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Results for “PULPITIS”

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At least 127 records · Page 7Linked to original sources
PubMed1977

Experimental pulpitis in immunized monkeys.

Bovine serum albumin (BSA) was topically applied to exposed dentin to assess whether inflammatory reactions can be induced in the pulp of monkeys immunized against BSA. Four cynomolgus monkeys received repeated injections of BSA emulsified with Freund's incomplete adjuvant. Pulp challenge was performed by applying BSA in freshly cut dentin cavities prepared on the buccal surface in 34 teeth. In 29 control teeth ovalbumin (OVA) was applied. Control applications of BSA were also performed in 15 teeth prepared in three nonimmunized monkeys. Forty-eight hours after the initiation of the pulp challenge the monkeys were sacrificed and the pulp tissue examined in the light microscope. Topical application of BSA to freshly exosed dentin in immunized monkeys resulted in severe inflammatory lesions in the pulp, characterized by bleeding and extravascular infiltration of large numbers of leukocytes. Extensive tissue damage was an important feature in several pulps. Identical applications of OVA in control teeth and BSA applications in nonimmunized monkeys produced no such reactions. The results indicate that interactions between antigens and antibodies can occur within the dentin-pulp area and following the formation of immune-complexes, severe injury to the pulp can be induced.

Administration, Topical↗
PubMed2001

Localized intrinsic staining of teeth due to pulpitis and pulp necrosis in dogs.

Dental charts and records of 71 dogs were received and 84 intact tooth crowns were noted to have been entirely discolored in shades of pink, purple, grey, or tan. Endodontic therapy was performed on 49 of these teeth allowing gross examination of the entire pulp. In exploratory pulpotomy was performed in 15 teeth prior to exodontic therapy in order to assess the integrity of the coronal pulp. Gross signs of partial or total pulp necrosis were present in 59 (92.2%) of these teeth. The pulp was not observed grossly in 20 teeth which received exodontic therapy. Overall, of the 84 teeth evaluated, 36 (42.9%) had no radiographic signs of endodontic disease. Gross or radiographic signs of endodontic disease were absent in only 2 (4.1%) discolored teeth receiving endodontic therapy. Based on the low incidence of vital, affected teeth in the dogs of this study, endodontic on exodontic therapy is recommended for discolored teeth.

Animals↗