling using active and passive techniques. In the active technique, an AlphaGUARD 2000 PRQ radon gas analyser was used. In the passive technique, CR-39 based passive radon detectors were used in all the rooms of the dwelling. Radon exhalation from the wall and the floor was also measured using the can technique. The active measurement confirms the passive one. Before placing the passive radon detectors in all the rooms of the two-storey building, the inhabitant was advised to ventilate his house regularly. The radon concentration in the different rooms was found to vary from 124 to 302 Bq m(-3). Radon exhalation from the floor and the wall of the room with the anomalous radon concentration was found to vary from 0.5 to 0.8 Bq m(-2) h(-1). These low radon exhalation rates suggest that the anomalous radon concentration is most probably due to underground radon diffusion into the dwelling through cracks and joints in the concrete floor.

Air Pollutants, Radioactive↗