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At least 127 records · Page 7Linked to original sources
PubMed2005

New PDS contracts.

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Dentist-Patient Relations↗
PubMed2000

Deafness heterogeneity in a Druze isolate from the Middle East: novel OTOF and PDS mutations, low prevalence of GJB2 35delG mutation and indication for a new DFNB locus.

About 60% of congenital hearing impairment cases in developed countries are due to genetic defects. Data on the molecular basis of hereditary hearing reflects vast genetic heterogeneity. There are >400 disorders in which hearing impairment is one of the characteristic traits of a syndrome. Linkage studies have identified more than 40 human chromosomal loci associated with non-syndromic hearing loss. So far, 16 of these 40 non-syndromic hearing impairment genes have been identified. We have studied the molecular basis of hearing impairment in four Druze families from the same village in Northern Galilee. The Druze are a small, isolated population in the Middle East practising endogamous marriage. Thus it was expected that a single mutation would account for hearing impairments in all these families. Our results show that at least four different genes are involved. Hearing impairment was caused in one family by a novel mutation in the recently identified OTOF (the DFNB9 gene), by a novel Pendred syndrome mutation (Thr193Ile) in another family, and by a GJB2 mutation (35delG also known as 30delG) in the third family. In the fourth family linkage was excluded from all known hearing impairments loci (recessive and dominant) as well as from markers covering chromosomes 11-22, pointing therefore to the existence of another non-syndromic recessive hearing loss (NSRD) locus on chromosomes 1-10.

Carrier Proteins↗
PubMedDate not supplied

[Capsular ligament surgery of the knee joint with resorbable materials. 5-year clinical experience with Vicryl and PDS ligaments].

Current methods of capsular ligament surgery of the knee joint are not sufficient stable. Tensions of unloaded movements of the knee joint are appropriate to destruct again the reconstructed capsular ligament mechanism. Immobilisation is required. Additional capsular ligament plastics produced out of absorbable materials (Polyglactin, Polydioxanon) protect safely the reconstructed capsular ligaments from destruction. Early functional treatment is practicable. The ligament plastics seem to stimulate the nature of origin of ligament-similar tissue. The plastic ligaments will be broken down to natural substances byx hydrolysis. An additional surgical excision is not required. Ligament plastics out of Vicryl are recommended.

Humans↗
PubMed1985

Relations between TMJ pain dysfunction syndrome (PDS) and some psychologic and biographic variables.

A total of 211 persons with a complete natural dentition were examined for signs and symptoms of the TMJ pain dysfunction syndrome. They also answered the questions of the Dutch version of the Hopkins Symptoms Check List (HSCL). Schooling, age and sex were also registered. Signs and symptoms of the TMJ pain dysfunction syndrome proved to be highly correlated to the psychologic and somatic scales of the HSCL with one exception: maximal mouth opening. The total palpation score proved to be a reliable, sensitive, easy and fast predictor for the severity of the TMJ pain dysfunction syndrome.

Adult↗
PubMed1988

Role of psychologic and social variables in TMJ pain dysfunction syndrome (PDS) symptoms.

The aim of this study was to measure the relative importance of a number of psychologic and social variables in explaining the severity of symptoms of functional disturbances of the stomatognathic system. 261 non-care seeking patients with respect to pain and dysfunction of the stomatognathic system were examined. The total sample consisted of two subgroups: Group 1 (n = 130) with a complete natural dentition and Group 2 (n = 131) wearing complete maxillary and mandibular dentures. Symptoms of functional disturbances of the stomatognathic system were assessed using two questionnaires. One was derived from the Anamnestic Dysfunction Index and the other was an extended questionnaire which included accessory symptoms frequently mentioned in the literature. The patients also completed the Hopkins Symptom Checklist, the Dutch Personality Inventory, and a Dutch form of the Minnesota Multiphasic Personality Inventory. In both patient subgroups symptoms of functional disturbances of the stomatognathic system were significantly correlated with patient's sex and a complex of highly intercorrelated psychologic variables: psychoneurotic- and somatic symptoms, neuroticism, negativism, and somatization.

Adult↗
PubMed1988

Relative importance of psychologic and social variables in TMJ pain dysfunction syndrome (PDS) signs.

The aim of this study was to measure the relative importance of a number of psychologic and social variables in explaining the severity of signs of functional disturbances of the stomatognathic system. A group of 261 non care seeking patients with respect to pain and dysfunction of the stomatognathic system were examined. The total sample consisted of two subgroups: Group one (n = 130) with a complete natural dentition and Group two (n = 131) wearing complete maxillary and mandibular dentures. Signs of functional disturbances of the stomatognathic system were assessed using the Clinical Dysfunction Index and a Palpation Test. The patients also completed the Hopkins Symptoms Checklist, the Dutch Personality Inventory and a Dutch form of the Minnesota Multiphasic Personality Inventory. Patient education, age and sex were also registered. In both patient subgroups signs of functional disturbances of the stomatognathic system were significantly correlated with patient's sex and a complex of highly intercorrelated psychologic variables: psychoneurotic and somatic symptoms, neuroticism and somatization.

Adult↗
PubMed1996

Immunohistochemical characterization of monoclonal antibodies (PDs) as markers of the periderm in the developing chicken embryo.

The outermost surface cell layer of the developing embryo, the periderm, arises from the initial single layer of ectoderm and is eventually exfoliated from the stratified epidermis, which has the same ectodermal origin. In this study, monoclonal antibodies against chicken limb bud ectoderm were generated and screened for those which stained the periderm. Four separate antibodies termed PD2, 3, 7 and 9 were obtained from 180 mixed hybridomas. These PD antibodies stained the periderm selectively at all stages examined (stage 20-42). By correlating the results of immunohistochemistry with observations made by transmission electron microscopy, it was revealed that PD antibodies stained both the squamous periderm at an early stage and rounded bulging peridermal cells just before exfoliation. Therefore we feel that PD antibodies may be useful in further systematic investigations of the development and function of the chicken embryonic periderm.

Animals↗