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At least 127 records · Page 7Linked to original sources
PubMed1998

[Comparison of anterior rhinomanometry and impulse oscillometry in nasal provocation with histamine].

UNLABELLED: Anterior rhinomanometry (aR) is the standard method for measurement of nasal resistance, but it has some drawbacks because it requires full co-operation of the patient and the results are disturbed by forced ventilation due to stenosis. The patient must generate flow by active ventilation. Resistance results from the flow/pressure ratio. Forced oscillation technique (IOS) does not affect spontaneous breathing. Flow/pressure ratio is generated externally by a loudspeaker. IOS measures not only resistance but also reactance. Whereas former methods used only a single frequency IOS is capable of applying and analysing frequencies between 0 and 100 Hz. The range from 5 to 35 Hz is useful for diagnostic issues. We compared IOS with aR in nasal provocation tests with histamine and checked the sensitivity of resistance (R) and reactance (X) at different frequencies. METHOD: 20 patients (13 m, 7 f) underwent nasal challenge test using increasing doses of histamine (max. 3.2 mg). Resistance (aR, IOS) and reactance (IOS) were measured parallel. To compare the two methods, we calculated the dose of histamine which is required to double nasal resistance. RESULTS: 1. IOS demonstrates the increase of R at all frequencies. 2. The highest increase of R is measured at a frequency of 5 Hz (5 Hz: NaCl 0.41 +/- 0.25; Hist. 1.26 +/- 0.57; 35 Hz: NaCl 0.36 +/- 0.172; Hist. 0.60 +/- 0.1 kPa/l/s, p < 0.001). 3. The critical dose is significantly lower in IOS than in aR (2.29 +/- 2.59 vs. 1.06 +/- 1.16 mg/ml, p < 0.02). 4. Basal values of R do not differ significantly between aR and IOS (0.37 +/- 0.12 vs. 0.41 +/- 0.25 kPa/l/s, p < 0.001). CONCLUSIONS: We conclude from our results that IOS is at least equivalent to aR in measuring nasal resistance. R at 5 Hz is the most important parameter in IOS. IOS is less dependent on the cooperation of the patient. In case of stenosis it does not require forced ventilation to achieve the required flow-pressure ratio.

Adult↗
PubMedDate not supplied

Simultaneous application of differential servo-oscillometry and volume-clamp plethysmography for continuous non-invasive recording of the finger blood pressure response to a hand postural change.

Continuous blood pressure recordings obtained by the volume-clamp method (Finapres 2300 BP monitor, Ohmeda, USA) were compared with measurements made by using the modified oscillometric method (UT9201 beat-to-beat monitor, University of Tartu, Estonia) in normal subjects during a hand postural change. Changes in the local blood pressure were induced in 11 healthy volunteers by passive elevation of the hand by 40 cm and lowering it again after one minute. We did not reveal a statistically significant difference between the group-averaged responses of the oscillometric finger mean blood pressure measurement device and those of Finapres during this test. The difference UT9201 minus Finapres equalled -1.3 +/- 3.1 mm Hg (p = 0.15). Blood pressure responses were similarly tracked by both beat-to-beat finger blood pressure monitors despite the considerable variability in the shape of the subjects' individual responses.

Adult↗
PubMed2004

Report on the course of study BZ-1003-BR following the changes in airways in stutterers with the help of pulse oscillometry (MasterScreen IOS).

Stuttering affects people all over the world. At the age of six years, about 1.5 percent of children suffers from stuttering. Although stuttering resolves spontaneously upon reaching adulthood in approximately 80% of those affected, it continues to have significant health and social consequences. So far, its etiology remains unknown. The organic differences in those with stuttering and those free of speech problems have been evaluated. As a result of these examinations, it has been hypothesized that stuttering results from functional pneumoobstruction of the tracheobronchial tree in the peripheral respiratory passages. As for now, no similar therapeutic procedure, using a bronchodilating agent in the treatment of stuttering, has been described. Preliminary findings of a pilot study are surprisingly positive. In October of 2003, a multicenter open clinical trial (Stage III) to verify the effect of a sympathomimetic agent formoterol was initiated. The study is being realized in six centers in Moravia and enrolls approx. 40 patients (children, adolescents and young adults). First experience and initial evaluation of the cohort are presented here.

Adolescent↗