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At least 127 records · Page 7Linked to original sources

Long-term paresthesia following inadvertent forcing of sodium hypochlorite through perforation in maxillary incisor.

During endodontic retreatment of a maxillary central incisor, a midroot buccal perforation was created, and sodium hypochlorite was inadvertently forced through the perforation into surrounding tissue. The consequences of this incident included immediate severe pain and swelling, with the subsequent development of a fistula, and in the long term (15 months), paresthesia of the floor and ala of the nose and the infraorbital area.

Adult↗

Mental nerve paresthesia associated with an amalgam filling: a case report.

We present a case report in which a mental nerve paresthesia occurred in connection with an amalgam filling placed in direct contact with the pulp of a mandibular first molar. The main evidence for amalgam being the dominant etiological factor was the positive epicutaneous patch testing response to the components of the amalgam alloy, and the total remission of symptoms without further clinical complications after removal of the amalgam filling and subsequent endodontic therapy.

Adolescent↗

Mechanisms of paresthesiae, dysesthesiae, and hyperesthesiae: role of Na+ channel heterogeneity.

Paresthesiae, dysesthesiae, and hyperesthesiae ('positive symptoms') result from ectopic nerve impulses secondary to inappropriate membrane excitability which develops in the setting of chronic sensory axonal injury. The molecular changes in the membranes of dorsal root ganglion neurons which underlie ectopic impulse generation as a result of chronic axonal injury are unknown. Preliminary evidence has suggested that voltage-dependent Na+ channels are one of the participants in the production of ectopic impulses, but the precise form of their participation remains to be determined. The present paper reviews normal sensory anatomy and Na+ channel physiology, as well as clinical syndromes heralded by positive sensations and what is so far known about the cellular and molecular mechanisms underlying them. Properties of two distinct populations of Na+ channels native to the DRG neurons which give rise to cutaneous afferents are described. The biophysical properties of each population of Na+ channels must be tuned with respect to the other in order to cooperate in the generation of action potential activity underlying normal sensory function. A novel hypothesis is put forth suggesting that chronic axonal injury leads to intraneuronal heterogeneity of the populations of Na+ channels in cutaneous afferents, as revealed by their characteristic properties. This may result in one population of Na+ channels activating the other, leading to membrane instability, and possibly to ectopic impulse generation.

Axons↗

Paresthesia and back pain in a patient receiving vancomycin during hemodialysis.

A 36-year-old woman was admitted for initiation of hemodialysis for chronic renal failure. Two days after catheter placement the patient developed a fever that persisted and resulted in subsequent removal of the catheter. Although blood cultures were negative, cultures of the catheter tip were positive for Staphylococcus epidermidis. An initial vancomycin dose was well tolerated, but the patient later experienced numbness and tingling of her lower back accompanied by pain ten minutes after initiation of the second dose. Symptoms abated when the vancomycin infusion was discontinued, and the drug was subsequently well tolerated when reinstituted at a slower infusion rate. Similar symptoms were observed five minutes into a vancomycin infusion a week later that also resolved after decreasing the infusion rate. Patients on hemodialysis receiving vancomycin should be carefully monitored during drug administration for the development of paresthesia and spasmodic lower back pain.

Adult↗

Good reduction of paresthesia and pain after excision of excessive callus formation in patients with malunited clavicular fractures.

BACKGROUND AND AIMS: Sequelae following non-surgical treatment of clavicular fractures are not uncommon. The aim with this study was to describe results after excision of excessive callus in patients with late onset of paresthesia/numbness. MATERIAL AND METHODS: Eight patients with hypertrophic callus after a malunited clavicular fracture were operated with removal of excessive callus and scar tissue, without stabilizing ostheosynthesis. The reason for surgery was paresthesia/numbness in the arm and hand. There was a delay between trauma and onset of symptoms on average 10 (6-18) months. Neurophysiology prior to surgery was normal in the patients tested. The mean age at trauma was 29 years and the mean time between trauma and operation was 66 months. A prerequisite for surgery was symptoms without recovery for at least 6 months. RESULTS: At follow-up on average 20 months after surgery the paresthesia/numbness, pain at rest, pain during activity, headache and dizziness were significantly reduced or even gone in all patients. The improvement occurred almost immediately after surgery with no signs of recurrence during follow-up. CONCLUSION: Removal of excessive callus and scar tissue after a malunited clavicular fracture can reduce or fully relieve disabling paresthesia and pain even if surgery is done several years after the fracture. Neurophysiological examination is normal due to lack of permanent neurologic damage and can not be used to confirm the symptoms.

Adult↗

Different effects of 4-aminopyridine on sensory and motor fibers: pathogenesis of paresthesias.

Mammalian motor and sensory fibers respond differently to the potassium channel-blocking agent, 4-aminopyridine (4-AP). The action potentials of the motor fibers increase in duration after 4-AP, while the sensory fibers respond with bursts of action potentials after a single stimulus. These differences may account for the paresthesias reported by patients with multiple sclerosis following treatment with 4-AP.

4-Aminopyridine↗

Lip paresthesia associated with a jaw mass.

A case is reported in which mandibular swelling and lower lip numbness were the first signs of a metastatic adenocarcinoma of the lung. The development of paresthesia, with or without other oral symptoms, requires that a diagnosis of malignancy be considered until confirmed or ruled out by tissue biopsy. A thorough head and neck examination in all patients, especially in those whose history or habits may indicate increased risk of malignancy is necessary.

Adenocarcinoma↗

Diver with acute abdominal pain, right leg paresthesias and weakness: a case report.

A 29-year-old man was brought to an emergency department by the United States Coast Guard with chief complaints of severe abdominal pain, right leg paresthesia and weakness following four deep air dives. Physical examination before recompression treatment was remarkable for diffuse abdominal tenderness and right leg weakness. The patient was diagnosed in the emergency room with type II decompression sickness (DCS) and underwent standard recompression therapy. He experienced complete resolution of weakness after hyperbaric oxygen (HBO) therapy, but his abdominal pain was persistent. Further investigation led to the diagnosis of acute appendicitis with perforation. The patient underwent appendectomy and intravenous antibiotic therapy and was discharged to his home on hospital day five without complications. This case reinforces the importance of careful clinical assessment of divers and illustrates the potentially wide differential diagnosis of DCS. This is the first reported case of recompression treatment of a diver with acute appendicitis and type II DCS.

Abdominal Pain↗

[A case of multiple sclerosis with paroxysmal attacks of facial paresthesia, unilateral hand tremor, epigastric pain and urinary incontinence].

A Japanese woman, aged 42, was admitted because of paroxysmal attacks consisting of paresthesia of the left face, tremor in the right hand, epigastric pain and urinary incontinence. A year prior to the admission, she noticed some difficulty in writing, dysarthria and unsteadiness of walking. These symptoms had been persistent since then. At the end of March, 1991, these symptoms rapidly worsened, and she fell down frequently. She also experienced pain behind both eyes, numbness in her left fingers and toe, urinary frequency and the above-mentioned attacks. Neurological examination disclosed bilateral internuclear ophthalmoplegia and upbeating nystagmus on upward gaze, titubation in the head, scanning speech, dysmetria in all limbs, exaggerated reflexes in jaw and both legs, bilateral extensor plantar reflexes and ankle clonus. SEP showed delayed cortical response with stimulation of the median nerves bilaterally and of the right posterior tibial nerve. P40 was absent with the left posterior tibial nerve stimulation. VEP was normal. T2-weighted image of MRI showed multiple high intensity areas located around the third ventricle, crus cerebri and the right upper part of the pons. The diagnosis of multiple sclerosis was made. Each paroxysmal attack started with numbness in the left face and burning sensation in the neck. Almost simultaneously tremor in the right hand began. The surface EMG showed the rhythmic contractions in the dorsal hand muscles and wrist extensors at a frequency of 6-7 Hz, and sometimes it revealed synchronized contractions of finger flexors and the dorsal hand muscles. A few seconds later she felt painful sensation in the epigastric region, and the tremor gradually increased in its intensity.(ABSTRACT TRUNCATED AT 250 WORDS)

Abdominal Pain↗

[Psychogenic oral paresthesia].

Psychogenic oral paresthesia represent a proteiform condition, more and more frequent. The failure to recognize it can lead to unjustified investigations or/and procedures. These manifestations are secondary to a psychic problem which varies in severity. In most cases, the establishment of a trust relationship, explanations to the patient and eventually a psychotherapy are sufficient to eliminate the symptoms. In severe cases, a psychotherapy or a psychiatric treatment are almost always necessary.

Adult↗

[Paresthesias].

A 23-year-old patient suddenly experienced paresthesia in both legs which progressively ascended to the region of the umbilicus and finally also occurred in all fingers. The physical examination revealed a decreased sensation for touch, discrimination and vibration in all paresthetical regions and on the stem even up to dermatome C5. A mild elevation of the protein content, a mononuclear pleocytosis and oligoclonal bands were found in the cerebrospinal fluid. Magnetic resonance imaging of the cervical spinal cord showed a hyperintensive lesion in the region of the posterior tract at C6. With respect to these findings and after exclusion of other neurological affections, multiple sclerosis was diagnosed. The symptoms subsided spontaneously within five weeks, and the patient was discharged without any complaints. The diagnostic accuracy of the various findings is discussed.

Adult↗

A retrospective study of paresthesia of the dental alveolar nerves.

Paresthesia is a rare clinical finding subsequent to surgery accompanied by the administration of local anesthetics. A small patient population was identified whose clinical problem may be explained by neurotoxicity due to a local anesthetic metabolite. Reasonable questions arise from these clinical observations that would benefit from prospective studies to explain sensory loss on a biochemical basis.

Anesthesia, Dental↗

Permanent paresthesia to sculptured nails. A distressing problem.

In order to discourage her habit of nail biting and to repair her damaged nails, a 50-year-old woman sought cosmetic improvement in a beauty salon, where a manicurist suggested the use of sculptured nails. A permanent paresthesia resulted from this procedure without allergic reaction.

Acrylic Resins↗

[The use of a method of developing and activating artificial stable functional feedbacks of the 2d type for treating patients with paresthesia of the oral mucosa].

A novel technique was applied to treat oral mucosa paresthesia: formation and activation of artificial stable functional connections within the human brain. The method is based upon the activation and impulse stimulation of the brain. The results of treatment suggest high efficacy of the technique leading to prompt disintegration and reduction of the disease.

Acupuncture Therapy↗